OA12244A - Oxazole derivatives and their uses as tyrosine kinase inhibitors. - Google Patents
Oxazole derivatives and their uses as tyrosine kinase inhibitors. Download PDFInfo
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- OA12244A OA12244A OA1200200311A OA1200200311A OA12244A OA 12244 A OA12244 A OA 12244A OA 1200200311 A OA1200200311 A OA 1200200311A OA 1200200311 A OA1200200311 A OA 1200200311A OA 12244 A OA12244 A OA 12244A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000106836 | 2000-04-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA12244A true OA12244A (en) | 2006-05-10 |
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Family Applications (1)
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| OA1200200311A OA12244A (en) | 2000-04-07 | 2001-04-05 | Oxazole derivatives and their uses as tyrosine kinase inhibitors. |
Country Status (19)
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| US (2) | US6716863B2 (cs) |
| EP (1) | EP1268473A1 (cs) |
| KR (1) | KR20020028865A (cs) |
| CN (1) | CN1444582A (cs) |
| AU (1) | AU2001244726A1 (cs) |
| BR (1) | BR0109851A (cs) |
| CA (1) | CA2404760A1 (cs) |
| CO (1) | CO5261589A1 (cs) |
| CZ (1) | CZ20023264A3 (cs) |
| EE (1) | EE200200576A (cs) |
| HU (1) | HUP0300434A3 (cs) |
| IL (1) | IL152115A0 (cs) |
| MX (1) | MXPA02009621A (cs) |
| NO (1) | NO20024742L (cs) |
| OA (1) | OA12244A (cs) |
| PE (1) | PE20011178A1 (cs) |
| PL (1) | PL365787A1 (cs) |
| SK (1) | SK14132002A3 (cs) |
| WO (1) | WO2001077107A1 (cs) |
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| EP1136079A4 (en) * | 1998-10-08 | 2004-09-22 | Takeda Chemical Industries Ltd | AGENTS FOR DELAYING THE TRANSFER FROM HORMONO-DEPENDENT CANCER TO HORMONO-INDEPENDENT CANCER |
| CA2415961A1 (en) * | 2000-07-19 | 2002-01-24 | Hirohiko Nishiyama | Production method of 1-substituted-1,2,3-triazole derivatives |
| CA2444727A1 (en) * | 2001-04-25 | 2002-11-07 | Takeda Chemical Industries, Ltd. | Agents for preventing postoperative recurrence of premenopausal breast cancer |
| WO2002087619A1 (en) * | 2001-04-27 | 2002-11-07 | Takeda Chemical Industries, Ltd. | Preventive/therapeutic method for cancer |
| US20040116330A1 (en) * | 2001-04-27 | 2004-06-17 | Kenichiro Naito | Preventive/therapeutic method for cancer |
| EP1424080B1 (en) * | 2001-08-10 | 2011-02-16 | Takeda Pharmaceutical Company Limited | Gnrh agonist combination drugs |
| EP1439178A4 (en) * | 2001-10-05 | 2005-11-16 | Takeda Pharmaceutical | Heterocyclic compounds, oxazole derivatives, process for their preparation and their use |
| CA2466659A1 (en) | 2001-11-13 | 2003-05-22 | Takeda Chemical Industries, Ltd. | Anticancer agents |
| EP1460067A4 (en) * | 2001-11-26 | 2005-12-07 | Takeda Pharmaceutical | BICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE |
| AU2003203170A1 (en) * | 2002-01-17 | 2003-07-30 | Takeda Chemical Industries, Ltd. | Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof |
| WO2003090686A2 (en) | 2002-04-25 | 2003-11-06 | University Of Connecticut Health Center | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
| UA85359C2 (ru) * | 2002-12-16 | 2009-01-12 | Киссеи Фармасьютикал Ко., Лтд. | Таблетка, содержащая гранулированный материал с kmd-3213 |
| TW200505913A (en) | 2003-03-28 | 2005-02-16 | Hoffmann La Roche | Novel oxazole derivatives, their manufacture and use as pharmaceutical agents |
| AR044098A1 (es) * | 2003-04-30 | 2005-08-24 | Hoffmann La Roche | Derivados de anilina, su elaboracion, composiciones farmaceuticas y su uso para elaborar medicamentos para el tratamiento del cancer |
| US7247649B2 (en) * | 2003-08-13 | 2007-07-24 | Hoffmann-La Roche Inc. | Oxazoles, their manufacture and use as pharmaceutical agents |
| US7259262B2 (en) | 2003-10-24 | 2007-08-21 | Hoffmann-La Roche Inc. | Arylazole derivatives, their manufacture and use as pharmaceutical agents |
| US20050186275A1 (en) * | 2004-02-23 | 2005-08-25 | Standard Chem. & Pharm. Co. Ltd. | Sustained release tamsulosin formulations |
| TW200531688A (en) | 2004-03-05 | 2005-10-01 | Hoffmann La Roche | Novel pentafluorosulfanyl compounds, their manufacture and use as pharmaceutical agents |
| TW200612914A (en) | 2004-03-05 | 2006-05-01 | Hoffmann La Roche | Novel oxidized thioether derivatives, their manufacture and use as pharmaceutical agents |
| TW200533346A (en) | 2004-03-18 | 2005-10-16 | Hoffmann La Roche | Novel ether derivatives, their manufacture and use as pharmaceutical agents |
| KR100843533B1 (ko) * | 2004-04-02 | 2008-07-03 | 에프. 호프만-라 로슈 아게 | 신규한 디아진 유도체, 이의 제조 및 약학적 제제로서의용도 |
| US7163953B2 (en) * | 2004-05-25 | 2007-01-16 | Hoffmann-La Roche Inc. | Benzylether derivatives |
| US7005526B2 (en) * | 2004-05-25 | 2006-02-28 | Hoffmann-La Roche Inc. | Thioether derivatives |
| US7618769B2 (en) * | 2004-06-07 | 2009-11-17 | Applied Materials, Inc. | Textured chamber surface |
| US7288557B2 (en) | 2004-09-21 | 2007-10-30 | Hoffmann-La Roche Inc. | Triazole derivatives |
| AR050944A1 (es) | 2004-09-22 | 2006-12-06 | Hoffmann La Roche | Derivados de indol, su fabricacion y su utilizacion como agentes farmaceuticos |
| AR050652A1 (es) * | 2004-09-24 | 2006-11-08 | Hoffmann La Roche | Derivados de oxazol, preparacion y uso como inhibidores de la tirosina quinasa |
| US20060116407A1 (en) * | 2004-11-22 | 2006-06-01 | Birgit Bossenmaier | Amide derivatives |
| TW200727900A (en) * | 2005-07-27 | 2007-08-01 | Yakult Honsha Kk | Aqueous solution preparation containing camptothecins |
| TW200738680A (en) * | 2005-08-04 | 2007-10-16 | Hoffmann La Roche | Phenylpyridine derivatives, their manufacture and use as pharmaceutical agents |
| JP2009504586A (ja) * | 2005-08-08 | 2009-02-05 | エフ.ホフマン−ラ ロシュ アーゲー | ピラゾール誘導体、それらの製造及び医薬品としての使用 |
| JP2009509998A (ja) * | 2005-09-30 | 2009-03-12 | エフ.ホフマン−ラ ロシュ アーゲー | ジアジンアゾール誘導体、それらの製造及び薬剤としての使用 |
| WO2008034579A1 (en) * | 2006-09-20 | 2008-03-27 | F. Hoffmann-La Roche Ag | 2-heterocyclyl-5-phenoxymethylpyridine derivatives as anticancer agents |
| CN101611041A (zh) | 2006-12-12 | 2009-12-23 | 武田药品工业株式会社 | 稠合杂环化合物 |
| CN101657216B (zh) | 2007-04-20 | 2012-11-21 | 大同化成工业株式会社 | 干式固体分散体用基剂、含有该基剂的固体分散体及含有该分散体的组合物 |
| JPWO2009113560A1 (ja) | 2008-03-12 | 2011-07-21 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| TW201016704A (en) * | 2008-09-26 | 2010-05-01 | Takeda Pharmaceutical | Prevention and treatment of cancer with RAS gene mutation |
| AR073679A1 (es) * | 2008-09-26 | 2010-11-24 | Takeda Pharmaceutical | Prevencion y tratamiento de cancer con la no expresion de lkb1 supresion o mutacion, composicion farmaceutica. usos |
| US9023398B2 (en) | 2009-09-30 | 2015-05-05 | Kabushiki Kaisha Sangi | Method for improving the aqueous solubility of poorly-soluble substances |
| JP5705206B2 (ja) | 2010-02-26 | 2015-04-22 | 日新化成株式会社 | 硬カプセルおよびその製造方法 |
| WO2011153049A1 (en) | 2010-06-02 | 2011-12-08 | The Trustees Of The University Of Pennsylvania | Methods and use of compounds that bind to her2/neu receptor complex |
| US9265739B2 (en) | 2010-06-02 | 2016-02-23 | The Trustees Of The University Of Pennsylvania | Methods and use of compounds that bind to HER2/neu receptor complex |
| JP5909796B2 (ja) | 2012-03-02 | 2016-04-27 | 株式会社サンギ | 難溶性物質の水溶解性改善方法 |
| EP2902014B1 (en) | 2012-09-26 | 2019-03-06 | Takeda Pharmaceutical Company Limited | Process for producing solid particles |
| US9468681B2 (en) | 2013-03-01 | 2016-10-18 | California Institute Of Technology | Targeted nanoparticles |
| CN111643479B (zh) | 2015-07-01 | 2023-10-27 | 加州理工学院 | 基于阳离子粘酸聚合物的递送系统 |
| EP3238711B1 (en) | 2016-04-26 | 2023-07-12 | Mitsubishi Chemical Corporation | Base for solid dispersion, production method for solid dispersion using same, and solid dispersion |
| CA2995617A1 (en) * | 2017-11-03 | 2019-05-03 | Universite De Montreal | Heterocyclic mitochondrial activity inhibitors and uses thereof |
| JP7483193B2 (ja) | 2018-06-13 | 2024-05-15 | カリフォルニア・インスティテュート・オブ・テクノロジー | 血脳バリアを越えるためのナノ粒子とそれを用いた治療法 |
| JPWO2020130125A1 (ja) | 2018-12-21 | 2021-11-04 | 第一三共株式会社 | 抗体−薬物コンジュゲートとキナーゼ阻害剤の組み合わせ |
| EP4073102A4 (en) | 2019-12-12 | 2024-05-08 | Ting Therapeutics LLC | Compositions and methods for the prevention and treatment of hearing loss |
| CN114217025B (zh) * | 2021-12-17 | 2024-01-23 | 哈尔滨工业大学 | 评估空气质量浓度预测中气象数据对其影响的分析方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0525109A4 (en) | 1990-04-16 | 1993-06-30 | Rhone-Poulenc Rorer International (Holdings) Inc. | Styryl-substituted monocyclic and bicyclic heteroaryl compounds which inhibit egf receptor tyrosine kinase |
| CN1077107C (zh) * | 1996-07-19 | 2002-01-02 | 武田药品工业株式会社 | 杂环化合物、其制备和用途 |
-
2001
- 2001-04-03 PE PE2001000307A patent/PE20011178A1/es not_active Application Discontinuation
- 2001-04-05 CZ CZ20023264A patent/CZ20023264A3/cs unknown
- 2001-04-05 OA OA1200200311A patent/OA12244A/en unknown
- 2001-04-05 HU HU0300434A patent/HUP0300434A3/hu unknown
- 2001-04-05 SK SK1413-2002A patent/SK14132002A3/sk unknown
- 2001-04-05 EP EP01917827A patent/EP1268473A1/en not_active Withdrawn
- 2001-04-05 AU AU2001244726A patent/AU2001244726A1/en not_active Abandoned
- 2001-04-05 BR BR0109851-9A patent/BR0109851A/pt not_active Application Discontinuation
- 2001-04-05 CA CA002404760A patent/CA2404760A1/en not_active Abandoned
- 2001-04-05 EE EEP200200576A patent/EE200200576A/xx unknown
- 2001-04-05 IL IL15211501A patent/IL152115A0/xx unknown
- 2001-04-05 KR KR1020017011568A patent/KR20020028865A/ko not_active Abandoned
- 2001-04-05 MX MXPA02009621A patent/MXPA02009621A/es unknown
- 2001-04-05 PL PL01365787A patent/PL365787A1/xx not_active Application Discontinuation
- 2001-04-05 WO PCT/JP2001/002937 patent/WO2001077107A1/en not_active Ceased
- 2001-04-05 CN CN01807792A patent/CN1444582A/zh active Pending
- 2001-04-05 US US09/889,974 patent/US6716863B2/en not_active Expired - Fee Related
- 2001-04-06 CO CO01027571A patent/CO5261589A1/es not_active Application Discontinuation
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2002
- 2002-10-02 NO NO20024742A patent/NO20024742L/no not_active Application Discontinuation
-
2003
- 2003-07-17 US US10/620,706 patent/US20040024035A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6716863B2 (en) | 2004-04-06 |
| US20020173526A1 (en) | 2002-11-21 |
| WO2001077107B1 (en) | 2001-12-20 |
| PE20011178A1 (es) | 2001-11-19 |
| PL365787A1 (en) | 2005-01-10 |
| EP1268473A1 (en) | 2003-01-02 |
| NO20024742D0 (no) | 2002-10-02 |
| BR0109851A (pt) | 2003-06-03 |
| HUP0300434A3 (en) | 2004-11-29 |
| EE200200576A (et) | 2004-06-15 |
| KR20020028865A (ko) | 2002-04-17 |
| WO2001077107A8 (en) | 2003-02-13 |
| AU2001244726A1 (en) | 2001-10-23 |
| CA2404760A1 (en) | 2001-10-18 |
| MXPA02009621A (es) | 2003-05-14 |
| CO5261589A1 (es) | 2003-03-31 |
| HUP0300434A2 (hu) | 2003-06-28 |
| CZ20023264A3 (cs) | 2003-02-12 |
| NO20024742L (no) | 2002-11-25 |
| IL152115A0 (en) | 2003-05-29 |
| US20040024035A1 (en) | 2004-02-05 |
| WO2001077107A1 (en) | 2001-10-18 |
| SK14132002A3 (sk) | 2003-04-01 |
| CN1444582A (zh) | 2003-09-24 |
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