PE20061040A1 - Anticuerpos antiamiloides humanizados - Google Patents
Anticuerpos antiamiloides humanizadosInfo
- Publication number
- PE20061040A1 PE20061040A1 PE2006000102A PE2006000102A PE20061040A1 PE 20061040 A1 PE20061040 A1 PE 20061040A1 PE 2006000102 A PE2006000102 A PE 2006000102A PE 2006000102 A PE2006000102 A PE 2006000102A PE 20061040 A1 PE20061040 A1 PE 20061040A1
- Authority
- PE
- Peru
- Prior art keywords
- seq
- humanized
- amino acid
- antibodies
- antiamylloid
- Prior art date
Links
- 150000001413 amino acids Chemical group 0.000 abstract 3
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 2
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 2
- 239000011230 binding agent Substances 0.000 abstract 2
- 230000009870 specific binding Effects 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 102000009091 Amyloidogenic Proteins Human genes 0.000 abstract 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 abstract 1
- 230000003942 amyloidogenic effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0312—Animal model for Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
REFERIDA A UN AGENTE DE UNION ESPECIFICO AISLADO QUE SE UNE AL BETA - AMILOIDE, QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS AL MENOS 80% IDENTICA A LA SECUENCIA DE AMINOACIDOS ESTABLECIDA EN SEQ ID NO: 11; ADEMAS, PUEDE COMPRENDER LAS SECUENCIAS DE AMINOACIDOS DE SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NOS. 12, 13 O 14, ENTRE OTRAS. DICHOS AGENTES DE UNION ESPECIFICOS SON ANTICUERPOS MONOCLONALES HUMANOS O HUMANIZADOS (NO MURINOS) QUE SE UNEN AL BETA - AMILOIDE Y SON UTILES PARA EL TRATAMIENTO DE TRASTORNOS NEURODEGENERATIVOS O AMILOIDOGENICOS TALES COMO LA ENFERMEDAD DE ALZHEIMER
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64665805P | 2005-01-24 | 2005-01-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20061040A1 true PE20061040A1 (es) | 2006-10-12 |
Family
ID=36463459
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2006000102A PE20061040A1 (es) | 2005-01-24 | 2006-01-24 | Anticuerpos antiamiloides humanizados |
Country Status (8)
Country | Link |
---|---|
US (1) | US7906625B2 (es) |
EP (1) | EP1841455A1 (es) |
AU (1) | AU2006208226A1 (es) |
CA (1) | CA2589860A1 (es) |
PA (1) | PA8660801A1 (es) |
PE (1) | PE20061040A1 (es) |
UY (1) | UY29344A1 (es) |
WO (1) | WO2006081171A1 (es) |
Families Citing this family (164)
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WO2008001505A1 (fr) * | 2006-06-30 | 2008-01-03 | Hokkaido System Science Co., Ltd. | Composition pour la pénétration d'acides nucléiques |
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- 2006-01-23 US US11/576,220 patent/US7906625B2/en not_active Expired - Fee Related
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PA8660801A1 (es) | 2006-10-13 |
AU2006208226A1 (en) | 2006-08-03 |
WO2006081171A1 (en) | 2006-08-03 |
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