US6582959B2
(en)
|
1991-03-29 |
2003-06-24 |
Genentech, Inc. |
Antibodies to vascular endothelial cell growth factor
|
US8143283B1
(en)
*
|
1993-03-01 |
2012-03-27 |
The Children's Medical Center Corporation |
Methods for treating blood-born tumors with thalidomide
|
US5629327A
(en)
*
|
1993-03-01 |
1997-05-13 |
Childrens Hospital Medical Center Corp. |
Methods and compositions for inhibition of angiogenesis
|
US6114355A
(en)
*
|
1993-03-01 |
2000-09-05 |
D'amato; Robert |
Methods and compositions for inhibition of angiogenesis
|
US6228879B1
(en)
|
1997-10-16 |
2001-05-08 |
The Children's Medical Center |
Methods and compositions for inhibition of angiogenesis
|
US20040248799A1
(en)
*
|
1993-05-27 |
2004-12-09 |
Holaday John W. |
Compositions and methods for treating cancer and hyperproliferative disorders
|
US6805865B1
(en)
|
1993-05-27 |
2004-10-19 |
Entremed, Inc. |
Compositions and methods for treating cancer and hyperproliferative disorders
|
DE4422237A1
(de)
|
1994-06-24 |
1996-01-04 |
Gruenenthal Gmbh |
Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe
|
US6429221B1
(en)
*
|
1994-12-30 |
2002-08-06 |
Celgene Corporation |
Substituted imides
|
US6358735B1
(en)
|
1995-06-30 |
2002-03-19 |
University Of Kansas Medical Center |
Method for inhibiting angiogenesis and tumors with the isolated NC1 α3 chain monomer of type IV collagen
|
US6440729B1
(en)
|
1995-06-30 |
2002-08-27 |
University Of Kansas Medical Center |
Treating angiogenesis-mediated diseases with the α2 monomer of type IV collagen
|
US6518281B2
(en)
*
|
1995-08-29 |
2003-02-11 |
Celgene Corporation |
Immunotherapeutic agents
|
US6346510B1
(en)
|
1995-10-23 |
2002-02-12 |
The Children's Medical Center Corporation |
Therapeutic antiangiogenic endostatin compositions
|
JP3263598B2
(ja)
*
|
1995-11-01 |
2002-03-04 |
有限会社ドット |
経鼻吸収用生理活性ペプチド組成物
|
EP2177517B1
(en)
*
|
1996-07-24 |
2011-10-26 |
Celgene Corporation |
Amino substituted 2-(2,6-dioxopiperidin-3-yl)-phthalimide for reducing TNF alpha levels
|
DE122007000079I2
(de)
*
|
1996-07-24 |
2010-08-12 |
Celgene Corp |
Substituierte 2-(2,6-dioxopiperidin-3-yl)-phthalimide und -1-oxoisoindoline und verfahren zur reduzierung des tnf-alpha-spiegels
|
US5635517B1
(en)
*
|
1996-07-24 |
1999-06-29 |
Celgene Corp |
Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
|
US5798368A
(en)
*
|
1996-08-22 |
1998-08-25 |
Celgene Corporation |
Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNFα levels
|
US6281230B1
(en)
*
|
1996-07-24 |
2001-08-28 |
Celgene Corporation |
Isoindolines, method of use, and pharmaceutical compositions
|
HU228769B1
(en)
*
|
1996-07-24 |
2013-05-28 |
Celgene Corp |
Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
|
US5955496A
(en)
*
|
1996-08-13 |
1999-09-21 |
The Regents Of The University Of California |
Dihydroxy-oxy-eicosadienoates
|
ATE305301T1
(de)
*
|
1996-11-05 |
2005-10-15 |
Childrens Medical Center |
Mittel zur hemmung von angiogenese enthaltend thalodomid und einen nsaid
|
US6028060A
(en)
|
1997-01-29 |
2000-02-22 |
Vanderbilt University |
Treatment of chronic inflammatory diseases with CM101/GBS toxin
|
US5858991A
(en)
*
|
1997-01-29 |
1999-01-12 |
Vanderbilt University |
Facilitation of wound healing with CM101/GBS toxin
|
US6670337B1
(en)
|
1998-01-29 |
2003-12-30 |
Yeda Reaearch And Development Co., Ltd. |
Facilitation of wound healing with CM101/GBS toxin
|
US5981508A
(en)
*
|
1997-01-29 |
1999-11-09 |
Vanderbilt University |
Facilitation of repair of neural injury with CM101/GBS toxin
|
US6593291B1
(en)
|
1997-02-06 |
2003-07-15 |
Entremed, Inc. |
Compositions and methods of use of ligands that bind components of the blood coagulation/clotting pathway for the treatment of cancer and angiogenic-based disease
|
US5994388A
(en)
*
|
1997-03-18 |
1999-11-30 |
The Children's Medical Center Corporation |
Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis
|
US6265388B1
(en)
|
1997-03-21 |
2001-07-24 |
President And Fellows Of Harvard College |
Antisense inhibition of angiogenin expression
|
US6174695B1
(en)
|
1997-08-12 |
2001-01-16 |
The Regents Of The University Of California |
Epoxide hydrolase inhibitor methods
|
AU8918898A
(en)
|
1997-08-25 |
1999-03-16 |
Harold Brem |
Prevention of adhesions and excessive scar formation using angiogenesis inhibi tors
|
ATE233753T1
(de)
*
|
1997-11-18 |
2003-03-15 |
Celgene Corp |
Substituierte 2-(2,6-dioxo-3-fluoropiperidin-3- yl)-isoindoline und ihre verwendung zur verminderung des tnfa spiegels
|
US5955476A
(en)
*
|
1997-11-18 |
1999-09-21 |
Celgene Corporation |
Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
|
US20010006973A1
(en)
*
|
1998-03-16 |
2001-07-05 |
Hon-Wah Man |
1-oxo- and 1,3-dioxoisoindolines and method of reducing inflammatory cytokine levels
|
EP1083896A4
(en)
|
1998-05-11 |
2002-09-11 |
Endowment For Res In Human Bio |
USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES
|
WO1999058096A2
(en)
|
1998-05-11 |
1999-11-18 |
Entremed, Inc. |
Analogs of 2-phthalimidinoglutaric acid and their use as inhibitors of angiogenesis
|
US6673828B1
(en)
*
|
1998-05-11 |
2004-01-06 |
Children's Medical Center Corporation |
Analogs of 2-Phthalimidinoglutaric acid
|
US20050265996A1
(en)
*
|
2004-04-30 |
2005-12-01 |
Biopheresis Technologies, Inc. |
Method and system to remove soluble TNFR1, TNFR2, and IL2 in patients
|
US6620382B1
(en)
|
1998-05-22 |
2003-09-16 |
Biopheresis Technologies, Llc. |
Method and compositions for treatment of cancers
|
US8197430B1
(en)
*
|
1998-05-22 |
2012-06-12 |
Biopheresis Technologies, Inc. |
Method and system to remove cytokine inhibitor in patients
|
US8609614B2
(en)
|
1998-07-22 |
2013-12-17 |
Vanderbilt University |
GBS toxin receptor compositions and methods of use
|
US6576613B1
(en)
*
|
1998-07-24 |
2003-06-10 |
Corvas International, Inc. |
Title inhibitors of urokinase
|
US6703050B1
(en)
*
|
1998-09-04 |
2004-03-09 |
The Regents Of The University Of Michigan |
Methods and compositions for the prevention or treatment of cancer
|
US6537554B1
(en)
|
1998-09-10 |
2003-03-25 |
Curagen Corporation |
Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
|
AU5991699A
(en)
|
1998-09-21 |
2000-04-10 |
Biochem Pharma Inc. |
Quinolizinones as integrin inhibitors
|
US6231889B1
(en)
*
|
1998-09-21 |
2001-05-15 |
Chronorx, Llc |
Unit dosage forms for the treatment of herpes simplex
|
US6596690B2
(en)
|
1998-10-06 |
2003-07-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vasostatin as marrow protectant
|
FR2784580B1
(fr)
|
1998-10-16 |
2004-06-25 |
Biosepra Inc |
Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US7238711B1
(en)
|
1999-03-17 |
2007-07-03 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
AU2612100A
(en)
*
|
1999-01-13 |
2000-08-01 |
Rockefeller University, The |
Methods of promoting or enhancing interleukin-12 production through administration of thalidomide
|
AU771015B2
(en)
|
1999-03-18 |
2004-03-11 |
Celgene Corporation |
Substituted 1-oxo- and 1,3-dioxoisoindolines and their use in pharmaceutical compositions for reducing inflammatory cytokine levels
|
SI1040838T1
(en)
|
1999-03-31 |
2003-08-31 |
Gruenenthal Gmbh |
Stable aqueous solution of 3-(1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
US7629360B2
(en)
*
|
1999-05-07 |
2009-12-08 |
Celgene Corporation |
Methods for the treatment of cachexia and graft v. host disease
|
US6468990B1
(en)
*
|
1999-05-17 |
2002-10-22 |
Queen's University At Kingston |
Method of inhibiting binding of nerve growth factor to p75 NTR receptor
|
US6673843B2
(en)
|
1999-06-30 |
2004-01-06 |
Emory University |
Curcumin and curcuminoid inhibition of angiogenesis
|
US6916843B1
(en)
*
|
1999-08-11 |
2005-07-12 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids
|
US7087592B1
(en)
|
1999-08-23 |
2006-08-08 |
Entre Med, Inc. |
Compositions comprising purified 2-methoxyestradiol and methods of producing same
|
US20040214783A1
(en)
|
2002-05-08 |
2004-10-28 |
Terman David S. |
Compositions and methods for treatment of neoplastic disease
|
EP2087907B1
(en)
|
1999-11-10 |
2014-09-24 |
Innatus Corporation |
Method and system to remove cytokine inhibitor in patients
|
US6204270B1
(en)
*
|
1999-11-12 |
2001-03-20 |
Eyal S. Ron |
Ophthalmic and mucosal preparations
|
DE60035218D1
(de)
|
1999-11-18 |
2007-07-26 |
Dendreon Corp |
Nukleinsäuren, welche für endotheliasen kodieren, endotheliasen, sowie deren verwendung
|
US6379708B1
(en)
*
|
1999-11-20 |
2002-04-30 |
Cytologic, Llc |
Method for enhancing immune responses in mammals
|
WO2001041755A2
(en)
*
|
1999-12-02 |
2001-06-14 |
The Regents Of The University Of Michigan |
Topical compositions comprising thalidomide for the treatment of inflammatory diseases
|
US7182953B2
(en)
*
|
1999-12-15 |
2007-02-27 |
Celgene Corporation |
Methods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders
|
US6699899B1
(en)
*
|
1999-12-21 |
2004-03-02 |
Celgene Corporation |
Substituted acylhydroxamic acids and method of reducing TNFα levels
|
US7700341B2
(en)
*
|
2000-02-03 |
2010-04-20 |
Dendreon Corporation |
Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
|
CN1121218C
(zh)
*
|
2000-03-08 |
2003-09-17 |
台湾东洋药品工业股份有限公司 |
酞胺哌啶酮在治疗肝细胞癌的药物组合物中的应用
|
US8697137B2
(en)
|
2000-03-24 |
2014-04-15 |
Biosphere Medical, Inc. |
Methods of using microspheres for active embolization
|
US20030212022A1
(en)
*
|
2001-03-23 |
2003-11-13 |
Jean-Marie Vogel |
Compositions and methods for gene therapy
|
JP2003528918A
(ja)
*
|
2000-03-31 |
2003-09-30 |
セルジーン コーポレイション |
シクロオキシゲナーゼ−2活性の阻害
|
AU6147301A
(en)
|
2000-05-15 |
2001-11-26 |
Celgene Corp |
Compositions and methods for the treatment of colorectal cancer
|
EP1307197B1
(en)
|
2000-05-15 |
2006-04-05 |
Celgene Corporation |
Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide
|
US20030104573A1
(en)
*
|
2000-09-11 |
2003-06-05 |
Shimkets Richard A. |
Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
|
US6458810B1
(en)
|
2000-11-14 |
2002-10-01 |
George Muller |
Pharmaceutically active isoindoline derivatives
|
AU2002253795B2
(en)
*
|
2000-11-30 |
2007-02-01 |
The Children's Medical Center Corporation |
Synthesis of 4-Amino-Thalidomide enantiomers
|
US20040121945A1
(en)
*
|
2000-12-15 |
2004-06-24 |
Hong Liang |
Compositions and methods for inhibiting endothelial cell proliferation
|
EP1226824A1
(en)
*
|
2001-01-24 |
2002-07-31 |
TTY Biopharm Company Limited |
Use of thalidomide for the treatment of hepatocellular carcinoma
|
US6632835B2
(en)
|
2001-02-22 |
2003-10-14 |
Nanodesign Inc. |
Dibenzo[c]chromen-6-one derivatives as anti-cancer agents
|
WO2002068414A2
(en)
*
|
2001-02-27 |
2002-09-06 |
The Governement Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Analogs of thalidomide as potential angiogenesis inhibitors
|
EP1389103A4
(en)
*
|
2001-04-23 |
2005-09-14 |
Univ Virginia |
SYNTHESIS AND EVALUATION OF NEW MIMETIC PHTHALIMIDE SUBSTANCES AS ANTIANGIOGENESIS AGENTS
|
MXPA04000204A
(es)
*
|
2001-07-27 |
2004-03-18 |
Univ Kansas Medical Center |
Estructura cristalizada de colageno tipo iv del hexamero de dominio nc1.
|
NZ531294A
(en)
*
|
2001-08-06 |
2005-11-25 |
Childrens Medical Center |
Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs
|
GB0125659D0
(en)
*
|
2001-10-25 |
2001-12-19 |
Ssl Int Plc |
Spermicides
|
US20030134794A1
(en)
*
|
2001-11-20 |
2003-07-17 |
Madison Edwin L. |
Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon
|
US20030139469A1
(en)
*
|
2002-01-23 |
2003-07-24 |
The Regents Of The University Of California |
Use of inhibitors of soluble epoxide hydrolase to inhibit vascular smooth muscle cell proliferation
|
US7939497B2
(en)
*
|
2002-03-08 |
2011-05-10 |
Shanghai Institutes For Biological Sciences, Cas |
Detection and modulation of slit and roundabount (robo) mediated angiogenesis and uses thereof
|
EP1572078A4
(en)
*
|
2002-03-08 |
2006-08-09 |
Univ Emory |
NEW CURCUMINOID FACTOR VIIa CONSTRUCTS AS MEANS OF SUPPRESSING TUMOR GROWTH AND ANGIOGENESIS
|
AU2003220685A1
(en)
*
|
2002-04-09 |
2003-10-27 |
Greenville Hospital System |
Metastasis modulating activity of highly sulfated oligosaccharides
|
USRE48890E1
(en)
|
2002-05-17 |
2022-01-11 |
Celgene Corporation |
Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation
|
US7393862B2
(en)
*
|
2002-05-17 |
2008-07-01 |
Celgene Corporation |
Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
|
US20100129363A1
(en)
*
|
2002-05-17 |
2010-05-27 |
Zeldis Jerome B |
Methods and compositions using pde4 inhibitors for the treatment and management of cancers
|
JP2005530780A
(ja)
*
|
2002-05-17 |
2005-10-13 |
セルジーン・コーポレーション |
癌および他の疾患を治療および管理するための選択的サイトカイン阻害薬を用いた方法および組成物
|
US7323479B2
(en)
|
2002-05-17 |
2008-01-29 |
Celgene Corporation |
Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
|
US7968569B2
(en)
|
2002-05-17 |
2011-06-28 |
Celgene Corporation |
Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
ES2521672T3
(es)
|
2002-05-17 |
2014-11-13 |
Celgene Corporation |
Formulaciones farmacéuticas para el tratamiento del cáncer
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
CA2490129A1
(en)
*
|
2002-06-26 |
2004-01-08 |
Entremed, Inc. |
Compositions and methods comprising protein activated receptor antagonists
|
JP4827411B2
(ja)
|
2002-07-15 |
2011-11-30 |
ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム |
陰イオン性リン脂質およびアミノリン脂質に結合する選択された抗体およびデュラマイシンペプチド、ならびにウイルス感染の処置におけるそれらの使用
|
JP2005537282A
(ja)
*
|
2002-07-22 |
2005-12-08 |
ケムジェネックス・ファーマシューティカルズ・リミテッド |
セファロタキシンアルカロイドによる血管新生抑制、並びにその誘導体、組成物、および使用方法
|
US7888389B2
(en)
*
|
2002-07-23 |
2011-02-15 |
The Regents Of The University Of Michigan |
Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies
|
US7189740B2
(en)
*
|
2002-10-15 |
2007-03-13 |
Celgene Corporation |
Methods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes
|
US8404717B2
(en)
*
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes using lenalidomide
|
EP1900369A1
(en)
|
2002-10-15 |
2008-03-19 |
Celgene Corporation |
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes
|
KR20050056247A
(ko)
*
|
2002-10-15 |
2005-06-14 |
셀진 코포레이션 |
골수형성이상증후군의 치료 및 관리를 위한 선택적인사이토킨 저해 약물의 사용 방법 및 이를 포함하는 조성물
|
US11116782B2
(en)
|
2002-10-15 |
2021-09-14 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
US8404716B2
(en)
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
US20050203142A1
(en)
*
|
2002-10-24 |
2005-09-15 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
|
US20040087558A1
(en)
*
|
2002-10-24 |
2004-05-06 |
Zeldis Jerome B. |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
US20040091455A1
(en)
*
|
2002-10-31 |
2004-05-13 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
|
US7776907B2
(en)
*
|
2002-10-31 |
2010-08-17 |
Celgene Corporation |
Methods for the treatment and management of macular degeneration using cyclopropyl-N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide
|
TWI310312B
(en)
*
|
2002-10-31 |
2009-06-01 |
Celgene Corp |
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of macular degeneration
|
ZA200503655B
(en)
|
2002-11-06 |
2006-08-30 |
Celgene Corp |
Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases
|
US8034831B2
(en)
*
|
2002-11-06 |
2011-10-11 |
Celgene Corporation |
Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
|
US7563810B2
(en)
*
|
2002-11-06 |
2009-07-21 |
Celgene Corporation |
Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
|
US20060074100A1
(en)
*
|
2002-11-12 |
2006-04-06 |
Klimko Peter G |
Histone deacetylase inhibitors for the treatment of ocular neovascular or edematous disorders and diseases
|
US9006267B2
(en)
*
|
2002-11-14 |
2015-04-14 |
Celgene Corporation |
Pharmaceutical compositions and dosage forms of thalidomide
|
US7230012B2
(en)
|
2002-11-14 |
2007-06-12 |
Celgene Corporation |
Pharmaceutical compositions and dosage forms of thalidomide
|
US8431396B2
(en)
|
2003-03-21 |
2013-04-30 |
The Cleveland Clinic Foundation |
Anti-angiogenic peptides
|
US7517887B2
(en)
*
|
2003-04-09 |
2009-04-14 |
General Atomics |
Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof
|
US7868011B2
(en)
*
|
2003-04-09 |
2011-01-11 |
General Atomics |
Use of reversible inhibitors of S-adenosyl-L-homocysteine hydrolase for treating lupus
|
US7196093B2
(en)
*
|
2003-04-09 |
2007-03-27 |
General Atomics |
Reversible inhibitors of SAH hydrolase and uses thereof
|
DE10323898A1
(de)
|
2003-05-26 |
2004-12-23 |
Wilex Ag |
Hydroxyamidin- und Hydroxyguanidin-Verbindungen als Urokinase-Hemmstoffe
|
WO2005030120A2
(en)
*
|
2003-05-28 |
2005-04-07 |
Entremed, Inc. |
Antiangiogenic agents
|
WO2005016326A2
(en)
*
|
2003-07-11 |
2005-02-24 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Analogs of thalidomide as potential angiogenesis inhibitors
|
ES2523837T3
(es)
|
2003-07-18 |
2014-12-01 |
Amgen Inc. |
Agentes de unión específica al factor de crecimiento de hepatocitos
|
UA83504C2
(en)
*
|
2003-09-04 |
2008-07-25 |
Селджин Корпорейшн |
Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
|
CN1867331B
(zh)
|
2003-09-17 |
2010-05-26 |
美国政府健康及人类服务部 |
作为TNF-α调节剂的沙利度胺类似物
|
US8952895B2
(en)
|
2011-06-03 |
2015-02-10 |
Apple Inc. |
Motion-based device operations
|
US20080027113A1
(en)
*
|
2003-09-23 |
2008-01-31 |
Zeldis Jerome B |
Methods of Using and Compositions Comprising Immunomodulatory Compounds for Treatment and Management of Macular Degeneration
|
US7612096B2
(en)
*
|
2003-10-23 |
2009-11-03 |
Celgene Corporation |
Methods for treatment, modification and management of radiculopathy using 1-oxo-2-(2,6-dioxopiperidin-3yl)-4-aminoisoindoline
|
WO2005046686A1
(en)
*
|
2003-11-06 |
2005-05-26 |
Celgene Corporation |
Methods and compositions using thalidomide for the treatment and management of cancers and other diseases
|
US20050100529A1
(en)
*
|
2003-11-06 |
2005-05-12 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
|
EA200600921A1
(ru)
*
|
2003-11-06 |
2006-10-27 |
Селджин Корпорейшн |
Способы и композиции с применением талидомида для лечения и менеджмента рака и других заболеваний
|
EP1694328A4
(en)
*
|
2003-12-02 |
2010-02-17 |
Celgene Corp |
METHOD AND COMPOSITIONS FOR THE TREATMENT AND SUPPLY OF HEMOGLOBINOPATHY AND ANEMIA
|
US20050143344A1
(en)
*
|
2003-12-30 |
2005-06-30 |
Zeldis Jerome B. |
Methods and compositions using immunomodulatory compounds for the treatment and management of central nervous system disorders or diseases
|
US7430276B2
(en)
*
|
2004-02-25 |
2008-09-30 |
Nanodynamics-88 |
Low dose X-ray mammography method
|
WO2005089256A2
(en)
*
|
2004-03-12 |
2005-09-29 |
Entremed, Inc. |
Antiangiogenic agents
|
MXPA06010699A
(es)
*
|
2004-03-22 |
2006-12-15 |
Celgene Corp |
Metodos de usos y composiciones que contienen compuestos inmunomoduladores para el tratamiento y manejo de enfermedades o alteraciones de la piel.
|
US20050222209A1
(en)
*
|
2004-04-01 |
2005-10-06 |
Zeldis Jerome B |
Methods and compositions for the treatment, prevention or management of dysfunctional sleep and dysfunctional sleep associated with disease
|
WO2005110408A1
(en)
*
|
2004-04-14 |
2005-11-24 |
Celgene Corporation |
Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes
|
CA2563207A1
(en)
*
|
2004-04-14 |
2005-11-24 |
Celgene Corporation |
Use of selective cytokine inhibitory drugs in myelodysplastic syndromes
|
JP2007533759A
(ja)
*
|
2004-04-23 |
2007-11-22 |
セルジーン・コーポレーション |
肺高血圧症の治療及び管理のためのサリドマイドを含む組成物及びその使用方法
|
JP2007533761A
(ja)
*
|
2004-04-23 |
2007-11-22 |
セルジーン・コーポレーション |
肺高血圧症を治療し管理するための、免疫調節性化合物の使用方法及び免疫調節性化合物を含む組成物
|
US7273890B1
(en)
*
|
2004-06-08 |
2007-09-25 |
Sagittarius Life Science Corp. |
ST104P, an anti-angiogenic agent
|
EP1778652A2
(en)
*
|
2004-08-20 |
2007-05-02 |
EntreMed, Inc. |
Compositions and methods comprising proteinase activated receptor antagonists
|
AU2005282728A1
(en)
*
|
2004-09-03 |
2006-03-16 |
Celgene Corporation |
Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines
|
MX2007005040A
(es)
*
|
2004-10-28 |
2007-06-19 |
Celgene Corp |
Metodos y composiciones usando moduladores de pde4 para el tratamiento y manejo de lesion al sistema nervioso central.
|
AU2005309733A1
(en)
*
|
2004-11-23 |
2006-06-01 |
Celgene Corporation |
Methods and compositions using immunomodulatory compounds for treatment and management of central nervous system injury
|
CN104815331A
(zh)
|
2005-05-09 |
2015-08-05 |
生物领域医疗公司 |
使用微球和非离子型造影剂的组合物和方法
|
US20060270707A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Zeldis Jerome B |
Methods and compositions using 4-[(cyclopropanecarbonylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione for the treatment or prevention of cutaneous lupus
|
US20080167272A1
(en)
*
|
2005-06-16 |
2008-07-10 |
Auckland Uniservices Limited |
Thalidomide metabolites and methods of use
|
SI2380887T1
(sl)
*
|
2005-06-30 |
2013-12-31 |
Celgene Corporation |
Postopki priprave spojin 4-amino-2-/2,6-dioksopiperidin-3-il)izoindolin -1,3-diona
|
US20080279912A1
(en)
*
|
2005-07-12 |
2008-11-13 |
Regents Of The University Of California Office Of Technology Transfer |
Use of Cis-Epoxyeicosatrienoic Acids And Inhibitors of Soluble Epoxide Hydrolase to Alleviate Eye Disorders
|
US20080138295A1
(en)
*
|
2005-09-12 |
2008-06-12 |
Celgene Coporation |
Bechet's disease using cyclopropyl-N-carboxamide
|
US20070065514A1
(en)
*
|
2005-09-22 |
2007-03-22 |
Howell Mark D |
Method for enhancing immune responses in mammals
|
CN1939922B
(zh)
*
|
2005-09-27 |
2010-10-13 |
天津和美生物技术有限公司 |
可抑制细胞释放肿瘤坏死因子的5H-噻吩[3,4-c]吡咯-4,6-二酮衍生物
|
EP1940410A1
(en)
*
|
2005-10-14 |
2008-07-09 |
F.Hoffmann-La Roche Ag |
Regimen of administration for 5-(2-chlorophenyl)-1 ,2-dihydro-7-fluoro-8-methoxy-3-methyl-pyrazolo [3, 4.-b] [1, 4] benzodiazepine
|
US20070155791A1
(en)
*
|
2005-12-29 |
2007-07-05 |
Zeldis Jerome B |
Methods for treating cutaneous lupus using aminoisoindoline compounds
|
ATE520427T1
(de)
*
|
2006-01-30 |
2011-09-15 |
Biosphere Medical Inc |
Poröse intravaskuläre embolisierungsteilchen und verfahren zu deren herstellung
|
EP1986707A2
(en)
|
2006-01-30 |
2008-11-05 |
Surgica Corporation |
Compressible intravascular embolization particles and related methods and delivery systems
|
WO2007109312A2
(en)
*
|
2006-03-20 |
2007-09-27 |
Entremed, Inc. |
Disease modifying anti-arthritic activity of 2-methoxyestradiol
|
US20070226632A1
(en)
*
|
2006-03-21 |
2007-09-27 |
Nokia Corporation |
Method, electronic device and computer program product for enhancing contact list functionality
|
AU2007238785B2
(en)
*
|
2006-04-13 |
2013-02-07 |
Agnieszka Ambrozak |
Tetrahalogenated compounds useful as inhibitors of angiogenesis
|
WO2007136640A2
(en)
*
|
2006-05-16 |
2007-11-29 |
Celgene Corporation |
Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
|
US20080051431A1
(en)
*
|
2006-05-26 |
2008-02-28 |
Dominique Verhelle |
Methods and compositions using immunomodulatory compounds in combination therapy
|
CA2652888A1
(en)
*
|
2006-05-26 |
2007-12-06 |
Celgene Corporation |
Methods and compositions using immunomodulatory compounds in combination therapy
|
WO2008007979A1
(en)
*
|
2006-07-12 |
2008-01-17 |
Auckland Uniservices Limited |
(2,6-dioxo-3-piperinyl)amidobenzoic immunomodulatory and anti-cancer derivatives
|
PE20121506A1
(es)
|
2006-07-14 |
2012-11-26 |
Amgen Inc |
Compuestos triazolopiridinas como inhibidores de c-met
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
WO2008011513A2
(en)
|
2006-07-19 |
2008-01-24 |
The Cleveland Clinic Foundation |
Compounds and methods of modulating angiogenesis
|
CL2007002218A1
(es)
*
|
2006-08-03 |
2008-03-14 |
Celgene Corp Soc Organizada Ba |
Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa.
|
CN101138634A
(zh)
|
2006-09-07 |
2008-03-12 |
于保法 |
用于治疗肿瘤的组合物
|
US20080075690A1
(en)
*
|
2006-09-22 |
2008-03-27 |
Mark Douglas Howell |
Method for enhancing immune responses in mammals
|
US8314087B2
(en)
|
2007-02-16 |
2012-11-20 |
Amgen Inc. |
Nitrogen-containing heterocyclyl ketones and methods of use
|
CN103285015B
(zh)
*
|
2007-04-13 |
2016-04-27 |
化学基因制药公司 |
三尖杉碱口服剂型
|
US7893045B2
(en)
*
|
2007-08-07 |
2011-02-22 |
Celgene Corporation |
Methods for treating lymphomas in certain patient populations and screening patients for said therapy
|
WO2009026303A1
(en)
|
2007-08-21 |
2009-02-26 |
Amgen Inc. |
Human c-fms antigen binding proteins
|
TW200918099A
(en)
|
2007-09-14 |
2009-05-01 |
Nitto Denko Corp |
Drug carriers
|
US11331294B2
(en)
|
2007-09-26 |
2022-05-17 |
Indiana University Research And Technology Corporation |
Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of bladder cancer
|
AU2008304619C1
(en)
*
|
2007-09-26 |
2020-06-04 |
Indiana University Research And Technology Corporation |
Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of cancer and angiogenesis
|
KR101502267B1
(ko)
|
2007-11-09 |
2015-03-18 |
페레그린 파마수티컬즈, 인크 |
항-vegf 항체 조성물 및 방법
|
US20090137631A1
(en)
*
|
2007-11-22 |
2009-05-28 |
National Yang-Ming University |
Methods and pharmaceutical compositions for regulation of g- and/or gc-rich nucleic acid expression
|
AU2009269149B2
(en)
|
2008-06-30 |
2016-03-17 |
Mesoblast, Inc. |
Treatment of eye diseases and excessive neovascularization using a combined therapy
|
AU2009274512A1
(en)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Clip inhibitors and methods of modulating immune function
|
WO2010062678A2
(en)
*
|
2008-10-30 |
2010-06-03 |
David Liu |
Micro-spherical porous biocompatible scaffolds and methods and apparatus for fabricating same
|
WO2010135396A2
(en)
|
2009-05-19 |
2010-11-25 |
Celgene Corporation |
Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione
|
JP5645816B2
(ja)
|
2009-05-25 |
2014-12-24 |
国立大学法人東京工業大学 |
中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物
|
GB0914330D0
(en)
|
2009-08-17 |
2009-09-30 |
Univ Dublin City |
A method of predicting response to thalidomide in multiple myeloma patients
|
WO2011038139A1
(en)
|
2009-09-23 |
2011-03-31 |
Amgen Inc. |
Treatment of ovarian cancer using a specific binding agent of human angiopoietin-2 in combination with a taxane
|
US20140031325A1
(en)
|
2010-12-06 |
2014-01-30 |
Celgene Corporation |
Combination therapy with lenalidomide and a cdk inhibitor for treating multiple myeloma
|
EP2649095B1
(en)
|
2010-12-10 |
2021-10-06 |
Aleksander S. Popel |
Mimetic peptides derived from collagen type iv and their use for treating angiogenesis- and lymphangiogenesis- dependent diseases
|
MY161199A
(en)
|
2011-03-23 |
2017-04-14 |
Amgen Inc |
Fused tricyclic dual inhibitors of cdk 4/6 and flt3
|
WO2012149299A2
(en)
|
2011-04-29 |
2012-11-01 |
Celgene Corporaiton |
Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
|
MX358726B
(es)
|
2011-06-29 |
2018-09-03 |
Amgen Inc |
Biomarcador predictivo de supervivencia en el tratamiento de carcinoma de celulas renales.
|
WO2013025939A2
(en)
|
2011-08-16 |
2013-02-21 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating cancer by inhibiting the urokinase receptor
|
US20130058926A1
(en)
*
|
2011-08-30 |
2013-03-07 |
Shiseido Company, Ltd. |
Method for alleviating and/or preventing skin reddening
|
US8927725B2
(en)
|
2011-12-02 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Thio compounds
|
WO2013126394A1
(en)
|
2012-02-21 |
2013-08-29 |
Celgene Corporation |
Solid forms of 3-(4-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
EP3904875A1
(en)
*
|
2012-06-29 |
2021-11-03 |
Celgene Corporation |
Methods for determining drug efficacy using ikzf3 (aiolos)
|
US9587281B2
(en)
|
2012-08-14 |
2017-03-07 |
Celgene Corporation |
Cereblon isoforms and their use as biomarkers for therapeutic treatment
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
CA2900529A1
(en)
|
2013-02-08 |
2014-08-14 |
Institute For Myeloma & Bone Cancer Research |
Improved diagnostic, prognostic, and monitoring methods for multiple myeloma, chronic lymphocytic leukemia, and b-cell non-hodgkin lymphoma
|
WO2014125477A1
(en)
|
2013-02-13 |
2014-08-21 |
Cartiheal (2009) Ltd |
Solid substrates for mitigating or preventing cell and tissue adhesion and vascularization
|
US10238690B2
(en)
|
2013-03-15 |
2019-03-26 |
Celgene Corporation |
Modified T lymphocytes comprising an inducible caspase and methods of apoptosis
|
EP2815749A1
(en)
|
2013-06-20 |
2014-12-24 |
IP Gesellschaft für Management mbH |
Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
|
US8906951B1
(en)
|
2013-06-24 |
2014-12-09 |
Tigercat Pharma, Inc. |
Use of NK-1 receptor antagonists in pruritus
|
US9198898B2
(en)
|
2013-06-24 |
2015-12-01 |
Tigercat Pharma, Inc. |
Use of NK-1 receptor antagonists in pruritus
|
AU2015210999A1
(en)
|
2014-01-29 |
2016-07-21 |
Otsuka Pharmaceutical Co., Ltd. |
Device-based risk management of a therapeutic
|
ES2946179T3
(es)
|
2014-05-28 |
2023-07-13 |
Onco Tracker Inc |
Efectos antineoplásicos de inhibidores de JAK2 en combinación con derivados de talidomida y glucocorticoides
|
WO2015200795A1
(en)
|
2014-06-27 |
2015-12-30 |
Celgene Corporation |
Compositions and methods for inducing conformational changes in cereblon other e3 ubiquitin ligases
|
EP3925609A1
(en)
|
2014-08-22 |
2021-12-22 |
Celgene Corporation |
Methods of treating multiple myeloma with immunomodulatory compounds in combination with antibodies
|
RU2695521C9
(ru)
|
2014-10-30 |
2019-08-19 |
Канпу Биофармасьютикалс, Лтд. |
Производное изоиндолина, промежуточный продукт, способ получения, фармацевтическая композиция и ее применение
|
CN107106531A
(zh)
|
2014-11-26 |
2017-08-29 |
于保法 |
微创精准个体化肿瘤内化学诱导免疫治疗方法半抗原增强的化学免疫治疗
|
US20190004048A1
(en)
|
2015-06-26 |
2019-01-03 |
Amgen Inc. |
Biomarker of Survival in the Treatment of Renal Cell Carcinoma with a VEGFR Inhibitor and an Ang2 Inhibitor
|
SI3313818T1
(sl)
|
2015-06-26 |
2024-03-29 |
Celgene Corporation |
Postopki zdravljenja Kaposijevega sarkoma ali s KSHV povzročenega limfoma, z uporabo imunomodulatornih spojin in uporabe biomarkerjev
|
CA2992557A1
(en)
|
2015-07-24 |
2017-02-02 |
Oncotracker, Inc. |
Gamma secretase modulators for the treatment of immune system dysfunction
|
AU2016330967B2
(en)
|
2015-09-30 |
2021-03-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Thalidomide analogs and methods of use
|
WO2017068412A1
(en)
|
2015-10-21 |
2017-04-27 |
Otsuka Pharmaceutical Co., Ltd. |
Benzolactam compounds as protein kinase inhibitors
|
US10830762B2
(en)
|
2015-12-28 |
2020-11-10 |
Celgene Corporation |
Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
|
ES2898329T3
(es)
|
2016-01-12 |
2022-03-07 |
Oncotracker Inc |
Métodos mejorados para supervisar el estado inmunitario de un sujeto
|
US10870708B2
(en)
*
|
2016-03-31 |
2020-12-22 |
University Of Leicester |
Methods for inhibiting angiogenesis in a subject in need thereof
|
BR112019011025A2
(pt)
|
2016-12-03 |
2019-10-08 |
Juno Therapeutics Inc |
métodos para modulação de células t car
|
ES2961666T3
(es)
|
2016-12-03 |
2024-03-13 |
Juno Therapeutics Inc |
Métodos para determinar la dosificación de células CAR-T
|
LT3558955T
(lt)
|
2016-12-22 |
2021-11-10 |
Amgen Inc. |
Benzizotiazolo, izotiazolo[3,4-b]piridazino ir ftalazino, pirido[2,3-d] piridazino ir pirido[2,3-d]pirimidino dariniai, kaip kras g12c inhibitoriai, skirti plaučių, kasos arba storosios žarnos vėžio gydymui
|
US10786471B2
(en)
|
2017-02-06 |
2020-09-29 |
Massachusetts Institute Of Technology |
Methods and products related to glutaminase inhibitors
|
GB201706327D0
(en)
|
2017-04-20 |
2017-06-07 |
Otsuka Pharma Co Ltd |
A pharmaceutical compound
|
PT3618842T
(pt)
|
2017-05-01 |
2024-01-12 |
Juno Therapeutics Inc |
Combinação de uma terapia celular e de um composto imunomodulador
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
US10093647B1
(en)
|
2017-05-26 |
2018-10-09 |
Celgene Corporation |
Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione dihydrate, compositions and methods of use thereof
|
KR20200054160A
(ko)
|
2017-06-02 |
2020-05-19 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 요법을 사용한 치료를 위한 물품 제조 및 방법
|
US11635435B2
(en)
|
2017-06-13 |
2023-04-25 |
Oncotracker, Inc. |
Diagnostic, prognostic, and monitoring methods for solid tumor cancers
|
CA3067602A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
US10513515B2
(en)
|
2017-08-25 |
2019-12-24 |
Biotheryx, Inc. |
Ether compounds and uses thereof
|
TWI731264B
(zh)
|
2017-09-08 |
2021-06-21 |
美商安進公司 |
Kras g12c抑制劑以及其使用方法
|
US10093649B1
(en)
|
2017-09-22 |
