NZ519285A - Method for producing 4-(heteroaryl-methyl)-1(2H)-phthalazinones - Google Patents

Method for producing 4-(heteroaryl-methyl)-1(2H)-phthalazinones

Info

Publication number
NZ519285A
NZ519285A NZ519285A NZ51928500A NZ519285A NZ 519285 A NZ519285 A NZ 519285A NZ 519285 A NZ519285 A NZ 519285A NZ 51928500 A NZ51928500 A NZ 51928500A NZ 519285 A NZ519285 A NZ 519285A
Authority
NZ
New Zealand
Prior art keywords
general formula
phthalazinones
heteroaryl
methyl
pyrazine
Prior art date
Application number
NZ519285A
Other languages
English (en)
Inventor
Orlin Petrov
Tamas Heiner
Harribert Neh
Martin Krueger
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NZ519285A publication Critical patent/NZ519285A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
NZ519285A 1999-12-23 2000-12-20 Method for producing 4-(heteroaryl-methyl)-1(2H)-phthalazinones NZ519285A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19963607A DE19963607B4 (de) 1999-12-23 1999-12-23 Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
PCT/EP2000/013027 WO2001047912A1 (de) 1999-12-23 2000-12-20 Verfahren zur herstellung von 4-(heteroaryl-methyl)-halogen-1(2h)-phthalazinonen

Publications (1)

Publication Number Publication Date
NZ519285A true NZ519285A (en) 2004-12-24

Family

ID=7934888

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ519285A NZ519285A (en) 1999-12-23 2000-12-20 Method for producing 4-(heteroaryl-methyl)-1(2H)-phthalazinones

Country Status (31)

Country Link
US (1) US6891041B2 (enExample)
EP (1) EP1242405B1 (enExample)
JP (1) JP2003529555A (enExample)
KR (1) KR100654265B1 (enExample)
CN (1) CN1221545C (enExample)
AT (1) ATE273972T1 (enExample)
AU (1) AU772981B2 (enExample)
BG (1) BG65387B1 (enExample)
BR (1) BR0016634A (enExample)
CA (1) CA2395407C (enExample)
CZ (1) CZ20022146A3 (enExample)
DE (2) DE19963607B4 (enExample)
DK (1) DK1242405T3 (enExample)
EE (1) EE04940B1 (enExample)
ES (1) ES2223626T3 (enExample)
HR (1) HRP20020605B1 (enExample)
HU (1) HUP0300992A3 (enExample)
IL (2) IL150017A0 (enExample)
MX (1) MXPA02006224A (enExample)
NO (1) NO321357B1 (enExample)
NZ (1) NZ519285A (enExample)
PL (1) PL200714B1 (enExample)
PT (1) PT1242405E (enExample)
RO (1) RO121211B1 (enExample)
RS (1) RS50458B (enExample)
RU (1) RU2250900C2 (enExample)
SI (1) SI1242405T1 (enExample)
SK (1) SK285522B6 (enExample)
UA (1) UA72021C2 (enExample)
WO (1) WO2001047912A1 (enExample)
ZA (1) ZA200205853B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
US7151102B2 (en) * 2000-10-30 2006-12-19 Kudos Pharmaceuticals Limited Phthalazinone derivatives
GB0419072D0 (en) * 2004-08-26 2004-09-29 Kudos Pharm Ltd Phthalazinone derivatives
TWI404716B (zh) * 2006-10-17 2013-08-11 Kudos Pharm Ltd 酞嗪酮（ｐｈｔｈａｌａｚｉｎｏｎｅ）衍生物
KR101598231B1 (ko) * 2007-10-17 2016-02-26 쿠도스 파마슈티칼스 리미티드 4-[3-(4-시클로프로판카르보닐-피페라진-1-카르보닐)-4-플루오로-벤질]-2ｈ-프탈라진-1-온
CA2737400C (en) * 2008-10-07 2016-11-22 Astrazeneca Uk Limited Pharmaceutical formulation 514
JP6545148B2 (ja) 2013-03-13 2019-07-17 フラットリー ディスカバリー ラブ，エルエルシー ピリダジノン化合物及び嚢胞性線維症の治療のための方法
WO2016146303A1 (en) * 2015-03-19 2016-09-22 Clariant International Ltd Biodegradable sugar-amide-surfactants for enhanced oil recovery

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE567431A (enExample) * 1957-05-07
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
EP0634404A1 (en) * 1993-07-13 1995-01-18 Rhone Poulenc Agriculture Ltd. Phtalazin derivatives and their use as pesticides
JP3919835B2 (ja) * 1994-08-09 2007-05-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 縮合ピリダジン系化合物
NZ290952A (en) * 1994-08-09 1998-05-27 Eisai Co Ltd Phthalazine derivatives optionally substituted in position-1 by (generally benzyl) amino groups
RU2128175C1 (ru) * 1994-08-09 1999-03-27 Эйсай Ко., Лтд. Конденсированный пиридазин или его фармакологически приемлемая соль, средство, проявляющее ингибирующую активность в отношении циклической гмф- фосфодиэстеразы
CA2275686C (en) * 1996-12-18 2006-10-17 Neurogen Corporation Isoquinolinamine and phthalazinamine derivatives which interact with crf receptors
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI981671A1 (it) * 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodisterasi 4
ITMI981670A1 (it) * 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI20000261A1 (it) * 2000-02-16 2001-08-16 Zambon Group Processo per la preparazione di piridiniliden-ftalidi

