PL363264A1 - Pochodne izoksazoliny jako środki przeciwdepresyjne - Google Patents

Pochodne izoksazoliny jako środki przeciwdepresyjne

Info

Publication number
PL363264A1
PL363264A1 PL02363264A PL36326402A PL363264A1 PL 363264 A1 PL363264 A1 PL 363264A1 PL 02363264 A PL02363264 A PL 02363264A PL 36326402 A PL36326402 A PL 36326402A PL 363264 A1 PL363264 A1 PL 363264A1
Authority
PL
Poland
Prior art keywords
depressants
isoxazoline derivatives
isoxazoline
derivatives
Prior art date
Application number
PL02363264A
Other languages
English (en)
Other versions
PL208593B1 (pl
Inventor
Jose Ignacio Andres-Gil
Francisco Javier Fernandez-Gadea
Manuel Jesus Alcazar-Vaca
Jose Maria Cid-Nunez
Joaquin Pastor-Fernandez
Antonius Adrianus Hendrikus Petrus Megens
Godelieve Irma Christine Maria Heylen
Xavier Jean Michel Langlois
Margaretha Henrica Maria Bakker
Thomas Horst Wolfgang Steckler
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of PL363264A1 publication Critical patent/PL363264A1/pl
Publication of PL208593B1 publication Critical patent/PL208593B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL363264A 2001-02-21 2002-02-13 Pochodne izoksazoliny, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie PL208593B1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05
PCT/EP2002/001567 WO2002066484A1 (en) 2001-02-21 2002-02-13 Isoxazoline derivatives as anti-depressants

Publications (2)

Publication Number Publication Date
PL363264A1 true PL363264A1 (pl) 2004-11-15
PL208593B1 PL208593B1 (pl) 2011-05-31

Family

ID=26076836

Family Applications (1)

Application Number Title Priority Date Filing Date
PL363264A PL208593B1 (pl) 2001-02-21 2002-02-13 Pochodne izoksazoliny, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie

Country Status (32)

Country Link
US (1) US7169786B2 (pl)
EP (1) EP1368358B1 (pl)
JP (1) JP3953424B2 (pl)
KR (1) KR100848898B1 (pl)
CN (1) CN100400540C (pl)
AR (1) AR035685A1 (pl)
AT (1) ATE337322T1 (pl)
AU (1) AU2002244717B2 (pl)
BG (1) BG107984A (pl)
BR (1) BR0207433A (pl)
CA (1) CA2437505C (pl)
CY (1) CY1106448T1 (pl)
CZ (1) CZ20032515A3 (pl)
DE (1) DE60214138T2 (pl)
DK (1) DK1368358T3 (pl)
EA (1) EA006747B1 (pl)
EE (1) EE200300398A (pl)
EG (1) EG23929A (pl)
ES (1) ES2271230T3 (pl)
HR (1) HRP20030647A2 (pl)
HU (1) HUP0303270A3 (pl)
IL (2) IL157470A0 (pl)
MX (1) MXPA03007432A (pl)
MY (1) MY137836A (pl)
NO (1) NO20033700L (pl)
NZ (1) NZ526741A (pl)
PL (1) PL208593B1 (pl)
PT (1) PT1368358E (pl)
SI (1) SI1368358T1 (pl)
SK (1) SK11612003A3 (pl)
TW (1) TWI257392B (pl)
WO (1) WO2002066484A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
KR20040093061A (ko) * 2002-04-02 2004-11-04 얀센 파마슈티카 엔.브이. 치환된 아미노 이속사졸린 유도체 및 항-우울제로서의그의 용도
TW200409777A (en) 2002-08-12 2004-06-16 Janssen Pharmaceutica Nv C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
DE60331160D1 (de) * 2002-08-15 2010-03-18 Janssen Pharmaceutica Nv Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva
EP1532155B1 (en) * 2002-08-21 2008-02-27 Janssen Pharmaceutica N.V. C6- AND C9-SUBSTITUTED CHROMENO[4,3-c]ISOXAZOLINE DERIVATIVES AND THEIR USE AS ANTI-DEPRESSANTS
WO2004078715A1 (ja) * 2003-03-07 2004-09-16 Astellas Pharma Inc. 2,6-ジ置換スチリルを有する含窒素へテロ環誘導体
CN103788089A (zh) 2003-09-17 2014-05-14 詹森药业有限公司 作为血清素受体调节剂的稠合杂环化合物
EP1944306A1 (en) * 2003-09-17 2008-07-16 Janssen Pharmaceutica, N.V. Fused heterocyclic compounds as serotonin receptor modulators
CA2585857A1 (en) * 2004-11-26 2006-06-01 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity
NZ579431A (en) * 2007-03-09 2012-04-27 Sanofi Aventis Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
MX2009013205A (es) * 2007-06-08 2010-04-09 Helicon Therapeutics Inc Derivados de pirazoloquinolina urea terapeuticos.
WO2009082268A2 (ru) 2007-12-21 2009-07-02 Alla Chem, Llc ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0361577B1 (en) * 1988-09-19 1993-05-05 Akzo N.V. Tetrahydronaphthalene and indane derivatives
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
PT892804E (pt) * 1996-04-12 2003-01-31 Janssen Pharmaceutica Nv Derivados de isoxazolidina
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
EP1119568B1 (en) * 1998-10-09 2004-02-18 Janssen Pharmaceutica N.V. 4,5-dihydro-isoxazole derivatives and their pharmaceutical use

Also Published As

Publication number Publication date
EP1368358B1 (en) 2006-08-23
SK11612003A3 (sk) 2004-04-06
CZ20032515A3 (cs) 2003-12-17
TWI257392B (en) 2006-07-01
ES2271230T3 (es) 2007-04-16
CN100400540C (zh) 2008-07-09
HK1065537A1 (zh) 2005-02-25
EA200300915A1 (ru) 2004-06-24
EA006747B1 (ru) 2006-04-28
NO20033700D0 (no) 2003-08-20
CN1492871A (zh) 2004-04-28
PL208593B1 (pl) 2011-05-31
EE200300398A (et) 2003-12-15
IL157470A0 (en) 2004-03-28
MXPA03007432A (es) 2003-11-18
DE60214138T2 (de) 2007-03-29
US20040122037A1 (en) 2004-06-24
PT1368358E (pt) 2007-01-31
NO20033700L (no) 2003-10-21
JP2004518748A (ja) 2004-06-24
KR100848898B1 (ko) 2008-07-29
EP1368358A1 (en) 2003-12-10
ATE337322T1 (de) 2006-09-15
MY137836A (en) 2009-03-31
AU2002244717B2 (en) 2007-07-19
EG23929A (en) 2008-01-14
KR20030076590A (ko) 2003-09-26
BG107984A (bg) 2004-09-30
SI1368358T1 (sl) 2007-02-28
NZ526741A (en) 2004-04-30
DE60214138D1 (de) 2006-10-05
HUP0303270A3 (en) 2007-03-28
US7169786B2 (en) 2007-01-30
CY1106448T1 (el) 2011-10-12
DK1368358T3 (da) 2007-01-02
IL157470A (en) 2008-07-08
JP3953424B2 (ja) 2007-08-08
HUP0303270A2 (hu) 2004-01-28
HRP20030647A2 (en) 2005-06-30
CA2437505C (en) 2010-02-09
WO2002066484A1 (en) 2002-08-29
BR0207433A (pt) 2004-06-01
AR035685A1 (es) 2004-06-23
CA2437505A1 (en) 2002-08-29

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