PL93499B1 - - Google Patents

Download PDF

Info

Publication number
PL93499B1
PL93499B1 PL1975178582A PL17858275A PL93499B1 PL 93499 B1 PL93499 B1 PL 93499B1 PL 1975178582 A PL1975178582 A PL 1975178582A PL 17858275 A PL17858275 A PL 17858275A PL 93499 B1 PL93499 B1 PL 93499B1
Authority
PL
Poland
Prior art keywords
compounds
tetrahydrofurfuryl
formula
mixture
hydroxy
Prior art date
Application number
PL1975178582A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL93499B1 publication Critical patent/PL93499B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL1975178582A 1974-03-09 1975-03-08 PL93499B1 (en16)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
PL93499B1 true PL93499B1 (en16) 1977-05-30

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
PL1975191318A PL93699B1 (en16) 1974-03-09 1975-03-08
PL1975191319A PL93700B1 (en16) 1974-03-09 1975-03-08
PL1975178582A PL93499B1 (en16) 1974-03-09 1975-03-08

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL1975191318A PL93699B1 (en16) 1974-03-09 1975-03-08
PL1975191319A PL93700B1 (en16) 1974-03-09 1975-03-08

Country Status (25)

Country Link
JP (1) JPS5827275B2 (en16)
AT (1) AT344332B (en16)
BE (1) BE826440A (en16)
BG (3) BG24813A4 (en16)
CA (1) CA1049511A (en16)
CH (8) CH612425A5 (en16)
CS (1) CS188221B2 (en16)
DD (1) DD119236A5 (en16)
DE (1) DE2411382C3 (en16)
DK (1) DK137188C (en16)
ES (6) ES440345A1 (en16)
FI (1) FI63571C (en16)
FR (1) FR2262984B1 (en16)
GB (1) GB1496418A (en16)
HU (1) HU177408B (en16)
IE (1) IE40945B1 (en16)
IL (1) IL46760A (en16)
NL (1) NL7502724A (en16)
NO (1) NO141800C (en16)
PH (1) PH14127A (en16)
PL (3) PL93699B1 (en16)
RO (2) RO70051A (en16)
SE (1) SE421919B (en16)
SU (3) SU577982A3 (en16)
ZA (1) ZA751394B (en16)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
WO2009017664A1 (en) 2007-07-26 2009-02-05 Vitae Pharmaceuticals, Inc. CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1
JP5769970B2 (ja) 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
KR20110002492A (ko) 2008-05-01 2011-01-07 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8114868B2 (en) 2008-07-25 2012-02-14 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (en) 2011-08-17 2014-06-25 Boehringer Ingelheim International GmbH Indenopyridine derivatives

