PL2766682T3 - Sposób, linia technologiczna i wykorzystanie linii technologicznej do wytwarzania cząstek liofilizowanych - Google Patents

Sposób, linia technologiczna i wykorzystanie linii technologicznej do wytwarzania cząstek liofilizowanych

Info

Publication number
PL2766682T3
PL2766682T3 PL12769026T PL12769026T PL2766682T3 PL 2766682 T3 PL2766682 T3 PL 2766682T3 PL 12769026 T PL12769026 T PL 12769026T PL 12769026 T PL12769026 T PL 12769026T PL 2766682 T3 PL2766682 T3 PL 2766682T3
Authority
PL
Poland
Prior art keywords
process line
freeze
production
dried particles
line
Prior art date
Application number
PL12769026T
Other languages
English (en)
Inventor
Bernhard Luy
Matthias Plitzko
Manfred Struschka
Original Assignee
Sanofi Pasteur Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Sa filed Critical Sanofi Pasteur Sa
Publication of PL2766682T3 publication Critical patent/PL2766682T3/pl

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL12769026T 2011-10-05 2012-10-04 Sposób, linia technologiczna i wykorzystanie linii technologicznej do wytwarzania cząstek liofilizowanych PL2766682T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11008057.9A EP2578974A1 (en) 2011-10-05 2011-10-05 Process line for the production of freeze-dried particles

Publications (1)

Publication Number Publication Date
PL2766682T3 true PL2766682T3 (pl) 2017-03-31

Family

ID=46980888

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12769021T PL2764309T3 (pl) 2011-10-05 2012-10-04 Linia technologiczna do wytwarzania liofilizowanych cząstek
PL12769026T PL2766682T3 (pl) 2011-10-05 2012-10-04 Sposób, linia technologiczna i wykorzystanie linii technologicznej do wytwarzania cząstek liofilizowanych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL12769021T PL2764309T3 (pl) 2011-10-05 2012-10-04 Linia technologiczna do wytwarzania liofilizowanych cząstek

Country Status (25)

