PL2849736T3 - Kompozycje zawierające prekursor sulforafanu glukorafaninę, glukozydazę, kwas askorbinowy i ekstrakt lub proszek z ostropestu plamistego - Google Patents

Kompozycje zawierające prekursor sulforafanu glukorafaninę, glukozydazę, kwas askorbinowy i ekstrakt lub proszek z ostropestu plamistego

Info

Publication number
PL2849736T3
PL2849736T3 PL13812796T PL13812796T PL2849736T3 PL 2849736 T3 PL2849736 T3 PL 2849736T3 PL 13812796 T PL13812796 T PL 13812796T PL 13812796 T PL13812796 T PL 13812796T PL 2849736 T3 PL2849736 T3 PL 2849736T3
Authority
PL
Poland
Prior art keywords
glucosidase
compositions
powder
ascorbic acid
milk thistle
Prior art date
Application number
PL13812796T
Other languages
English (en)
Inventor
Brian CORNBLATT
Grace CORNBLATT
Anton BZHELYANSKY
Robert W. Henderson
Original Assignee
Nutramax Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49882601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2849736(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nutramax Laboratories, Inc. filed Critical Nutramax Laboratories, Inc.
Publication of PL2849736T3 publication Critical patent/PL2849736T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01147Thioglucosidase (3.2.1.147), i.e. myrosinase
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
PL13812796T 2012-07-05 2013-07-03 Kompozycje zawierające prekursor sulforafanu glukorafaninę, glukozydazę, kwas askorbinowy i ekstrakt lub proszek z ostropestu plamistego PL2849736T3 (pl)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261668374P 2012-07-05 2012-07-05
US201261668328P 2012-07-05 2012-07-05
US201261668342P 2012-07-05 2012-07-05
US201261668364P 2012-07-05 2012-07-05
US201261668396P 2012-07-05 2012-07-05
US201261668386P 2012-07-05 2012-07-05
US201361794417P 2013-03-15 2013-03-15
EP13812796.4A EP2849736B1 (en) 2012-07-05 2013-07-03 Compositions comprising the sulforaphane precursor glucoraphanin, a glucosidase, ascorbic acid and milk thistle extract or powder
PCT/US2013/049261 WO2014008361A2 (en) 2012-07-05 2013-07-03 Compositions comprising a sulforaphane or a sulforaphane precursor and milk thistle extract or powder

Publications (1)

Publication Number Publication Date
PL2849736T3 true PL2849736T3 (pl) 2019-06-28

Family

ID=49882601

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18182247T PL3409280T3 (pl) 2012-07-05 2013-07-03 Kompozycje zawierające sulforafan i wyciąg lub proszek z ostropestu plamistego
PL13812796T PL2849736T3 (pl) 2012-07-05 2013-07-03 Kompozycje zawierające prekursor sulforafanu glukorafaninę, glukozydazę, kwas askorbinowy i ekstrakt lub proszek z ostropestu plamistego

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL18182247T PL3409280T3 (pl) 2012-07-05 2013-07-03 Kompozycje zawierające sulforafan i wyciąg lub proszek z ostropestu plamistego

Country Status (11)

Country Link
US (14) US20150174093A1 (pl)
EP (5) EP3821895A1 (pl)
JP (10) JP6548573B2 (pl)
CN (2) CN108355136B (pl)
AU (9) AU2013286721B2 (pl)
CA (5) CA2877329C (pl)
ES (3) ES2877326T3 (pl)
PL (2) PL3409280T3 (pl)
RU (2) RU2666953C2 (pl)
TW (6) TW201402128A (pl)
WO (4) WO2014008366A2 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10869853B2 (en) * 2011-10-31 2020-12-22 The Johns Hopkins University Compositions and methods for treating autism spectrum disorders
PL3409280T3 (pl) 2012-07-05 2021-10-18 Nutramax Laboratories, Inc. Kompozycje zawierające sulforafan i wyciąg lub proszek z ostropestu plamistego
CN105377252A (zh) 2013-03-14 2016-03-02 佛罗里达大学研究基金会 利用天然化合物和/或饮食调控癌症
US20140275235A1 (en) * 2013-03-15 2014-09-18 Loic Pierre Deleyrolle Treatment of Proliferative Disorders
EP2968990A4 (en) * 2013-03-15 2016-08-24 Nutramax Lab Inc COMPOSITIONS COMPRISING SULFORAPHANE OR SULFORAPHANE PRECURSOR AND PHYTOSTEROL OR PHYTOSTANOL
KR101515573B1 (ko) * 2014-11-07 2015-04-28 주식회사 파미니티 뉴그린 추출물을 유효성분으로 함유하는 해독용 조성물
BR112017012648B1 (pt) 2014-12-22 2020-12-08 Unilever N.V composição oral ou tópica e uso de um agonista de fator nuclear eritróide 2 relacionado ao fator 2 e um agonista do receptor hepático x como agentes ativos em uma composição oral ou tópica para beneficiar o crescimento da fibra capilar e/ou induzir o elemento de resposta antioxidante (are)
JP2018513123A (ja) 2015-03-12 2018-05-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Rorガンマ阻害剤を用いてがんを治療するための方法
US11020372B2 (en) 2015-03-24 2021-06-01 University Of Florida Research Foundation, Incorporated Dietary and natural product management of negative side effects of cancer treatment
ES2818179T3 (es) 2015-06-26 2021-04-09 Plant Bioscience Ltd Glucorafanina para uso en el tratamiento y/o prevención de la diabetes mellitus
KR20180014194A (ko) * 2015-06-26 2018-02-07 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 천연 화합물 및/또는 식단을 사용하는 염증의 치료 방법
WO2017013239A1 (en) * 2015-07-22 2017-01-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Nrf2 activators for the treatment of mycobacterial infections
EP3123874B1 (en) * 2015-07-28 2018-05-02 Fundacíon Tecnalia Research & Innovation Formulations comprising glucosinolates and myrosinase
GB201605013D0 (en) * 2016-03-24 2016-05-11 Inst Of Food Res S-methylcysteine sulfoxide for prostate cancer treatment
US11344575B2 (en) * 2016-08-15 2022-05-31 Summit Innovation Labs, LLC Vascular calcification prevention and treatment
US11357250B2 (en) 2016-08-15 2022-06-14 Summit Innovation Labs LLC Treatment and prevention of diabetes and obesity
US10925304B2 (en) * 2016-12-28 2021-02-23 Productive Aging Laboratory, Co., Ltd. Method for treating chronic fatigue syndrome, idiopathic chronic fatigue, and fibromyalgia
JP7057070B2 (ja) 2017-06-21 2022-04-19 カゴメ株式会社 粉末食品、及びその製造方法、並びに粉末食品のミロシナーゼ活性促進方法
CA3077235A1 (en) * 2017-09-28 2019-04-04 Commonwealth Scientific And Industrial Research Organisation Isothiocyanate containing brassicaceae products and method of preparation thereof
EP3762005A4 (en) * 2018-03-05 2022-03-30 Laila Nutraceuticals SYNERGIC HERBAL COMPOSITIONS FOR THE TREATMENT OF OBESITY AND OVERWEIGHT
CN116474079A (zh) * 2019-05-08 2023-07-25 深圳福山生物科技有限公司 包含萝卜硫苷的组合物及其用途
WO2022047212A1 (en) * 2020-08-27 2022-03-03 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating neurodegenerative disorders
US11801273B2 (en) 2020-12-23 2023-10-31 Church & Dwight Co., Inc. Compositions and methods to increase production of isothiocyanates
CN112574161A (zh) * 2021-01-19 2021-03-30 江苏德和生物科技有限公司 一种富含egc的非酯型茶多酚的制备方法
JP7288474B2 (ja) 2021-03-10 2023-06-07 プライムプラネットエナジー&ソリューションズ株式会社 非水電解質二次電池の製造方法、および負極活物質
WO2022251524A1 (en) 2021-05-26 2022-12-01 Nutramax Laboratories, Inc. Compositions comprising sulforaphane or a sulforaphane precursor and moringa plant components
US20230364133A1 (en) * 2022-05-10 2023-11-16 Melaleuca, Inc. Dietary supplement compositions
WO2024064264A2 (en) * 2022-09-21 2024-03-28 Lile Method Research, Llc Compositions and methods for increasing glutathione levels

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3442639A1 (de) 1984-11-22 1986-05-22 Dr. Madaus & Co, 5000 Köln Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten
US5032401A (en) * 1989-06-15 1991-07-16 Alpha Beta Technology Glucan drug delivery system and adjuvant
US5223491A (en) 1989-11-09 1993-06-29 Donzis Byron A Method for revitalizing skin by applying topically water insoluble glucan
US5411986A (en) 1993-03-12 1995-05-02 The Johns Hopkins University Chemoprotective isothiocyanates
JPH07252148A (ja) * 1994-10-08 1995-10-03 Masahiro Nagahama 糖尿病治療薬
US5576015A (en) 1995-03-02 1996-11-19 Donzis; Byron A. Substantially purified beta (1,3) finely ground yeast cell wall glucan composition with dermatological and nutritional uses
US5725895B1 (en) 1995-09-15 2000-10-10 Hopkins J School Of Medicine Method of preparing food product from cruciferous seeds
US5686108A (en) * 1995-09-27 1997-11-11 Amway Corporation Brassica vegetable supplement and process for manufacture
JP3041232B2 (ja) 1995-11-16 2000-05-15 日本ケミカルリサーチ株式会社 癌転移抑制剤
JP2918834B2 (ja) 1995-12-25 1999-07-12 美穂 田中 シイタケエキス粉末の製造法
JP2859843B2 (ja) 1996-03-08 1999-02-24 株式会社雪国まいたけ マイタケから抽出した抗腫瘍物質
US6242018B1 (en) 1997-04-11 2001-06-05 Johns Hopkins School Of Medicine Cancer Chemoprotective food products
WO1999043336A1 (en) 1998-02-27 1999-09-02 Nutramax Laboratories, Inc. L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage
US20010000472A1 (en) 1998-02-27 2001-04-26 Nutramax Laboratories, Inc. L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage
US6521818B1 (en) 1998-07-01 2003-02-18 John Hopkins School Of Medicine Development of novel highly chemoprotectant crucifer germplasm
WO2000007607A1 (en) * 1998-08-04 2000-02-17 Kosbab, John, V. Nutrient and therapeutic compositions for the treatment of cancer
JP4308350B2 (ja) 1998-11-27 2009-08-05 小林製薬株式会社 シイタケ菌糸体抽出物を含有するlak活性スクリーニング物質およびそれを用いたlak活性スクリーニング法
US20030091518A1 (en) 1999-12-20 2003-05-15 Gilles Pauly Cosmetic and/or pharmaceutical preparations
WO2001054673A1 (en) 2000-01-31 2001-08-02 The University Of British Columbia Method for preparing and administering medicinal plant material
US6511675B2 (en) * 2000-06-12 2003-01-28 Access Business Group International, Llc Composition and method for correcting a dietary phytochemical deficiency
CN100522154C (zh) * 2000-08-21 2009-08-05 杰德W·费伊 异硫氰酸酯类化合物在制备治疗螺杆菌感染的药物中的用途
JP3504612B2 (ja) 2000-12-28 2004-03-08 株式会社東洋新薬 栄養補助食品
US6582723B2 (en) 2001-05-03 2003-06-24 Wayne F. Gorsek Cancer immune composition for prevention and treatment of individuals
US8017160B2 (en) * 2003-08-15 2011-09-13 Russell Jaffe Enhancement of magnesium uptake in mammals
JP2005073508A (ja) 2003-08-28 2005-03-24 Asahi Denka Kogyo Kk 食用または薬用植物を含有する飲料
ITMI20040696A1 (it) 2004-04-08 2004-07-08 Aboca S P A Composizioni per tisane arricchite con estratti secchi vegetali
JP4126053B2 (ja) * 2004-05-06 2008-07-30 堯 近藤 鹿角霊芝を含有した健康食品の製造方法
WO2005107496A1 (ja) 2004-05-06 2005-11-17 Maruasaen Corporation 生キノコエキス製造方法、エキス及びエキス配合物
RU2292899C2 (ru) 2004-06-29 2007-02-10 Дмитрий Николаевич Мясников Средство и способ профилактики и уменьшения неблагоприятных проявлений острой алкогольной интоксикации (варианты) и способ получения средства
US20060264497A1 (en) * 2005-03-28 2006-11-23 Zeligs Michael A Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health
EP1709969A1 (en) 2005-04-07 2006-10-11 Praktijkonderzoek Plant en Omgeving B.V. Health promoting dairy and food products containing mushroom glucan produced through fermentation of Grifola frondosa
KR100661032B1 (ko) * 2005-04-19 2006-12-22 주식회사한국야쿠르트 간 기능 개선, 혈중 알코올 감소 및 항산화에 유효한조성물
NZ563852A (en) * 2005-04-29 2011-07-29 Univ Johns Hopkins Methods of supressing UV light-induced skin carcinogenesis
US8124135B2 (en) 2005-05-24 2012-02-28 Vdf Futureceuticals, Inc. Compositions and methods for reduction of LDL oxidation
US7887852B2 (en) * 2005-06-03 2011-02-15 Soft Gel Technologies, Inc. Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
DE102005033616A1 (de) * 2005-07-19 2007-01-25 Biopro Ag Biological Products Verfahren zur Herstellung von Extrakten aus Brassica-Arten und ihre Verwendung
US20070021376A1 (en) * 2005-07-21 2007-01-25 Suracell, Inc. Supplement composition and method of use in enhancement of methylation process
US7597910B2 (en) 2005-08-20 2009-10-06 Slgm Medical Research Institute Compositions and methods for treating prostate disorders
RU2319494C2 (ru) * 2005-11-11 2008-03-20 РАНХЕЛЬ Хосе Анхель ОЛАЛДЕ Синергетическая композиция растительного происхождения (варианты), способ лечения заболеваний с ее использованием
US8323644B2 (en) 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
MY166532A (en) * 2006-02-10 2018-07-10 Mannatech Inc All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization
JP2007320947A (ja) * 2006-05-30 2007-12-13 Shonan Institute For Medical & Preventive Science 血糖値上昇抑制剤
JP4677033B2 (ja) 2006-06-02 2011-04-27 株式会社ハイマート マイタケ抽出物及びこれを含む皮脂産生を促進するための組成物
WO2008002175A1 (fr) * 2006-06-29 2008-01-03 Vulf Abramovich Laskin Régime hebdomadaire destiné aux patients oncologiques et aux personnes ayant une durée de vie remarquablement longue
US7803605B2 (en) 2006-07-14 2010-09-28 National Institute Of Advanced Industrial Science And Technology Breeding method for yeast, yeast and a production method for glycoprotein or beta-glucan
KR20080030722A (ko) 2006-10-02 2008-04-07 신현길 브로콜리가루가 첨가된 빵의 제조방법
WO2008115583A1 (en) * 2007-03-21 2008-09-25 John Mini Herbal treatments
US20080254055A1 (en) 2007-04-11 2008-10-16 John Erich Oblong Compositions for Regulation of Hair Growth
US20080311192A1 (en) * 2007-06-12 2008-12-18 Kraft Foods Holdings, Inc. Enteric-Coated Glucosinolates And Beta-Thioglucosidases
WO2009008006A2 (en) 2007-07-06 2009-01-15 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
CZ305673B6 (cs) 2007-08-02 2016-02-03 Irel, Spol. S R. O. Mechanicky upravený plod ostropestřce mariánského a způsob jeho úpravy
ES2325291B1 (es) 2007-10-04 2010-04-22 Madaus S A "uso de un extracto de silybum marianum"
EP2205237A1 (en) 2007-10-16 2010-07-14 Johns Hopkins University Methods for protecting the skin from radiation insults
WO2009063885A1 (ja) 2007-11-13 2009-05-22 Heimat Co., Ltd. マイタケ抽出物及びこれを含むヒアルロン酸(ヒアルロナン)産生を促進するための組成物
