CR20160583A - 1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)urea como inhibidor de trka cinasa - Google Patents

1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)urea como inhibidor de trka cinasa

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Publication number
CR20160583A
CR20160583A CR20160583A CR20160583A CR20160583A CR 20160583 A CR20160583 A CR 20160583A CR 20160583 A CR20160583 A CR 20160583A CR 20160583 A CR20160583 A CR 20160583A CR 20160583 A CR20160583 A CR 20160583A
Authority
CR
Costa Rica
Prior art keywords
diseases
trka
inhibitor
methylpirimidin
cinasa
Prior art date
Application number
CR20160583A
Other languages
English (en)
Spanish (es)
Inventor
Steven W Andrews
Shelley Allen
Zackary Crane
Brian Baer
Weidong Liu
Daniel John Watson
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of CR20160583A publication Critical patent/CR20160583A/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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CR20160583A 2014-05-15 2015-05-14 1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)urea como inhibidor de trka cinasa CR20160583A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461993426P 2014-05-15 2014-05-15
PCT/US2015/030795 WO2015175788A1 (en) 2014-05-15 2015-05-14 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor

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CR20160583A true CR20160583A (es) 2017-02-23

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CR20160583A CR20160583A (es) 2014-05-15 2015-05-14 1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)urea como inhibidor de trka cinasa

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CN109970614A (zh) 2019-07-05
IL248924A0 (en) 2017-01-31
EP3564236A1 (en) 2019-11-06
KR101998461B1 (ko) 2019-07-09
RU2719489C2 (ru) 2020-04-17
EP3154959A1 (en) 2017-04-19
JP6499672B2 (ja) 2019-04-10
CN106459013B (zh) 2019-10-25
BR112016026672A8 (pt) 2021-07-20
JP2019085427A (ja) 2019-06-06
EP3154959B1 (en) 2019-07-10
SI3154959T1 (sl) 2019-10-30
US10835533B2 (en) 2020-11-17
IL248924B (en) 2020-01-30

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