Also Published As

Publication number Publication date
DK1242405T3 (da) 2004-11-01
DE19963607B4 (de) 2005-12-15
RS50458B (sr) 2010-03-02
DE50007520D1 (de) 2004-09-23
US20040192695A1 (en) 2004-09-30
EE04940B1 (et) 2007-12-17
PT1242405E (pt) 2004-11-30
HK1055296A1 (en) 2004-01-02
HRP20020605B1 (en) 2007-06-30
EE200200307A (et) 2003-06-16
BG106843A (en) 2003-02-28
YU47302A (sh) 2005-06-10
MXPA02006224A (es) 2002-12-05
CA2395407C (en) 2009-04-28
NO20023014D0 (no) 2002-06-21
PL200714B1 (pl) 2009-01-30
CN1413203A (zh) 2003-04-23
HUP0300992A3 (en) 2005-11-28
EP1242405A1 (de) 2002-09-25
KR100654265B1 (ko) 2006-12-07
JP2003529555A (ja) 2003-10-07
NO321357B1 (no) 2006-05-02
ES2223626T3 (es) 2005-03-01
IL150017A0 (en) 2002-12-01
KR20020062363A (ko) 2002-07-25
ZA200205853B (en) 2004-02-18
CA2395407A1 (en) 2001-07-05
SI1242405T1 (en) 2005-02-28
EP1242405B1 (de) 2004-08-18
BG65387B1 (bg) 2008-05-30
US6891041B2 (en) 2005-05-10
PL355525A1 (en) 2004-05-04
IL150017A (en) 2006-12-31
RU2002119559A (ru) 2004-01-10
AU772981B2 (en) 2004-05-13
SK8922002A3 (en) 2002-11-06
HRP20020605A2 (en) 2004-12-31
CN1221545C (zh) 2005-10-05
CZ20022146A3 (cs) 2002-09-11
AU2012201A (en) 2001-07-09
ATE273972T1 (de) 2004-09-15
DE19963607A1 (de) 2001-07-12
UA72021C2 (en) 2005-01-17
RU2250900C2 (ru) 2005-04-27
BR0016634A (pt) 2002-10-15
HUP0300992A2 (hu) 2003-08-28
NO20023014L (no) 2002-06-21
SK285522B6 (sk) 2007-03-01
WO2001047912A1 (de) 2001-07-05
RO121211B1 (ro) 2007-01-30

Similar Documents

Publication Publication Date Title
EP1445323A4 (en) PROCESS FOR THE PREPARATION OF GLUTAMINE ACID DERIVATIVES
NZ519285A (en) Method for producing 4-(heteroaryl-methyl)-1(2H)-phthalazinones
IL165503A0 (en) Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and a carboxylic acid in the presence of a sulfonyl chloride and pyridine
TN2009000080A1 (en) Process for preparing n-alkyl naltrexone halides
UA101712C2 (ru) Способ производства производных замещенной метоксиметилпиридин-2,3-дикарбоновой кислоты
MX2009008449A (es) Procedimiento para preparar 2,6-dicloro-4-(trifluorometil)-fenilhi dracina usando mezclas de dicloro-fluoro-trifluorometilbencenos.
WO2003093396A3 (en) Integrated process for preparing fischer-tropsch products and acetic acid from synthesis gas
RU2006130368A (ru) Способ поризводства 2,3-дихлорпиридина
NO20025379D0 (no) FremgangsmÕte for fremstilling av metallformat og maursyreblandinger
JP2005097116A (ja) キノリンカルボン酸誘導体アルカリ金属塩及びこれを用いたキノリンカルボン酸誘導体の精製法
CN101516817A (zh) 制备三氟乙氧基甲苯的方法
JP2012508709A (ja) ２−［（１−シアノプロピル）カルバモイル］−５−クロロメチルニコチン酸及びイミダゾリノン系除草剤の製造におけるその使用
CN107935908A (zh) 一种尼达尼布（nintedanib）的制备方法及其中间体
CN102812009A (zh) 用于合成5-氨基,1-苯基,3-氰基,4-三氟甲基亚磺酰基吡唑的方法
AU9711798A (en) A method of producing aminocyanoacetamide
HU229881B1 (en) Process for the manufacture of substituted triazolinones
JP5364327B2 (ja) ハロピラジンカルボキサミド化合物の製造方法
JP2006008686A (ja) イミキモドの製造方法
CN102649777B (zh) 一种制备1-芳基-3-羧基-5-吡唑啉酮类化合物的方法
TH62498A (th) การเตรียมแอซิดฟอร์เมต
JP2007001882A (ja) ２−クロロ−イソニコチン酸の製造方法
JPH11171872A (ja) カルボキシベンゾトリアゾールの製造方法

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)