PL2553113T3 - Sposób wytwarzania L-ornityny przy zastosowaniu bakterii nadeksprymujących LysE - Google Patents

Sposób wytwarzania L-ornityny przy zastosowaniu bakterii nadeksprymujących LysE

Info

Publication number
PL2553113T3
PL2553113T3 PL11710196T PL11710196T PL2553113T3 PL 2553113 T3 PL2553113 T3 PL 2553113T3 PL 11710196 T PL11710196 T PL 11710196T PL 11710196 T PL11710196 T PL 11710196T PL 2553113 T3 PL2553113 T3 PL 2553113T3
Authority
PL
Poland
Prior art keywords
lyse
ornithine
employing
producing
overexpressing bacteria
Prior art date
Application number
PL11710196T
Other languages
English (en)
Inventor
Wilfried Claes
Robert Gerstmeir
Original Assignee
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Operations Gmbh filed Critical Evonik Operations Gmbh
Publication of PL2553113T3 publication Critical patent/PL2553113T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL11710196T 2010-03-30 2011-03-24 Sposób wytwarzania L-ornityny przy zastosowaniu bakterii nadeksprymujących LysE PL2553113T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102010003419.3A DE102010003419B4 (de) 2010-03-30 2010-03-30 Verfahren zur fermentativen Herstellung von L-Ornithin
PCT/EP2011/054541 WO2011124477A2 (de) 2010-03-30 2011-03-24 VERFAHREN ZUR HERSTELLUNG VON L- ORNITHIN UNTER VERWENDUNG VON LysE ÜBEREXPRIMIERENDEN BAKTERIEN
EP11710196.4A EP2553113B1 (de) 2010-03-30 2011-03-24 Verfahren zur herstellung von l-ornithin unter verwendung von lyse überexprimierenden bakterien

Publications (1)

Publication Number Publication Date
PL2553113T3 true PL2553113T3 (pl) 2022-03-21

Family

ID=44625512

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11710196T PL2553113T3 (pl) 2010-03-30 2011-03-24 Sposób wytwarzania L-ornityny przy zastosowaniu bakterii nadeksprymujących LysE

Country Status (15)

Country Link
US (2) US8741608B2 (pl)
EP (1) EP2553113B1 (pl)
JP (1) JP5855084B2 (pl)
KR (1) KR101782666B1 (pl)
CN (1) CN102947460B (pl)
BR (1) BR112012024799B1 (pl)
CA (1) CA2794974C (pl)
DE (1) DE102010003419B4 (pl)
DK (1) DK2553113T3 (pl)
ES (1) ES2900273T3 (pl)
PL (1) PL2553113T3 (pl)
RU (1) RU2571932C2 (pl)
SG (1) SG183922A1 (pl)
UA (1) UA109898C2 (pl)
WO (1) WO2011124477A2 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
KR101526047B1 (ko) * 2013-04-26 2015-06-04 상지대학교산학협력단 아미노트랜스퍼라제 활성 강화를 통하여 ｌ-오르니틴 생산능이 향상된 미생물 및 이를 이용한 ｌ-오르니틴의 제조방법
EP2811028B1 (de) 2013-06-03 2017-02-01 Evonik Degussa GmbH Verfahren zur Herstellung von L-Valin unter Verwendung rekombinanter Corynebakterien enthaltend das durch Propionat induzierbare ilvBN-Operon
JP2017131111A (ja) * 2014-06-03 2017-08-03 味の素株式会社 Ｌ−アミノ酸の製造法
CN104031934A (zh) * 2014-06-05 2014-09-10 江南大学 过量共表达磷酸果糖激酶和丙酮酸激酶提高钝齿棒杆菌精氨酸产量
US10544435B2 (en) * 2015-03-12 2020-01-28 Chrysea Limited L-ornithine production in eukaryotic cells
PT3445406T (pt) * 2016-04-20 2021-08-30 Fundacion Instituto De Investig Sanitaria Fundacion Jimenez Diaz Composições e métodos para potenciar a expressão de gene de pklr
CN106148440B (zh) * 2016-08-10 2021-12-07 洛阳华荣生物技术有限公司 发酵法生产胍基丁胺
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN107236769B (zh) * 2017-06-26 2021-01-26 南京工业大学 一种利用膜循环生物反应器分阶段制备l-鸟氨酸和丁二酸的方法
EP3456833A1 (en) * 2017-09-18 2019-03-20 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
EP3467099A1 (en) 2017-10-05 2019-04-10 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
JP7403461B2 (ja) 2017-10-16 2023-12-22 セントロ デ インベスティガシオンス エネルジェチカス メディオアンビエンタゥス イェ テクノロジカス オー．エイ． エム．ピー． ピルビン酸キナーゼ欠損症を治療するためのｐｋｌｒ送達用レンチウイルスベクター
CN107739728A (zh) * 2017-10-19 2018-02-27 江南大学 一种高效生产氨基葡萄糖的重组大肠杆菌及其应用
CN109161507B (zh) * 2018-09-27 2020-07-14 南京工业大学 一种高产l-鸟氨酸的谷氨酸棒杆菌及其应用
CN110079566B (zh) * 2019-05-16 2020-08-04 黑龙江伊品生物科技有限公司 用改变ppc启动子的细菌发酵生产L-赖氨酸的方法
CN110195087B (zh) * 2019-05-16 2020-12-01 黑龙江伊品生物科技有限公司 用改变ppc基因的细菌发酵生产L-赖氨酸的方法
KR102139806B1 (ko) * 2020-02-13 2020-07-30 씨제이제일제당 (주) 변이형 LysE를 포함하는 미생물, 및 이를 이용한 L-아미노산 생산 방법
CN111334535B (zh) * 2020-03-26 2021-11-30 廊坊梅花生物技术开发有限公司 生产l-氨基酸的重组菌株及其应用
CN113201538B (zh) * 2021-01-12 2022-09-16 中国科学院天津工业生物技术研究所 具有启动子活性的多核苷酸及其在生产目标化合物中的用途
CN115490761B (zh) 2021-11-01 2023-06-09 中国科学院天津工业生物技术研究所 基于赖氨酸外排蛋白构建的重组微生物及生产赖氨酸的方法
CN114107158B (zh) * 2021-12-22 2022-07-26 广东省科学院生物与医学工程研究所 一种高产高纯度异麦芽酮糖的重组谷氨酸棒杆菌及其应用
CN116622599A (zh) * 2022-02-14 2023-08-22 廊坊梅花生物技术开发有限公司 高产苏氨酸菌株的构建方法
KR20230167496A (ko) * 2022-06-02 2023-12-11 씨제이제일제당 (주) L-오르니틴 생산능을 가지는 미생물 및 이를 이용한 l-오르니틴 생산방법

