ES2000614A6 - Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'" - Google Patents
Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'"Info
- Publication number
- ES2000614A6 ES2000614A6 ES8601525A ES8601525A ES2000614A6 ES 2000614 A6 ES2000614 A6 ES 2000614A6 ES 8601525 A ES8601525 A ES 8601525A ES 8601525 A ES8601525 A ES 8601525A ES 2000614 A6 ES2000614 A6 ES 2000614A6
- Authority
- ES
- Spain
- Prior art keywords
- butene
- complexes
- platinum
- preparing
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- HRGDZIGMBDGFTC-UHFFFAOYSA-N platinum(2+) Chemical compound [Pt+2] HRGDZIGMBDGFTC-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
CONSISTE EN LA REACCION DE LOS COMPUESTOS DE FORMULA GENERAL (II) CON UN COMPUESTO DE FORMULA GENERAL (III), OBTENIENDOSE ASI LOS NUEVOS COMPLEJOS DE PLATINO (II) DERIVADOS DEL 2,3-DIMERCAPTO-2-BUTENE-DINITRILATO (2-)-S,SK DE FORMULA GENERAL (I), DONDE R ES UN GRUPO DIALQUILSULFURO O TRIALQUILFOSFINA, DE MANERA QUE EL NUMERO DE CARBONOS DE CADA RADICAL ALQUILO ES DOS COMO MAXIMO, PUDIENDO CONTENER LOS RADICALES ALQUILO UN GRUPO HIDROXILO O NO. DE APLICACION FARMACOLOGICA POR SU EFECTO ANTITUMORAL.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8601525A ES2000614A6 (es) | 1986-08-04 | 1986-08-04 | Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'" |
| ZA875344A ZA875344B (en) | 1986-08-04 | 1987-07-21 | Platinum(ii)complexes of 2,3-dimercapto-2-butene-dinitrilate(2-)-s,s'process for their production and pharmaceutical compositions containing them |
| CA000543164A CA1296735C (en) | 1986-08-04 | 1987-07-28 | Platinum(ii) complexes of 2,3-dimercapto-2-butene- dinitrilate(2-)-s,s' derivatives and process for their production |
| PH35616A PH23809A (en) | 1986-08-04 | 1987-08-03 | Platinum(ii)complexes of 2,3-dimercapto-2-butene-dinitrilate(2)-s,s'-derivatives and the method for preparing the same |
| JP62192763A JPS6341489A (ja) | 1986-08-04 | 1987-08-03 | 2,3−ジメルカプト−2−ブテン−ジニトリレ−ト(2−)−s,s′誘導体の白金(2)錯体 |
| DE8787111190T DE3774373D1 (de) | 1986-08-04 | 1987-08-03 | Komplexe von platin-(ii) von 2,3 dinitrilo-2-buten-2,3-dithiolat, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
| EP87111190A EP0258655B1 (en) | 1986-08-04 | 1987-08-03 | Complexes of platinum (ii) 2,3-dinitrilo-2-butene-2,3-dithiolate, a process for preparing them and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES8601525A ES2000614A6 (es) | 1986-08-04 | 1986-08-04 | Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'" |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000614A6 true ES2000614A6 (es) | 1988-03-01 |
Family
ID=8248116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8601525A Expired ES2000614A6 (es) | 1986-08-04 | 1986-08-04 | Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'" |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0258655B1 (es) |
| JP (1) | JPS6341489A (es) |
| CA (1) | CA1296735C (es) |
| DE (1) | DE3774373D1 (es) |
| ES (1) | ES2000614A6 (es) |
| PH (1) | PH23809A (es) |
| ZA (1) | ZA875344B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR940010295B1 (ko) * | 1991-07-05 | 1994-10-22 | 한국과학기술연구원 | 신규 항암성 백금 착화합물 유도체 및 그 제조방법 |
| JP3849005B2 (ja) * | 2000-03-08 | 2006-11-22 | 独立行政法人産業技術総合研究所 | 増感剤として有用な白金錯体 |
| EP1394169B1 (en) * | 2002-08-29 | 2007-04-18 | Jih-Ru Hwu | Organometallic complex |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1274529A (en) * | 1985-09-05 | 1990-09-25 | Federico Sampedro | Platinum(ii) complexes of 1,1-cyclobutane- dicarboxylate and process for their production |
-
1986
- 1986-08-04 ES ES8601525A patent/ES2000614A6/es not_active Expired
-
1987
- 1987-07-21 ZA ZA875344A patent/ZA875344B/xx unknown
- 1987-07-28 CA CA000543164A patent/CA1296735C/en not_active Expired - Fee Related
- 1987-08-03 PH PH35616A patent/PH23809A/en unknown
- 1987-08-03 EP EP87111190A patent/EP0258655B1/en not_active Expired - Lifetime
- 1987-08-03 JP JP62192763A patent/JPS6341489A/ja active Pending
- 1987-08-03 DE DE8787111190T patent/DE3774373D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6341489A (ja) | 1988-02-22 |
| ZA875344B (en) | 1988-01-27 |
| EP0258655A2 (en) | 1988-03-09 |
| PH23809A (en) | 1989-11-23 |
| CA1296735C (en) | 1992-03-03 |
| EP0258655A3 (en) | 1989-05-24 |
| DE3774373D1 (de) | 1991-12-12 |
| EP0258655B1 (en) | 1991-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-08-04 |
|
| FD1A | Patent lapsed |
Effective date: 20000601 |