PT892804E - Derivados de isoxazolidina - Google Patents

Derivados de isoxazolidina

Info

Publication number
PT892804E
PT892804E PT97919344T PT97919344T PT892804E PT 892804 E PT892804 E PT 892804E PT 97919344 T PT97919344 T PT 97919344T PT 97919344 T PT97919344 T PT 97919344T PT 892804 E PT892804 E PT 892804E
Authority
PT
Portugal
Prior art keywords
6alkyl
zero
pct
independently
optionally substituted
Prior art date
Application number
PT97919344T
Other languages
English (en)
Inventor
Jose Ignacio Andres-Gil
Pedro Martinez-Jimenez
Francisco Fernandez-Gadea
Victor Karel Sipido
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT892804E publication Critical patent/PT892804E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT97919344T 1996-04-12 1997-04-09 Derivados de isoxazolidina PT892804E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96200991 1996-04-12

Publications (1)

Publication Number Publication Date
PT892804E true PT892804E (pt) 2003-01-31

Family

ID=8223869

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97919344T PT892804E (pt) 1996-04-12 1997-04-09 Derivados de isoxazolidina

Country Status (20)

Country Link
US (1) US6156747A (pt)
EP (1) EP0892804B1 (pt)
JP (1) JP4299884B2 (pt)
KR (1) KR100598724B1 (pt)
CN (1) CN1082963C (pt)
AT (1) ATE222911T1 (pt)
AU (1) AU716470B2 (pt)
DE (1) DE69714980T2 (pt)
DK (1) DK0892804T3 (pt)
ES (1) ES2182064T3 (pt)
HU (1) HU221608B (pt)
IL (1) IL123656A (pt)
MY (1) MY117456A (pt)
NO (1) NO310077B1 (pt)
NZ (1) NZ329954A (pt)
PL (1) PL186541B1 (pt)
PT (1) PT892804E (pt)
TW (1) TW514637B (pt)
WO (1) WO1997039001A1 (pt)
ZA (1) ZA973122B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO588297A0 (en) 1997-03-26 1997-04-24 Luminis Pty Limited Mediation in melatonin production
US20050148018A1 (en) 1999-10-07 2005-07-07 David Weiner Methods of identifying inverse agonists of the serotonin 2A receptor
UA77650C2 (en) 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
EE200300398A (et) * 2001-02-21 2003-12-15 Janssen Pharmaceutica N.V. Isoksasoliini derivaat, selle saamine ja kasutamine depresioonivastase ravimi valmistamiseks ning seda sisaldav ravimkompositsioon
EA013595B1 (ru) * 2005-01-27 2010-06-30 Янссен Фармацевтика Н.В. Гетероциклические, тетрациклические производные гидрофурана в качестве ингибиторов 5htв терапии расстройств цнс

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7414038A (nl) * 1974-10-28 1976-05-03 Akzo Nv Nieuwe tetracyclische pyrrolidino derivaten.
TW206227B (pt) * 1989-10-05 1993-05-21 Sankyo Co
WO1996014321A1 (en) * 1994-11-02 1996-05-17 Janssen Pharmaceutica N.V. Substituted tetracyclic oxazepine and thiazepine derivatives with 5-ht2 receptor affinity
US5552399A (en) * 1994-11-02 1996-09-03 Janssen Pharmaceutica N.V. Substituted tetracyclic azepine derivatives

Also Published As

Publication number Publication date
US6156747A (en) 2000-12-05
DE69714980T2 (de) 2003-04-10
EP0892804A1 (en) 1999-01-27
JP2000508328A (ja) 2000-07-04
TW514637B (en) 2002-12-21
ZA973122B (en) 1998-10-12
DE69714980D1 (de) 2002-10-02
PL326871A1 (en) 1998-10-26
CN1205010A (zh) 1999-01-13
WO1997039001A1 (en) 1997-10-23
JP4299884B2 (ja) 2009-07-22
NO310077B1 (no) 2001-05-14
AU2385297A (en) 1997-11-07
HU221608B (hu) 2002-11-28
IL123656A (en) 2001-09-13
ES2182064T3 (es) 2003-03-01
DK0892804T3 (da) 2002-12-02
IL123656A0 (en) 1998-10-30
ATE222911T1 (de) 2002-09-15
KR19990067515A (ko) 1999-08-25
AU716470B2 (en) 2000-02-24
NO981077L (no) 1998-10-12
NO981077D0 (no) 1998-03-11
NZ329954A (en) 1999-07-29
MY117456A (en) 2004-06-30
PL186541B1 (pl) 2004-01-30
KR100598724B1 (ko) 2006-10-25
EP0892804B1 (en) 2002-08-28
HUP9901875A3 (en) 2000-06-28
HUP9901875A2 (hu) 1999-09-28
CN1082963C (zh) 2002-04-17

Similar Documents

Publication Publication Date Title
DE69720709D1 (de) Substituierte tetracyclische tetrahydrofuranderivate
CA2305612A1 (en) Halogen substituted tetracyclic tetrahydrofuran derivatives
PT892804E (pt) Derivados de isoxazolidina
IL127177A (en) ANTIPYSYCHOTIC 5-(1, 3, 4, 4a, 5, 9b-HEXAHYDRO-PYRIDO (3, 4-b) INDOL-2-YLALKYL) PYRIMIDIN-4-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IL104498A0 (en) Pyrroloimidazolyl or imidazopyridinyl substituted 1h-benzimidazole derivatives,their preparation and pharmaceutical compositions containing them
CA2232195A1 (en) Isoxazolidine derivatives
ZA959216B (en) SUbstituted tetracyclic oxazepine and thiazepine derivatives
MX9703250A (es) Derivados tetraciclicos de oxazepina y tiazepina sustituidos con afinidad al receptor de 5-ht2.