MX341894B - Línea de proceso para la producción de partículas criodesecadas. - Google Patents

Línea de proceso para la producción de partículas criodesecadas.

Info

Publication number
MX341894B
MX341894B MX2014004000A MX2014004000A MX341894B MX 341894 B MX341894 B MX 341894B MX 2014004000 A MX2014004000 A MX 2014004000A MX 2014004000 A MX2014004000 A MX 2014004000A MX 341894 B MX341894 B MX 341894B
Authority
MX
Mexico
Prior art keywords
freeze
production
particles
dryer
process line
Prior art date
Application number
MX2014004000A
Other languages
English (en)
Other versions
MX2014004000A (es
Inventor
Luy Bernhard
Plitzko Matthias
Struschka Manfred
Original Assignee
Sanofi Pasteur S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur S A filed Critical Sanofi Pasteur S A
Publication of MX2014004000A publication Critical patent/MX2014004000A/es
Publication of MX341894B publication Critical patent/MX341894B/es

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

Una línea de proceso (300) para la producción de partículas criodesecadas bajo condiciones cerradas que comprende al menos una cámara de aspersión (302) para la generación de gotitas y criocongelación de las gotitas de líquido para formar partículas y un criodesecador a granel (304) para criodesecar las partículas, el criodesecador (304), comprende un tambor giratorio para recibir las partículas. Además, una sección de transferencia (308) se proporciona para una transferencia de producto desde la cámara de aspersión (302) hasta el criodesecador (304). Para la producción de partículas bajo condiciones cerradas de extremo a extremo, cada uno de los dispositivos (302, 304) y la sección de transferencia (308) se adapta por separado para la operación de preservar esterilidad del producto que se criodesecará y/o tendrá contención.
MX2014004000A 2011-10-05 2012-10-04 Línea de proceso para la producción de partículas criodesecadas. MX341894B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11008057.9A EP2578974A1 (en) 2011-10-05 2011-10-05 Process line for the production of freeze-dried particles
PCT/EP2012/004162 WO2013050156A1 (en) 2011-10-05 2012-10-04 Process line for the production of freeze-dried particles

Publications (2)

Publication Number Publication Date
MX2014004000A MX2014004000A (es) 2014-07-22
MX341894B true MX341894B (es) 2016-09-07

Family

ID=46980888

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014004041A MX359904B (es) 2011-10-05 2012-10-04 Línea de proceso para la producción de partículas criodesecadas.
MX2014004000A MX341894B (es) 2011-10-05 2012-10-04 Línea de proceso para la producción de partículas criodesecadas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2014004041A MX359904B (es) 2011-10-05 2012-10-04 Línea de proceso para la producción de partículas criodesecadas.

Country Status (25)

Country Link
US (2) US9920989B2 (es)
EP (4) EP2578974A1 (es)
JP (2) JP5728135B2 (es)
KR (2) KR101512608B1 (es)
CN (2) CN103917842B (es)
AU (2) AU2012320854B2 (es)
BR (2) BR112014008001B1 (es)
CA (2) CA2849799C (es)
CO (2) CO6930351A2 (es)
CR (2) CR20140159A (es)
DK (2) DK2764309T3 (es)
EA (2) EA027630B1 (es)
ES (2) ES2608427T3 (es)
HU (2) HUE029973T2 (es)
IL (2) IL231849A0 (es)
IN (2) IN2014CN02440A (es)
MX (2) MX359904B (es)
MY (2) MY151369A (es)
PE (2) PE20142141A1 (es)
PH (2) PH12014500621A1 (es)
PL (2) PL2764309T3 (es)
SG (2) SG11201400641QA (es)
UA (2) UA111859C2 (es)
WO (2) WO2013050162A1 (es)
ZA (1) ZA201401930B (es)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010117976A1 (en) 2009-04-09 2010-10-14 Entegrion, Inc Spray-dried blood products and methods of making same
US20110142885A1 (en) 2009-09-16 2011-06-16 Velico Medical, Inc. Spray-dried human plasma
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
UA111631C2 (uk) 2011-10-06 2016-05-25 Санофі Пастер Са Нагрівальний пристрій для роторної барабанної ліофільної сушарки
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer
JP6173495B2 (ja) 2013-05-29 2017-08-02 ゲア・プロセス・エンジニアリング・アクティーゼルスカブ トロリに収容されたトレイ内の製品の直列滅菌凍結乾燥を実現する方法、方法を実施するためのシステム、および方法の使用
CN107073350B (zh) 2014-07-21 2019-11-15 赛诺菲巴斯德股份公司 用于产生液滴的液体给送装置
US9561184B2 (en) * 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
DE102015105375B4 (de) 2015-01-07 2016-11-03 Richard Süverkrüp Vorrichtung und Verfahren zur Erzeugung monodisperser gefrorener Tropfen
US9739532B2 (en) * 2015-02-04 2017-08-22 Steven F. Baugh Botanical freeze drying system and method
ES2760075T3 (es) * 2015-06-01 2020-05-13 Ima Life North America Inc Liofilización a granel utilizando congelación por pulverización y secado en agitación con calentamiento
RU2615553C1 (ru) * 2015-10-15 2017-04-05 Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" Способ и устройство непрерывной сублимационной сушки жидких продуктов
EP3167877A1 (en) 2015-11-12 2017-05-17 Bayer Pharma Aktiengesellschaft Method for the production of freeze-dried pellets comprising factor viii
CN106705574A (zh) * 2015-11-17 2017-05-24 上海东富龙科技股份有限公司 一种固体制剂制造设备和方法
JP6666535B2 (ja) * 2016-01-05 2020-03-18 株式会社あい・あいエナジーアソシエイツ 液体の凍結乾燥装置及び凍結乾燥方法
CN105674691B (zh) * 2016-04-01 2017-11-21 苏州大学 用于收集喷雾冷冻冰球颗粒的双密封式设备及其收集方法
US10507165B2 (en) 2017-05-31 2019-12-17 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using same
US10369077B2 (en) * 2017-05-31 2019-08-06 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using the same
DE102017119649A1 (de) 2017-08-28 2019-02-28 Richard Süverkrüp Verfahren zur kontinuierlichen Herstellung gefriergetrockneter Tropfen in einem geschlossenen Gaskreislauf
ES2779023T3 (es) * 2017-10-20 2020-08-13 Martin Christ Gefriertrocknungsanlagen Gmbh Procedimiento para la determinación a base de presión de un parámetro de producto en un liofilizador, liofilizador y producto de software
KR102450460B1 (ko) * 2017-12-29 2022-09-30 아주대학교산학협력단 초음파 분무기를 이용한 미립구 약제의 양산 시스템
WO2019175954A1 (ja) * 2018-03-13 2019-09-19 株式会社プリス 噴霧凍結造粒乾燥粉体製造装置及び噴霧凍結造粒乾燥粉体製造システム
WO2019235036A1 (ja) * 2018-06-08 2019-12-12 株式会社アルバック 凍結真空乾燥装置及び凍結真空乾燥方法
WO2020008022A1 (en) * 2018-07-05 2020-01-09 Bayer Aktiengesellschaft METHOD FOR THE PRODUCTION OF FREEZE-DRIED PELLETS COMPRISING AN ANTI-COAGULATION FACTOR XIa (FXIa) ANTIBODY
ES2955971T3 (es) 2018-10-11 2023-12-11 Ima Life North America Inc Sistema de liofilización a granel
WO2020161863A1 (ja) * 2019-02-07 2020-08-13 株式会社アルバック 真空凍結乾燥方法及び真空凍結乾燥装置
US11243029B2 (en) * 2019-04-26 2022-02-08 Purdue Research Foundation Process monitoring and control for lyophilization using a wireless sensor network
CN111207564B (zh) * 2019-09-30 2022-01-04 中国科学院上海硅酸盐研究所 一种冷冻干燥系统及方法
US20230000120A1 (en) * 2019-12-09 2023-01-05 Societe Des Produits Nestle S.A. Beverage paste
JP6777350B1 (ja) 2020-05-18 2020-10-28 株式会社エムアイアイ 真空凍結乾燥装置及び真空凍結乾燥方法
TWI860477B (zh) 2020-05-18 2024-11-01 日商Ｍｉｉ股份有限公司 真空凍結乾燥裝置及真空凍結乾燥方法
WO2022030055A1 (ja) * 2020-08-07 2022-02-10 株式会社アルバック 真空凍結乾燥方法、真空凍結乾燥装置用の噴射ノズルおよび真空凍結乾燥装置
JP6887050B1 (ja) * 2020-08-07 2021-06-16 株式会社アルバック 真空凍結乾燥方法および真空凍結乾燥装置
US11874060B2 (en) 2020-11-16 2024-01-16 Sublime Stericeuticals Corporation Continuous throughput lyophilizer-powder filler within a sterile boundary
JP7793626B2 (ja) * 2020-12-11 2026-01-05 メルク・シャープ・アンド・ドーム・エルエルシー 医薬品を隔離、処理、および包装するための小型封じ込めシステム
JP7085088B1 (ja) * 2021-08-03 2022-06-16 株式会社エムアイアイ 凍結乾燥物
CN113701457A (zh) * 2021-09-18 2021-11-26 楚天科技股份有限公司 一种冻干系统及冻干方法
AU2022359812A1 (en) 2021-10-05 2024-05-16 Sanofi Pasteur Inc. METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME
US12085337B2 (en) 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods
CN114192067A (zh) * 2021-12-08 2022-03-18 南通东概念新材料有限公司 一种喷雾干燥、液氮速冻、真空冷冻干燥制备颗粒的方法
US12454789B2 (en) 2022-03-16 2025-10-28 Haier Us Appliance Solutions, Inc. Dryer appliance and method for cleaning operation
TW202417038A (zh) 2022-06-15 2024-05-01 法商賽諾菲公司 高度濃縮的抗體組成物
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
US12539355B2 (en) 2022-09-15 2026-02-03 Velico Medical, Inc. Dryer for a spray drying system
WO2024059770A1 (en) 2022-09-15 2024-03-21 Velico Medical, Inc. Rapid spray drying system
US12246093B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Methods for making spray dried plasma
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US12571587B2 (en) 2022-09-15 2026-03-10 Velico Medical, Inc. Finishing apparatus for a spray drying system
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system
US12246266B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Disposable for a spray drying system
WO2024184725A1 (en) * 2023-03-03 2024-09-12 Pfizer Inc. Systems and methods for reducing electrostatic force in dynamic freeze drying
WO2024184721A1 (en) * 2023-03-03 2024-09-12 Pfizer Inc. Systems and methods for pre-conditioning frozen bulk in dynamic bulk freeze drying
GB202402626D0 (en) * 2024-02-23 2024-04-10 Ttp Plc Spray freeze drying formation of dry powder compositions
CN120926693B (zh) * 2025-10-11 2026-01-02 天津凯莱英医药科技发展有限公司 喷雾冷冻干燥系统