Country Link
US (2) US9920989B2 (pl)
EP (4) EP2578974A1 (pl)
JP (2) JP5766361B2 (pl)
KR (2) KR101552804B1 (pl)
CN (2) CN103917842B (pl)
AU (2) AU2012320848B8 (pl)
BR (2) BR112014007862B1 (pl)
CA (2) CA2849802C (pl)
CO (2) CO6930306A2 (pl)
CR (2) CR20140159A (pl)
DK (2) DK2764309T3 (pl)
EA (2) EA027602B1 (pl)
ES (2) ES2608427T3 (pl)
HU (2) HUE029973T2 (pl)
IL (2) IL231853A0 (pl)
IN (2) IN2014CN02440A (pl)
MX (2) MX341894B (pl)
MY (2) MY151369A (pl)
PE (2) PE20142141A1 (pl)
PH (2) PH12014500617A1 (pl)
PL (2) PL2764309T3 (pl)
SG (2) SG11201400640VA (pl)
UA (2) UA111859C2 (pl)
WO (2) WO2013050162A1 (pl)
ZA (1) ZA201401930B (pl)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1006722A2 (pt) 2009-04-09 2017-10-10 Entegrion Inc "método de preparação de hemoderivados desidratado, hemoderivados desidratados, bandagem ou auxílio cirúrgico, método para a preparação de plaquetas sanguíneas fixas desidratadas, plaquetas sanguíneas fixas desidratadas, método para o tratamento de um paciente que sofre de um distúrbio sanguíneo e plaquetas de sangue fixas secas por atomização tendo geometria com cavidades esféricas"
US20110142885A1 (en) 2009-09-16 2011-06-16 Velico Medical, Inc. Spray-dried human plasma
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer
UA111631C2 (uk) 2011-10-06 2016-05-25 Санофі Пастер Са Нагрівальний пристрій для роторної барабанної ліофільної сушарки
EP3004767B1 (en) 2013-05-29 2017-12-06 GEA Process Engineering A/S Method of providing inline sterile freeze drying of a product in trays accommodated in a trolley, system for carrying out the method, and use of the method
JP6166006B1 (ja) 2014-07-21 2017-07-19 サノフィ パスツール エスエー 液滴生成のための液体供給装置
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
DE102015105375B4 (de) * 2015-01-07 2016-11-03 Richard Süverkrüp Vorrichtung und Verfahren zur Erzeugung monodisperser gefrorener Tropfen
US9739532B2 (en) * 2015-02-04 2017-08-22 Steven F. Baugh Botanical freeze drying system and method
US10465985B2 (en) 2015-06-01 2019-11-05 Ima Life North America Inc. Bulk freeze drying using spray freezing and agitated drying with dielectric heating
RU2615553C1 (ru) * 2015-10-15 2017-04-05 Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" Способ и устройство непрерывной сублимационной сушки жидких продуктов
EP3167877A1 (en) * 2015-11-12 2017-05-17 Bayer Pharma Aktiengesellschaft Method for the production of freeze-dried pellets comprising factor viii
CN106705574A (zh) * 2015-11-17 2017-05-24 上海东富龙科技股份有限公司 一种固体制剂制造设备和方法
JP6666535B2 (ja) * 2016-01-05 2020-03-18 株式会社あい・あいエナジーアソシエイツ 液体の凍結乾燥装置及び凍結乾燥方法
CN105674691B (zh) * 2016-04-01 2017-11-21 苏州大学 用于收集喷雾冷冻冰球颗粒的双密封式设备及其收集方法
US10507165B2 (en) 2017-05-31 2019-12-17 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using same
US10369077B2 (en) * 2017-05-31 2019-08-06 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using the same
DE102017119649A1 (de) 2017-08-28 2019-02-28 Richard Süverkrüp Verfahren zur kontinuierlichen Herstellung gefriergetrockneter Tropfen in einem geschlossenen Gaskreislauf
ES2779023T3 (es) * 2017-10-20 2020-08-13 Martin Christ Gefriertrocknungsanlagen Gmbh Procedimiento para la determinación a base de presión de un parámetro de producto en un liofilizador, liofilizador y producto de software
KR102450460B1 (ko) * 2017-12-29 2022-09-30 아주대학교산학협력단 초음파 분무기를 이용한 미립구 약제의 양산 시스템
WO2019175954A1 (ja) * 2018-03-13 2019-09-19 株式会社プリス 噴霧凍結造粒乾燥粉体製造装置及び噴霧凍結造粒乾燥粉体製造システム
CN111065874B (zh) * 2018-06-08 2020-12-29 株式会社爱发科 真空冻结干燥装置和真空冻结干燥方法
PE20210462A1 (es) * 2018-07-05 2021-03-08 Bayer Ag METODO PARA LA PRODUCCION DE GRANULOS LIOFILIZADOS QUE COMPRENDEN UN ANTICUERPO ANTI-FACTOR XIa (FXIa) DE LA COAGULACION
EP3864359B1 (en) 2018-10-11 2023-06-28 IMA Life North America Inc. Bulk freeze drying system
WO2020161863A1 (ja) * 2019-02-07 2020-08-13 株式会社アルバック 真空凍結乾燥方法及び真空凍結乾燥装置
US11243029B2 (en) * 2019-04-26 2022-02-08 Purdue Research Foundation Process monitoring and control for lyophilization using a wireless sensor network
CN111207564B (zh) * 2019-09-30 2022-01-04 中国科学院上海硅酸盐研究所 一种冷冻干燥系统及方法
MX2022005974A (es) * 2019-12-09 2022-06-23 Nestle Sa Pasta para bebida.
JP6777350B1 (ja) 2020-05-18 2020-10-28 株式会社エムアイアイ 真空凍結乾燥装置及び真空凍結乾燥方法
TWI860477B (zh) 2020-05-18 2024-11-01 日商Mii股份有限公司 真空凍結乾燥裝置及真空凍結乾燥方法
WO2022030055A1 (ja) * 2020-08-07 2022-02-10 株式会社アルバック 真空凍結乾燥方法、真空凍結乾燥装置用の噴射ノズルおよび真空凍結乾燥装置
JP6887050B1 (ja) * 2020-08-07 2021-06-16 株式会社アルバック 真空凍結乾燥方法および真空凍結乾燥装置
US11874060B2 (en) 2020-11-16 2024-01-16 Sublime Stericeuticals Corporation Continuous throughput lyophilizer-powder filler within a sterile boundary
EP4259063A4 (en) * 2020-12-11 2024-12-18 Merck Sharp & Dohme LLC COMPACT CONTAINER SYSTEM FOR ISOLATION, PROCESSING AND PACKAGING OF PHARMACEUTICAL PRODUCTS
JP7085088B1 (ja) * 2021-08-03 2022-06-16 株式会社エムアイアイ 凍結乾燥物
CN113701457A (zh) * 2021-09-18 2021-11-26 楚天科技股份有限公司 一种冻干系统及冻干方法
CA3234107A1 (en) 2021-10-05 2023-04-13 Florent PERAL Methods for freezing and freeze-drying lipid nanoparticles (lnps) and lnps obtained with the same
US12085337B2 (en) 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods
CN114192067A (zh) * 2021-12-08 2022-03-18 南通东概念新材料有限公司 一种喷雾干燥、液氮速冻、真空冷冻干燥制备颗粒的方法
US12454789B2 (en) 2022-03-16 2025-10-28 Haier Us Appliance Solutions, Inc. Dryer appliance and method for cleaning operation
TW202417038A (zh) 2022-06-15 2024-05-01 法商賽諾菲公司 高度濃縮的抗體組成物
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US12246093B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Methods for making spray dried plasma
US12246266B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Disposable for a spray drying system
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
WO2024059770A1 (en) 2022-09-15 2024-03-21 Velico Medical, Inc. Rapid spray drying system
WO2024184725A1 (en) * 2023-03-03 2024-09-12 Pfizer Inc. Systems and methods for reducing electrostatic force in dynamic freeze drying
WO2024184721A1 (en) * 2023-03-03 2024-09-12 Pfizer Inc. Systems and methods for pre-conditioning frozen bulk in dynamic bulk freeze drying
GB202402626D0 (en) * 2024-02-23 2024-04-10 Ttp Plc Spray freeze drying formation of dry powder compositions
CN120926693A (zh) * 2025-10-11 2025-11-11 天津凯莱英医药科技发展有限公司 喷雾冷冻干燥系统

