PL113999B1 - Process for preparing novel derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones - Google Patents

Process for preparing novel derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones Download PDF

Info

Publication number
PL113999B1
PL113999B1 PL1978207192A PL20719278A PL113999B1 PL 113999 B1 PL113999 B1 PL 113999B1 PL 1978207192 A PL1978207192 A PL 1978207192A PL 20719278 A PL20719278 A PL 20719278A PL 113999 B1 PL113999 B1 PL 113999B1
Authority
PL
Poland
Prior art keywords
formula
pyrido
dihydro
benzodiazepin
ethanol
Prior art date
Application number
PL1978207192A
Other languages
English (en)
Polish (pl)
Other versions
PL207192A1 (pl
Inventor
Shumitsuto Gyuntaa
Reitorudo Matsutoyasu
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2724478A external-priority patent/DE2724478C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of PL207192A1 publication Critical patent/PL207192A1/xx
Publication of PL113999B1 publication Critical patent/PL113999B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL1978207192A 1977-05-31 1978-05-30 Process for preparing novel derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones PL113999B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2724478A DE2724478C2 (de) 1977-05-31 1977-05-31 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
PL207192A1 PL207192A1 (pl) 1979-04-23
PL113999B1 true PL113999B1 (en) 1981-01-31

Family

ID=6010286

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1978207192A PL113999B1 (en) 1977-05-31 1978-05-30 Process for preparing novel derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones

Country Status (30)

Country Link
US (1) US4210648A (en, 2012)
JP (1) JPS543092A (en, 2012)
AT (1) AT361929B (en, 2012)
AU (1) AU516712B2 (en, 2012)
BE (1) BE867639A (en, 2012)
BG (1) BG28712A3 (en, 2012)
CA (1) CA1081220A (en, 2012)
CH (1) CH637956A5 (en, 2012)
CS (1) CS202600B2 (en, 2012)
DD (1) DD135490A5 (en, 2012)
DK (1) DK148233C (en, 2012)
ES (1) ES470269A1 (en, 2012)
FI (1) FI63233C (en, 2012)
FR (1) FR2392991A1 (en, 2012)
GB (1) GB1581500A (en, 2012)
GR (1) GR64535B (en, 2012)
HK (1) HK19381A (en, 2012)
HU (1) HU180540B (en, 2012)
IE (1) IE46909B1 (en, 2012)
IL (1) IL54815A (en, 2012)
MY (1) MY8100362A (en, 2012)
NL (1) NL7805848A (en, 2012)
NO (1) NO149065C (en, 2012)
NZ (1) NZ187428A (en, 2012)
PL (1) PL113999B1 (en, 2012)
PT (1) PT68114A (en, 2012)
SE (1) SE437831B (en, 2012)
SU (1) SU797578A3 (en, 2012)
YU (1) YU129478A (en, 2012)
ZA (1) ZA783086B (en, 2012)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
GR72993B (en, 2012) * 1980-01-24 1984-01-25 Crc Ricerca Chim
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3212794A1 (de) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5264432A (en) * 1989-07-31 1993-11-23 Arzneimittelwerk Dresden G.M.B.H 5-(1-aminoacyl)-5,10-dihydro-11H-dibenzo[b,e](1,4)diazepin-11-ones
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3930262A1 (de) * 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
JP5020819B2 (ja) 2004-07-16 2012-09-05 プロテオシス・アーゲー 細胞保護剤としての、ｐａｒｐ及びｓｉｒ調節活性を有するムスカリンアンタゴニスト
WO2010081825A2 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as an agent in cancer treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
US3691152A (en) * 1971-03-10 1972-09-12 Texaco Inc Hydrodesulfurization and blending of residue-containing petroleum oil

Also Published As

Publication number Publication date
IE46909B1 (en) 1983-11-02
AU516712B2 (en) 1981-06-18
SE437831B (sv) 1985-03-18
NO781880L (no) 1978-12-01
NL7805848A (nl) 1978-12-04
NO149065C (no) 1984-02-08
BG28712A3 (bg) 1980-06-16
SE7806287L (sv) 1978-12-01
DD135490A5 (de) 1979-05-09
FR2392991A1 (fr) 1978-12-29
DK239378A (da) 1978-12-01
FI63233C (fi) 1983-05-10
FI781690A7 (fi) 1978-12-01
HK19381A (en) 1981-05-15
ATA367778A (de) 1980-09-15
FR2392991B1 (en, 2012) 1982-10-22
HU180540B (en) 1983-03-28
ES470269A1 (es) 1979-01-01
BE867639A (fr) 1978-11-30
GB1581500A (en) 1980-12-17
CH637956A5 (de) 1983-08-31
SU797578A3 (ru) 1981-01-15
ZA783086B (en) 1980-02-27
DK148233C (da) 1985-10-21
CS202600B2 (en) 1981-01-30
PL207192A1 (pl) 1979-04-23
CA1081220A (en) 1980-07-08
IE781073L (en) 1978-11-30
AT361929B (de) 1981-04-10
NO149065B (no) 1983-10-31
GR64535B (en) 1980-04-10
PT68114A (de) 1978-06-01
JPS6216952B2 (en, 2012) 1987-04-15
FI63233B (fi) 1983-01-31
IL54815A (en) 1981-07-31
MY8100362A (en) 1981-12-31
AU3662478A (en) 1979-12-06
YU129478A (en) 1983-02-28
JPS543092A (en) 1979-01-11
DK148233B (da) 1985-05-13
NZ187428A (en) 1981-01-23
US4210648A (en) 1980-07-01

Similar Documents

Publication Publication Date Title
PL113999B1 (en) Process for preparing novel derivatives of 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones
EP0863141B1 (en) Substituted heteroaromatic derivatives
FI109537B (fi) Menetelmä imidatso[1,2-a]pyridiinien ja niiden suolojen valmistamiseksi
US4680296A (en) Piperidine derivatives and pharmaceutical compositions containing them
EP0705832B1 (en) Serotonergic modulators
JPH0739387B2 (ja) 新規１−ベンジル−アミノアルキル−ピロリジノン化合物及びその製造方法
US4916135A (en) N-heteroaryl-4-quinolinamines
JPH0873439A (ja) １−ベンジル−１，３−ジヒドロ−２ｈ−ベンズイミダゾール−２−オン誘導体、これらの調製およびこれらを含有する薬学的組成物
RU2284325C2 (ru) Производные фенил-3-аминометил-хинолона-2 в качестве ингибиторов no-синтетазы, способ их получения, биологически активные соединения и фармацевтическая композиция на их основе
DE69318920T2 (de) Ellipticinderivate mit Antitumorwirkung
CS207619B2 (en) Method of making the new derivatives of 5,11-dihydro-6h-pyrido 2,3-b 1,4 benzodiazepin-6-on
PL113628B1 (en) Process for preparing novel,substituted in position 11 5,11-dihydro-6h-pyrido/2,3-b//1,4/benzodiazepin-6-ones
SK103193A3 (en) Piperidine derivatives, process for their preparation and pharmaceutical compositions containing these derivatives
US4603130A (en) 1-substituted-2-(piperazinyl or homopiperazinyl)-benzimidazole compounds and pharmaceutical composition
NO164899B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolylindolforbindelser.
KR900004148B1 (ko) 피롤로[1,2-a][4,1]벤즈옥사제핀 유도체
US4163055A (en) 2,9-Dioxatricyclo[4,3,1,03,7 ] decane derivatives and pharmaceutical compositions thereof
US4228168A (en) Azepino [1,2,3-lm]-β-carboline compounds and pharmaceutical composition thereof
DE2724478A1 (de) Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4959375A (en) Piperidine derivatives useful as 5-HT3 antagonists
US8686147B2 (en) Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it
US5633255A (en) 1,2-dihydro-2-oxo-3-aminoquinoxaline derivatives, their preparation and their therapeutic application
KR810000809B1 (ko) 11-위치 치환 5,11-디하이드로-6H-피리도 [2,3-b][1,4] 벤조디아제핀-6-온의 제조공정
US4207331A (en) 2,9-Dioxatricyclo[4,3,1,03,7 ]decane derivatives and pharmaceutical compositions thereof
US4087530A (en) Substituted 6-phenyl-octahydrobenzo [c] [1,6] naphthyridines