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2388917A (en) * 1941-10-13 1945-11-13 Hormel & Co Geo A Process for preservation of biological materials and products resulting therefrom
FR1378749A (fr) * 1964-01-07 1964-11-13 Leybold Hochvakuum Anlagen Procédé et dispositif de séchage par congélation
US3303578A (en) 1964-07-29 1967-02-14 William C Rockwell Continuous freeze-drying apparatus
US3601901A (en) 1969-09-12 1971-08-31 Earl L Rader Freeze drying apparatus with removable conveyor and heater structures
US3621587A (en) 1970-08-06 1971-11-23 Smitherm Industries Freeze drying apparatus
US4033048A (en) * 1976-01-12 1977-07-05 Clayton Van Ike Freeze drying apparatus
JPS5844703Y2 (ja) 1979-02-01 1983-10-11 クラリオン株式会社 スピ−カの取付構造
JPS55112980A (en) * 1979-02-26 1980-09-01 Nippon Oxygen Co Ltd Freezing drier
DE3105623A1 (de) 1981-02-16 1982-09-02 Erhard Dipl.-Ing.agr. 8000 München Grolitsch Verfahren zur schonenden gefriertrocknung und pulverisierung von empfindlichen trocknungsguetern wie wasserhaltigen lebensmitteln
CA2051092C (en) 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
DE4113512C2 (de) * 1991-04-25 1995-04-20 Grolitsch Lisbeth Verfahren und Vorrichtung zur Gefriertrocknung und Pulverisierung von Lebensmitteln
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation
GB9416582D0 (en) * 1994-08-17 1994-10-19 Ici Plc Process for the production of exothermically reacting compositions
AU699042B2 (en) 1995-03-09 1998-11-19 Boc Group, Inc., The Transfer port system
JPH0971536A (ja) 1995-07-03 1997-03-18 Nippon Telegr & Teleph Corp <Ntt> 生物細胞含有液凍結乾燥装置
DE19654134C2 (de) 1996-04-25 2003-08-07 Messer Griesheim Gmbh Verfahren und Einrichtung zum Gefriertrocknen
JP3639783B2 (ja) 2000-10-30 2005-04-20 共和真空技術株式会社 食品・薬品等の凍結乾燥方法および凍結乾燥装置
GB0103620D0 (en) * 2001-02-14 2001-03-28 Prometic Biosciences Ltd Sterile composition and its preparation
US6543155B2 (en) 2001-03-01 2003-04-08 National Agricultural Research Organization Freeze-dried product and process and apparatus for producing it
JP3686594B2 (ja) 2001-06-14 2005-08-24 共和真空技術株式会社 食品・薬品類の凍結乾燥装置における液材料の分注装置
CN1607941A (zh) 2001-11-19 2005-04-20 贝克顿迪肯森公司 粒状药物组合物
JP3942093B2 (ja) 2003-01-28 2007-07-11 株式会社アルバック 噴霧式真空凍結乾燥装置
FR2862306B1 (fr) 2003-11-17 2008-05-30 Aventis Pasteur Composition vaccinale
DE102004005660A1 (de) * 2004-02-04 2005-08-25 Rheinische Friedrich-Wilhelms-Universität Bonn Verfahren und Vorrichtung zur Herstellung eines lyophilisierten pharmazeutischen Materials
SE526792C2 (sv) * 2004-03-03 2005-11-08 Tetra Laval Holdings & Finance Anordning för evaporativ kylning av en vätskeformig produkt
CA2565136A1 (en) 2004-05-01 2005-11-10 Agresearch Limited Drying process and apparatus
CA2574614C (en) 2004-07-23 2013-12-03 Bayer Technology Services Gmbh Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals)
US20060165717A1 (en) 2005-01-25 2006-07-27 Sanofi Pasteur DCchol in newborns
AR054822A1 (es) 2005-07-07 2007-07-18 Sanofi Pasteur Emulsion inmuno adyuvante
US20070218138A1 (en) 2006-03-20 2007-09-20 Bittorf Kevin J Pharmaceutical Compositions
HRP20140488T1 (hr) 2006-07-17 2014-07-04 Glaxosmithkline Biologicals S.A. Cjepivo protiv influence
DE202006018276U1 (de) 2006-12-01 2007-02-08 Püschner GmbH + Co. KG Mikrowellen-Vakuumtrockungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut
DE102007055488B4 (de) * 2006-12-01 2015-01-22 Püschner GmbH + Co. KG Mikrowellen-Vakuumtrocknungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut
CN101234257B (zh) 2007-02-01 2011-07-27 发泰（天津）科技有限公司 微波旋转薄膜浓缩器
DE102007012795B3 (de) * 2007-03-16 2008-04-10 Püschner GmbH + Co. KG Mikrowellen-Vakuumtrocknungsanlagen und Verfahren zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut mittels Mikrowellen
EP2101131A1 (en) * 2007-12-31 2009-09-16 Terruzzi Fercalx S.p.A. Lyophilization method and system therefor
ES2615390T3 (es) 2008-03-05 2017-06-06 Sanofi Pasteur Proceso para estabilizar una composición de vacuna que contiene adyuvante
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
UA111631C2 (uk) 2011-10-06 2016-05-25 Санофі Пастер Са Нагрівальний пристрій для роторної барабанної ліофільної сушарки
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer

Also Published As

Publication number Publication date
MY151369A (en) 2014-05-16
MY152319A (en) 2014-09-08
IN2014CN02440A (es) 2015-06-19
CN103917841A (zh) 2014-07-09
CN103917841B (zh) 2015-07-08
PL2766682T3 (pl) 2017-03-31
US9920989B2 (en) 2018-03-20
MX2014004041A (es) 2014-08-01
CN103917842A (zh) 2014-07-09
CR20140159A (es) 2014-10-30
EA027602B1 (ru) 2017-08-31
CO6930306A2 (es) 2014-04-28
JP2014530685A (ja) 2014-11-20
MX2014004000A (es) 2014-07-22
AU2012320848B2 (en) 2015-02-26
JP5766361B2 (ja) 2015-08-19
EA201490719A1 (ru) 2014-09-30
PH12014500617A1 (en) 2019-06-03
AU2012320848B8 (en) 2015-03-05
US10006706B2 (en) 2018-06-26
WO2013050162A1 (en) 2013-04-11
CA2849802A1 (en) 2013-04-11
IN2014CN02407A (es) 2015-06-19
CR20140158A (es) 2014-10-30
ZA201401930B (en) 2015-02-25
ES2608427T3 (es) 2017-04-10
KR101552804B1 (ko) 2015-09-11
UA111858C2 (uk) 2016-06-24
JP2014530061A (ja) 2014-11-17
DK2766682T3 (en) 2017-01-09
HUE030970T2 (en) 2017-06-28
BR112014007862B1 (pt) 2021-01-19
IL231853A0 (en) 2014-05-28
US20140230266A1 (en) 2014-08-21
HK1200207A1 (en) 2015-07-31
EP2578974A1 (en) 2013-04-10
KR20140088113A (ko) 2014-07-09
DK2764309T3 (en) 2017-01-09
US20140245629A1 (en) 2014-09-04
AU2012320848A1 (en) 2014-05-15
CN103917842B (zh) 2015-08-05
HUE029973T2 (en) 2017-04-28
KR20140088112A (ko) 2014-07-09
PH12014500621A1 (en) 2014-05-05
WO2013050156A8 (en) 2013-06-13
PE20142141A1 (es) 2015-01-04
WO2013050156A1 (en) 2013-04-11
KR101512608B1 (ko) 2015-04-15
SG11201400641QA (en) 2014-08-28
HK1199656A1 (en) 2015-07-10
EP2764309A1 (en) 2014-08-13
EA201490723A1 (ru) 2014-08-29
AU2012320854B2 (en) 2015-02-19
UA111859C2 (uk) 2016-06-24
CA2849799C (en) 2015-12-08
EP3211355A1 (en) 2017-08-30
BR112014008001B1 (pt) 2021-01-19
CA2849802C (en) 2015-12-08
BR112014008001A2 (pt) 2017-04-11
PL2764309T3 (pl) 2017-03-31
CA2849799A1 (en) 2013-04-11
AU2012320854A1 (en) 2014-05-15
SG11201400640VA (en) 2014-06-27
PE20141979A1 (es) 2014-12-19
BR112014007862A2 (pt) 2017-04-18
EA027630B1 (ru) 2017-08-31
ES2608478T3 (es) 2017-04-11
EP2764309B1 (en) 2016-11-23
IL231849A0 (en) 2014-05-28
MX359904B (es) 2018-10-16
JP5728135B2 (ja) 2015-06-03
EP2766682A1 (en) 2014-08-20
EP2766682B1 (en) 2016-11-23
CO6930351A2 (es) 2014-04-28

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