PA8660801A1 - Anticuerpos antiamiloides humanizados - Google Patents

Anticuerpos antiamiloides humanizados

Info

Publication number
PA8660801A1
PA8660801A1 PA20068660801A PA8660801A PA8660801A1 PA 8660801 A1 PA8660801 A1 PA 8660801A1 PA 20068660801 A PA20068660801 A PA 20068660801A PA 8660801 A PA8660801 A PA 8660801A PA 8660801 A1 PA8660801 A1 PA 8660801A1
Authority
PA
Panama
Prior art keywords
antibodies
humanized
antiamiloid
compositions
anibete
Prior art date
Application number
PA20068660801A
Other languages
English (en)
Inventor
Wenyan Shen
Anja Leona Biere-Citron
Original Assignee
Amgen Inc Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc Amgen Inc filed Critical Amgen Inc Amgen Inc
Publication of PA8660801A1 publication Critical patent/PA8660801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A01K2267/0312—Animal model for Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PROPORCIONAN COMPOSICIONES PARA TRAAR TRASTORNOS NEURODEGENERATIVOS O AMILOIDOGENICOS, TALES COMO LA ENFERMEDAD DE ALZHEIMER (EA). MAS ESPECIFICAMENTE, SE PROPORCIONAN ANTICUERPOS ANIBETE-AMILOIDES HUMANIZADOS, COMPOSICIONES QUE CONIENEN DICHOS ANTICUERPOS, LOS CORREPONDIENTES ACIDOS NUCLEICOS, VECORES Y CELULAS HUESPED, Y METODOS DE PREPAR DICHOS ANTICUERPOS.
PA20068660801A 2005-01-24 2006-01-24 Anticuerpos antiamiloides humanizados PA8660801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64665805P 2005-01-24 2005-01-24

Publications (1)

Publication Number Publication Date
PA8660801A1 true PA8660801A1 (es) 2006-10-13

Family

ID=36463459

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20068660801A PA8660801A1 (es) 2005-01-24 2006-01-24 Anticuerpos antiamiloides humanizados

Country Status (8)

Country Link
US (1) US7906625B2 (es)
EP (1) EP1841455A1 (es)
AU (1) AU2006208226A1 (es)
CA (1) CA2589860A1 (es)
PA (1) PA8660801A1 (es)
PE (1) PE20061040A1 (es)
UY (1) UY29344A1 (es)
WO (1) WO2006081171A1 (es)

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