ES8101080A1 - Procedimiento de obtencion de un complejo de platino-amina - Google Patents

Procedimiento de obtencion de un complejo de platino-amina

Info

Publication number
ES8101080A1
ES8101080A1 ES490630A ES490630A ES8101080A1 ES 8101080 A1 ES8101080 A1 ES 8101080A1 ES 490630 A ES490630 A ES 490630A ES 490630 A ES490630 A ES 490630A ES 8101080 A1 ES8101080 A1 ES 8101080A1
Authority
ES
Spain
Prior art keywords
platinum
group
diamine
carbon atoms
mice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490630A
Other languages
English (en)
Other versions
ES490630A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Publication of ES490630A0 publication Critical patent/ES490630A0/es
Publication of ES8101080A1 publication Critical patent/ES8101080A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE UN COMPLEJO DE PLATINO-AMINA. CONSISTE EN: 1) HACER REACCIONAR UNA SOLUCION ACUOSA DE K2PTCL4 CON UNA SOLUCION ACUOSA SATURADA DE YODURO POTASICO. 2) ADICION DE UNA AMINA DE *FORMULA* FORMULA (I), RECUPERANDOSE EL COMPUESTO II. 3) SEPARACION DEL YODURO DE PLATA FORMADO Y REACCION CON UNA SOLUCION ACUOSA DE KX. TRATAMIENTO DEL CANCER, HINCHAZONES MALIGNOS Y TUMORES MALIGNOS.
ES490630A 1978-07-06 1980-04-16 Procedimiento de obtencion de un complejo de platino-amina Expired ES8101080A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7807334A NL7807334A (nl) 1978-07-06 1978-07-06 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.

Publications (2)

Publication Number Publication Date
ES490630A0 ES490630A0 (es) 1980-12-01
ES8101080A1 true ES8101080A1 (es) 1980-12-01

Family

ID=19831207

Family Applications (3)

Application Number Title Priority Date Filing Date
ES482240A Expired ES482240A1 (es) 1978-07-06 1979-07-05 Procedimiento de obtencion de un complejo de platinoamina.
ES490630A Expired ES8101080A1 (es) 1978-07-06 1980-04-16 Procedimiento de obtencion de un complejo de platino-amina
ES490629A Granted ES490629A0 (es) 1978-07-06 1980-04-16 Procedimiento de obtencion de un complejo de platino-amina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES482240A Expired ES482240A1 (es) 1978-07-06 1979-07-05 Procedimiento de obtencion de un complejo de platinoamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES490629A Granted ES490629A0 (es) 1978-07-06 1980-04-16 Procedimiento de obtencion de un complejo de platino-amina

Country Status (36)

Country Link
US (1) US4410544A (es)
JP (1) JPS5513280A (es)
AR (1) AR226709A1 (es)
AT (1) AT377251B (es)
AU (1) AU533539B2 (es)
BE (1) BE877527A (es)
CA (1) CA1152088A (es)
CH (2) CH649525A5 (es)
CS (1) CS235301B2 (es)
CY (1) CY1320A (es)
DD (1) DD144780A5 (es)
DE (1) DE2927056A1 (es)
DK (1) DK153540C (es)
ES (3) ES482240A1 (es)
FI (1) FI76350C (es)
FR (2) FR2430406A1 (es)
GB (1) GB2024823B (es)
GR (1) GR69248B (es)
HK (1) HK9986A (es)
HU (1) HU183014B (es)
IE (1) IE48519B1 (es)
IL (1) IL57717A (es)
IT (1) IT1122011B (es)
KE (1) KE3590A (es)
LU (1) LU81470A1 (es)
MY (1) MY8600400A (es)
NL (1) NL7807334A (es)
NO (1) NO163898C (es)
NZ (1) NZ190923A (es)
PH (1) PH21386A (es)
PT (1) PT69877A (es)
SE (1) SE7905927L (es)
SG (1) SG91685G (es)
SU (2) SU1160937A3 (es)
YU (1) YU41652B (es)
ZA (1) ZA793394B (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8204067A (nl) * 1982-10-21 1984-05-16 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
NZ197104A (en) * 1980-05-27 1984-05-31 Bristol Myers Co Soluble ammonium and sodium salts of 2-hydroxymalonato platinum ii derivatives
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS57156416A (en) * 1981-03-24 1982-09-27 Otsuka Chem Co Ltd Platinum (2) complex and antitumor agent comprising it as active ingredient
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
DE3305248A1 (de) * 1983-02-16 1984-08-16 Degussa Ag, 6000 Frankfurt Verfahren zur herstellung von reinem cis-platin-(ii)-diammin-dichlorid
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
EP0137900B1 (en) * 1983-05-10 1990-05-09 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4720504A (en) * 1983-05-10 1988-01-19 Andrulis Research Corporation Use of bis-platinum complexes as antitumor agents
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
US4952676A (en) * 1984-06-27 1990-08-28 Johnson Matthey Plc Monoclonal antibody-platinum co-ordination compound complex
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4665210A (en) * 1984-12-17 1987-05-12 American Cyanamid Company Platinum complexes of aliphatic tricarboxylic acids
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
US4567285A (en) * 1985-07-10 1986-01-28 Yoshinori Kidani Complex compounds of platinum
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS6345290A (ja) * 1985-08-27 1988-02-26 Nippon Kayaku Co Ltd 新規白金錯体
US4970324A (en) * 1985-12-24 1990-11-13 Hoeschele James D Aminoalkyl-substituted azetidine platinum(II) complexes
US5116831A (en) * 1985-12-24 1992-05-26 Warner-Lambert Company Aminoalkyl-substituted cycloalkylamine platinum (II) complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4716157A (en) * 1986-03-20 1987-12-29 American Cyanamid Company Heterocyclic-1,2-diamine platinum complexes
JPH05345792A (ja) * 1986-07-01 1993-12-27 Nippon Kayaku Co Ltd 新規白金錯体
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
DE3843571A1 (de) * 1988-01-09 1989-07-20 Asta Pharma Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US4895960A (en) * 1989-01-23 1990-01-23 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
CH588505A5 (es) * 1972-06-08 1977-06-15 Research Corp
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体

Also Published As

Publication number Publication date
FR2511685A1 (fr) 1983-02-25
FI792127A (fi) 1980-01-07
YU166279A (en) 1983-01-21
ES8101079A1 (es) 1980-12-01
AR226709A1 (es) 1982-08-13
DD144780A5 (de) 1980-11-05
FR2511685B1 (fr) 1985-10-18
MY8600400A (en) 1986-12-31
NZ190923A (en) 1981-01-23
GB2024823B (en) 1982-12-08
PH21386A (en) 1987-10-15
AU533539B2 (en) 1983-12-01
FI76350B (fi) 1988-06-30
IL57717A (en) 1983-09-30
SU1414850A1 (ru) 1988-08-07
JPS648636B2 (es) 1989-02-14
SU1160937A3 (ru) 1985-06-07
PT69877A (en) 1979-08-01
CY1320A (en) 1986-06-27
SG91685G (en) 1986-07-25
ATA469079A (de) 1984-07-15
DE2927056A1 (de) 1980-01-24
IT7924099A0 (it) 1979-07-04
LU81470A1 (fr) 1980-02-14
FR2430406B1 (es) 1983-12-30
YU41652B (en) 1987-12-31
AU4867979A (en) 1980-02-07
CS235301B2 (en) 1985-05-15
US4410544A (en) 1983-10-18
KE3590A (en) 1986-02-07
ES482240A1 (es) 1980-10-01
CA1152088A (en) 1983-08-16
IL57717A0 (en) 1979-11-30
CH641758A5 (de) 1984-03-15
NL7807334A (nl) 1980-01-08
ZA793394B (en) 1980-06-25
SE7905927L (sv) 1980-01-07
HU183014B (en) 1984-04-28
NO792240L (no) 1980-01-08
IT1122011B (it) 1986-04-23
JPS5513280A (en) 1980-01-30
CH649525A5 (de) 1985-05-31
IE791271L (en) 1980-01-06
DK284979A (da) 1980-01-07
DK153540C (da) 1988-12-05
FR2430406A1 (fr) 1980-02-01
GB2024823A (en) 1980-01-16
BE877527A (nl) 1980-01-07
IE48519B1 (en) 1985-02-20
NO163898C (no) 1990-08-22
ES490630A0 (es) 1980-12-01
HK9986A (en) 1986-02-14
ES490629A0 (es) 1980-12-01
GR69248B (es) 1982-05-11
NO163898B (no) 1990-04-30
DE2927056C2 (es) 1990-08-30
AT377251B (de) 1985-02-25
FI76350C (fi) 1988-10-10
DK153540B (da) 1988-07-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303