Also Published As

Publication number Publication date
ES440345A1 (es) 1977-03-01
DD119236A5 (en16) 1976-04-12
IL46760A (en) 1978-12-17
FR2262984A1 (en16) 1975-10-03
SU577983A3 (ru) 1977-10-25
CH620681A5 (en) 1980-12-15
DK92975A (en16) 1975-09-10
SE421919B (sv) 1982-02-08
ZA751394B (en) 1976-11-24
PL93699B1 (en16) 1977-06-30
ES440347A1 (es) 1977-06-01
ES440348A1 (es) 1977-06-01
FI63571B (fi) 1983-03-31
CH622017A5 (en) 1981-03-13
BG24814A4 (bg) 1978-05-12
NO750773L (en16) 1975-09-10
IL46760A0 (en) 1975-05-22
IE40945B1 (en) 1979-09-12
ES440349A1 (es) 1977-03-01
PH14127A (en) 1981-02-26
DK137188B (da) 1978-01-30
CS188221B2 (en) 1979-02-28
GB1496418A (en) 1977-12-30
BG24813A4 (bg) 1978-05-12
DE2411382C3 (de) 1979-09-06
ATA153875A (de) 1977-11-15
BE826440A (fr) 1975-09-08
AT344332B (de) 1978-07-10
DK137188C (da) 1978-07-03
CA1049511A (en) 1979-02-27
FI750652A7 (en16) 1975-09-10
JPS50123675A (en16) 1975-09-29
DE2411382A1 (de) 1975-09-18
IE40945L (en) 1975-09-09
NO141800B (no) 1980-02-04
HU177408B (en) 1981-10-28
RO70051A (ro) 1980-12-30
PL93700B1 (en16) 1977-06-30
FR2262984B1 (en16) 1978-07-28
JPS5827275B2 (ja) 1983-06-08
AU7894275A (en) 1976-09-16
NO141800C (no) 1980-06-04
FI63571C (fi) 1983-07-11
BG25087A3 (bg) 1978-07-12
ES440346A1 (es) 1977-03-01
DE2411382B2 (de) 1979-01-18
CH622015A5 (en) 1981-03-13
CH622016A5 (en) 1981-03-13
SE7502592L (en16) 1975-09-10
RO69617A (ro) 1980-08-15
SU588916A3 (ru) 1978-01-15
SU577982A3 (ru) 1977-10-25
ES440350A1 (es) 1977-03-16
NL7502724A (nl) 1975-09-11
CH620440A5 (en) 1980-11-28
CH612425A5 (en) 1979-07-31
CH622014A5 (en) 1981-03-13
CH620439A5 (en) 1980-11-28

Similar Documents

Publication Publication Date Title
PL93499B1 (en16)
PL99838B1 (pl) Sposob wytwarzania nowych 5,9 beta-dwupodstawionych 2-tetrahydrofurfurylo-6,7-benzomorfanow
CA3186645A1 (en) Antiplatelet drugs and uses thereof
PL92086B1 (en16)
SU873887A3 (ru) Способ получени производных имидазо/2,1-в/тиазолина или имидазо /2,1-в/тиазина или их кислотно-аддитивных солей,в виде смеси изомеров или отдельных изомеров
PL91560B1 (en16)
KR840001552B1 (ko) 시클로헥센 유도체의 제조방법
US4087532A (en) Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US4528289A (en) Corynantheine derivates, processes for their preparation, and their use
WO2021194623A1 (en) 8-substituted diaryl xanthines as dual a 2a-a 2b antagonists
PL84398B1 (en) 1-(2'-cyano-phenoxy)-2-hydroxy-3-ethylamino-propane and salts thereof[us3732277a]
US4977176A (en) Pilocarpine compounds which are used as pharmaceutical agents
PL135814B1 (en) Process for preparing novel bocyclic compounds
US4225602A (en) Tetrahydropyridine derivative useful for inhibiting blood platelet aggregation
PL106888B1 (pl) Sposob wytwarzania nowych amin pochodnych 2-fenylodwucyklooktanu i oktenu
PL84224B1 (en16)
US5055490A (en) Stereoisomers of benzonitrile derivatives, useful as cardiac arrhythmiac agents
PL103784B1 (pl) Sposob wytwarzania nowej pochodnej fenylopirydyloaminy
US4835174A (en) Pilocarpine derivatives
KR810000890B1 (ko) 2-테트라하이드로푸르푸릴-6,7-벤조모르판류의 제조방법
KR810000889B1 (ko) 2-테트라하이드로푸르푸릴-7,6-벤조모르판류의 제조방법
KR810000801B1 (ko) 2-테트라 하이드로 푸르푸릴-6,7-벤조모르판류의 제조방법
FI63399B (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 2'-hydroxi-2-(5-isoxazolylmetyl)-6,7-bensomorfaner och derassyraadditionssalter
KR830000813B1 (ko) 2-(2-알콕시에틸)-2'-하이드록시-6, 7-벤조모르판의 제조방법
PL144546B1 (en) Method of obtaining novel derivatives of azabicyclo /3.3.1/nonane