PL3674302T3 - 1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET - Google Patents

1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET

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Publication number
PL3674302T3
PL3674302T3 PL20156599.1T PL20156599T PL3674302T3 PL 3674302 T3 PL3674302 T3 PL 3674302T3 PL 20156599 T PL20156599 T PL 20156599T PL 3674302 T3 PL3674302 T3 PL 3674302T3
Authority
PL
Poland
Prior art keywords
pyridin
ones
pyrazolo
pyrrolo
inhibitors
Prior art date
Application number
PL20156599.1T
Other languages
English (en)
Inventor
Andrew P. Combs
Thomas P. Maduskuie Jr.
Nikoo Falahatpisheh
Original Assignee
Incyte Holdings Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53055117&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3674302(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Holdings Corporation filed Critical Incyte Holdings Corporation
Publication of PL3674302T3 publication Critical patent/PL3674302T3/pl

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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PL20156599.1T 2014-04-23 2015-04-22 1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET PL3674302T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461983289P 2014-04-23 2014-04-23

Publications (1)

Publication Number Publication Date
PL3674302T3 true PL3674302T3 (pl) 2023-07-24

Family

ID=53055117

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20156599.1T PL3674302T3 (pl) 2014-04-23 2015-04-22 1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET
PL15721085T PL3134403T3 (pl) 2014-04-23 2015-04-22 1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET

Family Applications After (1)

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PL15721085T PL3134403T3 (pl) 2014-04-23 2015-04-22 1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET

Country Status (38)

Country Link
US (8) US9540368B2 (pl)
EP (3) EP3674302B1 (pl)
JP (2) JP6572237B2 (pl)
KR (3) KR102430144B1 (pl)
CN (1) CN106414442B (pl)
AR (1) AR100160A1 (pl)
AU (3) AU2015249810B2 (pl)
BR (1) BR112016024626B1 (pl)
CA (1) CA2946731C (pl)
CL (1) CL2016002681A1 (pl)
CR (2) CR20200231A (pl)
CY (2) CY1122948T1 (pl)
DK (2) DK3674302T3 (pl)
EA (2) EA039678B1 (pl)
EC (1) ECSP16088983A (pl)
ES (2) ES2784846T3 (pl)
FI (1) FI3674302T3 (pl)
HR (2) HRP20230340T1 (pl)
HU (2) HUE061770T2 (pl)
IL (3) IL248415B (pl)
LT (2) LT3134403T (pl)
MA (1) MA39985B1 (pl)
ME (1) ME03763B (pl)
MX (2) MX376174B (pl)
MY (3) MY180775A (pl)
NZ (3) NZ763740A (pl)
PE (1) PE20170144A1 (pl)
PH (1) PH12016502115B1 (pl)
PL (2) PL3674302T3 (pl)
PT (2) PT3134403T (pl)
RS (2) RS64231B1 (pl)
SG (2) SG10201809353TA (pl)
SI (2) SI3674302T1 (pl)
SM (2) SMT202300154T1 (pl)
TW (2) TWI735002B (pl)
UA (1) UA119870C2 (pl)
WO (1) WO2015164480A1 (pl)
ZA (1) ZA202101718B (pl)

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ES2635560T3 (es) 2013-07-08 2017-10-04 Incyte Holdings Corporation Heterociclos tricíclicos como inhibidores de la proteína NET
US9315501B2 (en) 2013-11-26 2016-04-19 Incyte Corporation Bicyclic heterocycles as BET protein inhibitors
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WO2015095492A1 (en) 2013-12-19 2015-06-25 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
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WO2016044130A1 (en) 2014-09-15 2016-03-24 Incyte Corporation Tricyclic heterocycles for use as bet protein inhibitors
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AR104259A1 (es) 2015-04-15 2017-07-05 Celgene Quanticel Res Inc Inhibidores de bromodominio
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