ATE17853T1 - Bis-hydroxymethyl carbonat-derivate als antibakterielle mittel. - Google Patents

Bis-hydroxymethyl carbonat-derivate als antibakterielle mittel.

Info

Publication number
ATE17853T1
ATE17853T1 AT82306684T AT82306684T ATE17853T1 AT E17853 T1 ATE17853 T1 AT E17853T1 AT 82306684 T AT82306684 T AT 82306684T AT 82306684 T AT82306684 T AT 82306684T AT E17853 T1 ATE17853 T1 AT E17853T1
Authority
AT
Austria
Prior art keywords
bis
antibacterial agents
carbonate derivatives
hydroxymethyl
certain
Prior art date
Application number
AT82306684T
Other languages
English (en)
Inventor
Ernest Seiichi Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE17853T1 publication Critical patent/ATE17853T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/06—Preparation of esters of carbonic or haloformic acids from organic carbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
AT82306684T 1981-12-22 1982-12-14 Bis-hydroxymethyl carbonat-derivate als antibakterielle mittel. ATE17853T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/334,017 US4359472A (en) 1981-12-22 1981-12-22 Bis-hydroxymethyl carbonate bridged antibacterial agents
AU23672/84A AU560708B2 (en) 1981-12-22 1984-01-20 Penicillin intermediates

Publications (1)

Publication Number Publication Date
ATE17853T1 true ATE17853T1 (de) 1986-02-15

Family

ID=25619060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82306684T ATE17853T1 (de) 1981-12-22 1982-12-14 Bis-hydroxymethyl carbonat-derivate als antibakterielle mittel.

Country Status (25)

Country Link
US (1) US4359472A (de)
EP (1) EP0082666B1 (de)
JP (1) JPS58116490A (de)
KR (1) KR860001362B1 (de)
AT (1) ATE17853T1 (de)
AU (2) AU535634B2 (de)
CS (1) CS236779B2 (de)
DD (3) DD222315A5 (de)
DE (1) DE3269029D1 (de)
DK (1) DK565582A (de)
EG (1) EG15866A (de)
ES (3) ES518490A0 (de)
FI (1) FI75570C (de)
GR (1) GR77097B (de)
HU (1) HU188825B (de)
IE (1) IE54334B1 (de)
IL (1) IL67523A (de)
NO (2) NO160300C (de)
NZ (1) NZ202855A (de)
PH (1) PH18490A (de)
PL (2) PL140375B1 (de)
PT (1) PT76011B (de)
SU (2) SU1217261A3 (de)
YU (1) YU42823B (de)
ZA (1) ZA829375B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents
US4434173A (en) * 1982-08-23 1984-02-28 Pfizer Inc. Bis-esters of 4,5-di(hydroxymethyl)-2-oxo-1,3-dioxole as antibacterial agents
US4448732A (en) * 1982-09-07 1984-05-15 Pfizer Inc. 2-Oxo-1,3-dioxol-4-ylmethyl esters of penicillanic acid 1,1-dioxide
US4530792A (en) * 1982-11-01 1985-07-23 Pfizer Inc. Process and intermediates for preparation of 1,1-dioxopenicillanoyloxymethyl 6-beta-aminopenicillanate
CN112724162B (zh) * 2020-12-28 2022-06-10 华南农业大学 一种阿莫西林-舒巴坦杂合分子的合成方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985648A (en) * 1958-10-06 1961-05-23 Doyle Frank Peter Alpha-aminobenzylpenicillins
NL299897A (de) * 1962-11-02
US3520876A (en) * 1967-11-01 1970-07-21 American Home Prod Process for the preparation of 6-(alpha-aminoacylamino)penicillanic acids
BE784800A (fr) * 1971-06-15 1972-10-02 Yamanouchi Pharma Co Ltd Procede de preparation de nouveaux derives esters oxymethyliques de la penicilline et de la cephalosporine
GB1425827A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephalosporins
ES436565A1 (es) * 1974-06-05 1977-04-01 Bristol Myers Co Un procedimiento para la preparacion de acidos acetamidope- nicilanicos.
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IE49880B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
ZA80796B (en) * 1979-02-13 1981-02-25 Leo Pharm Prod Ltd Chemical compounds
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents

Also Published As

Publication number Publication date
NO824304L (no) 1983-06-23
YU280082A (en) 1985-04-30
ES524778A0 (es) 1984-12-16
IE823035L (en) 1983-06-22
AU560708B2 (en) 1987-04-16
DD222315A5 (de) 1985-05-15
DD208621A5 (de) 1984-04-04
IE54334B1 (en) 1989-08-30
NO160300B (no) 1988-12-27
AU2367284A (en) 1984-05-10
SU1217261A3 (ru) 1986-03-07
IL67523A0 (en) 1983-05-15
EP0082666B1 (de) 1986-02-05
NO160300C (no) 1989-04-05
US4359472A (en) 1982-11-16
EG15866A (en) 1986-09-30
DE3269029D1 (en) 1986-03-20
HU188825B (en) 1986-05-28
DK565582A (da) 1983-06-23
IL67523A (en) 1986-04-29
ES8502119A1 (es) 1984-12-16
AU535634B2 (en) 1984-03-29
PL140731B1 (en) 1987-05-30
ES8402157A1 (es) 1984-02-01
PT76011A (en) 1983-01-01
PL140375B1 (en) 1987-04-30
ES524779A0 (es) 1985-01-01
GR77097B (de) 1984-09-06
PT76011B (en) 1985-12-13
PH18490A (en) 1985-08-02
JPH0119394B2 (de) 1989-04-11
JPS58116490A (ja) 1983-07-11
FI75570B (fi) 1988-03-31
YU42823B (en) 1988-12-31
SU1169541A3 (ru) 1985-07-23
FI824408A0 (fi) 1982-12-21
ZA829375B (en) 1983-10-26
AU9172282A (en) 1983-08-04
KR860001362B1 (ko) 1986-09-16
NO832871L (no) 1983-06-23
PL239590A1 (en) 1985-01-16
ES8502443A1 (es) 1985-01-01
CS236779B2 (en) 1985-05-15
FI824408L (fi) 1983-06-23
ES518490A0 (es) 1984-02-01
DD216024A5 (de) 1984-11-28
FI75570C (fi) 1988-07-11
NZ202855A (en) 1985-09-13
EP0082666A1 (de) 1983-06-29
PL248638A1 (en) 1985-05-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee