GB1496418A - Benzomorphanes derivatives - Google Patents

Benzomorphanes derivatives

Info

Publication number
GB1496418A
GB1496418A GB9633/75A GB963375A GB1496418A GB 1496418 A GB1496418 A GB 1496418A GB 9633/75 A GB9633/75 A GB 9633/75A GB 963375 A GB963375 A GB 963375A GB 1496418 A GB1496418 A GB 1496418A
Authority
GB
United Kingdom
Prior art keywords
methyl
formula
action
denotes hydrogen
morphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9633/75A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG, Boehringer Ingelheim GmbH filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB1496418A publication Critical patent/GB1496418A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GB9633/75A 1974-03-09 1975-03-07 Benzomorphanes derivatives Expired GB1496418A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
GB1496418A true GB1496418A (en) 1977-12-30

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9633/75A Expired GB1496418A (en) 1974-03-09 1975-03-07 Benzomorphanes derivatives

Country Status (25)

Country Link
JP (1) JPS5827275B2 (de)
AT (1) AT344332B (de)
BE (1) BE826440A (de)
BG (3) BG25087A3 (de)
CA (1) CA1049511A (de)
CH (8) CH612425A5 (de)
CS (1) CS188221B2 (de)
DD (1) DD119236A5 (de)
DE (1) DE2411382C3 (de)
DK (1) DK137188C (de)
ES (6) ES440348A1 (de)
FI (1) FI63571C (de)
FR (1) FR2262984B1 (de)
GB (1) GB1496418A (de)
HU (1) HU177408B (de)
IE (1) IE40945B1 (de)
IL (1) IL46760A (de)
NL (1) NL7502724A (de)
NO (1) NO141800C (de)
PH (1) PH14127A (de)
PL (3) PL93499B1 (de)
RO (2) RO69617A (de)
SE (1) SE421919B (de)
SU (3) SU577982A3 (de)
ZA (1) ZA751394B (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU708076B2 (en) * 1995-03-10 1999-07-29 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7217736B2 (en) 2000-07-27 2007-05-15 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7247655B2 (en) 1995-03-10 2007-07-24 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
EP2183228B1 (de) 2007-07-26 2014-08-20 Vitae Pharmaceuticals, Inc. ZYKLISCHE 11ß-HYDROXYSTEROID-DEHYDROGENASE-1-HEMMER
WO2009063061A2 (en) 2007-11-16 2009-05-22 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
WO2009102460A2 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
CA2723039A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (de) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
CA2724214A1 (en) 2008-05-13 2009-11-19 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ590495A (en) 2008-07-25 2012-10-26 Vitae Pharmaceuticals Inc Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
US8933072B2 (en) 2010-06-16 2015-01-13 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU708076B2 (en) * 1995-03-10 1999-07-29 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7247655B2 (en) 1995-03-10 2007-07-24 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7287646B2 (en) 1995-03-10 2007-10-30 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7850008B2 (en) 1995-03-10 2010-12-14 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US8410172B2 (en) 1995-03-10 2013-04-02 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7217736B2 (en) 2000-07-27 2007-05-15 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7563819B1 (en) 2000-07-27 2009-07-21 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Also Published As

Publication number Publication date
CA1049511A (en) 1979-02-27
RO70051A (ro) 1980-12-30
BG24813A4 (en) 1978-05-12
CH612425A5 (en) 1979-07-31
DE2411382A1 (de) 1975-09-18
DK137188C (da) 1978-07-03
AU7894275A (en) 1976-09-16
CH622014A5 (en) 1981-03-13
DE2411382C3 (de) 1979-09-06
FI63571B (fi) 1983-03-31
ZA751394B (en) 1976-11-24
PL93499B1 (de) 1977-05-30
BG25087A3 (en) 1978-07-12
JPS50123675A (de) 1975-09-29
PL93700B1 (de) 1977-06-30
SE7502592L (de) 1975-09-10
DE2411382B2 (de) 1979-01-18
NO141800B (no) 1980-02-04
IE40945L (en) 1975-09-09
NL7502724A (nl) 1975-09-11
ES440349A1 (es) 1977-03-01
IL46760A (en) 1978-12-17
CH620681A5 (en) 1980-12-15
PL93699B1 (de) 1977-06-30
NO141800C (no) 1980-06-04
RO69617A (ro) 1980-08-15
CH620440A5 (en) 1980-11-28
ES440348A1 (es) 1977-06-01
AT344332B (de) 1978-07-10
CH622017A5 (en) 1981-03-13
ES440350A1 (es) 1977-03-16
FI750652A (de) 1975-09-10
ES440347A1 (es) 1977-06-01
CS188221B2 (en) 1979-02-28
ES440346A1 (es) 1977-03-01
NO750773L (de) 1975-09-10
PH14127A (en) 1981-02-26
DD119236A5 (de) 1976-04-12
IL46760A0 (en) 1975-05-22
BG24814A4 (en) 1978-05-12
SU577982A3 (ru) 1977-10-25
FI63571C (fi) 1983-07-11
ES440345A1 (es) 1977-03-01
DK92975A (de) 1975-09-10
SU588916A3 (ru) 1978-01-15
CH620439A5 (en) 1980-11-28
CH622015A5 (en) 1981-03-13
HU177408B (en) 1981-10-28
DK137188B (da) 1978-01-30
FR2262984B1 (de) 1978-07-28
JPS5827275B2 (ja) 1983-06-08
SE421919B (sv) 1982-02-08
CH622016A5 (en) 1981-03-13
IE40945B1 (en) 1979-09-12
SU577983A3 (ru) 1977-10-25
FR2262984A1 (de) 1975-10-03
ATA153875A (de) 1977-11-15
BE826440A (fr) 1975-09-08

Similar Documents

Publication Publication Date Title
GB1496418A (en) Benzomorphanes derivatives
PT83843A (en) Process for preparing prodrugs of rapamycin
ES382550A1 (es) Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino-tieno (3,2-d) pirimidinas.
GB1062714A (en) -ß-(4'-acyloxy-4'-piperidyl)-ketones
ES449099A1 (es) Procedimiento para preparar derivados de piperidina.
ES447495A1 (es) Un procedimiento de preparacion de derivados de tetrahidro- 4, 5, 6, 7-tieno-(3, 2-c)-piridina.
GB1314952A (en) 3,4,5-trialkoxy-benzoic acid derivatives and their uses
ES317454A1 (es) Procedimiento para la preparacion de amidas de derivados de acido lisergico.
GB925723A (en) Novel thebaine derivatives
ES474986A1 (es) Procedimiento para la preparacion de derivados de la isoqui-noleina
ES307982A1 (es) Procedimiento para la preparacion de nuevas amidas de acido ariloxiacetico.
ES484422A1 (es) Un procedimiento para la isomerizacion de un 2-ciano-3-aza- biciclo (3.1.0) hexano cis o trans
SE7706693L (sv) Sett att framstella hydrazinopyridazinderivat
ES403910A1 (es) Procedimiento para la preparacion de imidazo (4,5-b) piri- dina.
ES274910A1 (es) Procedimiento para la preparaciën de nuevos derivados de iminodibencilo
SE405113B (sv) Forfarande for framstellning av pyroglutamylforeningar med antidepressiv verkan
ES360858A1 (es) Procedimiento para la preparacion de nuevos derivados de tiazepina.
GB1482380A (en) Phenylbutazone derivatives
ES459866A1 (es) Procedimiento para preparar derivados del indol.
ES383107A1 (es) Procedimiento para la preparacion de nuevos derivados de dibenzociclopropapentaleno.
ES393259A1 (es) Un procedimiento para la preparacion de derivados esterifi-cados de piridilbenzopiranos.
JPS51125281A (en) A process for preparing indazole derivatives
ES373930A1 (es) Procedimiento para la preparacion de nuevos derivados de a-zepina.
ES320083A1 (es) Procedimiento de preparacion de los derivados de la difenilamina.
GR26414B (el) Μεθοδος δια την παρασκευην νεων ετεροκυκλικων ενωσεων.

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee