NZ193252A - 4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions - Google Patents

4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions

Info

Publication number
NZ193252A
NZ193252A NZ193252A NZ19325280A NZ193252A NZ 193252 A NZ193252 A NZ 193252A NZ 193252 A NZ193252 A NZ 193252A NZ 19325280 A NZ19325280 A NZ 19325280A NZ 193252 A NZ193252 A NZ 193252A
Authority
NZ
New Zealand
Prior art keywords
ethyl
amino
methoxy
quinolinecarboxylate
compound
Prior art date
Application number
NZ193252A
Other languages
English (en)
Inventor
Jr H R Munson
R S Alpin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of NZ193252A publication Critical patent/NZ193252A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ193252A 1979-03-26 1980-03-25 4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions NZ193252A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (1)

Publication Number Publication Date
NZ193252A true NZ193252A (en) 1984-04-27

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ193252A NZ193252A (en) 1979-03-26 1980-03-25 4-amino-3-quinoline carboxylic acid derivatives and pharmaceutical compositions

Country Status (31)

Country Link
US (1) US4343804A (OSRAM)
JP (1) JPH02117663A (OSRAM)
AR (1) AR230268A1 (OSRAM)
AT (1) AT372373B (OSRAM)
AU (1) AU528388B2 (OSRAM)
BR (1) BR8001779A (OSRAM)
CA (1) CA1147338A (OSRAM)
CH (1) CH644105A5 (OSRAM)
DE (1) DE3011490A1 (OSRAM)
DK (1) DK156056C (OSRAM)
EG (1) EG15009A (OSRAM)
ES (1) ES8103048A1 (OSRAM)
FI (1) FI77452C (OSRAM)
FR (1) FR2452485B1 (OSRAM)
GB (1) GB2047244B (OSRAM)
GR (1) GR68006B (OSRAM)
HK (1) HK67983A (OSRAM)
IE (1) IE49577B1 (OSRAM)
IL (1) IL59628A (OSRAM)
IN (1) IN151446B (OSRAM)
IT (1) IT1133079B (OSRAM)
MX (1) MX6264E (OSRAM)
NL (1) NL8001752A (OSRAM)
NO (1) NO153927C (OSRAM)
NZ (1) NZ193252A (OSRAM)
PH (1) PH16416A (OSRAM)
PL (1) PL125030B1 (OSRAM)
PT (1) PT71008B (OSRAM)
SE (1) SE435837B (OSRAM)
SG (1) SG33683G (OSRAM)
YU (1) YU41702B (OSRAM)

Families Citing this family (44)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
AU682051B2 (en) * 1993-08-10 1997-09-18 James Black Foundation Limited Gastrin and CCK receptor ligands
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
DK2253620T3 (da) 1998-09-29 2014-03-31 Wyeth Holdings Llc Substituerede 3-cyanoquinoliner som protein-tyrosinkinase-inhibitorer
CA2395772C (en) * 1999-12-28 2010-09-28 Eisai Co., Ltd. Sulfonamide-containing heterocyclic compounds
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
PT1599468E (pt) 2003-01-14 2008-01-14 Arena Pharm Inc Derivados de arilo e heteroarilo 1,2,3.-trissubstituídos comomoduladores do metabolismo, e profilaxia e tratamento dedesordens relacionadas tais como diabetes e hiperglicemia
MXPA04008070A (es) 2003-03-10 2004-11-26 Altana Pharma Ag Novedoso proceso para la preparacion de roflumilasto.
EP2287165A3 (en) * 2003-07-14 2011-06-22 Arena Pharmaceuticals, Inc. Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
JP5941916B2 (ja) 2010-09-22 2016-06-29 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
DK3310760T3 (da) 2015-06-22 2022-10-24 Arena Pharm Inc Krystallinsk L-argininsalt af (R)-2-(7-(4-cyclopentyl-3-(trifluormethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3- yl)eddikesyre til anvendelse ved S1P1-receptor-associerede lidelser
EP3538512B1 (en) * 2016-11-11 2021-06-16 Bayer Animal Health GmbH New anthelmintic quinoline-3-carboxamide derivatives
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
WO2019084271A1 (en) * 2017-10-25 2019-05-02 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHODS OF USE
AU2019266511B2 (en) 2018-05-09 2022-12-08 Elanco Animal Health Gmbh New quinoline derivatives
BR112020024762A2 (pt) 2018-06-06 2021-03-23 Arena Pharmaceuticals, Inc. métodos de tratamento de condições relacionadas ao receptor s1p1
CN113993848A (zh) 2019-04-24 2022-01-28 儿童医学中心公司 Papd5抑制剂及其使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (OSRAM) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
FI77452B (fi) 1988-11-30
IT8067465A0 (it) 1980-03-26
AT372373B (de) 1983-09-26
SE435837B (sv) 1984-10-22
DE3011490A1 (de) 1981-03-12
AU528388B2 (en) 1983-04-28
FI800910A7 (fi) 1980-09-27
IT1133079B (it) 1986-07-09
YU41702B (en) 1987-12-31
CH644105A5 (fr) 1984-07-13
EG15009A (en) 1985-03-31
IN151446B (OSRAM) 1983-04-23
GB2047244B (en) 1983-02-23
HK67983A (en) 1983-12-23
DE3011490C2 (OSRAM) 1988-12-22
YU84480A (en) 1983-10-31
PL222993A1 (OSRAM) 1981-01-30
PL125030B1 (en) 1983-03-31
ES489887A0 (es) 1981-02-16
AR230268A1 (es) 1984-03-01
DK128380A (da) 1980-09-27
IL59628A (en) 1983-06-15
NO153927B (no) 1986-03-10
IE49577B1 (en) 1985-10-30
NL8001752A (nl) 1980-09-30
PH16416A (en) 1983-09-29
NO153927C (no) 1986-06-18
PT71008A (en) 1980-04-01
MX6264E (es) 1985-02-19
PT71008B (en) 1981-06-25
JPH02117663A (ja) 1990-05-02
NO800858L (no) 1980-09-29
FR2452485B1 (fr) 1986-09-12
IL59628A0 (en) 1980-06-30
SE8002292L (sv) 1980-09-27
IE800605L (en) 1980-09-26
AU5684880A (en) 1980-10-02
BR8001779A (pt) 1980-11-18
ES8103048A1 (es) 1981-02-16
GB2047244A (en) 1980-11-26
ATA156480A (de) 1983-02-15
SG33683G (en) 1985-03-29
FR2452485A1 (fr) 1980-10-24
FI77452C (fi) 1989-03-10
DK156056C (da) 1989-11-06
GR68006B (OSRAM) 1981-10-26
CA1147338A (en) 1983-05-31
US4343804A (en) 1982-08-10
DK156056B (da) 1989-06-19

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