PL108102B1 - Sposob wytwarzania nowych bis/3,5-dwukarbamoilo-2,method of producing new bis/3,5-dicarbamoylo-2,4,64,6-trojjodoanilidow/kwasu dwukarboksylowego -triiodoanilides of dicarboxylic acid - Google Patents

Sposob wytwarzania nowych bis/3,5-dwukarbamoilo-2,method of producing new bis/3,5-dicarbamoylo-2,4,64,6-trojjodoanilidow/kwasu dwukarboksylowego -triiodoanilides of dicarboxylic acid Download PDF

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Publication number
PL108102B1
PL108102B1 PL1977199019A PL19901977A PL108102B1 PL 108102 B1 PL108102 B1 PL 108102B1 PL 1977199019 A PL1977199019 A PL 1977199019A PL 19901977 A PL19901977 A PL 19901977A PL 108102 B1 PL108102 B1 PL 108102B1
Authority
PL
Poland
Prior art keywords
bis
acid
dicarboxylic acid
triiodoanilide
solution
Prior art date
Application number
PL1977199019A
Other languages
English (en)
Polish (pl)
Other versions
PL199019A1 (pl
Inventor
Heinrich Pfeiffer
Ulrich Speck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PL199019A1 publication Critical patent/PL199019A1/xx
Publication of PL108102B1 publication Critical patent/PL108102B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
PL1977199019A 1976-06-23 1977-06-20 Sposob wytwarzania nowych bis/3,5-dwukarbamoilo-2,method of producing new bis/3,5-dicarbamoylo-2,4,64,6-trojjodoanilidow/kwasu dwukarboksylowego -triiodoanilides of dicarboxylic acid PL108102B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2628517A DE2628517C2 (de) 1976-06-23 1976-06-23 Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel

Publications (2)

Publication Number Publication Date
PL199019A1 PL199019A1 (pl) 1978-03-28
PL108102B1 true PL108102B1 (pl) 1980-03-31

Family

ID=5981407

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1977199019A PL108102B1 (pl) 1976-06-23 1977-06-20 Sposob wytwarzania nowych bis/3,5-dwukarbamoilo-2,method of producing new bis/3,5-dicarbamoylo-2,4,64,6-trojjodoanilidow/kwasu dwukarboksylowego -triiodoanilides of dicarboxylic acid

Country Status (28)

Country Link
US (1) US4239747A (forum.php)
JP (2) JPS537637A (forum.php)
AT (1) AT361117B (forum.php)
AU (1) AU512304B2 (forum.php)
BE (1) BE856039A (forum.php)
CA (2) CA1106400A (forum.php)
CH (1) CH629751A5 (forum.php)
CS (1) CS199680B2 (forum.php)
DD (1) DD131014A5 (forum.php)
DE (1) DE2628517C2 (forum.php)
DK (2) DK150505C (forum.php)
ES (1) ES460007A1 (forum.php)
FI (1) FI67540C (forum.php)
FR (1) FR2355808A1 (forum.php)
GB (2) GB1588733A (forum.php)
GR (1) GR71696B (forum.php)
HU (1) HU174228B (forum.php)
IE (2) IE45225B1 (forum.php)
IL (2) IL52356A (forum.php)
IT (1) IT1237314B (forum.php)
LU (2) LU77588A1 (forum.php)
NL (1) NL189510C (forum.php)
NO (2) NO147447C (forum.php)
PL (1) PL108102B1 (forum.php)
PT (1) PT66690B (forum.php)
SE (1) SE436871B (forum.php)
SU (1) SU917696A3 (forum.php)
ZA (1) ZA773782B (forum.php)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH626873A5 (forum.php) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
DK273280A (da) * 1979-06-28 1980-12-29 Schering Ag Trijoderede 5-aminoisophthalsyrederivater
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
US4341756A (en) * 1980-01-31 1982-07-27 The Regents Of The University Of California Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media
JPS56127373A (en) * 1980-01-31 1981-10-06 Univ California Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent
DE3038853A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
NO161368C (no) * 1982-11-08 1989-08-09 Nyegaard & Co As Roentgenkontrastmidler samt radiologiske preparater derav.
FR2541272A1 (fr) * 1983-02-23 1984-08-24 Guerbet Sa Composes bromes et produits opacifiants en contenant
US4650903A (en) * 1984-06-21 1987-03-17 The Bf Goodrich Company Oligomeric amides as synergists for antioxidants and UV stabilizers
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
IT1252180B (it) * 1991-12-10 1995-06-05 Bracco Ind Chimica Spa 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
CN1038725C (zh) * 1993-12-04 1998-06-17 吉林省鹊源国际生物工程有限公司 复方天然香菇营养液
US6149891A (en) * 1995-05-31 2000-11-21 Israel Humanitarian Foundation Ltd. X-ray contrast medium and method for protecting against harmful effects thereof
IT1299202B1 (it) * 1998-05-08 2000-02-29 Dibra Spa Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
US7790141B2 (en) * 2003-08-11 2010-09-07 Pathak Holdings, Llc Radio-opaque compounds, compositions containing same and methods of their synthesis and use
JP5340281B2 (ja) 2007-07-12 2013-11-13 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
JP2011500531A (ja) 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
JP2011500533A (ja) 2007-10-12 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
ES2389975T3 (es) 2007-10-12 2012-11-05 Ge Healthcare As Agentes de contraste
EP2203189B1 (en) 2007-10-12 2012-07-18 GE Healthcare AS Contrast agents
JP2011500770A (ja) * 2007-10-30 2011-01-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
JP2011509943A (ja) * 2008-01-14 2011-03-31 マリンクロッド・インコーポレイテッド イオシメノールを調製するためのプロセス
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
JP6884698B2 (ja) 2014-11-21 2021-06-09 テクニカル ユニバーシティ オブ デンマークＴｅｃｈｎｉｃａｌ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｄｅｎｍａｒｋ 局所的薬物放出のためのゲル処方物
CA3023928A1 (en) 2016-05-20 2017-11-23 Technical University Of Denmark Palpable marker composition
US20220339285A1 (en) 2019-06-12 2022-10-27 Technical University Of Denmark Dissacharide formulations for controlled drug release

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2853424A (en) * 1952-08-06 1958-09-23 Schering Ag X-ray contrast agents comprising symmetrical bifunctional analogs of nu-acyl derivatives of 2, 4, 6 triiodo-3-amino benzoic acid
US3178473A (en) * 1962-03-02 1965-04-13 Nyegaard & Co As Process for the n-alkylation of acyl anilides halogen substituted in the nucleus
US3290366A (en) * 1963-03-06 1966-12-06 Mallinckrodt Chemical Works 5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives
GB1033776A (en) * 1963-06-06 1966-06-22 Sterling Drug Inc Iodinated acid amides and esters and salts thereof
US3732293A (en) * 1968-03-15 1973-05-08 Sterling Drug Inc Iodinated bis(aminobenzoic acids) and esters thereof
CH502104A (de) * 1968-05-02 1971-01-31 Bracco Ind Chimica Spa Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung
IL34803A (en) * 1969-06-27 1975-03-13 Nyegaard & Co As N-hydroxyalkyl substituted benzamides and iodo methanesulfonamide and radiological compositions containing them
US3660464A (en) * 1970-06-19 1972-05-02 Squibb & Sons Inc Tri-iodinated diaminobenzoic acid derivatives
BE787669A (fr) * 1971-08-17 1973-02-19 Schering Ag Anilides d'acide n-methyl-dicarboxylique triiodes, et leur procede de preparation
DD104193A5 (forum.php) * 1972-12-22 1974-03-05
DE2629228C2 (de) * 1976-06-25 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung
CH626873A5 (forum.php) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa

Also Published As

Publication number Publication date
PT66690B (de) 1978-11-17
NO148811B (no) 1983-09-12
FI771900A7 (forum.php) 1977-12-24
PT66690A (de) 1977-07-01
DD131014A5 (de) 1978-05-24
IE45226L (en) 1982-07-14
DK595284A (da) 1984-12-12
IE45226B1 (en) 1982-07-14
SU917696A3 (ru) 1982-03-30
NO148811C (no) 1983-12-21
GB1588733A (en) 1981-04-29
JPS6111220B2 (forum.php) 1986-04-01
ZA773782B (en) 1978-05-30
DK165973B (da) 1993-02-22
FR2355808A1 (fr) 1978-01-20
DK150505B (da) 1987-03-16
PL199019A1 (pl) 1978-03-28
DE2628517A1 (de) 1978-01-05
NL7705509A (nl) 1977-12-28
IL52356A (en) 1981-03-31
NL189510C (nl) 1993-05-03
CA1106401A (en) 1981-08-04
LU88292I2 (de) 1994-05-04
FI67540B (fi) 1984-12-31
SE436871B (sv) 1985-01-28
JPS61126059A (ja) 1986-06-13
IL52356A0 (en) 1977-08-31
FI67540C (fi) 1985-04-10
DE2628517C2 (de) 1985-02-21
CS199680B2 (en) 1980-07-31
NO772202L (no) 1977-12-27
JPS6232185B2 (forum.php) 1987-07-13
CH629751A5 (de) 1982-05-14
AU2632577A (en) 1979-01-04
JPS537637A (en) 1978-01-24
IL60344A0 (en) 1980-09-16
IE45225L (en) 1977-12-03
LU77588A1 (forum.php) 1977-09-29
ATA443777A (de) 1980-07-15
NO147447B (no) 1983-01-03
AT361117B (de) 1981-02-25
BE856039A (fr) 1977-12-23
IT1237314B (it) 1993-05-29
DK595284D0 (da) 1984-12-12
DK266177A (da) 1977-12-24
ES460007A1 (es) 1978-05-01
HU174228B (hu) 1979-11-28
US4239747A (en) 1980-12-16
CA1106400A (en) 1981-08-04
GB1588734A (en) 1981-04-29
NO147447C (no) 1983-04-13
GR71696B (forum.php) 1983-06-21
NO822674L (no) 1977-12-27
DK165973C (da) 1993-07-26
DK150505C (da) 1988-01-11
NL189510B (nl) 1992-12-01
IE45225B1 (en) 1982-07-14
SE7707230L (sv) 1977-12-24
FR2355808B1 (forum.php) 1979-03-09
AU512304B2 (en) 1980-10-02

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Effective date: 20080306

LAPS Decisions on the lapse of the protection rights

Effective date: 20041203