NZ727418A - 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor - Google Patents

1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor

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Publication number
NZ727418A
NZ727418A NZ727418A NZ72741815A NZ727418A NZ 727418 A NZ727418 A NZ 727418A NZ 727418 A NZ727418 A NZ 727418A NZ 72741815 A NZ72741815 A NZ 72741815A NZ 727418 A NZ727418 A NZ 727418A
Authority
NZ
New Zealand
Prior art keywords
diseases
trka kinase
kinase inhibitor
methylpyrimidin
pyrazol
Prior art date
Application number
NZ727418A
Other languages
English (en)
Inventor
Shelley Allen
Steven Andrews
Brian Baer
Zackary Crane
Weidong Liu
Daniel John Watson
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of NZ727418A publication Critical patent/NZ727418A/en

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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NZ727418A 2014-05-15 2015-05-14 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor NZ727418A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461993426P 2014-05-15 2014-05-15
PCT/US2015/030795 WO2015175788A1 (en) 2014-05-15 2015-05-14 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor

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NZ727418A true NZ727418A (en) 2023-03-31

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PL3154959T3 (pl) 2019-12-31
KR102321883B1 (ko) 2021-11-03
LT3154959T (lt) 2019-09-25
US20170087156A1 (en) 2017-03-30
RU2719489C2 (ru) 2020-04-17
MX2019012600A (es) 2019-12-16
KR101998461B1 (ko) 2019-07-09
JP6499672B2 (ja) 2019-04-10
CL2016002900A1 (es) 2017-04-28
SI3154959T1 (sl) 2019-10-30
PT3154959T (pt) 2019-09-24
IL248924A0 (en) 2017-01-31
CN106459013A (zh) 2017-02-22
WO2015175788A1 (en) 2015-11-19
BR112016026672A2 (pt) 2017-08-15
AU2015259075A1 (en) 2017-01-12
PH12016502242A1 (en) 2017-01-09
JP2017518981A (ja) 2017-07-13
EP3154959A1 (en) 2017-04-19
PH12020500171A1 (en) 2021-02-08
MY191956A (en) 2022-07-20
AU2019201400A1 (en) 2019-03-21
RU2016149233A3 (enExample) 2018-12-03
UA122126C2 (uk) 2020-09-25
ES2746530T3 (es) 2020-03-06
HRP20191593T1 (hr) 2019-11-29
CA2949160C (en) 2023-03-21
AU2015259075B2 (en) 2019-01-24
IL248924B (en) 2020-01-30
CN109970614A (zh) 2019-07-05
US10835533B2 (en) 2020-11-17
PH12016502242B1 (en) 2017-01-09
KR20170005856A (ko) 2017-01-16
CN106459013B (zh) 2019-10-25

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