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US366072A (en) 1887-07-05 Harry g-
US2988489A (en) 1957-09-19 1961-06-13 Kyowa Hakko Kogyo Kk Method of producing l-ornithine by fermentation
JPS427767Y1 (pl) 1965-01-11 1967-04-18
JPS4310996Y1 (pl) 1965-12-28 1968-05-13
GB1140827A (en) 1966-10-06 1969-01-22 Kyowa Hakko Kogyo Kk Fermentative preparation of l-ornithine
JPS463194Y1 (pl) 1967-06-29 1971-02-03
US3668072A (en) 1969-01-02 1972-06-06 Chugai Pharmaceutical Co Ltd Fermentation process for the production of l-ornithine
JPS5324096A (en) 1976-08-19 1978-03-06 Kyowa Hakko Kogyo Co Ltd Preparation of l-ornithine by fermentation
JPS5927691B2 (ja) 1980-08-28 1984-07-07 株式会社丸山製作所 多槽タンク成形方法
JPS61119194A (ja) 1984-11-15 1986-06-06 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−オルニチンの製造法
US4990487A (en) 1988-03-11 1991-02-05 The University Of Tokyo Superconductive optoelectronic devices
US4889942A (en) 1989-04-12 1989-12-26 Dow Corning Corporation Process for synthesis of acylamino organosilicon compounds
JP2817185B2 (ja) 1989-04-20 1998-10-27 味の素株式会社 発酵法によるｌ―オルニチンの製造法
JPH03195494A (ja) 1989-12-26 1991-08-27 Toray Ind Inc 発酵法によるｌ―プロリンの製造方法
ATE116285T1 (de) 1990-09-28 1995-01-15 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von kristallen eines salzes von sauerer aminosäure und basischer aminosäure.
US5693781A (en) 1991-06-03 1997-12-02 Mitsubishi Chemical Corporation Promoter DNA fragment from coryneform bacteria
JP3195494B2 (ja) 1994-06-10 2001-08-06 スター精密株式会社 流体加圧装置
KR0161147B1 (ko) 1995-05-12 1998-11-16 김은영 오르니틴의 제조방법
DE19548222A1 (de) 1995-12-22 1997-06-26 Forschungszentrum Juelich Gmbh Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern
US6861246B2 (en) 1999-07-07 2005-03-01 Degussa Ag L-lysine-producing corynebacteria and process for the preparation of lysine
MXPA02001174A (es) 1999-08-02 2002-07-30 Archer Daniels Midland Co Ingenieria metabolica de la produccion de aminoacidos.
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
US6562601B2 (en) 2000-08-31 2003-05-13 Degussa Ag Fermentation process for the preparation of L-threonine
DE10047865A1 (de) 2000-09-27 2002-04-18 Degussa Neue für das deaD-Gen kodierende Nukleotidsequenzen
DE60232120D1 (de) 2001-06-12 2009-06-10 Ajinomoto Kk Verfahren zur Herstellung von L-Lysin oder L-Arginin unter Verwendung methanolassimilierender Bakterien
US7252978B2 (en) * 2001-07-25 2007-08-07 Ajinomoto Co., Inc. Method for producing L-arginine
AU2002355462A1 (en) 2001-08-06 2003-02-24 Degussa Ag Coryneform bacteria which produce chemical compounds ii
US7160711B2 (en) 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
AU2002325923A1 (en) 2001-08-06 2003-05-19 Degussa Ag Production of l-lysine by genetically modified corynebacterium glutamicum strains
WO2005021772A1 (en) 2003-08-29 2005-03-10 Degussa Ag Process for the preparation of l-lysine
DE10359660A1 (de) 2003-12-18 2005-07-28 Basf Ag Psod-Expressionseinheiten
PL1664318T3 (pl) * 2004-01-30 2010-03-31 Ajinomoto Kk Mikroorganizm wytwarzający L-aminokwas i sposób wytwarzania L-aminokwasu
CN1594282A (zh) 2004-07-15 2005-03-16 武汉武大弘元股份有限公司 L－鸟氨酸盐酸盐的制备方法
KR100589121B1 (ko) 2004-08-20 2006-06-14 주식회사 엠에이치투 바이오케미칼 효소반응을 이용한 ｌ-오르니틴의 제조방법
BRPI0516176B1 (pt) * 2004-09-28 2020-12-29 Kyowa Hakko Bio Co., Ltd. Polipeptídeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou lcitrulina
PL2818556T3 (pl) 2004-10-07 2023-07-17 Ajinomoto Co., Inc. Sposób wytwarzania zasadowej substancji
DE102004061846A1 (de) 2004-12-22 2006-07-13 Basf Ag Mehrfachpromotoren
DE102005013676A1 (de) 2005-03-24 2006-09-28 Degussa Ag Allele des zwf-Gens aus coryneformen Bakterien
EP1995322B1 (en) 2006-03-15 2017-11-22 Kyowa Hakko Bio Co., Ltd. Methods for purifying amino acids
EP2386650B1 (en) 2006-04-07 2013-07-03 Evonik Degussa GmbH Method for producing L-amino acids using the gap promoter
EP1881076A1 (en) 2006-07-17 2008-01-23 Evonik Degussa GmbH Method for producing L-amino acids
EP2082045B1 (en) 2006-10-24 2015-03-18 Basf Se Method of reducing gene expression using modified codon usage
KR100789274B1 (ko) 2007-01-15 2008-01-02 씨제이 주식회사 코리네박테리움 글루타미쿰에서 유래한 신규한 프로모터핵산 분자, 그 프로모터를 포함하는 재조합 벡터, 그재조합 벡터를 포함하는 숙주 세포 및 그 숙주 세포를이용하여 유전자를 발현하는 방법
CN101323866A (zh) * 2007-06-14 2008-12-17 上海聚瑞生物技术有限公司 一种微生物发酵生产l-鸟氨酸的方法
KR100898246B1 (ko) 2007-08-17 2009-05-18 씨제이제일제당 (주) 신규한 코리네박테리움 글루타미쿰 프로모터
KR20110008065A (ko) 2008-04-30 2011-01-25 에보니크 데구사 게엠베하 이소시트레이트 데하이드로게나제 활성이 감소된 미생물을 사용한 메티오닌 생산 방법

Also Published As

Publication number Publication date
WO2011124477A2 (de) 2011-10-13
KR101782666B1 (ko) 2017-09-27
DE102010003419B4 (de) 2019-09-12
JP5855084B2 (ja) 2016-02-09
DE102010003419A1 (de) 2012-04-12
RU2012145953A (ru) 2014-05-10
UA109898C2 (uk) 2015-10-26
WO2011124477A3 (de) 2012-01-12
SG183922A1 (en) 2012-10-30
US8741608B2 (en) 2014-06-03
BR112012024799B1 (pt) 2020-11-17
CN102947460B (zh) 2015-12-02
EP2553113A2 (de) 2013-02-06
RU2571932C2 (ru) 2015-12-27
EP2553113B1 (de) 2021-11-03
US8951759B2 (en) 2015-02-10
JP2013524781A (ja) 2013-06-20
DK2553113T3 (da) 2022-01-24
US20140206068A1 (en) 2014-07-24
CA2794974C (en) 2018-03-20
KR20130020774A (ko) 2013-02-28
US20110244529A1 (en) 2011-10-06
ES2900273T3 (es) 2022-03-16
BR112012024799A2 (pt) 2017-12-12
CN102947460A (zh) 2013-02-27
CA2794974A1 (en) 2011-10-13

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