PH18490A - Bis-hydroxymethyl carbonate bridged antibacterial agents - Google Patents

Bis-hydroxymethyl carbonate bridged antibacterial agents

Info

Publication number
PH18490A
PH18490A PH28301A PH28301A PH18490A PH 18490 A PH18490 A PH 18490A PH 28301 A PH28301 A PH 28301A PH 28301 A PH28301 A PH 28301A PH 18490 A PH18490 A PH 18490A
Authority
PH
Philippines
Prior art keywords
bis
antibacterial agents
bridged
hydroxymethyl
certain
Prior art date
Application number
PH28301A
Other languages
English (en)
Inventor
Ernest Seiichi Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH18490A publication Critical patent/PH18490A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/06Preparation of esters of carbonic or haloformic acids from organic carbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PH28301A 1981-12-22 1982-12-20 Bis-hydroxymethyl carbonate bridged antibacterial agents PH18490A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/334,017 US4359472A (en) 1981-12-22 1981-12-22 Bis-hydroxymethyl carbonate bridged antibacterial agents
AU23672/84A AU560708B2 (en) 1981-12-22 1984-01-20 Penicillin intermediates

Publications (1)

Publication Number Publication Date
PH18490A true PH18490A (en) 1985-08-02

Family

ID=25619060

Family Applications (1)

Application Number Title Priority Date Filing Date
PH28301A PH18490A (en) 1981-12-22 1982-12-20 Bis-hydroxymethyl carbonate bridged antibacterial agents

Country Status (25)

Country Link
US (1) US4359472A (no)
EP (1) EP0082666B1 (no)
JP (1) JPS58116490A (no)
KR (1) KR860001362B1 (no)
AT (1) ATE17853T1 (no)
AU (2) AU535634B2 (no)
CS (1) CS236779B2 (no)
DD (3) DD222315A5 (no)
DE (1) DE3269029D1 (no)
DK (1) DK565582A (no)
EG (1) EG15866A (no)
ES (3) ES518490A0 (no)
FI (1) FI75570C (no)
GR (1) GR77097B (no)
HU (1) HU188825B (no)
IE (1) IE54334B1 (no)
IL (1) IL67523A (no)
NO (2) NO160300C (no)
NZ (1) NZ202855A (no)
PH (1) PH18490A (no)
PL (2) PL140731B1 (no)
PT (1) PT76011B (no)
SU (2) SU1217261A3 (no)
YU (1) YU42823B (no)
ZA (1) ZA829375B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents
US4434173A (en) * 1982-08-23 1984-02-28 Pfizer Inc. Bis-esters of 4,5-di(hydroxymethyl)-2-oxo-1,3-dioxole as antibacterial agents
US4448732A (en) * 1982-09-07 1984-05-15 Pfizer Inc. 2-Oxo-1,3-dioxol-4-ylmethyl esters of penicillanic acid 1,1-dioxide
US4530792A (en) * 1982-11-01 1985-07-23 Pfizer Inc. Process and intermediates for preparation of 1,1-dioxopenicillanoyloxymethyl 6-beta-aminopenicillanate
CN112724162B (zh) * 2020-12-28 2022-06-10 华南农业大学 一种阿莫西林-舒巴坦杂合分子的合成方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985648A (en) * 1958-10-06 1961-05-23 Doyle Frank Peter Alpha-aminobenzylpenicillins
DE1249280B (de) * 1962-11-02 1967-09-07 Beecham GrouD Limited, Brentford Middlesex (Großbritannien) Verfahren zur Herstellung von Hydroxybenzyl y amino-pemciUmen
US3520876A (en) * 1967-11-01 1970-07-21 American Home Prod Process for the preparation of 6-(alpha-aminoacylamino)penicillanic acids
BE784800A (fr) * 1971-06-15 1972-10-02 Yamanouchi Pharma Co Ltd Procede de preparation de nouveaux derives esters oxymethyliques de la penicilline et de la cephalosporine
GB1425827A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephalosporins
ES436565A1 (es) * 1974-06-05 1977-04-01 Bristol Myers Co Un procedimiento para la preparacion de acidos acetamidope- nicilanicos.
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IE49880B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
BE881675A (fr) * 1979-02-13 1980-08-12 Leo Pharm Prod Ltd B-lactames derives de l'acide penicillanique leur preparation et leurs utilisations therapeutiques
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents

Also Published As

Publication number Publication date
DD216024A5 (de) 1984-11-28
FI824408A0 (fi) 1982-12-21
FI824408L (fi) 1983-06-23
FI75570C (fi) 1988-07-11
AU535634B2 (en) 1984-03-29
AU2367284A (en) 1984-05-10
GR77097B (no) 1984-09-06
PT76011A (en) 1983-01-01
PL140731B1 (en) 1987-05-30
PL239590A1 (en) 1985-01-16
NZ202855A (en) 1985-09-13
JPH0119394B2 (no) 1989-04-11
KR860001362B1 (ko) 1986-09-16
ATE17853T1 (de) 1986-02-15
CS236779B2 (en) 1985-05-15
DK565582A (da) 1983-06-23
IL67523A0 (en) 1983-05-15
DE3269029D1 (en) 1986-03-20
IE54334B1 (en) 1989-08-30
PL248638A1 (en) 1985-05-07
NO824304L (no) 1983-06-23
IE823035L (en) 1983-06-22
ES8502119A1 (es) 1984-12-16
NO160300C (no) 1989-04-05
AU9172282A (en) 1983-08-04
ES524778A0 (es) 1984-12-16
ES524779A0 (es) 1985-01-01
FI75570B (fi) 1988-03-31
YU280082A (en) 1985-04-30
JPS58116490A (ja) 1983-07-11
ZA829375B (en) 1983-10-26
EG15866A (en) 1986-09-30
ES8402157A1 (es) 1984-02-01
PT76011B (en) 1985-12-13
ES8502443A1 (es) 1985-01-01
YU42823B (en) 1988-12-31
NO160300B (no) 1988-12-27
SU1169541A3 (ru) 1985-07-23
HU188825B (en) 1986-05-28
EP0082666A1 (en) 1983-06-29
EP0082666B1 (en) 1986-02-05
DD208621A5 (de) 1984-04-04
US4359472A (en) 1982-11-16
ES518490A0 (es) 1984-02-01
AU560708B2 (en) 1987-04-16
PL140375B1 (en) 1987-04-30
DD222315A5 (de) 1985-05-15
IL67523A (en) 1986-04-29
SU1217261A3 (ru) 1986-03-07
NO832871L (no) 1983-06-23

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