ZA793394B - Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed - Google Patents

Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed

Info

Publication number
ZA793394B
ZA793394B ZA793394A ZA793394A ZA793394B ZA 793394 B ZA793394 B ZA 793394B ZA 793394 A ZA793394 A ZA 793394A ZA 793394 A ZA793394 A ZA 793394A ZA 793394 B ZA793394 B ZA 793394B
Authority
ZA
South Africa
Prior art keywords
platinum
medicine
preparation
diamine
cancer
Prior art date
Application number
ZA793394A
Other languages
English (en)
Inventor
F Verbeek
J Berg
E Bulten
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Publication of ZA793394B publication Critical patent/ZA793394B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA793394A 1978-07-06 1979-07-06 Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed ZA793394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7807334A NL7807334A (nl) 1978-07-06 1978-07-06 Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.

Publications (1)

Publication Number Publication Date
ZA793394B true ZA793394B (en) 1980-06-25

Family

ID=19831207

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA793394A ZA793394B (en) 1978-07-06 1979-07-06 Platinum-diamine complexes,a method for the preparation thereof,a method for the preparation of a medicine using such a platinum-diamine complex for the treatment of cancer,as well as a medicine thus formed

Country Status (36)

Country Link
US (1) US4410544A (xx)
JP (1) JPS5513280A (xx)
AR (1) AR226709A1 (xx)
AT (1) AT377251B (xx)
AU (1) AU533539B2 (xx)
BE (1) BE877527A (xx)
CA (1) CA1152088A (xx)
CH (2) CH641758A5 (xx)
CS (1) CS235301B2 (xx)
CY (1) CY1320A (xx)
DD (1) DD144780A5 (xx)
DE (1) DE2927056A1 (xx)
DK (1) DK153540C (xx)
ES (3) ES482240A1 (xx)
FI (1) FI76350C (xx)
FR (2) FR2430406A1 (xx)
GB (1) GB2024823B (xx)
GR (1) GR69248B (xx)
HK (1) HK9986A (xx)
HU (1) HU183014B (xx)
IE (1) IE48519B1 (xx)
IL (1) IL57717A (xx)
IT (1) IT1122011B (xx)
KE (1) KE3590A (xx)
LU (1) LU81470A1 (xx)
MY (1) MY8600400A (xx)
NL (1) NL7807334A (xx)
NO (1) NO163898C (xx)
NZ (1) NZ190923A (xx)
PH (1) PH21386A (xx)
PT (1) PT69877A (xx)
SE (1) SE7905927L (xx)
SG (1) SG91685G (xx)
SU (2) SU1160937A3 (xx)
YU (1) YU41652B (xx)
ZA (1) ZA793394B (xx)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8204067A (nl) * 1982-10-21 1984-05-16 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
AU538863B2 (en) * 1980-05-27 1984-08-30 Bristol-Myers Company Platinum complex salts have anti-tumor property
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS57156416A (en) * 1981-03-24 1982-09-27 Otsuka Chem Co Ltd Platinum (2) complex and antitumor agent comprising it as active ingredient
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
DE3305248A1 (de) * 1983-02-16 1984-08-16 Degussa Ag, 6000 Frankfurt Verfahren zur herstellung von reinem cis-platin-(ii)-diammin-dichlorid
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
ZA843515B (en) * 1983-05-10 1985-01-30 Andrulis Res Corp Bis-platinum complexes as antitumor agents
US4720504A (en) * 1983-05-10 1988-01-19 Andrulis Research Corporation Use of bis-platinum complexes as antitumor agents
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
US4952676A (en) * 1984-06-27 1990-08-28 Johnson Matthey Plc Monoclonal antibody-platinum co-ordination compound complex
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4665210A (en) * 1984-12-17 1987-05-12 American Cyanamid Company Platinum complexes of aliphatic tricarboxylic acids
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
US4567285A (en) * 1985-07-10 1986-01-28 Yoshinori Kidani Complex compounds of platinum
JPS6345290A (ja) * 1985-08-27 1988-02-26 Nippon Kayaku Co Ltd 新規白金錯体
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US5116831A (en) * 1985-12-24 1992-05-26 Warner-Lambert Company Aminoalkyl-substituted cycloalkylamine platinum (II) complexes
US4970324A (en) * 1985-12-24 1990-11-13 Hoeschele James D Aminoalkyl-substituted azetidine platinum(II) complexes
US4880790A (en) * 1986-01-31 1989-11-14 American Cyanamid Company (Gem-heterocyclodimethanamine-N,N')platinum complexes
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4716157A (en) * 1986-03-20 1987-12-29 American Cyanamid Company Heterocyclic-1,2-diamine platinum complexes
JPH05345792A (ja) * 1986-07-01 1993-12-27 Nippon Kayaku Co Ltd 新規白金錯体
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
AT390065B (de) * 1987-10-08 1990-03-12 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
EP0324154B1 (de) * 1988-01-09 1993-03-17 ASTA Medica Aktiengesellschaft 1,2-Bis(aminomethyl)cyclobutan-Platin-Komplexe
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US4895960A (en) * 1989-01-23 1990-01-23 University Of Cincinnati Cyclo substituted propyleneamine oxime and its use as a brain imaging agent
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
CH588505A5 (xx) * 1972-06-08 1977-06-15 Research Corp
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体

Also Published As

Publication number Publication date
HU183014B (en) 1984-04-28
DD144780A5 (de) 1980-11-05
US4410544A (en) 1983-10-18
SU1414850A1 (ru) 1988-08-07
CY1320A (en) 1986-06-27
NZ190923A (en) 1981-01-23
DK153540C (da) 1988-12-05
FR2430406A1 (fr) 1980-02-01
ES8101079A1 (es) 1980-12-01
DK284979A (da) 1980-01-07
FR2511685A1 (fr) 1983-02-25
GR69248B (xx) 1982-05-11
FR2511685B1 (fr) 1985-10-18
CA1152088A (en) 1983-08-16
PT69877A (en) 1979-08-01
ES490630A0 (es) 1980-12-01
SU1160937A3 (ru) 1985-06-07
CH641758A5 (de) 1984-03-15
IE48519B1 (en) 1985-02-20
DE2927056A1 (de) 1980-01-24
NO163898B (no) 1990-04-30
ES482240A1 (es) 1980-10-01
ES8101080A1 (es) 1980-12-01
CH649525A5 (de) 1985-05-31
SG91685G (en) 1986-07-25
FR2430406B1 (xx) 1983-12-30
NL7807334A (nl) 1980-01-08
IT1122011B (it) 1986-04-23
HK9986A (en) 1986-02-14
AR226709A1 (es) 1982-08-13
KE3590A (en) 1986-02-07
GB2024823B (en) 1982-12-08
BE877527A (nl) 1980-01-07
AT377251B (de) 1985-02-25
FI792127A (fi) 1980-01-07
DK153540B (da) 1988-07-25
NO163898C (no) 1990-08-22
SE7905927L (sv) 1980-01-07
JPS5513280A (en) 1980-01-30
CS235301B2 (en) 1985-05-15
NO792240L (no) 1980-01-08
AU4867979A (en) 1980-02-07
JPS648636B2 (xx) 1989-02-14
PH21386A (en) 1987-10-15
IT7924099A0 (it) 1979-07-04
IL57717A0 (en) 1979-11-30
ATA469079A (de) 1984-07-15
YU166279A (en) 1983-01-21
FI76350B (fi) 1988-06-30
IL57717A (en) 1983-09-30
YU41652B (en) 1987-12-31
LU81470A1 (fr) 1980-02-14
AU533539B2 (en) 1983-12-01
DE2927056C2 (xx) 1990-08-30
GB2024823A (en) 1980-01-16
ES490629A0 (es) 1980-12-01
IE791271L (en) 1980-01-06
MY8600400A (en) 1986-12-31
FI76350C (fi) 1988-10-10

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