ATA153875A - Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saureadditionssalzen - Google Patents

Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saureadditionssalzen

Info

Publication number
ATA153875A
ATA153875A AT153875A AT153875A ATA153875A AT A153875 A ATA153875 A AT A153875A AT 153875 A AT153875 A AT 153875A AT 153875 A AT153875 A AT 153875A AT A153875 A ATA153875 A AT A153875A
Authority
AT
Austria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
preparation
new
acid addition
Prior art date
Application number
AT153875A
Other languages
English (en)
Other versions
AT344332B (de
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ATA153875A publication Critical patent/ATA153875A/de
Application granted granted Critical
Publication of AT344332B publication Critical patent/AT344332B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT153875A 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen AT344332B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (2)

Publication Number Publication Date
ATA153875A true ATA153875A (de) 1977-11-15
AT344332B AT344332B (de) 1978-07-10

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT153875A AT344332B (de) 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen

Country Status (25)

Country Link
JP (1) JPS5827275B2 (de)
AT (1) AT344332B (de)
BE (1) BE826440A (de)
BG (3) BG25087A3 (de)
CA (1) CA1049511A (de)
CH (8) CH612425A5 (de)
CS (1) CS188221B2 (de)
DD (1) DD119236A5 (de)
DE (1) DE2411382C3 (de)
DK (1) DK137188C (de)
ES (6) ES440349A1 (de)
FI (1) FI63571C (de)
FR (1) FR2262984B1 (de)
GB (1) GB1496418A (de)
HU (1) HU177408B (de)
IE (1) IE40945B1 (de)
IL (1) IL46760A (de)
NL (1) NL7502724A (de)
NO (1) NO141800C (de)
PH (1) PH14127A (de)
PL (3) PL93699B1 (de)
RO (2) RO69617A (de)
SE (1) SE421919B (de)
SU (3) SU577982A3 (de)
ZA (1) ZA751394B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6034267A (en) * 1995-03-10 2000-03-07 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
WO2009017671A1 (en) 2007-07-26 2009-02-05 Vitae Pharmaceuticals, Inc. Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
CL2008003407A1 (es) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
EP2229368A1 (de) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclische harnstoffe als inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8138178B2 (en) 2008-05-01 2012-03-20 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
CA2723039A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
KR20110050459A (ko) 2008-07-25 2011-05-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
ZA751394B (en) 1976-11-24
SU588916A3 (ru) 1978-01-15
BE826440A (fr) 1975-09-08
GB1496418A (en) 1977-12-30
CH612425A5 (en) 1979-07-31
CH620681A5 (en) 1980-12-15
HU177408B (en) 1981-10-28
ES440346A1 (es) 1977-03-01
DD119236A5 (de) 1976-04-12
IL46760A0 (en) 1975-05-22
FI63571C (fi) 1983-07-11
FR2262984A1 (de) 1975-10-03
CA1049511A (en) 1979-02-27
CH622015A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
DE2411382B2 (de) 1979-01-18
SU577983A3 (ru) 1977-10-25
IL46760A (en) 1978-12-17
NO141800B (no) 1980-02-04
DK92975A (de) 1975-09-10
IE40945B1 (en) 1979-09-12
NO141800C (no) 1980-06-04
SE7502592L (de) 1975-09-10
CH620440A5 (en) 1980-11-28
NL7502724A (nl) 1975-09-11
ES440345A1 (es) 1977-03-01
SE421919B (sv) 1982-02-08
JPS5827275B2 (ja) 1983-06-08
PL93699B1 (de) 1977-06-30
PL93700B1 (de) 1977-06-30
AU7894275A (en) 1976-09-16
BG24814A4 (bg) 1978-05-12
PL93499B1 (de) 1977-05-30
IE40945L (en) 1975-09-09
DE2411382C3 (de) 1979-09-06
CH622016A5 (en) 1981-03-13
CS188221B2 (en) 1979-02-28
BG24813A4 (bg) 1978-05-12
DK137188B (da) 1978-01-30
DE2411382A1 (de) 1975-09-18
FR2262984B1 (de) 1978-07-28
SU577982A3 (ru) 1977-10-25
ES440348A1 (es) 1977-06-01
ES440349A1 (es) 1977-03-01
RO70051A (ro) 1980-12-30
PH14127A (en) 1981-02-26
ES440350A1 (es) 1977-03-16
CH622014A5 (en) 1981-03-13
BG25087A3 (bg) 1978-07-12
FI750652A7 (de) 1975-09-10
DK137188C (da) 1978-07-03
RO69617A (ro) 1980-08-15
ES440347A1 (es) 1977-06-01
JPS50123675A (de) 1975-09-29
CH620439A5 (en) 1980-11-28
NO750773L (de) 1975-09-10
FI63571B (fi) 1983-03-31
AT344332B (de) 1978-07-10

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee