NZ552751A - Thienopyrimidines useful as aurora kinase inhibitors - Google Patents
Thienopyrimidines useful as aurora kinase inhibitorsInfo
- Publication number
- NZ552751A NZ552751A NZ552751A NZ55275105A NZ552751A NZ 552751 A NZ552751 A NZ 552751A NZ 552751 A NZ552751 A NZ 552751A NZ 55275105 A NZ55275105 A NZ 55275105A NZ 552751 A NZ552751 A NZ 552751A
- Authority
- NZ
- New Zealand
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- compound
- heteroalkyl
- Prior art date
Links
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Classifications
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- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Landscapes
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Applications Claiming Priority (3)
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| US58871804P | 2004-07-16 | 2004-07-16 | |
| US63256804P | 2004-12-01 | 2004-12-01 | |
| PCT/US2005/025340 WO2006036266A1 (en) | 2004-07-16 | 2005-07-15 | Thienopyrimidines useful as aurora kinase inhibitors |
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| NZ552751A true NZ552751A (en) | 2010-11-26 |
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| NZ552751A NZ552751A (en) | 2004-07-16 | 2005-07-15 | Thienopyrimidines useful as aurora kinase inhibitors |
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| Country | Link |
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| US (2) | US7601725B2 (enExample) |
| EP (1) | EP1768984B1 (enExample) |
| JP (1) | JP2008506714A (enExample) |
| KR (1) | KR20070057792A (enExample) |
| AT (1) | ATE485300T1 (enExample) |
| AU (1) | AU2005290226A1 (enExample) |
| BR (1) | BRPI0513405A (enExample) |
| CA (1) | CA2573999A1 (enExample) |
| DE (1) | DE602005024274D1 (enExample) |
| IL (1) | IL180722A0 (enExample) |
| MX (1) | MX2007000631A (enExample) |
| NZ (1) | NZ552751A (enExample) |
| SG (1) | SG156650A1 (enExample) |
| WO (1) | WO2006036266A1 (enExample) |
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| EP1781664B1 (en) | 2004-07-30 | 2013-09-04 | MethylGene Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
| MX2007014617A (es) | 2005-05-20 | 2008-02-11 | Methylgene Inc | Inhibidores de senalizacion de receptor de factor de crecimiento endotelial bascular y receptor de factor de crecimiento de hepatocitos. |
| WO2008041053A2 (en) | 2005-05-20 | 2008-04-10 | Methylgene, Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| WO2007107469A1 (en) * | 2006-03-20 | 2007-09-27 | F. Hoffmann-La Roche Ag | Methods of inhibiting btk and syk protein kinases |
| JP2010505962A (ja) | 2006-10-09 | 2010-02-25 | 武田薬品工業株式会社 | キナーゼ阻害剤 |
| EP2167497A2 (en) * | 2007-06-29 | 2010-03-31 | Sunesis Pharmaceuticals, Inc. | Heterocyclic compounds useful as raf kinase inhibitors |
| EP2014663A1 (de) * | 2007-07-12 | 2009-01-14 | Bayer Schering Pharma AG | Thienopyrimidylamine als Modulatoren des EP2-Rezeptors |
| MX2010009729A (es) | 2008-03-05 | 2010-12-21 | Methylgene Inc | Inhibidores de actividad de proteina tirosina quinasa. |
| JP5498025B2 (ja) * | 2008-03-13 | 2014-05-21 | 公益財団法人相模中央化学研究所 | 新規なチアゾール誘導体固定化マトリックス、及びその製造方法 |
| JP5455380B2 (ja) * | 2008-03-12 | 2014-03-26 | 公益財団法人相模中央化学研究所 | 新規なチアゾール誘導体、及びその製造方法 |
| WO2009113637A1 (ja) * | 2008-03-12 | 2009-09-17 | 東ソー株式会社 | 新規なチアゾール誘導体、チアゾール誘導体固定化マトリックス、及びそれらの製造方法 |
| EP2265618A2 (en) * | 2008-03-14 | 2010-12-29 | Sunesis Pharmaceuticals, Inc. | Aurora kinase inhibitors |
| EP2257637B1 (en) * | 2008-03-25 | 2015-09-23 | Sunesis Pharmaceuticals, Inc. | Methods of chemotype evolution |
| AU2009241469B2 (en) | 2008-04-30 | 2015-05-07 | National Health Research Institutes | Fused bicyclic pyrimidine compounds as Aurora kinase inhibitors |
| AR073739A1 (es) * | 2008-09-10 | 2010-12-01 | Kalypsys Inc | Aminopirimidinas como inhibidores de los receptores de histamina |
| US9006252B2 (en) | 2008-09-26 | 2015-04-14 | National Health Research Institutes | Fused multicyclic compounds as protein kinase inhibitors |
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2005
- 2005-07-15 DE DE602005024274T patent/DE602005024274D1/de not_active Expired - Lifetime
- 2005-07-15 JP JP2007521708A patent/JP2008506714A/ja active Pending
- 2005-07-15 SG SG200906907-1A patent/SG156650A1/en unknown
- 2005-07-15 KR KR1020077003002A patent/KR20070057792A/ko not_active Ceased
- 2005-07-15 AU AU2005290226A patent/AU2005290226A1/en not_active Abandoned
- 2005-07-15 EP EP05772519A patent/EP1768984B1/en not_active Expired - Lifetime
- 2005-07-15 MX MX2007000631A patent/MX2007000631A/es not_active Application Discontinuation
- 2005-07-15 WO PCT/US2005/025340 patent/WO2006036266A1/en not_active Ceased
- 2005-07-15 US US11/182,215 patent/US7601725B2/en not_active Expired - Fee Related
- 2005-07-15 AT AT05772519T patent/ATE485300T1/de not_active IP Right Cessation
- 2005-07-15 BR BRPI0513405-6A patent/BRPI0513405A/pt not_active IP Right Cessation
- 2005-07-15 NZ NZ552751A patent/NZ552751A/en not_active IP Right Cessation
- 2005-07-15 CA CA002573999A patent/CA2573999A1/en not_active Abandoned
-
2007
- 2007-01-16 IL IL180722A patent/IL180722A0/en unknown
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2009
- 2009-10-08 US US12/575,560 patent/US20100179123A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1768984A1 (en) | 2007-04-04 |
| MX2007000631A (es) | 2007-03-30 |
| US20060035908A1 (en) | 2006-02-16 |
| BRPI0513405A (pt) | 2008-05-06 |
| IL180722A0 (en) | 2007-06-03 |
| WO2006036266A1 (en) | 2006-04-06 |
| DE602005024274D1 (de) | 2010-12-02 |
| ATE485300T1 (de) | 2010-11-15 |
| AU2005290226A1 (en) | 2006-04-06 |
| KR20070057792A (ko) | 2007-06-07 |
| CA2573999A1 (en) | 2006-04-06 |
| EP1768984B1 (en) | 2010-10-20 |
| US7601725B2 (en) | 2009-10-13 |
| SG156650A1 (en) | 2009-11-26 |
| JP2008506714A (ja) | 2008-03-06 |
| US20100179123A1 (en) | 2010-07-15 |
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| LAPS | Patent lapsed |