AU2002325923A1 - Production of l-lysine by genetically modified corynebacterium glutamicum strains - Google Patents
Production of l-lysine by genetically modified corynebacterium glutamicum strainsInfo
- Publication number
- AU2002325923A1 AU2002325923A1 AU2002325923A AU2002325923A AU2002325923A1 AU 2002325923 A1 AU2002325923 A1 AU 2002325923A1 AU 2002325923 A AU2002325923 A AU 2002325923A AU 2002325923 A AU2002325923 A AU 2002325923A AU 2002325923 A1 AU2002325923 A1 AU 2002325923A1
- Authority
- AU
- Australia
- Prior art keywords
- lysine
- production
- genetically modified
- corynebacterium glutamicum
- glutamicum strains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30987801P | 2001-08-06 | 2001-08-06 | |
US60/309,878 | 2001-08-06 | ||
PCT/EP2002/008464 WO2003040373A2 (en) | 2001-08-06 | 2002-07-30 | Production of l-lysine by genetically modified corynebacterium glutamicum strains |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002325923A1 true AU2002325923A1 (en) | 2003-05-19 |
Family
ID=23200067
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002325923A Abandoned AU2002325923A1 (en) | 2001-08-06 | 2002-07-30 | Production of l-lysine by genetically modified corynebacterium glutamicum strains |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1414970A2 (en) |
CN (1) | CN100554426C (en) |
AU (1) | AU2002325923A1 (en) |
BR (1) | BR0211723A (en) |
CA (1) | CA2455878A1 (en) |
WO (1) | WO2003040373A2 (en) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7160711B2 (en) | 2001-08-06 | 2007-01-09 | Degussa Ag | Coryneform bacteria which produce chemical compounds I |
US6844176B1 (en) | 2001-10-16 | 2005-01-18 | Degussa Ag | Alleles of the lysC gene from corynebacteria |
DE10359594A1 (en) | 2003-12-18 | 2005-07-28 | Basf Ag | PEF TU-expression units |
DE102004035067A1 (en) * | 2004-07-20 | 2006-02-16 | Basf Ag | P1-35 expression units |
DE102005013676A1 (en) | 2005-03-24 | 2006-09-28 | Degussa Ag | Alleles of the zwf gene from coryneform bacteria |
DE102005023829A1 (en) | 2005-05-24 | 2006-11-30 | Degussa Ag | Alleles of the opcA gene from coryneform bacteria |
DE102005047596A1 (en) | 2005-10-05 | 2007-04-12 | Degussa Ag | Process for the fermentative production of L-amino acids using coryneform bacteria |
DE102006026328A1 (en) * | 2006-06-02 | 2008-01-03 | Evonik Degussa Gmbh | Process for the preparation of a feed additive containing L-lysine |
KR100830289B1 (en) * | 2007-01-18 | 2008-05-16 | 씨제이제일제당 (주) | Corynebacterium glutamicum variety producing l-arginine and method for fabricating the same |
DE102007005072A1 (en) | 2007-02-01 | 2008-08-07 | Evonik Degussa Gmbh | Process for the fermentative production of cadaverine |
JP2011067095A (en) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | Method for producing target substance by fermentation process |
KR100987281B1 (en) * | 2008-01-31 | 2010-10-12 | 씨제이제일제당 (주) | Enhanced promoter and method for producing L-lysine using the same |
DE102008001874A1 (en) | 2008-05-20 | 2009-11-26 | Evonik Degussa Gmbh | Process for the preparation of L-amino acids |
DE102009030342A1 (en) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Process for the fermentative production of organic chemical compounds |
DE102010003419B4 (en) | 2010-03-30 | 2019-09-12 | Evonik Degussa Gmbh | Process for the fermentative production of L-ornithine |
DE102010025124A1 (en) | 2010-06-25 | 2011-12-29 | Forschungszentrum Jülich GmbH | Process for the preparation of D-amino acids, microorganism, and vector |
EP2479279A1 (en) | 2011-01-20 | 2012-07-25 | Evonik Degussa GmbH | Method for producing sulphuric amino acids by means of fermentation |
US9745608B2 (en) | 2011-02-22 | 2017-08-29 | Basf Se | Processes and recombinant microorganisms for the production of cadaverine |
DE102011006716A1 (en) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Microorganism and process for the fermentative production of an organic chemical compound |
JP2014131487A (en) | 2011-04-18 | 2014-07-17 | Ajinomoto Co Inc | Method for producing l-cysteine |
DE102011118019A1 (en) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Variants of the promoter of the glyceraldehyde-3-phosphate dehydrogenase-encoding gap gene |
CN103946372B (en) | 2011-11-02 | 2016-06-08 | 味之素株式会社 | For method for secretory generation of protein |
PE20141569A1 (en) | 2011-11-11 | 2014-11-08 | Ajinomoto Kk | METHOD FOR PRODUCING A TARGET SUBSTANCE BY FERMENTATION |
EP2628792A1 (en) | 2012-02-17 | 2013-08-21 | Evonik Industries AG | Cell with reduced ppGppase activity |
EP2631298A1 (en) | 2012-02-22 | 2013-08-28 | Evonik Industries AG | Biotechnological method for producing butanol and butyric acid |
WO2013160124A1 (en) | 2012-04-27 | 2013-10-31 | Evonik Industries Ag | Feedback-resistant alpha-isopropylmalate synthases |
EP2674489A1 (en) | 2012-06-15 | 2013-12-18 | Evonik Industries AG | Biotechnological 2-hydroxyisobutyric acid production |
EP2700715B1 (en) | 2012-08-20 | 2018-07-25 | Evonik Degussa GmbH | Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family by means of fermentation |
DE102012016716A1 (en) | 2012-08-22 | 2014-02-27 | Forschungszentrum Jülich GmbH | A process for the preparation of vectors comprising a gene coding for an enzyme which has been reduced or eliminated in its feedback inhibition and the use thereof for the production of amino acids and nucleotides |
EP2762571A1 (en) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Microorganism and method for the production of amino acids by fermentation |
PL2811028T3 (en) | 2013-06-03 | 2017-07-31 | Evonik Degussa Gmbh | Process for producing L-valine employing recombinant Corynebacteria comprising the propionate-inducible ilvBN operon |
CN103374540B (en) * | 2013-08-13 | 2015-04-22 | 廊坊梅花生物技术开发有限公司 | Corynebacterium glutamicum and application thereof |
EP2940039A1 (en) | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Method for the production of l-amino acids in coryne bacteria using a glycine splitting system |
DE102014208199A1 (en) | 2014-04-30 | 2015-11-05 | Evonik Degussa Gmbh | Process for the production of L-amino acids using an alkaliphilic bacterium |
ES2778037T3 (en) | 2014-04-30 | 2020-08-07 | Evonik Operations Gmbh | Procedure for the production of L-amino acids using alkaliphilic bacteria |
EP2940144A1 (en) | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Method for the production of l-lysine using an alkaliphilic bacterium |
US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
KR20180084756A (en) | 2015-12-07 | 2018-07-25 | 지머젠 인코포레이티드 | Promoter from Corynebacterium glutamicum |
KR101756338B1 (en) * | 2016-01-15 | 2017-07-10 | 고려대학교 산학협력단 | Variant Microorganism for Producing L-Cystein and Method for Preparing L-Cystein Using thereof |
CN105838740B (en) * | 2016-05-03 | 2020-11-06 | 湖北大学 | Method for preparing nano red element selenium by using tea tree endophytic asplenium |
EP3478845A4 (en) | 2016-06-30 | 2019-07-31 | Zymergen, Inc. | Methods for generating a glucose permease library and uses thereof |
US10544390B2 (en) | 2016-06-30 | 2020-01-28 | Zymergen Inc. | Methods for generating a bacterial hemoglobin library and uses thereof |
MX2019000075A (en) * | 2016-07-08 | 2019-05-02 | Metabolic Explorer Sa | Method for the fermentative production of molecules of interest by microorganisms comprising genes coding sugar phosphotransferase system (pts). |
CN106635944A (en) * | 2016-12-29 | 2017-05-10 | 廊坊梅花生物技术开发有限公司 | Glutamic acid corynebacterium and construction method and application thereof |
WO2018226964A2 (en) | 2017-06-07 | 2018-12-13 | Zymergen Inc. | Promoters from corynebacterium glutamicum and uses thereof in regulating ancillary gene expression |
EP3415622A1 (en) | 2017-06-14 | 2018-12-19 | Evonik Degussa GmbH | Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases |
KR102011994B1 (en) * | 2017-06-30 | 2019-08-20 | 씨제이제일제당 주식회사 | Novel aspartokinase variant and method of producing L-amino acid using thereof |
CN109536428B (en) * | 2018-12-07 | 2022-08-30 | 武汉远大弘元股份有限公司 | Genetically engineered bacterium for producing L-isoleucine and construction method and application thereof |
CN111471638B (en) * | 2020-05-22 | 2021-11-23 | 江南大学 | Construction and application of corynebacterium glutamicum mutant strain capable of producing L-homoserine |
EP4105332A4 (en) * | 2021-05-07 | 2022-12-28 | CJ Cheiljedang Corporation | Novel promoter and use thereof |
CN114181288B (en) * | 2022-02-17 | 2022-05-03 | 北京中科伊品生物科技有限公司 | Process for producing L-valine, gene used therefor and protein encoded by the gene |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19931317A1 (en) * | 1999-07-07 | 2001-01-11 | Degussa | L-lysine-producing coryneform bacteria and method for producing L-lysine |
US6893848B1 (en) * | 1999-04-19 | 2005-05-17 | Kyowa Hakko Kogyo Co., Ltd. | Desensitized aspartokinase |
DE19950409A1 (en) * | 1999-10-20 | 2001-04-26 | Degussa | New nucleotide sequences coding for the pck gene |
JP4623825B2 (en) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | Novel polynucleotide |
-
2002
- 2002-07-30 BR BR0211723-1A patent/BR0211723A/en not_active Application Discontinuation
- 2002-07-30 AU AU2002325923A patent/AU2002325923A1/en not_active Abandoned
- 2002-07-30 CA CA002455878A patent/CA2455878A1/en not_active Abandoned
- 2002-07-30 EP EP02760293A patent/EP1414970A2/en not_active Withdrawn
- 2002-07-30 WO PCT/EP2002/008464 patent/WO2003040373A2/en not_active Application Discontinuation
- 2002-07-30 CN CNB028154460A patent/CN100554426C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN100554426C (en) | 2009-10-28 |
BR0211723A (en) | 2004-09-21 |
CA2455878A1 (en) | 2003-05-15 |
WO2003040373A2 (en) | 2003-05-15 |
WO2003040373A3 (en) | 2003-12-18 |
CN1539015A (en) | 2004-10-20 |
EP1414970A2 (en) | 2004-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |