NO960956D0 - Rekombinante IL4-antistoffer anvendelige ved behandling av IL4-betingede forstyrrelser - Google Patents

Rekombinante IL4-antistoffer anvendelige ved behandling av IL4-betingede forstyrrelser

Info

Publication number
NO960956D0
NO960956D0 NO960956A NO960956A NO960956D0 NO 960956 D0 NO960956 D0 NO 960956D0 NO 960956 A NO960956 A NO 960956A NO 960956 A NO960956 A NO 960956A NO 960956 D0 NO960956 D0 NO 960956D0
Authority
NO
Norway
Prior art keywords
recombinant
treatment
related disorders
antibodies useful
antibodies
Prior art date
Application number
NO960956A
Other languages
English (en)
Other versions
NO960956L (no
Inventor
Stephen Dudley Holmes
Mitchell Stuart Gross
Daniel R Sylvester
Original Assignee
Smithkline Beecham Corp
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Smithkline Beecham Plc filed Critical Smithkline Beecham Corp
Publication of NO960956D0 publication Critical patent/NO960956D0/no
Publication of NO960956L publication Critical patent/NO960956L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/247IL-4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO960956A 1993-09-07 1996-03-07 Rekombinante IL4-antistoffer anvendelige ved behandling av IL4-betingede forstyrrelser NO960956L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11736693A 1993-09-07 1993-09-07
US13678393A 1993-10-14 1993-10-14
PCT/US1994/010308 WO1995007301A1 (en) 1993-09-07 1994-09-07 Recombinant il4 antibodies useful in treatment of il4 mediated disorders

Publications (2)

Publication Number Publication Date
NO960956D0 true NO960956D0 (no) 1996-03-07
NO960956L NO960956L (no) 1996-05-06

Family

ID=26815208

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960956A NO960956L (no) 1993-09-07 1996-03-07 Rekombinante IL4-antistoffer anvendelige ved behandling av IL4-betingede forstyrrelser

Country Status (21)

