PH21386A - Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof - Google Patents

Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof

Info

Publication number
PH21386A
PH21386A PH26006A PH26006A PH21386A PH 21386 A PH21386 A PH 21386A PH 26006 A PH26006 A PH 26006A PH 26006 A PH26006 A PH 26006A PH 21386 A PH21386 A PH 21386A
Authority
PH
Philippines
Prior art keywords
platinum
preparation
pharmaceutical compositions
diamine complexes
diamine
Prior art date
Application number
PH26006A
Other languages
English (en)
Inventor
Berg Jan
Bulten Eric Jan
Verbeek Francois
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of PH21386A publication Critical patent/PH21386A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH26006A 1978-07-06 1981-08-04 Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof PH21386A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7807334A NL7807334A (nl) 1978-07-06 1978-07-06 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.

Publications (1)

Publication Number Publication Date
PH21386A true PH21386A (en) 1987-10-15

Family

ID=19831207

Family Applications (1)

Application Number Title Priority Date Filing Date
PH26006A PH21386A (en) 1978-07-06 1981-08-04 Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof

Country Status (36)

Country Link
US (1) US4410544A (nl)
JP (1) JPS5513280A (nl)
AR (1) AR226709A1 (nl)
AT (1) AT377251B (nl)
AU (1) AU533539B2 (nl)
BE (1) BE877527A (nl)
CA (1) CA1152088A (nl)
CH (2) CH649525A5 (nl)
CS (1) CS235301B2 (nl)
CY (1) CY1320A (nl)
DD (1) DD144780A5 (nl)
DE (1) DE2927056A1 (nl)
DK (1) DK153540C (nl)
ES (3) ES482240A1 (nl)
FI (1) FI76350C (nl)
FR (2) FR2430406A1 (nl)
GB (1) GB2024823B (nl)
GR (1) GR69248B (nl)
HK (1) HK9986A (nl)
HU (1) HU183014B (nl)
IE (1) IE48519B1 (nl)
IL (1) IL57717A (nl)
IT (1) IT1122011B (nl)
KE (1) KE3590A (nl)
LU (1) LU81470A1 (nl)
MY (1) MY8600400A (nl)
NL (1) NL7807334A (nl)
NO (1) NO163898C (nl)
NZ (1) NZ190923A (nl)
PH (1) PH21386A (nl)
PT (1) PT69877A (nl)
SE (1) SE7905927L (nl)
SG (1) SG91685G (nl)
SU (2) SU1160937A3 (nl)
YU (1) YU41652B (nl)
ZA (1) ZA793394B (nl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8204067A (nl) * 1982-10-21 1984-05-16 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
NZ197104A (en) * 1980-05-27 1984-05-31 Bristol Myers Co Soluble ammonium and sodium salts of 2-hydroxymalonato platinum ii derivatives
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS57156416A (en) * 1981-03-24 1982-09-27 Otsuka Chem Co Ltd Platinum (2) complex and antitumor agent comprising it as active ingredient
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
DE3305248A1 (de) * 1983-02-16 1984-08-16 Degussa Ag, 6000 Frankfurt Verfahren zur herstellung von reinem cis-platin-(ii)-diammin-dichlorid
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4720504A (en) * 1983-05-10 1988-01-19 Andrulis Research Corporation Use of bis-platinum complexes as antitumor agents
AU558747B2 (en) * 1983-05-10 1987-02-05 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
US4952676A (en) * 1984-06-27 1990-08-28 Johnson Matthey Plc Monoclonal antibody-platinum co-ordination compound complex
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4665210A (en) * 1984-12-17 1987-05-12 American Cyanamid Company Platinum complexes of aliphatic tricarboxylic acids
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
US4567285A (en) * 1985-07-10 1986-01-28 Yoshinori Kidani Complex compounds of platinum
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS6345290A (ja) * 1985-08-27 1988-02-26 Nippon Kayaku Co Ltd 新規白金錯体
US5116831A (en) * 1985-12-24 1992-05-26 Warner-Lambert Company Aminoalkyl-substituted cycloalkylamine platinum (II) complexes
US4970324A (en) * 1985-12-24 1990-11-13 Hoeschele James D Aminoalkyl-substituted azetidine platinum(II) complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4716157A (en) * 1986-03-20 1987-12-29 American Cyanamid Company Heterocyclic-1,2-diamine platinum complexes
JPH05345792A (ja) * 1986-07-01 1993-12-27 Nippon Kayaku Co Ltd 新規白金錯体
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
ATE86967T1 (de) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US4895960A (en) * 1989-01-23 1990-01-23 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
CH605550A5 (nl) * 1972-06-08 1978-09-29 Research Corp
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体

Also Published As

Publication number Publication date
US4410544A (en) 1983-10-18
AR226709A1 (es) 1982-08-13
FI76350B (fi) 1988-06-30
AU4867979A (en) 1980-02-07
ES490629A0 (es) 1980-12-01
HK9986A (en) 1986-02-14
IL57717A0 (en) 1979-11-30
HU183014B (en) 1984-04-28
IE48519B1 (en) 1985-02-20
DK153540B (da) 1988-07-25
IT1122011B (it) 1986-04-23
FR2430406B1 (nl) 1983-12-30
ES482240A1 (es) 1980-10-01
IT7924099A0 (it) 1979-07-04
FI792127A (fi) 1980-01-07
GR69248B (nl) 1982-05-11
ES490630A0 (es) 1980-12-01
ES8101080A1 (es) 1980-12-01
ES8101079A1 (es) 1980-12-01
DE2927056A1 (de) 1980-01-24
NO792240L (no) 1980-01-08
GB2024823B (en) 1982-12-08
SU1414850A1 (ru) 1988-08-07
SE7905927L (sv) 1980-01-07
AT377251B (de) 1985-02-25
CS235301B2 (en) 1985-05-15
AU533539B2 (en) 1983-12-01
YU41652B (en) 1987-12-31
DK284979A (da) 1980-01-07
CA1152088A (en) 1983-08-16
MY8600400A (en) 1986-12-31
CH649525A5 (de) 1985-05-31
YU166279A (en) 1983-01-21
PT69877A (en) 1979-08-01
FR2511685A1 (fr) 1983-02-25
BE877527A (nl) 1980-01-07
IE791271L (en) 1980-01-06
GB2024823A (en) 1980-01-16
CY1320A (en) 1986-06-27
NL7807334A (nl) 1980-01-08
ZA793394B (en) 1980-06-25
DD144780A5 (de) 1980-11-05
CH641758A5 (de) 1984-03-15
LU81470A1 (fr) 1980-02-14
JPS5513280A (en) 1980-01-30
SG91685G (en) 1986-07-25
DE2927056C2 (nl) 1990-08-30
NO163898B (no) 1990-04-30
FR2511685B1 (fr) 1985-10-18
ATA469079A (de) 1984-07-15
KE3590A (en) 1986-02-07
DK153540C (da) 1988-12-05
FR2430406A1 (fr) 1980-02-01
SU1160937A3 (ru) 1985-06-07
IL57717A (en) 1983-09-30
NO163898C (no) 1990-08-22
FI76350C (fi) 1988-10-10
NZ190923A (en) 1981-01-23
JPS648636B2 (nl) 1989-02-14

Similar Documents

Publication Publication Date Title
PH21386A (en) Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof
IL57020A (en) Carbazolyl-(4)-oxypropanolamine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
CY1250A (en) N-heterocyclyl-4-piperdinamines,methods for their preparation and pharmaceutical compositions comprising them
GR61176B (en) Pharmaceutical compositions and process for the preparation thereof
IL57672A (en) Phenethanolamines,their preparation and pharmaceutical compositions containing the same
ZA794472B (en) Pyridazinone-substituted benzimidazoles,processes for their preparation,and pharmaceutical compositions thereof
DE2960954D1 (en) 1-aryloxy-3-nitratoalkylamino-2-propanols, process for their preparation and pharmaceutical compositions
IL58238A (en) Aldehyde-treated allergen-containing substances,process for their preparation and pharmaceutical compositions comprising the same
DE2961552D1 (en) 1,2,3,5-tetrahydroimidazothienopyrimidin-2-ones, a process for their preparation and pharmaceutical compositions
DE2964209D1 (en) Spiro-furanohydantoin derivatives, process for their preparation and pharmaceutical compositions containing them
GB2019837A (en) N-Oxacyclic-alkylpiperidyl-diazacompounds, process for their manufacture and pharmaceutical compositions containing them
DE2966364D1 (en) Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them
ZA786054B (en) Novel 6-oxy-genated-3,20-dioxo-pregnane-derivatives,process for the preparation thereof,and pharmaceutical compositions containing them
ZA792042B (en) Substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them
IL56808A0 (en) 1-oxo-1h-pyrimido(6,1)benztheazole derivatives,process forthe preparation thereof and pharmaceutical compositions containing the same
GB2050833B (en) Pharmaceutical compositions and process for the preparation thereof
DE2964859D1 (en) Coumarin derivatives, process for preparing the same and pharmaceutical composition containing the same
ZA793682B (en) New piperidylbenzimidazolinone derivatives,processes for their preparation and pharmaceutical compositions containing them
IL60408A (en) Sulfur-containing isoquinoline derivatives,process for the preparation thereof and pharmaceutical compositions containing them
DE2961285D1 (en) Frenolicin b, process for preparation thereof and pharmaceutical compositions containing it
DE3060079D1 (en) Spiro-quinolylhydantoins, process for their preparation and pharmaceutical compositions thereof
IL62747A0 (en) 2-guanidinothiazole derivatives,process for the preparation thereof and pharmaceutical compositions comprising the same
IL53685A (en) N2-arylsulfonyl-l-argininamides and the pharmaceutical salts thereof,process for their preparation and pharmaceutical compositions containing them
DE2960503D1 (en) Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them
IL56531A (en) Purine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same