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2388917A (en) * 1941-10-13 1945-11-13 Hormel & Co Geo A Process for preservation of biological materials and products resulting therefrom
FR1378749A (fr) * 1964-01-07 1964-11-13 Leybold Hochvakuum Anlagen Procédé et dispositif de séchage par congélation
US3303578A (en) 1964-07-29 1967-02-14 William C Rockwell Continuous freeze-drying apparatus
US3601901A (en) 1969-09-12 1971-08-31 Earl L Rader Freeze drying apparatus with removable conveyor and heater structures
US3621587A (en) 1970-08-06 1971-11-23 Smitherm Industries Freeze drying apparatus
US4033048A (en) 1976-01-12 1977-07-05 Clayton Van Ike Freeze drying apparatus
JPS5844703Y2 (ja) 1979-02-01 1983-10-11 クラリオン株式会社 スピ−カの取付構造
JPS55112980A (en) * 1979-02-26 1980-09-01 Nippon Oxygen Co Ltd Freezing drier
DE3105623A1 (de) 1981-02-16 1982-09-02 Erhard Dipl.-Ing.agr. 8000 München Grolitsch Verfahren zur schonenden gefriertrocknung und pulverisierung von empfindlichen trocknungsguetern wie wasserhaltigen lebensmitteln
CA2051092C (en) 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
DE4113512C2 (de) * 1991-04-25 1995-04-20 Grolitsch Lisbeth Verfahren und Vorrichtung zur Gefriertrocknung und Pulverisierung von Lebensmitteln
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation
GB9416582D0 (en) 1994-08-17 1994-10-19 Ici Plc Process for the production of exothermically reacting compositions
AU699042B2 (en) 1995-03-09 1998-11-19 Boc Group, Inc., The Transfer port system
JPH0971536A (ja) 1995-07-03 1997-03-18 Nippon Telegr & Teleph Corp <Ntt> 生物細胞含有液凍結乾燥装置
DE19654134C2 (de) 1996-04-25 2003-08-07 Messer Griesheim Gmbh Verfahren und Einrichtung zum Gefriertrocknen
JP3639783B2 (ja) 2000-10-30 2005-04-20 共和真空技術株式会社 食品・薬品等の凍結乾燥方法および凍結乾燥装置
GB0103620D0 (en) * 2001-02-14 2001-03-28 Prometic Biosciences Ltd Sterile composition and its preparation
US6543155B2 (en) 2001-03-01 2003-04-08 National Agricultural Research Organization Freeze-dried product and process and apparatus for producing it
JP3686594B2 (ja) 2001-06-14 2005-08-24 共和真空技術株式会社 食品・薬品類の凍結乾燥装置における液材料の分注装置
MXPA04004726A (es) 2001-11-19 2004-07-30 Becton Dickinson Co Composiciones farmaceuticas en forma particulada.
JP3942093B2 (ja) 2003-01-28 2007-07-11 株式会社アルバック 噴霧式真空凍結乾燥装置
FR2862306B1 (fr) 2003-11-17 2008-05-30 Aventis Pasteur Composition vaccinale
DE102004005660A1 (de) 2004-02-04 2005-08-25 Rheinische Friedrich-Wilhelms-Universität Bonn Verfahren und Vorrichtung zur Herstellung eines lyophilisierten pharmazeutischen Materials
SE526792C2 (sv) 2004-03-03 2005-11-08 Tetra Laval Holdings & Finance Anordning för evaporativ kylning av en vätskeformig produkt
BRPI0510529A (pt) 2004-05-01 2007-10-30 Agres Ltd processo e aparelho de secagem
CA2574614C (en) 2004-07-23 2013-12-03 Bayer Technology Services Gmbh Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals)
US20060165717A1 (en) 2005-01-25 2006-07-27 Sanofi Pasteur DCchol in newborns
AR054822A1 (es) 2005-07-07 2007-07-18 Sanofi Pasteur Emulsion inmuno adyuvante
AU2007226983A1 (en) 2006-03-20 2007-09-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions
MX2009000660A (es) 2006-07-17 2009-04-08 Glaxosmithkline Biolog Sa Vacuna de influenza.
DE202006018276U1 (de) * 2006-12-01 2007-02-08 Püschner GmbH + Co. KG Mikrowellen-Vakuumtrockungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut
DE102007055488B4 (de) * 2006-12-01 2015-01-22 Püschner GmbH + Co. KG Mikrowellen-Vakuumtrocknungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut
CN101234257B (zh) 2007-02-01 2011-07-27 发泰(天津)科技有限公司 微波旋转薄膜浓缩器
DE102007012795B3 (de) * 2007-03-16 2008-04-10 Püschner GmbH + Co. KG Mikrowellen-Vakuumtrocknungsanlagen und Verfahren zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut mittels Mikrowellen
EP2101131A1 (en) * 2007-12-31 2009-09-16 Terruzzi Fercalx S.p.A. Lyophilization method and system therefor
JP5689687B2 (ja) * 2008-03-05 2015-03-25 サノフィ・パスツールSanofipasteur アジュバント含有ワクチン組成物の安定化方法
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer
UA111631C2 (uk) 2011-10-06 2016-05-25 Санофі Пастер Са Нагрівальний пристрій для роторної барабанної ліофільної сушарки

Also Published As

Publication number Publication date
KR20140088112A (ko) 2014-07-09
IL231853A0 (en) 2014-05-28
CA2849799C (en) 2015-12-08
JP2014530685A (ja) 2014-11-20
MX341894B (es) 2016-09-07
EA201490719A1 (ru) 2014-09-30
ES2608427T3 (es) 2017-04-10
BR112014008001A2 (pt) 2017-04-11
ES2608478T3 (es) 2017-04-11
PE20141979A1 (es) 2014-12-19
WO2013050156A1 (en) 2013-04-11
SG11201400640VA (en) 2014-06-27
CR20140158A (es) 2014-10-30
HUE029973T2 (en) 2017-04-28
CA2849799A1 (en) 2013-04-11
AU2012320848B2 (en) 2015-02-26
IN2014CN02407A (pl) 2015-06-19
PL2764309T3 (pl) 2017-03-31
EP2766682B1 (en) 2016-11-23
MX2014004000A (es) 2014-07-22
EP2764309A1 (en) 2014-08-13
KR101512608B1 (ko) 2015-04-15
KR101552804B1 (ko) 2015-09-11
BR112014007862B1 (pt) 2021-01-19
MY151369A (en) 2014-05-16
CN103917841A (zh) 2014-07-09
AU2012320854A1 (en) 2014-05-15
BR112014007862A2 (pt) 2017-04-18
UA111858C2 (uk) 2016-06-24
PH12014500617A1 (en) 2019-06-03
US20140230266A1 (en) 2014-08-21
EP2578974A1 (en) 2013-04-10
PE20142141A1 (es) 2015-01-04
AU2012320848A1 (en) 2014-05-15
MX359904B (es) 2018-10-16
ZA201401930B (en) 2015-02-25
IN2014CN02440A (pl) 2015-06-19
JP5766361B2 (ja) 2015-08-19
BR112014008001B1 (pt) 2021-01-19
EA201490723A1 (ru) 2014-08-29
CO6930351A2 (es) 2014-04-28
EP3211355A1 (en) 2017-08-30
IL231849A0 (en) 2014-05-28
MX2014004041A (es) 2014-08-01
AU2012320848B8 (en) 2015-03-05
SG11201400641QA (en) 2014-08-28
CA2849802C (en) 2015-12-08
HK1200207A1 (en) 2015-07-31
JP2014530061A (ja) 2014-11-17
EP2764309B1 (en) 2016-11-23
US9920989B2 (en) 2018-03-20
CR20140159A (es) 2014-10-30
EA027602B1 (ru) 2017-08-31
US10006706B2 (en) 2018-06-26
CO6930306A2 (es) 2014-04-28
EA027630B1 (ru) 2017-08-31
HK1199656A1 (en) 2015-07-10
US20140245629A1 (en) 2014-09-04
WO2013050162A1 (en) 2013-04-11
CN103917842A (zh) 2014-07-09
WO2013050156A8 (en) 2013-06-13
EP2766682A1 (en) 2014-08-20
AU2012320854B2 (en) 2015-02-19
MY152319A (en) 2014-09-08
CN103917841B (zh) 2015-07-08
CA2849802A1 (en) 2013-04-11
CN103917842B (zh) 2015-08-05
HUE030970T2 (en) 2017-06-28
UA111859C2 (uk) 2016-06-24
DK2766682T3 (en) 2017-01-09
KR20140088113A (ko) 2014-07-09
JP5728135B2 (ja) 2015-06-03
DK2764309T3 (en) 2017-01-09
PH12014500621A1 (en) 2014-05-05

Similar Documents

Publication Publication Date Title
PL2766682T3 (pl) Sposób, linia technologiczna i wykorzystanie linii technologicznej do wytwarzania cząstek liofilizowanych
IL269322B (en) Methylphenidate-medications, processes for their preparation and use
PL2914402T3 (pl) Ukształtowane cząstki ścierne oraz wyroby ścierne obejmujące sposoby ich wytwarzania
IL231852A0 (en) Process line for the production of freeze-dried particles
IL231591A (en) Preserved benzyl indazoles, a process for their preparation and use
SG10201703051WA (en) Compounds and methods for the production of suckerin and uses thereof
TWI561298B (en) Continuous emulsification-aggregation process for the production of particles and reactor for the process
EP2540672A4 (en) COMPOSITE PARTICLES AND METHOD FOR PRODUCING THE SAME
SG11201504404SA (en) Ring and process for producing the same
PH12014500046A1 (en) Process and product
ZA201402354B (en) Product and process for its manufacture
EP2938587A4 (en) CERAMIC PARTICLES AND METHOD FOR THE PREPARATION THEREOF
EP2835686A4 (en) FINE ELECTRETIC PARTICLES AND METHOD FOR THE PRODUCTION THEREOF
ZA201407558B (en) Itq-49 material, method for the production thereof and use of same
EP2691354A4 (en) CERAMIC PARTICLES AND MANUFACTURING METHOD THEREFOR
PL398021A1 (pl) Nowa diacylo-sn-glicero-3-fosfocholina oraz sposób jej otrzymywania
PL398018A1 (pl) Nowa diacylo-sn-glicero-3-fosfocholina oraz sposób jej otrzymywania
PL395229A1 (pl) Sposób wytwarzania pieczywa i pieczywo
GB201122368D0 (en) Process, use and product
PL395175A1 (pl) Nowe pochodne dekstrometorfanu i sposób ich wytwarzania
PL2736697T3 (pl) Korpus komórkowy i sposób jego wytwarzania
GB201111447D0 (en) Product and process
GB201111437D0 (en) Product and process