ITMI20080172A1 (it) * 2008-02-05 2009-08-06 Bios Line Spa Formulazioni orali per la protezione delle vie respiratorie con particolare riferimento ai fenomeni infiammatori e neoplastici
US20090252758A1 (en) * 2008-04-07 2009-10-08 Mazed Mohammad A Nutritional supplement for the prevention of cardiovascular disease, alzheimer's disease, diabetes, and regulation and reduction of blood sugar and insulin resistance
US7923044B2 (en) * 2008-07-15 2011-04-12 Paradise Herbs & Essentials, Inc. Composition for high-ORAC value dietary supplement
KR20100016876A (ko) * 2008-08-05 2010-02-16 오춘근 다이어트 및 당뇨에 유용한 기능성 혼합곡물
EP2213280A1 (en) 2009-01-30 2010-08-04 DSM IP Assets B.V. Formulations comprising glucosinolate and myrosinase
CN101514174B (zh) * 2009-02-24 2011-11-02 黑龙江八一农垦大学 一种从西兰花芽苗菜中提取多功能莱菔硫烷的方法
US8828953B2 (en) * 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
JP2010259424A (ja) * 2009-05-11 2010-11-18 Hisako Arai 簡単に摂取できる副食の調理法。
WO2011003045A1 (en) * 2009-07-01 2011-01-06 Magceutics, Inc. Slow release magnesium composition and uses thereof
WO2011060585A1 (zh) * 2009-11-20 2011-05-26 天津天狮生物发展有限公司 含有五色果蔬精华的咀嚼片剂及其制备方法
WO2011076154A1 (en) 2009-12-22 2011-06-30 Irel, Spol. S R.O. Feed supplement based on milk thistle, method of its production and its use
KR101079643B1 (ko) 2010-01-12 2011-11-04 이현재 신장 기능 강화용 식품 조성물 및 그 제조방법
WO2011099665A1 (ko) 2010-02-12 2011-08-18 주식회사 케이씨아이 천연 원료 추출물을 포함하는 항균 조성물, 복합 천연 방부제 및 이들의 제조방법
US20110206721A1 (en) * 2010-02-19 2011-08-25 Vijaya Nair Fermented soy nutritional supplements including mushroom components
US20120021079A1 (en) 2010-02-23 2012-01-26 Brett Justin West Garcinia Mangostana L. and Iridoid Based Formulations
US20110262595A1 (en) 2010-04-21 2011-10-27 Naturalife Asia Co., Ltd. Antioxidant nutritional supplement
US20110287109A1 (en) * 2010-05-24 2011-11-24 Max International, Llc Compositions And Beverages Comprising Nutrients, Vitamins, Sugars, Cysteine, And/Or Sugar-Cysteine Products
DE102010022587A1 (de) * 2010-05-28 2011-12-01 Wilfried Rühle Magensaftresistente Zusammensetzung zur oralen Einnahme von pflanzenbasierten Komponenten zur Prävention von Darmkrebs
CN102450534A (zh) * 2010-10-26 2012-05-16 宁波海逸生物科技有限公司 一种增强免疫力功能的西灵胶囊配方
ES2382299B1 (es) 2010-11-11 2013-05-07 Consejo Superior De Investigaciones Científicas (Csic) Polvo vegetal para alimentación y protección vegetal y métodos de preparación.
NZ589578A (en) * 2010-11-29 2013-03-28 Comvita Ltd Cancer Chemoprotective Product including glucosinolate and myrosinase
CN102526455A (zh) 2010-12-16 2012-07-04 天津中敖生物科技有限公司 具有清肺化痰功能的家畜用中药组合物及其制备方法
CN103458921B (zh) * 2011-02-22 2016-05-11 考迪尔种子公司 喷雾干燥的黑芥子酶和用于生产异硫氰酸酯的用途
WO2012122295A2 (en) * 2011-03-07 2012-09-13 Ned Biosystems, Inc. Treatment for pancreatic adenocarcinoma and other cancers of epithelial origin
US20130045273A1 (en) * 2011-08-19 2013-02-21 John Cuomo Methods for using nutritional supplements containing lipoic acids and sulfur containing compounds
CN102526445B (zh) * 2011-11-07 2013-12-11 宁波海逸生物科技有限公司 一种增强免疫力、缓解体力疲劳、抗肿瘤功能的保健药物配方
PL3409280T3 (pl) * 2012-07-05 2021-10-18 Nutramax Laboratories, Inc. Kompozycje zawierające sulforafan i wyciąg lub proszek z ostropestu plamistego