Country Link
EP (1) EP0730609B1 (no)
JP (4) JPH09502708A (no)
KR (1) KR100362340B1 (no)
CN (2) CN1105728C (no)
AP (1) AP583A (no)
AT (1) ATE286510T1 (no)
AU (1) AU695726B2 (no)
BG (1) BG63549B1 (no)
BR (1) BR9407575A (no)
CA (1) CA2171336C (no)
CZ (1) CZ295928B6 (no)
DE (1) DE69434223T2 (no)
ES (1) ES2236693T3 (no)
FI (1) FI119733B (no)
HU (1) HU222041B1 (no)
NO (1) NO960956L (no)
NZ (1) NZ274338A (no)
PL (1) PL180125B1 (no)
SK (1) SK285556B6 (no)
UA (1) UA48940C2 (no)
WO (1) WO1995007301A1 (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
US6768004B2 (en) * 2001-01-11 2004-07-27 Mueller Sybille Nucleotide sequences encoding variable regions of heavy and light chains of monoclonal antibody 1F7, an anti-idiotypic antibody reactive with anti-HIV antibodies
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
TWI374893B (en) * 2003-05-30 2012-10-21 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
US20060122377A1 (en) 2004-02-19 2006-06-08 Genentech, Inc. CDR-repaired antibodies
AR050044A1 (es) * 2004-08-03 2006-09-20 Novartis Ag Anticuerpo especifico de il-4
US8916165B2 (en) 2004-12-15 2014-12-23 Janssen Alzheimer Immunotherapy Humanized Aβ antibodies for use in improving cognition
WO2007107349A1 (en) * 2006-03-22 2007-09-27 Apogenix Gmbh Antibody specific for human il-4 for the treament of cancer
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
BRPI0713484A2 (pt) 2006-06-21 2012-11-06 Apogenix Gmbh expressão diferencial de citocina em cáncer humano
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
JP4971872B2 (ja) 2007-05-23 2012-07-11 株式会社トプコン 眼底観察装置及びそれを制御するプログラム
DK2182983T3 (da) 2007-07-27 2014-07-14 Janssen Alzheimer Immunotherap Behandling af amyloidogene sygdomme med humaniserede anti-abeta antistoffer
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
JP5324839B2 (ja) 2008-06-19 2013-10-23 株式会社トプコン 光画像計測装置
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
CN102294024B (zh) * 2011-01-17 2013-03-13 广东现代农业集团研究院有限公司 一种多肽疫苗及其制备方法
US10336816B2 (en) * 2015-02-24 2019-07-02 Academia Sinica Phage-displayed single-chain variable fragment library
CN113156134B (zh) * 2020-11-26 2024-01-23 江苏荃信生物医药股份有限公司 用于检测人白介素23的elisa试剂盒及检测方法
CN114891112A (zh) * 2020-12-31 2022-08-12 中元汇吉生物技术股份有限公司 特异性结合人IgG4的蛋白及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5041381A (en) * 1986-07-03 1991-08-20 Schering Corporation Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
JP2646007B2 (ja) * 1988-01-30 1997-08-25 財団法人 化学及血清療法研究所 抗hiv抗体可変領域をコードする遺伝子断片およびこれらを用いて発現された抗hivキメラ抗体ならびにその製法
EP0365209A3 (en) * 1988-10-17 1990-07-25 Becton, Dickinson and Company Anti-leu 3a amino acid sequence
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
JPH07119238B2 (ja) * 1989-12-18 1995-12-20 小野薬品工業株式会社 ヒトインターロイキン―4に対するモノクローナル抗体および該抗体の利用方法
ZA9010190B (en) * 1989-12-20 1991-08-28 Schering Corp Antibody antagonists of human interleukin-4
JPH04141095A (ja) * 1990-10-02 1992-05-14 Chemo Sero Therapeut Res Inst 組換え抗hiv改変抗体および改変抗体の調製方法
ZA931148B (en) * 1992-02-19 1993-08-18 Schering Corp Cloning and expression of humanized monoclonal antibodies against human interfluekin-4.
JPH06269663A (ja) * 1993-03-17 1994-09-27 Toyobo Co Ltd Cd4陽性細胞捕集材
ES2254207T3 (es) * 1999-07-30 2006-06-16 Battelle Memorial Institute Material de union vitroceramico y procedimiento de union.

Also Published As

Publication number Publication date
JP2009191077A (ja) 2009-08-27
EP0730609A1 (en) 1996-09-11
JPH09502708A (ja) 1997-03-18
CA2171336A1 (en) 1995-03-16
SK33396A3 (en) 1996-10-02
CN1133599A (zh) 1996-10-16
CZ69896A3 (en) 1996-10-16
NZ274338A (en) 1998-02-26
HUT75833A (en) 1997-05-28
CZ295928B6 (cs) 2005-12-14
PL313491A1 (en) 1996-07-08
EP0730609B1 (en) 2005-01-05
BG63549B1 (bg) 2002-04-30
AU695726B2 (en) 1998-08-20
DE69434223D1 (de) 2005-02-10
FI119733B (fi) 2009-02-27
ES2236693T3 (es) 2005-07-16
KR100362340B1 (ko) 2003-02-26
ATE286510T1 (de) 2005-01-15
NO960956L (no) 1996-05-06
HU222041B1 (hu) 2003-04-28
CA2171336C (en) 2011-06-21
UA48940C2 (uk) 2002-09-16
DE69434223T2 (de) 2005-12-22
BG100480A (bg) 1996-12-31
PL180125B1 (pl) 2000-12-29
WO1995007301A1 (en) 1995-03-16
JP2006333870A (ja) 2006-12-14
HU9600616D0 (en) 1996-05-28
AP583A (en) 1997-04-14
EP0730609A4 (en) 2000-05-10
CN1105728C (zh) 2003-04-16
AU7834094A (en) 1995-03-27
SK285556B6 (sk) 2007-03-01
AP9600782A0 (en) 1996-04-30
FI961083A (fi) 1996-05-06
JP2007045831A (ja) 2007-02-22
FI961083A0 (fi) 1996-03-07
CN1473854A (zh) 2004-02-11
BR9407575A (pt) 1996-07-16

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