2018-10-09 |
Celgene Corporation |
Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione monohydrate, compositions and methods of use thereof
|
US10093648B1
(en)
|
2017-09-22 |
2018-10-09 |
Celgene Corporation |
Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione hemihydrate, compositions and methods of use thereof
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
BR112020008323A2
(pt)
|
2017-11-01 |
2020-11-03 |
Juno Therapeutics Inc |
anticorpos e receptores de antígenos quiméricos específicos para antígeno de maturação de células b
|
KR20200116081A
(ko)
|
2017-12-01 |
2020-10-08 |
주노 쎄러퓨티크스 인코퍼레이티드 |
유전자 조작된 세포의 투약 및 조절 방법
|
JP2021506260A
(ja)
|
2017-12-15 |
2021-02-22 |
ジュノー セラピューティクス インコーポレイテッド |
抗cct5結合分子およびその使用方法
|
US10537585B2
(en)
|
2017-12-18 |
2020-01-21 |
Dexcel Pharma Technologies Ltd. |
Compositions comprising dexamethasone
|
WO2019210080A1
(en)
*
|
2018-04-25 |
2019-10-31 |
The Regents Of The University Of California |
Methods and compositions for skeletal and neurological disorders
|
WO2019213516A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
MA52496A
(fr)
|
2018-05-04 |
2021-03-10 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
WO2019217691A1
(en)
|
2018-05-10 |
2019-11-14 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
WO2019232419A1
(en)
|
2018-06-01 |
2019-12-05 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
US20190375749A1
(en)
|
2018-06-11 |
2019-12-12 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
WO2020050890A2
(en)
|
2018-06-12 |
2020-03-12 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
WO2020023782A1
(en)
|
2018-07-27 |
2020-01-30 |
Biotheryx, Inc. |
Bifunctional compounds as cdk modulators
|
KR20210111247A
(ko)
|
2018-11-08 |
2021-09-10 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 및 t 세포 조절을 위한 방법 및 조합
|
JP2020090482A
(ja)
|
2018-11-16 |
2020-06-11 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
SG11202105084VA
(en)
|
2018-11-16 |
2021-06-29 |
Juno Therapeutics Inc |
Methods of dosing engineered t cells for the treatment of b cell malignancies
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
AU2019384118A1
(en)
|
2018-11-19 |
2021-05-27 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
CA3120869A1
(en)
|
2018-11-30 |
2020-06-04 |
Juno Therapeutics, Inc. |
Methods for treatment using adoptive cell therapy
|
MX2021007158A
(es)
|
2018-12-20 |
2021-08-16 |
Amgen Inc |
Heteroarilamidas utiles como inhibidores de kif18a.
|
EP3897855B1
(en)
|
2018-12-20 |
2023-06-07 |
Amgen Inc. |
Kif18a inhibitors
|
EP3898592A1
(en)
|
2018-12-20 |
2021-10-27 |
Amgen Inc. |
Heteroaryl amides useful as kif18a inhibitors
|
EA202191730A1
(ru)
|
2018-12-20 |
2021-08-24 |
Эмджен Инк. |
Ингибиторы kif18a
|
AR119683A1
(es)
|
2019-01-29 |
2022-01-05 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígeno quimérico específicos para receptor huérfano 1 similar a receptor de tirosina quinasa (ror1)
|
EP3931195A1
(en)
|
2019-03-01 |
2022-01-05 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
AU2020232616A1
(en)
|
2019-03-01 |
2021-09-09 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
EP3972973A1
(en)
|
2019-05-21 |
2022-03-30 |
Amgen Inc. |
Solid state forms
|
EP4007752A1
(en)
|
2019-08-02 |
2022-06-08 |
Amgen Inc. |
Kif18a inhibitors
|
CA3147276A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
WO2021026101A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
WO2021081212A1
(en)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
|
JP2022553859A
(ja)
|
2019-11-04 |
2022-12-26 |
レボリューション メディシンズ インコーポレイテッド |
Ras阻害剤
|
BR112022008534A2
(pt)
|
2019-11-04 |
2022-08-09 |
Revolution Medicines Inc |
Compostos, composição farmacêutica, conjugado e métodos para tratar câncer e para tratar um distúrbio relacionado à proteína ras
|
BR112022008858A2
(pt)
|
2019-11-08 |
2022-09-06 |
Revolution Medicines Inc |
Composto, composição farmacêutica e métodos para inibir sos1 em um sujeito, para inibir a interação de sos1 e uma proteína, para tratar ou prevenir uma doença e para tratar ou prevenir câncer
|
JP2023501522A
(ja)
|
2019-11-14 |
2023-01-18 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の改良合成法
|
CN114728960A
(zh)
|
2019-11-14 |
2022-07-08 |
美国安进公司 |
Kras g12c抑制剂化合物的改善的合成
|
JP2023505100A
(ja)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
共有ras阻害剤及びその使用
|
IL294484A
(en)
|
2020-01-07 |
2022-09-01 |
Revolution Medicines Inc |
Dosage for shp2 inhibitor and methods for treating cancer
|
EP4143329A2
(en)
|
2020-04-28 |
2023-03-08 |
Anwita Biosciences, Inc. |
Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications
|
IL299131A
(en)
|
2020-06-18 |
2023-02-01 |
Revolution Medicines Inc |
Methods for delaying, preventing and treating acquired resistance to RAS inhibitors
|
WO2022060583A1
(en)
|
2020-09-03 |
2022-03-24 |
Revolution Medicines, Inc. |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
US11690915B2
(en)
|
2020-09-15 |
2023-07-04 |
Revolution Medicines, Inc. |
Ras inhibitors
|
CN117396472A
(zh)
|
2020-12-22 |
2024-01-12 |
上海齐鲁锐格医药研发有限公司 |
Sos1抑制剂及其用途
|
WO2022235870A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
JP2024516450A
(ja)
|
2021-05-05 |
2024-04-15 |
レボリューション メディシンズ インコーポレイテッド |
共有結合性ras阻害剤及びその使用
|
AR125782A1
(es)
|
2021-05-05 |
2023-08-16 |
Revolution Medicines Inc |
Inhibidores de ras
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
WO2024081916A1
(en)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|
WO2024097905A1
(en)
|
2022-11-02 |
2024-05-10 |
Celgene Corporation |
Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
|