Also Published As

Publication number Publication date
EP2849737A2 (en) 2015-03-25
JP7232806B2 (ja) 2023-03-03
WO2014008361A3 (en) 2014-02-20
EP3409280A1 (en) 2018-12-05
WO2014008361A2 (en) 2014-01-09
JP7109132B2 (ja) 2022-07-29
CA2877356A1 (en) 2014-01-09
CN108355136A (zh) 2018-08-03
AU2013286721B2 (en) 2018-04-26
US10688158B2 (en) 2020-06-23
TW201402128A (zh) 2014-01-16
US20210008176A1 (en) 2021-01-14
CA3112680A1 (en) 2014-01-09
ES2700223T3 (es) 2019-02-14
CN104427981B (zh) 2018-05-25
US20150110872A1 (en) 2015-04-23
WO2014008341A2 (en) 2014-01-09
WO2014008366A3 (en) 2014-03-13
AU2022203801A1 (en) 2022-06-23
US11654186B2 (en) 2023-05-23
US20200261553A1 (en) 2020-08-20
CN104427981A (zh) 2015-03-18
WO2014008353A2 (en) 2014-01-09
RU2015103498A (ru) 2016-08-27
WO2014008341A3 (en) 2014-02-27
US11224639B2 (en) 2022-01-18
US20200101143A1 (en) 2020-04-02
US12064471B2 (en) 2024-08-20
EP3821895A1 (en) 2021-05-19
US20150118304A1 (en) 2015-04-30
RU2666953C2 (ru) 2018-09-13
RU2018130094A3 (pl) 2022-04-19
TWI637745B (zh) 2018-10-11
AU2013286713A1 (en) 2015-01-22
CA2877338C (en) 2022-10-11
CA2877338A1 (en) 2014-01-09
ES2755757T3 (es) 2020-04-23
US20210169997A1 (en) 2021-06-10
TW201402131A (zh) 2014-01-16
RU2018130094A (ru) 2018-10-04
US20150174213A1 (en) 2015-06-25
AU2013286721A1 (en) 2015-01-22
JP6548573B2 (ja) 2019-07-24
US20150174093A1 (en) 2015-06-25
JP2022059053A (ja) 2022-04-12
CN108355136B (zh) 2021-12-07
PL3409280T3 (pl) 2021-10-18
TWI606830B (zh) 2017-12-01
US9421183B2 (en) 2016-08-23
JP2024023619A (ja) 2024-02-21
CA2877356C (en) 2021-05-11
US20150118305A1 (en) 2015-04-30
AU2020223773A1 (en) 2020-09-17
JP2021001229A (ja) 2021-01-07
AU2020217440A1 (en) 2020-09-03
AU2018204604B2 (en) 2020-06-04
EP2849737B1 (en) 2019-09-11
EP3666277A1 (en) 2020-06-17
CA3112680C (en) 2023-07-25
JP2015522039A (ja) 2015-08-03
CA2877393A1 (en) 2014-01-09
AU2018204604C1 (en) 2020-11-19
AU2018204283B2 (en) 2020-07-09
RU2680387C2 (ru) 2019-02-20
JP7068383B2 (ja) 2022-05-16
TW201402130A (zh) 2014-01-16
JP2022137226A (ja) 2022-09-21
RU2015103499A (ru) 2016-08-27
JP6777366B2 (ja) 2020-10-28
CA2877329A1 (en) 2014-01-09
ES2877326T3 (es) 2021-11-16
JP2021038258A (ja) 2021-03-11
AU2020217440B2 (en) 2022-09-08
TWI580425B (zh) 2017-05-01
JP6436443B2 (ja) 2018-12-12
US20150147352A1 (en) 2015-05-28
AU2018204604A1 (en) 2018-07-12
EP2849736A2 (en) 2015-03-25
US10583178B2 (en) 2020-03-10
TW201717964A (zh) 2017-06-01
EP2849736B1 (en) 2018-09-05
US10960057B2 (en) 2021-03-30
JP2020128416A (ja) 2020-08-27
CA2877329C (en) 2020-01-07
CA2877393C (en) 2020-01-07
US20150196525A1 (en) 2015-07-16
TW201618791A (zh) 2016-06-01
US20160354448A1 (en) 2016-12-08
EP3409280B1 (en) 2021-04-14
EP2849737A4 (en) 2016-07-13
US20180200344A9 (en) 2018-07-19
AU2020223773B2 (en) 2023-04-27
WO2014008366A2 (en) 2014-01-09
AU2013286713B2 (en) 2018-04-05
JP2015523366A (ja) 2015-08-13
AU2018204283A1 (en) 2018-07-05
EP2849736A4 (en) 2016-07-13
AU2024205248A1 (en) 2024-08-22
US20220118062A1 (en) 2022-04-21
JP2019014763A (ja) 2019-01-31
JP2019023245A (ja) 2019-02-14
JP7458443B2 (ja) 2024-03-29
TW201402129A (zh) 2014-01-16
US20150118306A1 (en) 2015-04-30
WO2014008353A3 (en) 2014-03-06
AU2023208131A1 (en) 2023-08-17

Similar Documents

Publication Publication Date Title
PL2849736T3 (pl) Kompozycje zawierające prekursor sulforafanu glukorafaninę, glukozydazę, kwas askorbinowy i ekstrakt lub proszek z ostropestu plamistego
HK1209157A1 (en) Extraction, preparation, and application of plant micro-ribonucleic acid
HK1209599A1 (en) Products including capsules, uses and preparation thereof
EP2841138A4 (en) AEROSOL LABELING SYSTEMS, COMPOSITIONS AND METHOD
SG11201502567TA (en) Sintering powder
PL2827845T3 (pl) Kompozycje zawierające substancję dostarczającą i ich wytwarzanie
IL237839A0 (en) History of hydropyrrolopyrrole, their preparation and pharmaceutical preparations containing them
IL235414A (en) The history of pyrolotriazinone, their preparation and their pharmaceutical preparations
HK1206209A1 (en) Tobacco extract, preparation thereof
IL225824A0 (en) History of quinoxaline, their preparation and pharmaceutical preparations containing them
HRP20190489T1 (hr) Pripravci koji sadrže sredstvo za unošenje i njihova priprava
IL238060B (en) 2-aminopyridine derivatives, their preparation and pharmaceutical compositions containing them
IL233602A0 (en) History of benzamide, their preparation and pharmaceutical preparations containing them
EP2873701A4 (en) ORGANIC-INORGANIC COMPLEX, AND COMPOSITION FOR THE FORMATION OF SAID COMPLEX
IL233825A (en) H1-indazole-3-carboxamide compounds, preparations containing them and their use in the preparation of medicines
IL235955A0 (en) The history of benzothiophene, their preparation and pharmaceutical preparations containing them
EP2857421A4 (en) CELLULOSE POWDER
EP2924042A4 (en) BIS-BETA-CARBOLINE COMPOUND AND METHOD OF MANUFACTURING, PHARMACEUTICAL COMPOSITION AND USE THEREOF
HK1221162A1 (zh) 提取物和含有該提取物的製劑
HK1213221A1 (zh) 銀粉
HUE052328T2 (hu) Feijoa gyümölcs kivonat
IL238826A0 (en) History of imidazole - piperidinyl, their preparation and pharmaceutical preparations containing them
EP2844661A4 (en) FUSIONED HETEROCYCLE MORPHINANES, THEIR USE AND PREPARATION THEREOF
EP2837632A4 (en) COMPOUND JK12A AND ITS PREPARATION
EP2874283A4 (en) PROVISIONAL TERMINAL TERMINAL STRUCTURE AND TIMERS WITH PROVISIONAL TERMINAL TERMINAL STRUCTURE