PE20142141A1 - Linea de proceso para la produccion de particulas criodesecadas - Google Patents

Linea de proceso para la produccion de particulas criodesecadas

Info

Publication number
PE20142141A1
PE20142141A1 PE2014000480A PE2014000480A PE20142141A1 PE 20142141 A1 PE20142141 A1 PE 20142141A1 PE 2014000480 A PE2014000480 A PE 2014000480A PE 2014000480 A PE2014000480 A PE 2014000480A PE 20142141 A1 PE20142141 A1 PE 20142141A1
Authority
PE
Peru
Prior art keywords
particles
process line
production
spray chamber
criodessed
Prior art date
Application number
PE2014000480A
Other languages
English (en)
Inventor
Bernhard Luy
Matthias Plitzko
Manfred Struschka
Original Assignee
Sanofi Pasteur Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Sa filed Critical Sanofi Pasteur Sa
Publication of PE20142141A1 publication Critical patent/PE20142141A1/es

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)

Abstract

REFERIDA A UNA LINEA DE PROCESO PARA LA PRODUCCION DE PARTICULAS CRIODISECADAS BAJO CONDICIONES CERRADAS, DONDE LA LINEA DE PROCESO COMPRENDE: UNA CAMARA DE ASPERSION PARA LA GENERACION DE GOTITAS Y CRIOCONGELACION DE LAS MISMAS PARA FORMAR PARTICULAS Y UN CRIODESECADOR, EN DONDE EL PRODUCTO SE TRANSFIERE DESDE LA CAMARA DE ASPERSION HASTA EL CRIODESECADOR; LA CAMARA DE ASPERSION SE ADAPTA PARA LA SEPARACION DE LAS GOTITAS DE LIQUIDO DE CUALQUIER CIRCUITO DE ENFRIAMIENTO PARA LA CRIOCONGELACION DE LAS PARTICULAS YA QUE COMPRENDE UNA PARED INTERIOR ENFRIADA COMO EL UNICO COMPONENTE DE ENFRIAMIENTO, PARA EVITAR EL FLUJO DE ENFRIAMIENTO CONTRA O CONCURRENTE
PE2014000480A 2011-10-05 2012-10-04 Linea de proceso para la produccion de particulas criodesecadas PE20142141A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11008057.9A EP2578974A1 (en) 2011-10-05 2011-10-05 Process line for the production of freeze-dried particles

Publications (1)

Publication Number Publication Date
PE20142141A1 true PE20142141A1 (es) 2015-01-04

Family

ID=46980888

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2014000479A PE20141979A1 (es) 2011-10-05 2012-10-04 Linea de proceso para la produccion de particulas criodesecadas
PE2014000480A PE20142141A1 (es) 2011-10-05 2012-10-04 Linea de proceso para la produccion de particulas criodesecadas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2014000479A PE20141979A1 (es) 2011-10-05 2012-10-04 Linea de proceso para la produccion de particulas criodesecadas

Country Status (25)

Country Link
US (2) US9920989B2 (es)
EP (4) EP2578974A1 (es)
JP (2) JP5728135B2 (es)
KR (2) KR101512608B1 (es)
CN (2) CN103917841B (es)
AU (2) AU2012320854B2 (es)
BR (2) BR112014008001B1 (es)
CA (2) CA2849802C (es)
CO (2) CO6930306A2 (es)
CR (2) CR20140158A (es)
DK (2) DK2766682T3 (es)
EA (2) EA027630B1 (es)
ES (2) ES2608478T3 (es)
HK (2) HK1199656A1 (es)
HU (2) HUE029973T2 (es)
IL (2) IL231853A0 (es)
IN (2) IN2014CN02440A (es)
MX (2) MX359904B (es)
MY (2) MY151369A (es)
PE (2) PE20141979A1 (es)
PL (2) PL2764309T3 (es)
SG (2) SG11201400640VA (es)
UA (2) UA111858C2 (es)
WO (2) WO2013050156A1 (es)
ZA (1) ZA201401930B (es)

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EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer
UA111631C2 (uk) 2011-10-06 2016-05-25 Санофі Пастер Са Нагрівальний пристрій для роторної барабанної ліофільної сушарки
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AU2015293983B2 (en) * 2014-07-21 2017-02-09 Sanofi Pasteur Sa Liquid feeding device for the generation of droplets
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
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US9739532B2 (en) * 2015-02-04 2017-08-22 Steven F. Baugh Botanical freeze drying system and method
EP3303958B1 (en) * 2015-06-01 2019-10-09 IMA Life North America Inc. Bulk freeze drying using spray freezing and agitated drying with heating
RU2615553C1 (ru) * 2015-10-15 2017-04-05 Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" Способ и устройство непрерывной сублимационной сушки жидких продуктов
EP3167877A1 (en) 2015-11-12 2017-05-17 Bayer Pharma Aktiengesellschaft Method for the production of freeze-dried pellets comprising factor viii
CN106705574A (zh) * 2015-11-17 2017-05-24 上海东富龙科技股份有限公司 一种固体制剂制造设备和方法
JP6666535B2 (ja) * 2016-01-05 2020-03-18 株式会社あい・あいエナジーアソシエイツ 液体の凍結乾燥装置及び凍結乾燥方法
CN105674691B (zh) * 2016-04-01 2017-11-21 苏州大学 用于收集喷雾冷冻冰球颗粒的双密封式设备及其收集方法
US10369077B2 (en) * 2017-05-31 2019-08-06 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using the same
US10507165B2 (en) 2017-05-31 2019-12-17 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using same
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EP3473959B1 (de) * 2017-10-20 2020-02-12 Martin Christ Gefriertrocknungsanlagen GmbH Verfahren zur druckbasierten ermittlung eines produktparameters in einem gefriertrockner, gefriertrockner und softwareprodukt
KR102450460B1 (ko) * 2017-12-29 2022-09-30 아주대학교산학협력단 초음파 분무기를 이용한 미립구 약제의 양산 시스템
JP7038435B2 (ja) * 2018-03-13 2022-03-18 株式会社プリス 噴霧凍結造粒乾燥粉体製造装置及び噴霧凍結造粒乾燥粉体製造システム
CN111065874B (zh) * 2018-06-08 2020-12-29 株式会社爱发科 真空冻结干燥装置和真空冻结干燥方法
CA3105261A1 (en) 2018-07-05 2020-01-09 Bayer Aktiengesellschaft Method for the production of freeze-dried pellets comprising an anti-coagulation factor xia (fxia) antibody
WO2020161863A1 (ja) * 2019-02-07 2020-08-13 株式会社アルバック 真空凍結乾燥方法及び真空凍結乾燥装置
US11243029B2 (en) * 2019-04-26 2022-02-08 Purdue Research Foundation Process monitoring and control for lyophilization using a wireless sensor network
CN111207564B (zh) * 2019-09-30 2022-01-04 中国科学院上海硅酸盐研究所 一种冷冻干燥系统及方法
JP6777350B1 (ja) 2020-05-18 2020-10-28 株式会社エムアイアイ 真空凍結乾燥装置及び真空凍結乾燥方法
TW202202792A (zh) 2020-05-18 2022-01-16 日商Ｍｉｉ股份有限公司 真空凍結乾燥裝置及真空凍結乾燥方法
JP6887050B1 (ja) * 2020-08-07 2021-06-16 株式会社アルバック 真空凍結乾燥方法および真空凍結乾燥装置
US20230168034A1 (en) * 2020-08-07 2023-06-01 Ulvac, Inc. Vacuum freeze-drying method, injection nozzle for a vacuum freeze-drying apparatus, and vacuum freeze-drying apparatus
US11874060B2 (en) 2020-11-16 2024-01-16 Sublime Stericeuticals Corporation Continuous throughput lyophilizer-powder filler within a sterile boundary
JP7085088B1 (ja) * 2021-08-03 2022-06-16 株式会社エムアイアイ 凍結乾燥物
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US20230122361A1 (en) * 2021-10-20 2023-04-20 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods
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EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
UA111631C2 (uk) 2011-10-06 2016-05-25 Санофі Пастер Са Нагрівальний пристрій для роторної барабанної ліофільної сушарки
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Also Published As

Publication number Publication date
MY151369A (en) 2014-05-16
EP3211355A1 (en) 2017-08-30
PL2764309T3 (pl) 2017-03-31
EA201490723A1 (ru) 2014-08-29
SG11201400641QA (en) 2014-08-28
MX341894B (es) 2016-09-07
EP2766682A1 (en) 2014-08-20
CA2849802A1 (en) 2013-04-11
JP5728135B2 (ja) 2015-06-03
CA2849799C (en) 2015-12-08
BR112014008001A2 (pt) 2017-04-11
CO6930351A2 (es) 2014-04-28
JP2014530685A (ja) 2014-11-20
CN103917841B (zh) 2015-07-08
US9920989B2 (en) 2018-03-20
EA027630B1 (ru) 2017-08-31
ES2608427T3 (es) 2017-04-10
DK2764309T3 (en) 2017-01-09
CO6930306A2 (es) 2014-04-28
JP5766361B2 (ja) 2015-08-19
EA201490719A1 (ru) 2014-09-30
MX359904B (es) 2018-10-16
HK1200207A1 (en) 2015-07-31
BR112014007862B1 (pt) 2021-01-19
BR112014007862A2 (pt) 2017-04-18
WO2013050162A1 (en) 2013-04-11
CA2849799A1 (en) 2013-04-11
JP2014530061A (ja) 2014-11-17
MX2014004041A (es) 2014-08-01
PE20141979A1 (es) 2014-12-19
US10006706B2 (en) 2018-06-26
WO2013050156A1 (en) 2013-04-11
KR20140088113A (ko) 2014-07-09
ES2608478T3 (es) 2017-04-11
AU2012320854A1 (en) 2014-05-15
HUE029973T2 (en) 2017-04-28
IN2014CN02440A (es) 2015-06-19
AU2012320848B8 (en) 2015-03-05
CN103917841A (zh) 2014-07-09
WO2013050156A8 (en) 2013-06-13
EP2578974A1 (en) 2013-04-10
US20140245629A1 (en) 2014-09-04
EP2766682B1 (en) 2016-11-23
CR20140159A (es) 2014-10-30
IL231849A0 (en) 2014-05-28
MX2014004000A (es) 2014-07-22
CA2849802C (en) 2015-12-08
UA111859C2 (uk) 2016-06-24
KR101512608B1 (ko) 2015-04-15
AU2012320848B2 (en) 2015-02-26
KR101552804B1 (ko) 2015-09-11
CR20140158A (es) 2014-10-30
MY152319A (en) 2014-09-08
SG11201400640VA (en) 2014-06-27
DK2766682T3 (en) 2017-01-09
CN103917842B (zh) 2015-08-05
IL231853A0 (en) 2014-05-28
ZA201401930B (en) 2015-02-25
US20140230266A1 (en) 2014-08-21
HUE030970T2 (en) 2017-06-28
CN103917842A (zh) 2014-07-09
BR112014008001B1 (pt) 2021-01-19
PL2766682T3 (pl) 2017-03-31
EP2764309A1 (en) 2014-08-13
EP2764309B1 (en) 2016-11-23
HK1199656A1 (en) 2015-07-10
AU2012320854B2 (en) 2015-02-19
AU2012320848A1 (en) 2014-05-15
UA111858C2 (uk) 2016-06-24
KR20140088112A (ko) 2014-07-09
IN2014CN02407A (es) 2015-06-19
EA027602B1 (ru) 2017-08-31

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