SE7502592L - - Google Patents

Info

Publication number
SE7502592L
SE7502592L SE7502592A SE7502592A SE7502592L SE 7502592 L SE7502592 L SE 7502592L SE 7502592 A SE7502592 A SE 7502592A SE 7502592 A SE7502592 A SE 7502592A SE 7502592 L SE7502592 L SE 7502592L
Authority
SE
Sweden
Prior art keywords
methyl
formula
action
denotes hydrogen
morphine
Prior art date
Application number
SE7502592A
Other languages
English (en)
Other versions
SE421919B (sv
Inventor
H Merz
A Langebein
G Walther
K Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of SE7502592L publication Critical patent/SE7502592L/xx
Publication of SE421919B publication Critical patent/SE421919B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7502592A 1974-03-09 1975-03-07 Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner SE421919B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (2)

Publication Number Publication Date
SE7502592L true SE7502592L (de) 1975-09-10
SE421919B SE421919B (sv) 1982-02-08

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7502592A SE421919B (sv) 1974-03-09 1975-03-07 Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner

Country Status (25)

Country Link
JP (1) JPS5827275B2 (de)
AT (1) AT344332B (de)
BE (1) BE826440A (de)
BG (3) BG24813A4 (de)
CA (1) CA1049511A (de)
CH (8) CH612425A5 (de)
CS (1) CS188221B2 (de)
DD (1) DD119236A5 (de)
DE (1) DE2411382C3 (de)
DK (1) DK137188C (de)
ES (6) ES440348A1 (de)
FI (1) FI63571C (de)
FR (1) FR2262984B1 (de)
GB (1) GB1496418A (de)
HU (1) HU177408B (de)
IE (1) IE40945B1 (de)
IL (1) IL46760A (de)
NL (1) NL7502724A (de)
NO (1) NO141800C (de)
PH (1) PH14127A (de)
PL (3) PL93499B1 (de)
RO (2) RO70051A (de)
SE (1) SE421919B (de)
SU (3) SU577982A3 (de)
ZA (1) ZA751394B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
ES2157424T3 (es) * 1995-03-10 2001-08-16 Photocure Asa Esteres de acido 5-aminolevulinico como agentes fotosensibilizantes en fotoquimioterapia.
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1のサイクリックインヒビター
US8859580B2 (en) 2007-11-16 2014-10-14 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体
EP2300461B1 (de) 2008-05-01 2013-04-17 Vitae Pharmaceuticals, Inc. Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
EP2291371B1 (de) 2008-05-01 2015-06-10 Vitae Pharmaceuticals, Inc. Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤
EP2288596B1 (de) 2008-05-13 2016-11-30 Boehringer Ingelheim International GmbH Alizyklische carboxylsäurederivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
WO2010010157A2 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
EP2687525B1 (de) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Cyclische inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 置換5、6及び7員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IL46760A0 (en) 1975-05-22
IE40945B1 (en) 1979-09-12
CH620440A5 (en) 1980-11-28
FR2262984B1 (de) 1978-07-28
FI63571C (fi) 1983-07-11
CH622014A5 (en) 1981-03-13
BG24814A4 (en) 1978-05-12
CH620681A5 (en) 1980-12-15
DD119236A5 (de) 1976-04-12
CS188221B2 (en) 1979-02-28
AT344332B (de) 1978-07-10
CH620439A5 (en) 1980-11-28
DE2411382A1 (de) 1975-09-18
NO750773L (de) 1975-09-10
BG25087A3 (en) 1978-07-12
ES440347A1 (es) 1977-06-01
SE421919B (sv) 1982-02-08
AU7894275A (en) 1976-09-16
PL93700B1 (de) 1977-06-30
JPS5827275B2 (ja) 1983-06-08
GB1496418A (en) 1977-12-30
JPS50123675A (de) 1975-09-29
ES440346A1 (es) 1977-03-01
SU577982A3 (ru) 1977-10-25
RO70051A (ro) 1980-12-30
ATA153875A (de) 1977-11-15
CH622017A5 (en) 1981-03-13
IL46760A (en) 1978-12-17
PH14127A (en) 1981-02-26
PL93499B1 (de) 1977-05-30
RO69617A (ro) 1980-08-15
CH622016A5 (en) 1981-03-13
DK92975A (de) 1975-09-10
DK137188C (da) 1978-07-03
CH622015A5 (en) 1981-03-13
ES440349A1 (es) 1977-03-01
CA1049511A (en) 1979-02-27
FR2262984A1 (de) 1975-10-03
NO141800C (no) 1980-06-04
NO141800B (no) 1980-02-04
HU177408B (en) 1981-10-28
ES440345A1 (es) 1977-03-01
ES440350A1 (es) 1977-03-16
SU577983A3 (ru) 1977-10-25
IE40945L (en) 1975-09-09
BE826440A (fr) 1975-09-08
FI750652A (de) 1975-09-10
DE2411382C3 (de) 1979-09-06
FI63571B (fi) 1983-03-31
DK137188B (da) 1978-01-30
SU588916A3 (ru) 1978-01-15
ES440348A1 (es) 1977-06-01
NL7502724A (nl) 1975-09-11
ZA751394B (en) 1976-11-24
PL93699B1 (de) 1977-06-30
BG24813A4 (en) 1978-05-12
CH612425A5 (en) 1979-07-31
DE2411382B2 (de) 1979-01-18

Similar Documents

Publication Publication Date Title
SE7502592L (de)
ES431514A1 (es) Procedimiento para la preparacion de 2 - (heteroaril-metil)-5,9 beta - dialcohil-6,7-benzomorfanos.
ES382550A1 (es) Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino-tieno (3,2-d) pirimidinas.
SE7709913L (sv) Sett att framstella penta peptider
ES449099A1 (es) Procedimiento para preparar derivados de piperidina.
ES447495A1 (es) Un procedimiento de preparacion de derivados de tetrahidro- 4, 5, 6, 7-tieno-(3, 2-c)-piridina.
GB1314952A (en) 3,4,5-trialkoxy-benzoic acid derivatives and their uses
ES317454A1 (es) Procedimiento para la preparacion de amidas de derivados de acido lisergico.
GB925723A (en) Novel thebaine derivatives
ES474985A1 (es) Procedimiento para la preparacion de derivados de la isoqui-noleina
ES307982A1 (es) Procedimiento para la preparacion de nuevas amidas de acido ariloxiacetico.
ES484422A1 (es) Un procedimiento para la isomerizacion de un 2-ciano-3-aza- biciclo (3.1.0) hexano cis o trans
SE7706693L (sv) Sett att framstella hydrazinopyridazinderivat
NL7505473A (nl) Werkwijze voor het bereiden van pyroglutamylver- bindingen met antidepressieve werking.
ES274910A1 (es) Procedimiento para la preparaciën de nuevos derivados de iminodibencilo
ES403910A1 (es) Procedimiento para la preparacion de imidazo (4,5-b) piri- dina.
ES360858A1 (es) Procedimiento para la preparacion de nuevos derivados de tiazepina.
ES459866A1 (es) Procedimiento para preparar derivados del indol.
ES393259A1 (es) Un procedimiento para la preparacion de derivados esterifi-cados de piridilbenzopiranos.
GB1482380A (en) Phenylbutazone derivatives
ES383107A1 (es) Procedimiento para la preparacion de nuevos derivados de dibenzociclopropapentaleno.
ES290275A2 (es) Procedimiento para preparar nuevos compuestos de la 6-metil y la 1,6-dimetil-er-golina ii
GR26414B (el) Μεθοδος δια την παρασκευην νεων ετεροκυκλικων ενωσεων.
ES373930A1 (es) Procedimiento para la preparacion de nuevos derivados de a-zepina.
GB1056936A (en) Novel pregnane compounds and processes for their preparation

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7502592-4

Effective date: 19900125

Format of ref document f/p: F