PH12015501310B1 - NUTRIENT ENRICHED MEDIA FOR hUTC GROWTH - Google Patents

NUTRIENT ENRICHED MEDIA FOR hUTC GROWTH Download PDF

Info

Publication number
PH12015501310B1
PH12015501310B1 PH12015501310A PH12015501310A PH12015501310B1 PH 12015501310 B1 PH12015501310 B1 PH 12015501310B1 PH 12015501310 A PH12015501310 A PH 12015501310A PH 12015501310 A PH12015501310 A PH 12015501310A PH 12015501310 B1 PH12015501310 B1 PH 12015501310B1
Authority
PH
Philippines
Prior art keywords
cells
cell
microcarriers
medium
culture
Prior art date
Application number
PH12015501310A
Other languages
English (en)
Other versions
PH12015501310A1 (en
Inventor
Ravinder Bhatia
L S Klaudyne Hong
Sadettin S Ozturk
Venkat H Kamaraju
Original Assignee
Depuy Synthes Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Synthes Products Inc filed Critical Depuy Synthes Products Inc
Publication of PH12015501310A1 publication Critical patent/PH12015501310A1/en
Publication of PH12015501310B1 publication Critical patent/PH12015501310B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0037Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • C12N5/0075General culture methods using substrates using microcarriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • C12N2500/33Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PH12015501310A 2012-12-14 2015-06-09 NUTRIENT ENRICHED MEDIA FOR hUTC GROWTH PH12015501310B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/715,532 US20140170748A1 (en) 2012-12-14 2012-12-14 Nutrient Enriched Media for hUTC Growth
PCT/US2013/074615 WO2014093598A1 (en) 2012-12-14 2013-12-12 NUTRIENT ENRICHED MEDIA FOR hUTC GROWTH

Publications (2)

Publication Number Publication Date
PH12015501310A1 PH12015501310A1 (en) 2015-09-02
PH12015501310B1 true PH12015501310B1 (en) 2015-09-02

Family

ID=49881127

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12015501310A PH12015501310B1 (en) 2012-12-14 2015-06-09 NUTRIENT ENRICHED MEDIA FOR hUTC GROWTH

Country Status (17)

Country Link
US (1) US20140170748A1 (enExample)
EP (2) EP2931875B1 (enExample)
JP (2) JP6404227B2 (enExample)
KR (2) KR102151588B1 (enExample)
CN (2) CN105026551B (enExample)
AR (2) AR093985A1 (enExample)
AU (2) AU2013359265B2 (enExample)
BR (1) BR112015013685A8 (enExample)
CA (1) CA2895079C (enExample)
ES (1) ES2667573T3 (enExample)
MX (2) MX364731B (enExample)
PH (1) PH12015501310B1 (enExample)
PL (1) PL2931875T3 (enExample)
RU (2) RU2684306C2 (enExample)
SG (2) SG11201504547SA (enExample)
TW (1) TWI620818B (enExample)
WO (1) WO2014093598A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10791730B2 (en) * 2016-01-14 2020-10-06 DePuy Synthes Products, Inc. Composition and methods for cryopreservation of hUTC
US10894947B1 (en) * 2016-04-29 2021-01-19 Hope Biosciences, Llc Method for generating protein rich conditioned medium
US11111480B2 (en) 2016-04-29 2021-09-07 Hope Biosctences, Llc Culture media for multipotent stem cells
CN106434532A (zh) * 2016-12-22 2017-02-22 叶宗耀 一种培养肝细胞的培养基及其制备方法
CN106957815B (zh) * 2017-03-16 2021-05-07 杨涛 一种用于人类多潜能干细胞的无血清培养基的配方
JP7181534B2 (ja) * 2017-03-28 2022-12-01 味の素株式会社 未分化維持培地添加剤
CN107119017B (zh) * 2017-05-25 2020-05-26 山东省医药生物技术研究中心 一种骨肉瘤细胞的无血清培养基及其制备方法
KR20210068488A (ko) * 2018-09-28 2021-06-09 아지노모토 가부시키가이샤 동물 세포의 배양용 첨가물, 배양용 배지 및 배양 방법
EP3947642A4 (en) * 2019-04-05 2022-12-14 The University of Hong Kong CULTURE MEDIUM FOR MAMMALIAN PLURIPOTENTE STEM CELLS, COMPOSITION AND METHODS
WO2020219812A1 (en) 2019-04-26 2020-10-29 Allogene Therapeutics, Inc. Methods of manufacturing allogeneic car t cells
EP3983481A1 (en) * 2019-06-13 2022-04-20 Corning Incorporated Dissolvable microcarriers for culturing cells and related methods
CN114058573B (zh) * 2020-08-03 2024-04-05 上海原天生物科技有限公司 一种含有生物素的培养基
CN112608892B (zh) * 2020-12-25 2023-11-14 深圳博雅感知药业有限公司 血小板裂解物用于无血清分离和传代培养脐带间充质干细胞的方法
KR20220104321A (ko) 2021-01-18 2022-07-26 주식회사 엑소코바이오 엑소좀 및/또는 세포외 소포체의 생성 촉진 내지는 생산성 향상 방법
US11735303B2 (en) 2021-06-22 2023-08-22 David Haase Apparatus and method for determining a composition of a replacement therapy treatment
WO2024253069A1 (ja) * 2023-06-06 2024-12-12 東ソー株式会社 温度応答性マイクロキャリア
KR20250140345A (ko) * 2024-03-18 2025-09-25 주식회사 심플플래닛 세포 증식 활성이 우수한 식용 배지 조성물

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA776251B (en) * 1976-11-11 1978-07-26 Massachusetts Inst Technology Improved cell culture microcarriers
WO1991010726A1 (en) * 1990-01-22 1991-07-25 The United States Of America, Represented By The Secretary, United States Department Of Commerce Co-independent growth medium for maintenance and propagation of cells
JP2993614B2 (ja) * 1990-11-20 1999-12-20 有限会社野々川商事 新規化粧料、グルコサミノグリカン生成促進剤および美白剤
US7556958B1 (en) 1997-04-08 2009-07-07 The Rockefeller University Enzyme derived from thermophilic organisms that functions as a chromosomal replicase, and preparation and uses thereof
CA2438148A1 (en) * 2001-02-15 2002-08-29 Centocor, Inc. Chemically defined medium for cultured mammalian cells
US9969980B2 (en) 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
WO2003057865A1 (es) * 2002-01-09 2003-07-17 Derbiotek, S.L. Composicion y procedimiento para crear, regenerar y reparar tejidos mediante implante biologico portador de celulas y enriquecido con concentrado de plaquetas mas suplementos.
US8518390B2 (en) * 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
CA2530421C (en) 2003-06-27 2015-04-21 Ethicon, Incorporated Repair and regeneration of ocular tissue using postpartum-derived cells
US20050005863A1 (en) 2003-07-10 2005-01-13 Snider Tracy Aurora Christine Distillers solubles as the primary constituent in protein blocks for livestock
EP1682075A4 (en) * 2003-11-07 2009-12-09 Univ Florida BREEDING AND DIFFERENTIATION OF NEURAL CREATOR CELLS
JP2008518597A (ja) * 2004-10-29 2008-06-05 セントカー・インコーポレーテツド 化学的規定培地組成物
JP5340599B2 (ja) * 2004-12-23 2013-11-13 エシコン・インコーポレイテッド 臍帯組織由来産褥細胞ならびにその製造方法および使用方法
JP5179376B2 (ja) 2005-12-19 2013-04-10 エシコン・インコーポレイテッド ローラーボトルでの分娩後取り出し細胞の体外増殖
AU2007270069B2 (en) * 2006-07-06 2013-05-16 Es Cell International Pte Ltd Method for stem cell culture and cells derived therefrom
ES2524443T3 (es) * 2006-11-13 2014-12-09 DePuy Synthes Products, LLC Expansión in vitro de células postparto usando microportadores
US20100143289A1 (en) * 2006-12-19 2010-06-10 Michael Cohen Umbilical cord stem cell secreted product derived topical compositions and methods of use thereof
EP2028268A1 (en) * 2007-08-20 2009-02-25 Université Libre De Bruxelles Generation of neuronal cells from pluripotent stem cells
CN100482783C (zh) * 2007-11-27 2009-04-29 天津百若克医药生物技术有限责任公司 一种用于Vero细胞的培养基及其培养方法
US10179900B2 (en) * 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
JP2013500717A (ja) * 2009-07-28 2013-01-10 コーニング インコーポレイテッド 細胞を培養するための合成マイクロキャリア

Also Published As

Publication number Publication date
AU2013359265B2 (en) 2019-01-31
AR118040A2 (es) 2021-09-15
HK1215050A1 (en) 2016-08-12
CA2895079A1 (en) 2014-06-19
JP2018183195A (ja) 2018-11-22
ES2667573T3 (es) 2018-05-11
US20140170748A1 (en) 2014-06-19
CN111690602A (zh) 2020-09-22
BR112015013685A8 (pt) 2019-11-05
EP2931875B1 (en) 2018-03-21
MX364731B (es) 2019-05-06
TW201439321A (zh) 2014-10-16
SG10201801924VA (en) 2018-05-30
KR101948237B1 (ko) 2019-02-14
SG11201504547SA (en) 2015-07-30
EP3382007A1 (en) 2018-10-03
CN105026551B (zh) 2020-07-03
JP2016501026A (ja) 2016-01-18
PH12015501310A1 (en) 2015-09-02
PL2931875T3 (pl) 2018-08-31
TWI620818B (zh) 2018-04-11
AU2013359265A1 (en) 2015-07-16
RU2018112452A (ru) 2019-03-01
JP6404227B2 (ja) 2018-10-10
WO2014093598A1 (en) 2014-06-19
MX2018013469A (es) 2020-11-12
RU2684306C2 (ru) 2019-04-05
KR20190016612A (ko) 2019-02-18
RU2653449C2 (ru) 2018-05-08
AU2019202191B2 (en) 2021-01-21
RU2015128276A (ru) 2017-01-23
BR112015013685A2 (pt) 2017-07-11
MX2015007594A (es) 2016-03-15
EP2931875A1 (en) 2015-10-21
CN105026551A (zh) 2015-11-04
JP6595061B2 (ja) 2019-10-23
KR102151588B1 (ko) 2020-09-04
RU2018112452A3 (enExample) 2019-03-01
KR20150094760A (ko) 2015-08-19
AR093985A1 (es) 2015-07-01
CA2895079C (en) 2021-06-29
AU2019202191A1 (en) 2019-04-18

Similar Documents

Publication Publication Date Title
AU2019202191B2 (en) Nutrient enriched media for hUTC growth
KR102211270B1 (ko) Hutc의 동결보존을 위한 조성물 및 방법
US10724105B2 (en) Detection of human umbilical cord tissue-derived cells
HK1215050B (en) Nutrient enriched media for hutc growth