RO70051A - Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani - Google Patents

Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani

Info

Publication number
RO70051A
RO70051A RO7589654A RO8965475A RO70051A RO 70051 A RO70051 A RO 70051A RO 7589654 A RO7589654 A RO 7589654A RO 8965475 A RO8965475 A RO 8965475A RO 70051 A RO70051 A RO 70051A
Authority
RO
Romania
Prior art keywords
hydrofurfuril
benzomorphanes
tetra
preparation
Prior art date
Application number
RO7589654A
Other languages
English (en)
French (fr)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walher
Klaus Stockhaus
Original Assignee
Ch Boehringer Sohn,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ch Boehringer Sohn,De filed Critical Ch Boehringer Sohn,De
Publication of RO70051A publication Critical patent/RO70051A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RO7589654A 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani RO70051A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
RO70051A true RO70051A (ro) 1980-12-30

Family

ID=5909593

Family Applications (2)

Application Number Title Priority Date Filing Date
RO7589654A RO70051A (ro) 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani
RO7589653A RO69617A (ro) 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani

Family Applications After (1)

Application Number Title Priority Date Filing Date
RO7589653A RO69617A (ro) 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani

Country Status (25)

Country Link
JP (1) JPS5827275B2 (ro)
AT (1) AT344332B (ro)
BE (1) BE826440A (ro)
BG (3) BG24814A4 (ro)
CA (1) CA1049511A (ro)
CH (8) CH612425A5 (ro)
CS (1) CS188221B2 (ro)
DD (1) DD119236A5 (ro)
DE (1) DE2411382C3 (ro)
DK (1) DK137188C (ro)
ES (6) ES440345A1 (ro)
FI (1) FI63571C (ro)
FR (1) FR2262984B1 (ro)
GB (1) GB1496418A (ro)
HU (1) HU177408B (ro)
IE (1) IE40945B1 (ro)
IL (1) IL46760A (ro)
NL (1) NL7502724A (ro)
NO (1) NO141800C (ro)
PH (1) PH14127A (ro)
PL (3) PL93699B1 (ro)
RO (2) RO70051A (ro)
SE (1) SE421919B (ro)
SU (3) SU577982A3 (ro)
ZA (1) ZA751394B (ro)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JP3955093B2 (ja) * 1995-03-10 2007-08-08 フォトキュア エイエスエイ 光化学治療における光増感剤としての５−アミノレブリン酸のエステル
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ATE554078T1 (de) 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
CL2008003407A1 (es) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071236A1 (es) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
AR071609A1 (es) 2008-05-01 2010-06-30 Vitae Pharmaceuticals Inc Inhibidores ciclicos de 11(beta) -hidroxiesteroide deshidrogenasa 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
WO2010010157A2 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
CA2730499A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IE40945L (en) 1975-09-09
ES440346A1 (es) 1977-03-01
IE40945B1 (en) 1979-09-12
RO69617A (ro) 1980-08-15
FI63571B (fi) 1983-03-31
ES440348A1 (es) 1977-06-01
CH622016A5 (en) 1981-03-13
CH622015A5 (en) 1981-03-13
DD119236A5 (ro) 1976-04-12
AU7894275A (en) 1976-09-16
SU588916A3 (ru) 1978-01-15
IL46760A (en) 1978-12-17
ES440350A1 (es) 1977-03-16
BG24813A4 (en) 1978-05-12
NO750773L (ro) 1975-09-10
HU177408B (en) 1981-10-28
DK92975A (ro) 1975-09-10
DK137188B (da) 1978-01-30
CA1049511A (en) 1979-02-27
PL93699B1 (ro) 1977-06-30
CS188221B2 (en) 1979-02-28
CH622014A5 (en) 1981-03-13
FR2262984A1 (ro) 1975-10-03
SU577983A3 (ru) 1977-10-25
IL46760A0 (en) 1975-05-22
CH612425A5 (en) 1979-07-31
PL93499B1 (ro) 1977-05-30
BG25087A3 (en) 1978-07-12
DE2411382B2 (de) 1979-01-18
ES440347A1 (es) 1977-06-01
DK137188C (da) 1978-07-03
NO141800C (no) 1980-06-04
BG24814A4 (en) 1978-05-12
CH620681A5 (en) 1980-12-15
JPS5827275B2 (ja) 1983-06-08
AT344332B (de) 1978-07-10
CH620440A5 (en) 1980-11-28
NO141800B (no) 1980-02-04
FI63571C (fi) 1983-07-11
DE2411382C3 (de) 1979-09-06
ATA153875A (de) 1977-11-15
CH622017A5 (en) 1981-03-13
ZA751394B (en) 1976-11-24
BE826440A (fr) 1975-09-08
FR2262984B1 (ro) 1978-07-28
NL7502724A (nl) 1975-09-11
PL93700B1 (ro) 1977-06-30
SE7502592L (ro) 1975-09-10
ES440349A1 (es) 1977-03-01
SU577982A3 (ru) 1977-10-25
FI750652A (ro) 1975-09-10
JPS50123675A (ro) 1975-09-29
PH14127A (en) 1981-02-26
CH620439A5 (en) 1980-11-28
ES440345A1 (es) 1977-03-01
GB1496418A (en) 1977-12-30
SE421919B (sv) 1982-02-08
DE2411382A1 (de) 1975-09-18

Similar Documents

Publication Publication Date Title
RO72736A (ro) Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani-5,9-beta-disubstituiti
RO70051A (ro) Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani
RO68142A (ro) Procedeu pentru prepararea unor 4-fenilpiperidine
RO71766A (ro) Procedeu pentru prepararea hexahidrodibenzo-(b,d)-piranilor
RO63727A (fr) Procede pour la preparation des 4-oxo-2h-1,2-benzothiazine-3-carboxamides
RO65454A (ro) Procedeu pentru prepararea unor calcone substituite
RO65957A (fr) Procede pour la preparation des piperazinyle-quinazolines
RO63539A (fr) Procede pour la preparation des piperazinylquinoxalines
RO81766A (ro) Procedeu pentru prepararea unor fenilalchilamine
RO68145A (ro) Procedeu pentru prepararea unor 3,4-dihidro-2h-1,2-benzo-tiazincarboxamide
RO63749A (fr) Procede pour la preparation des 5-pyrazolones-1-substituees
RO66914A (ro) Procedeu pentru prepararea de pirido-benzodiazepinone
RO80170A (ro) Procedeu pentru prepararea 6-desoxitetraciclinelor
RO71806A (ro) Procedeu pentru prepararea unor aril-acetilene
RO64606A (fr) Procede pour la preparation des 6-methylergolines-8,8-disubstituees
RO63021A (fr) Procede pour la preparation des 3-fluorcephalosporines
RO64281A (fr) Procede pour la preparation des 6-methyle-8-methylergolines substituees
RO68008A (ro) Procedeu pentru prepararea de poli-n-alchil-iminoalani
RO69152A (ro) Procedeu pentru prepararea unor benzilamine
RO68749A (ro) Procedeu pentru prepararea 2-aminoimidazolilor
RO66020A (ro) Procedeu pentru prepararea unor 3-piperazinoizochinoline
RO72516A (ro) Procedeu pentru prepararea unor chinoxalin-1,4-dioxizi
BE824730A (fr) Procede pour la preparation de cyclopentandiones
RO64485A (fr) Procede pour la preparation des benzimidazol-1-carbonamides
RO64926A (fr) Procede pour la preparation des 4-oxo-2-imidazolidinilidenurees