NZ500664A - Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose) - Google Patents

Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose)

Info

Publication number
NZ500664A
NZ500664A NZ500664A NZ50066498A NZ500664A NZ 500664 A NZ500664 A NZ 500664A NZ 500664 A NZ500664 A NZ 500664A NZ 50066498 A NZ50066498 A NZ 50066498A NZ 500664 A NZ500664 A NZ 500664A
Authority
NZ
New Zealand
Prior art keywords
granulating
calcium carbonate
microcrystalline cellulose
tricalcium phosphate
bulking agent
Prior art date
Application number
NZ500664A
Other languages
English (en)
Inventor
Andrew Day
Huw Lyn Jones
Carl Simon Smith
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of NZ500664A publication Critical patent/NZ500664A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ500664A 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose) NZ500664A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710521.7A GB9710521D0 (en) 1997-05-22 1997-05-22 Process
PCT/EP1998/003167 WO1998052539A1 (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges

Publications (1)

Publication Number Publication Date
NZ500664A true NZ500664A (en) 2001-01-26

Family

ID=10812840

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ500664A NZ500664A (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges by granulating flubiprofen with a bulking agent (selected from calcium carbonate, tricalcium phosphate or microcrystalline cellulose)

Country Status (31)

Country Link
US (1) US6194003B1 (cg-RX-API-DMAC7.html)
EP (1) EP0983059B1 (cg-RX-API-DMAC7.html)
JP (1) JP2001527567A (cg-RX-API-DMAC7.html)
KR (1) KR20010012739A (cg-RX-API-DMAC7.html)
CN (1) CN1154480C (cg-RX-API-DMAC7.html)
AR (1) AR015812A1 (cg-RX-API-DMAC7.html)
AT (1) ATE245021T1 (cg-RX-API-DMAC7.html)
AU (1) AU725760B2 (cg-RX-API-DMAC7.html)
BG (1) BG103881A (cg-RX-API-DMAC7.html)
BR (1) BR9809651A (cg-RX-API-DMAC7.html)
CA (1) CA2290830C (cg-RX-API-DMAC7.html)
CZ (1) CZ290816B6 (cg-RX-API-DMAC7.html)
DE (1) DE69816440T2 (cg-RX-API-DMAC7.html)
DK (1) DK0983059T3 (cg-RX-API-DMAC7.html)
ES (1) ES2202871T3 (cg-RX-API-DMAC7.html)
GB (1) GB9710521D0 (cg-RX-API-DMAC7.html)
HU (1) HU224954B1 (cg-RX-API-DMAC7.html)
ID (1) ID22949A (cg-RX-API-DMAC7.html)
IL (1) IL132999A0 (cg-RX-API-DMAC7.html)
IN (1) IN187837B (cg-RX-API-DMAC7.html)
MY (1) MY118410A (cg-RX-API-DMAC7.html)
NO (1) NO995681D0 (cg-RX-API-DMAC7.html)
NZ (1) NZ500664A (cg-RX-API-DMAC7.html)
PL (1) PL190947B1 (cg-RX-API-DMAC7.html)
PT (1) PT983059E (cg-RX-API-DMAC7.html)
RU (1) RU2203046C2 (cg-RX-API-DMAC7.html)
SK (1) SK283701B6 (cg-RX-API-DMAC7.html)
TR (1) TR199902725T2 (cg-RX-API-DMAC7.html)
UA (1) UA53714C2 (cg-RX-API-DMAC7.html)
WO (1) WO1998052539A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA984260B (cg-RX-API-DMAC7.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ300558B6 (cs) 1999-12-09 2009-06-17 Reckitt Benckiser Healthcare (Uk) Limited Tabletová kompozice nesteroidního protizánetlivého léciva a zpusob její prípravy
AU2001257022B2 (en) * 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
JP2007528857A (ja) * 2003-07-11 2007-10-18 ミリアド ジェネティクス， インコーポレイテッド アルツハイマー病の処置のための薬学的方法、投与レジメンおよび投薬形態
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
MXPA06012165A (es) * 2004-04-29 2007-01-17 Keystone Retaining Wall System Chapas para muros, muros de contencion y similares.
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CN101128186B (zh) 2005-02-03 2013-07-03 奈科明制药有限公司 制备含钙组合物的快速湿聚结方法
GB2423710A (en) * 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
AU2006272760A1 (en) * 2005-07-22 2007-02-01 Myriad Genetics, Inc. High drug load formulations and dosage forms
KR20080034166A (ko) * 2005-11-02 2008-04-18 테이코쿠 팔마 유에스에이, 인코포레이티드 감각기관 수용성 이부프로펜 경구 투약 제형 및 동일물의제조 및 사용 방법
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
EP2170063A1 (en) * 2007-07-23 2010-04-07 Teikoku Pharma USA, Inc. Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
MX344359B (es) * 2008-08-22 2016-12-14 Reckitt Benckiser Healthcare (Uk) Ltd Composición particulada ingerible para el dolor de garganta.
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
IT1406107B1 (it) * 2010-12-13 2014-02-14 Alfa Wassermann Spa Composizioni solide comprendenti antiinfiammatori non steroidei, processi per la loro preparazione e loro uso.
LT3284459T (lt) 2011-04-29 2021-04-12 Moberg Pharma Ab Farmacinės kompozicijos, apimančios vietinį anestetiką, tokį kaip bupivakainas, skirtos vietiniam įvedimui į burną arba gerklę
EP2609911A1 (en) * 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. A novel process for preparing orally disintegrating flurbiprofen formulations
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
WO2017029710A1 (ja) * 2015-08-18 2017-02-23 合同会社Ｐｈａｒｍａ Ｓｅｅｄｓ Ｃｒｅａｔｅ ＮＳＡＩＤｓまたはヘパリン類含有口腔用組成物
WO2020013781A2 (en) * 2018-03-27 2020-01-16 Pisak Mehmet Nevzat Synergistic effect of flurbiprofen and a gastro protective agent for the treatment of pain and inflammation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4666716A (en) * 1984-09-04 1987-05-19 Richardson-Vicks Inc. Antidiarrheal compositions and use thereof
RU2026670C1 (ru) * 1988-10-05 1995-01-20 Дзе Апджон Компани Способ получения тонкодисперсного твердого фармацевтического вещества
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
IT1244698B (it) * 1991-02-01 1994-08-08 Gentili Ist Spa Acidi aril-o arilalchil-acil ammino-alchil-idrossidifosfonici, procedimento per la loro preparazione e loro uso in terapia osteo-articolare e dei tessuti connettori in generale
US5302394A (en) 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment

Also Published As

Publication number Publication date
PL336624A1 (en) 2000-07-03
EP0983059B1 (en) 2003-07-16
HU224954B1 (en) 2006-04-28
PT983059E (pt) 2003-11-28
CA2290830C (en) 2006-07-11
ES2202871T3 (es) 2004-04-01
NO995681L (no) 1999-11-19
CZ290816B6 (cs) 2002-10-16
AR015812A1 (es) 2001-05-30
RU2203046C2 (ru) 2003-04-27
JP2001527567A (ja) 2001-12-25
ID22949A (id) 1999-12-16
BG103881A (bg) 2000-05-31
CN1255848A (zh) 2000-06-07
BR9809651A (pt) 2000-07-11
GB9710521D0 (en) 1997-07-16
CN1154480C (zh) 2004-06-23
IN187837B (cg-RX-API-DMAC7.html) 2002-06-29
SK158899A3 (en) 2000-05-16
ATE245021T1 (de) 2003-08-15
CZ412099A3 (cs) 2000-02-16
MY118410A (en) 2004-10-30
US6194003B1 (en) 2001-02-27
HUP0002121A3 (en) 2001-04-28
NO995681D0 (no) 1999-11-19
HUP0002121A2 (hu) 2000-12-28
DK0983059T3 (da) 2003-11-03
ZA984260B (en) 1999-02-20
EP0983059A1 (en) 2000-03-08
DE69816440T2 (de) 2004-05-13
TR199902725T2 (xx) 2000-02-21
AU7916598A (en) 1998-12-11
AU725760B2 (en) 2000-10-19
IL132999A0 (en) 2001-03-19
PL190947B1 (pl) 2006-02-28
CA2290830A1 (en) 1998-11-26
KR20010012739A (ko) 2001-02-26
DE69816440D1 (de) 2003-08-21
UA53714C2 (uk) 2003-02-17
WO1998052539A1 (en) 1998-11-26
SK283701B6 (sk) 2003-12-02

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Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): RECKITT BENCKISER HEALTHCARE (UK) LIMITED; BOOTS HEALTHCARE INTERNATIONAL LIMITED

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): RECKITT BENCKISER HEALTHCARE (UK) LIMITED; RECKITT BENCKISER HEALTHCARE (UK) LIMITED

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): RECKITT BENCKISER HEALTHCARE (UK) LIMITED; THE BOOTS COMPANY PLC

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED, GB

Free format text: OLD OWNER(S): BOOTS HEALTHCARE INTERNATIONAL LIMITED

RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired