IN2014CN02407A - - Google Patents
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- Publication number
- IN2014CN02407A IN2014CN02407A IN2407CHN2014A IN2014CN02407A IN 2014CN02407 A IN2014CN02407 A IN 2014CN02407A IN 2407CHN2014 A IN2407CHN2014 A IN 2407CHN2014A IN 2014CN02407 A IN2014CN02407 A IN 2014CN02407A
- Authority
- IN
- India
- Prior art keywords
- freeze
- particles
- production
- spray chamber
- freeze dryer
- Prior art date
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
- F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Drying Of Solid Materials (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Oxygen, Ozone, And Oxides In General (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A process line (300) for the production of freeze dried particles under closed conditions comprising at least a spray chamber (302) for droplet generation and freeze congealing of the liquid droplets to form particles and a bulk freeze dryer (304) for freeze drying the particles the freeze dryer (304) comprising a rotary drum for receiving the particles. Further a transfer section (308) is provided for a product transfer from the spray chamber (302) to the freeze dryer (304). For the production of the particles under end to end closed conditions each of the devices (302 304) and of the transfer section (308) is separately adapted for operation preserving sterility of the product to be freeze dried and/or containment.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11008057.9A EP2578974A1 (en) | 2011-10-05 | 2011-10-05 | Process line for the production of freeze-dried particles |
| PCT/EP2012/004162 WO2013050156A1 (en) | 2011-10-05 | 2012-10-04 | Process line for the production of freeze-dried particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02407A true IN2014CN02407A (en) | 2015-06-19 |
Family
ID=46980888
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2407CHN2014 IN2014CN02407A (en) | 2011-10-05 | 2012-10-04 | |
| IN2440CHN2014 IN2014CN02440A (en) | 2011-10-05 | 2012-10-04 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2440CHN2014 IN2014CN02440A (en) | 2011-10-05 | 2012-10-04 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US10006706B2 (en) |
| EP (4) | EP2578974A1 (en) |
| JP (2) | JP5766361B2 (en) |
| KR (2) | KR101512608B1 (en) |
| CN (2) | CN103917841B (en) |
| AU (2) | AU2012320848B8 (en) |
| BR (2) | BR112014008001B1 (en) |
| CA (2) | CA2849799C (en) |
| CO (2) | CO6930306A2 (en) |
| CR (2) | CR20140159A (en) |
| DK (2) | DK2764309T3 (en) |
| EA (2) | EA027602B1 (en) |
| ES (2) | ES2608427T3 (en) |
| HK (2) | HK1199656A1 (en) |
| HU (2) | HUE029973T2 (en) |
| IL (2) | IL231853A0 (en) |
| IN (2) | IN2014CN02407A (en) |
| MX (2) | MX359904B (en) |
| MY (2) | MY151369A (en) |
| PE (2) | PE20142141A1 (en) |
| PL (2) | PL2764309T3 (en) |
| SG (2) | SG11201400640VA (en) |
| UA (2) | UA111858C2 (en) |
| WO (2) | WO2013050162A1 (en) |
| ZA (1) | ZA201401930B (en) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140083628A1 (en) | 2012-09-27 | 2014-03-27 | Velico Medical, Inc. | Spray drier assembly for automated spray drying |
| EP2578974A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Process line for the production of freeze-dried particles |
| EP2578975A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum freeze-dryer |
| UA111631C2 (en) | 2011-10-06 | 2016-05-25 | Санофі Пастер Са | HEATING DEVICE FOR ROTOR DRUM LYOPHILE DRYER |
| EP2578976A1 (en) | 2011-10-06 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum for use in a vacuum freeze-dryer |
| WO2014190992A1 (en) | 2013-05-29 | 2014-12-04 | Gea Process Engineering A/S | Method of providing inline sterile freeze drying of a product in trays accommodated in a trolley, system for carrying out the method, and use of the method |
| US10533800B2 (en) | 2014-07-21 | 2020-01-14 | Sanofi Pasteur Sa | Liquid feeding device for the generation of droplets |
| US9561184B2 (en) * | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
| DE102015105375B4 (en) | 2015-01-07 | 2016-11-03 | Richard Süverkrüp | Apparatus and method for producing monodisperse frozen drops |
| US9739532B2 (en) * | 2015-02-04 | 2017-08-22 | Steven F. Baugh | Botanical freeze drying system and method |
| EP3303958B1 (en) * | 2015-06-01 | 2019-10-09 | IMA Life North America Inc. | Bulk freeze drying using spray freezing and agitated drying with heating |
| RU2615553C1 (en) * | 2015-10-15 | 2017-04-05 | Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" | Method and device for continuous dehydrofreezing of liquid products |
| EP3167877A1 (en) | 2015-11-12 | 2017-05-17 | Bayer Pharma Aktiengesellschaft | Method for the production of freeze-dried pellets comprising factor viii |
| CN106705574A (en) * | 2015-11-17 | 2017-05-24 | 上海东富龙科技股份有限公司 | Solid preparation fabrication equipment and method |
| JP6666535B2 (en) * | 2016-01-05 | 2020-03-18 | 株式会社あい・あいエナジーアソシエイツ | Liquid freeze drying apparatus and freeze drying method |
| CN105674691B (en) * | 2016-04-01 | 2017-11-21 | 苏州大学 | For collecting the Dual-sealing equipment and its collection method of spray chilling ice hockey particle |
| US10507165B2 (en) | 2017-05-31 | 2019-12-17 | Adienne Pharma & Biotech Sa | Multi chamber flexible bag and methods of using same |
| US10369077B2 (en) * | 2017-05-31 | 2019-08-06 | Adienne Pharma & Biotech Sa | Multi chamber flexible bag and methods of using the same |
| DE102017119649A1 (en) | 2017-08-28 | 2019-02-28 | Richard Süverkrüp | Process for the continuous production of freeze-dried droplets in a closed gas cycle |
| EP3473959B1 (en) * | 2017-10-20 | 2020-02-12 | Martin Christ Gefriertrocknungsanlagen GmbH | Freeze-dryer, software product and method for pressure-based determination of a product parameter in a freeze-dryer. |
| KR102450460B1 (en) * | 2017-12-29 | 2022-09-30 | 아주대학교산학협력단 | Mass production system of microsphere drug using ultrasonic atomizer |
| JP7038435B2 (en) * | 2018-03-13 | 2022-03-18 | 株式会社プリス | Spray freeze granulation dry powder production equipment and spray freeze granulation dry powder production system |
| CN111065874B (en) * | 2018-06-08 | 2020-12-29 | 株式会社爱发科 | Vacuum freeze-drying device and vacuum freeze-drying method |
| TW202034898A (en) * | 2018-07-05 | 2020-10-01 | 德商拜耳廠股份有限公司 | Novel stable high-concentration formulation for anti-fxia antibodies |
| WO2020161863A1 (en) * | 2019-02-07 | 2020-08-13 | 株式会社アルバック | Vacuum-freeze drying method and vacuum-freeze drying device |
| US11243029B2 (en) * | 2019-04-26 | 2022-02-08 | Purdue Research Foundation | Process monitoring and control for lyophilization using a wireless sensor network |
| CN111207564B (en) * | 2019-09-30 | 2022-01-04 | 中国科学院上海硅酸盐研究所 | Freeze drying system and method |
| TW202202792A (en) * | 2020-05-18 | 2022-01-16 | 日商Ｍｉｉ股份有限公司 | Vacuum freeze-drying device and vacuum freeze-drying method |
| JP6777350B1 (en) | 2020-05-18 | 2020-10-28 | 株式会社エムアイアイ | Vacuum freeze-drying equipment and vacuum freeze-drying method |
| JP6887050B1 (en) * | 2020-08-07 | 2021-06-16 | 株式会社アルバック | Vacuum freeze-drying method and vacuum freeze-drying equipment |
| US20230168034A1 (en) * | 2020-08-07 | 2023-06-01 | Ulvac, Inc. | Vacuum freeze-drying method, injection nozzle for a vacuum freeze-drying apparatus, and vacuum freeze-drying apparatus |
| WO2022104274A1 (en) * | 2020-11-16 | 2022-05-19 | Sublime Stericeuticals Corporation | Continuous throughput lyophilizer/powder filler within a sterile boundary |
| JP7085088B1 (en) * | 2021-08-03 | 2022-06-16 | 株式会社エムアイアイ | Freeze-dried |
| KR20240065326A (en) | 2021-10-05 | 2024-05-14 | 사노피 | Method for freezing and freeze-drying lipid nanoparticles (LP) and LNP obtained using the same |
| US20230122361A1 (en) * | 2021-10-20 | 2023-04-20 | DSM Sales & Manufacturing, Inc. | Freeze-drying systems and methods |
| WO2023242347A1 (en) | 2022-06-15 | 2023-12-21 | Sanofi | Highly concentrated antibody compositions |
| US11975274B2 (en) | 2022-09-15 | 2024-05-07 | Velico Medical, Inc. | Blood plasma product |
| US11841189B1 (en) | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
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| JP5689687B2 (en) | 2008-03-05 | 2015-03-25 | サノフィ・パスツールＳａｎｏｆｉｐａｓｔｅｕｒ | Method for stabilizing an adjuvant-containing vaccine composition |
| EP2578974A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Process line for the production of freeze-dried particles |
| EP2578975A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum freeze-dryer |
| UA111631C2 (en) | 2011-10-06 | 2016-05-25 | Санофі Пастер Са | HEATING DEVICE FOR ROTOR DRUM LYOPHILE DRYER |
| EP2578976A1 (en) | 2011-10-06 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum for use in a vacuum freeze-dryer |
-
2011
- 2011-10-05 EP EP11008057.9A patent/EP2578974A1/en not_active Withdrawn
-
2012
- 2012-04-10 UA UAA201404683A patent/UA111858C2/en unknown
- 2012-04-10 UA UAA201404685A patent/UA111859C2/en unknown
- 2012-10-04 PL PL12769021T patent/PL2764309T3/en unknown
- 2012-10-04 AU AU2012320848A patent/AU2012320848B8/en not_active Ceased
- 2012-10-04 EA EA201490723A patent/EA027602B1/en not_active IP Right Cessation
- 2012-10-04 PE PE2014000480A patent/PE20142141A1/en not_active Application Discontinuation
- 2012-10-04 IN IN2407CHN2014 patent/IN2014CN02407A/en unknown
- 2012-10-04 WO PCT/EP2012/004168 patent/WO2013050162A1/en active Application Filing
- 2012-10-04 US US14/348,869 patent/US10006706B2/en active Active
- 2012-10-04 CN CN201280049533.8A patent/CN103917841B/en active Active
- 2012-10-04 PL PL12769026T patent/PL2766682T3/en unknown
- 2012-10-04 JP JP2014533792A patent/JP5766361B2/en active Active
- 2012-10-04 MY MYPI2014000743 patent/MY151369A/en unknown
- 2012-10-04 EP EP16199831.5A patent/EP3211355A1/en not_active Withdrawn
- 2012-10-04 IN IN2440CHN2014 patent/IN2014CN02440A/en unknown
- 2012-10-04 CA CA2849799A patent/CA2849799C/en not_active Expired - Fee Related
- 2012-10-04 EP EP12769026.1A patent/EP2766682B1/en active Active
- 2012-10-04 HU HUE12769026A patent/HUE029973T2/en unknown
- 2012-10-04 PE PE2014000479A patent/PE20141979A1/en not_active Application Discontinuation
- 2012-10-04 SG SG11201400640VA patent/SG11201400640VA/en unknown
- 2012-10-04 AU AU2012320854A patent/AU2012320854B2/en active Active
- 2012-10-04 EP EP12769021.2A patent/EP2764309B1/en active Active
- 2012-10-04 CA CA2849802A patent/CA2849802C/en not_active Expired - Fee Related
- 2012-10-04 BR BR112014008001-1A patent/BR112014008001B1/en active IP Right Grant
- 2012-10-04 CN CN201280049534.2A patent/CN103917842B/en active Active
- 2012-10-04 ES ES12769021.2T patent/ES2608427T3/en active Active
- 2012-10-04 DK DK12769021.2T patent/DK2764309T3/en active
- 2012-10-04 MX MX2014004041A patent/MX359904B/en active IP Right Grant
- 2012-10-04 SG SG11201400641QA patent/SG11201400641QA/en unknown
- 2012-10-04 US US14/348,877 patent/US9920989B2/en active Active
- 2012-10-04 ES ES12769026.1T patent/ES2608478T3/en active Active
- 2012-10-04 DK DK12769026.1T patent/DK2766682T3/en active
- 2012-10-04 EA EA201490719A patent/EA027630B1/en not_active IP Right Cessation
- 2012-10-04 HU HUE12769021A patent/HUE030970T2/en unknown
- 2012-10-04 BR BR112014007862-9A patent/BR112014007862B1/en active IP Right Grant
- 2012-10-04 MX MX2014004000A patent/MX341894B/en active IP Right Grant
- 2012-10-04 KR KR1020147011244A patent/KR101512608B1/en active IP Right Grant
- 2012-10-04 JP JP2014533796A patent/JP5728135B2/en active Active
- 2012-10-04 KR KR1020147011243A patent/KR101552804B1/en active IP Right Grant
- 2012-10-04 WO PCT/EP2012/004162 patent/WO2013050156A1/en active Application Filing
- 2012-10-04 MY MYPI2014000783 patent/MY152319A/en unknown
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2014
- 2014-03-17 ZA ZA2014/01930A patent/ZA201401930B/en unknown
- 2014-03-31 IL IL231853A patent/IL231853A0/en unknown
- 2014-03-31 IL IL231849A patent/IL231849A0/en unknown
- 2014-04-04 CO CO14073110A patent/CO6930306A2/en unknown
- 2014-04-04 CR CR20140159A patent/CR20140159A/en unknown
- 2014-04-04 CR CR20140158A patent/CR20140158A/en unknown
- 2014-04-04 CO CO14073108A patent/CO6930351A2/en unknown
-
2015
- 2015-01-06 HK HK15100076.0A patent/HK1199656A1/en not_active IP Right Cessation
- 2015-01-20 HK HK15100624.7A patent/HK1200207A1/en not_active IP Right Cessation
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