GB1482380A - Phenylbutazone derivatives - Google Patents

Phenylbutazone derivatives

Info

Publication number
GB1482380A
GB1482380A GB35252/75A GB3525275A GB1482380A GB 1482380 A GB1482380 A GB 1482380A GB 35252/75 A GB35252/75 A GB 35252/75A GB 3525275 A GB3525275 A GB 3525275A GB 1482380 A GB1482380 A GB 1482380A
Authority
GB
United Kingdom
Prior art keywords
phenylbutazone
compounds
heterocyclic radical
derivatives
nicotinic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB35252/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PLURIPHARM
Original Assignee
PLURIPHARM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PLURIPHARM filed Critical PLURIPHARM
Publication of GB1482380A publication Critical patent/GB1482380A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel phenylbutazone derivatives of the accompanying formula I, in which R represents an alkyl radical having 1 to 5 carbon atoms or a heterocyclic radical, preferably the heterocyclic radical of nicotinic or isonicotinic acid, are prepared by reaction of phenylbutazone with L- or D,L-proline whose N atom is protected by the -COR group. The compounds are distinguished by a good anti-inflammatory action, the undesired side effects being very low. The compounds can be used for medicaments for the treatment of rheumatic disorders. <IMAGE>
GB35252/75A 1974-08-26 1975-08-26 Phenylbutazone derivatives Expired GB1482380A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7429109A FR2282884A1 (en) 1974-08-26 1974-08-26 NEW DERIVATIVES OF PHENYLBUTAZONE

Publications (1)

Publication Number Publication Date
GB1482380A true GB1482380A (en) 1977-08-10

Family

ID=9142574

Family Applications (1)

Application Number Title Priority Date Filing Date
GB35252/75A Expired GB1482380A (en) 1974-08-26 1975-08-26 Phenylbutazone derivatives

Country Status (13)

Country Link
AT (1) AT343111B (en)
BE (1) BE832722A (en)
CH (1) CH615434A5 (en)
DE (1) DE2537590A1 (en)
DK (1) DK138495B (en)
FI (1) FI61893C (en)
FR (1) FR2282884A1 (en)
GB (1) GB1482380A (en)
IE (1) IE41788B1 (en)
LU (1) LU73250A1 (en)
NL (1) NL7509999A (en)
NO (1) NO142220C (en)
SE (1) SE421618B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1604045A (en) * 1977-06-01 1981-12-02 Sterwin Ag -(2-methyl-indol-3-yl)-acetic acid esters processes for its prepartion and pharmaceutical compositions incorporating the same

Also Published As

Publication number Publication date
IE41788B1 (en) 1980-03-26
CH615434A5 (en) 1980-01-31
NO142220C (en) 1980-07-16
SE421618B (en) 1982-01-18
NL7509999A (en) 1976-03-01
NO142220B (en) 1980-04-08
DK138495C (en) 1979-03-05
FI61893B (en) 1982-06-30
FR2282884B1 (en) 1978-07-21
IE41788L (en) 1976-02-26
ATA650175A (en) 1977-09-15
DK138495B (en) 1978-09-18
DE2537590A1 (en) 1976-03-11
FI752387A (en) 1976-02-27
BE832722A (en) 1976-02-25
DK381075A (en) 1976-02-27
AT343111B (en) 1978-05-10
NO752923L (en) 1976-02-27
SE7509449L (en) 1976-02-27
FI61893C (en) 1982-10-11
FR2282884A1 (en) 1976-03-26
LU73250A1 (en) 1977-01-07

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee