KR102151588B1 - hUTC 성장을 위한 영양 강화 배지 - Google Patents

hUTC 성장을 위한 영양 강화 배지 Download PDF

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Publication number
KR102151588B1
KR102151588B1 KR1020197003828A KR20197003828A KR102151588B1 KR 102151588 B1 KR102151588 B1 KR 102151588B1 KR 1020197003828 A KR1020197003828 A KR 1020197003828A KR 20197003828 A KR20197003828 A KR 20197003828A KR 102151588 B1 KR102151588 B1 KR 102151588B1
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cells
medium
cell
culture
microcarriers
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KR20190016612A (ko
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라빈더 바티아
엘.에스. 클라우디네 홍
사데틴 에스. 오즈투르크
벤캇 에이치. 카마라주
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디퍼이 신테스 프로덕츠, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C12N5/0075—General culture methods using substrates using microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020197003828A 2012-12-14 2013-12-12 hUTC 성장을 위한 영양 강화 배지 Expired - Fee Related KR102151588B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/715,532 US20140170748A1 (en) 2012-12-14 2012-12-14 Nutrient Enriched Media for hUTC Growth
US13/715,532 2012-12-14
PCT/US2013/074615 WO2014093598A1 (en) 2012-12-14 2013-12-12 NUTRIENT ENRICHED MEDIA FOR hUTC GROWTH

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020157018827A Division KR101948237B1 (ko) 2012-12-14 2013-12-12 hUTC 성장을 위한 영양 강화 배지

Publications (2)

Publication Number Publication Date
KR20190016612A KR20190016612A (ko) 2019-02-18
KR102151588B1 true KR102151588B1 (ko) 2020-09-04

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KR1020197003828A Expired - Fee Related KR102151588B1 (ko) 2012-12-14 2013-12-12 hUTC 성장을 위한 영양 강화 배지
KR1020157018827A Expired - Fee Related KR101948237B1 (ko) 2012-12-14 2013-12-12 hUTC 성장을 위한 영양 강화 배지

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KR1020157018827A Expired - Fee Related KR101948237B1 (ko) 2012-12-14 2013-12-12 hUTC 성장을 위한 영양 강화 배지

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Country Link
US (1) US20140170748A1 (enExample)
EP (2) EP3382007A1 (enExample)
JP (2) JP6404227B2 (enExample)
KR (2) KR102151588B1 (enExample)
CN (2) CN111690602A (enExample)
AR (2) AR093985A1 (enExample)
AU (2) AU2013359265B2 (enExample)
BR (1) BR112015013685A8 (enExample)
CA (1) CA2895079C (enExample)
ES (1) ES2667573T3 (enExample)
MX (2) MX364731B (enExample)
PH (1) PH12015501310B1 (enExample)
PL (1) PL2931875T3 (enExample)
RU (2) RU2684306C2 (enExample)
SG (2) SG10201801924VA (enExample)
TW (1) TWI620818B (enExample)
WO (1) WO2014093598A1 (enExample)

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CN108471736A (zh) 2016-01-14 2018-08-31 德普伊新特斯产品公司 用于冷冻保存hutc的组合物和方法
US10894947B1 (en) * 2016-04-29 2021-01-19 Hope Biosciences, Llc Method for generating protein rich conditioned medium
US11111480B2 (en) 2016-04-29 2021-09-07 Hope Biosctences, Llc Culture media for multipotent stem cells
CN106434532A (zh) * 2016-12-22 2017-02-22 叶宗耀 一种培养肝细胞的培养基及其制备方法
CN106957815B (zh) * 2017-03-16 2021-05-07 杨涛 一种用于人类多潜能干细胞的无血清培养基的配方
CN110494559B (zh) * 2017-03-28 2023-10-31 味之素株式会社 不分化地维持用培养基添加剂
CN107119017B (zh) * 2017-05-25 2020-05-26 山东省医药生物技术研究中心 一种骨肉瘤细胞的无血清培养基及其制备方法
JPWO2020067502A1 (ja) * 2018-09-28 2021-08-30 味の素株式会社 動物細胞の培養用添加物、培養用培地および培養方法
US20220145264A1 (en) * 2019-04-05 2022-05-12 The University Of Hong Kong Culture medium for mammalian expanded potential stem cells, composition, and methods thereof
JP7650818B2 (ja) 2019-04-26 2025-03-25 アロジーン セラピューティクス，インコーポレイテッド 同種ｃａｒ ｔ細胞を製造する方法
EP3983481A1 (en) * 2019-06-13 2022-04-20 Corning Incorporated Dissolvable microcarriers for culturing cells and related methods
CN114058573B (zh) * 2020-08-03 2024-04-05 上海原天生物科技有限公司 一种含有生物素的培养基
CN112608892B (zh) * 2020-12-25 2023-11-14 深圳博雅感知药业有限公司 血小板裂解物用于无血清分离和传代培养脐带间充质干细胞的方法
KR20220104321A (ko) 2021-01-18 2022-07-26 주식회사 엑소코바이오 엑소좀 및/또는 세포외 소포체의 생성 촉진 내지는 생산성 향상 방법
US11735303B2 (en) 2021-06-22 2023-08-22 David Haase Apparatus and method for determining a composition of a replacement therapy treatment
JPWO2024253069A1 (enExample) * 2023-06-06 2024-12-12
KR20250140345A (ko) * 2024-03-18 2025-09-25 주식회사 심플플래닛 세포 증식 활성이 우수한 식용 배지 조성물

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Also Published As

Publication number Publication date
KR20190016612A (ko) 2019-02-18
EP2931875A1 (en) 2015-10-21
HK1215050A1 (en) 2016-08-12
AR093985A1 (es) 2015-07-01
MX364731B (es) 2019-05-06
AU2013359265B2 (en) 2019-01-31
RU2684306C2 (ru) 2019-04-05
WO2014093598A1 (en) 2014-06-19
AU2019202191B2 (en) 2021-01-21
JP2018183195A (ja) 2018-11-22
US20140170748A1 (en) 2014-06-19
AR118040A2 (es) 2021-09-15
AU2019202191A1 (en) 2019-04-18
RU2653449C2 (ru) 2018-05-08
JP6404227B2 (ja) 2018-10-10
RU2018112452A (ru) 2019-03-01
MX2015007594A (es) 2016-03-15
MX2018013469A (es) 2020-11-12
RU2018112452A3 (enExample) 2019-03-01
SG11201504547SA (en) 2015-07-30
CN105026551B (zh) 2020-07-03
KR20150094760A (ko) 2015-08-19
JP6595061B2 (ja) 2019-10-23
EP3382007A1 (en) 2018-10-03
CN111690602A (zh) 2020-09-22
JP2016501026A (ja) 2016-01-18
PH12015501310A1 (en) 2015-09-02
CA2895079C (en) 2021-06-29
CN105026551A (zh) 2015-11-04
BR112015013685A8 (pt) 2019-11-05
ES2667573T3 (es) 2018-05-11
PH12015501310B1 (en) 2015-09-02
KR101948237B1 (ko) 2019-02-14
CA2895079A1 (en) 2014-06-19
RU2015128276A (ru) 2017-01-23
BR112015013685A2 (pt) 2017-07-11
PL2931875T3 (pl) 2018-08-31
EP2931875B1 (en) 2018-03-21
TW201439321A (zh) 2014-10-16
TWI620818B (zh) 2018-04-11
SG10201801924VA (en) 2018-05-30
AU2013359265A1 (en) 2015-07-16

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