NO940635L - - Google Patents

Info

Publication number
NO940635L
NO940635L NO940635A NO940635A NO940635L NO 940635 L NO940635 L NO 940635L NO 940635 A NO940635 A NO 940635A NO 940635 A NO940635 A NO 940635A NO 940635 L NO940635 L NO 940635L
Authority
NO
Norway
Prior art keywords
sub
compound
enzyme
sulphate
steroid sulphatase
Prior art date
Application number
NO940635A
Other languages
English (en)
Norwegian (no)
Other versions
NO940635D0 (no
NO307301B1 (no
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO940635D0 publication Critical patent/NO940635D0/no
Publication of NO940635L publication Critical patent/NO940635L/no
Publication of NO307301B1 publication Critical patent/NO307301B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36Antigestagens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Surgical Instruments (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO940635A 1991-08-29 1994-02-24 Anvendelse av en forbindelse for fremstilling av et medikament for å inhibere steroidsulfataseaktivitet NO307301B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919118478A GB9118478D0 (en) 1991-08-29 1991-08-29 Steroid sulphatase inhibitors
PCT/GB1992/001587 WO1993005064A1 (fr) 1991-08-29 1992-08-28 Inhibiteurs de sulfatase steroidienne

Publications (3)

Publication Number Publication Date
NO940635D0 NO940635D0 (no) 1994-02-24
NO940635L true NO940635L (fr) 1994-04-29
NO307301B1 NO307301B1 (no) 2000-03-13

Family

ID=10700604

Family Applications (6)

Application Number Title Priority Date Filing Date
NO940635A NO307301B1 (no) 1991-08-29 1994-02-24 Anvendelse av en forbindelse for fremstilling av et medikament for å inhibere steroidsulfataseaktivitet
NO995075A NO308903B1 (no) 1991-08-29 1999-10-18 Steroid-sulfataseinhibitorer
NO995076A NO308774B1 (no) 1991-08-29 1999-10-18 Farmasøytisk preparat
NO20002595A NO314287B1 (no) 1991-08-29 2000-05-19 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament
NO20025725A NO318009B1 (no) 1991-08-29 2002-11-28 Forbindelse, farmasoytisk preparat inneholdende den samme samt anvendelse derav
NO20044458A NO20044458L (no) 1991-08-29 2004-10-20 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament

Family Applications After (5)

Application Number Title Priority Date Filing Date
NO995075A NO308903B1 (no) 1991-08-29 1999-10-18 Steroid-sulfataseinhibitorer
NO995076A NO308774B1 (no) 1991-08-29 1999-10-18 Farmasøytisk preparat
NO20002595A NO314287B1 (no) 1991-08-29 2000-05-19 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament
NO20025725A NO318009B1 (no) 1991-08-29 2002-11-28 Forbindelse, farmasoytisk preparat inneholdende den samme samt anvendelse derav
NO20044458A NO20044458L (no) 1991-08-29 2004-10-20 Anvendelse av en ringsystemforbindelse for fremstilling av et medikament

Country Status (26)

Country Link
US (3) US5616574A (fr)
EP (6) EP0982032B1 (fr)
JP (6) JP3219408B2 (fr)
KR (4) KR100258396B1 (fr)
AT (5) ATE278704T1 (fr)
AU (2) AU689043B2 (fr)
BR (1) BR9206434A (fr)
CA (4) CA2305758A1 (fr)
CY (4) CY2253B1 (fr)
CZ (1) CZ295939B6 (fr)
DE (5) DE69233149T2 (fr)
DK (4) DK0921130T3 (fr)
ES (4) ES2193475T3 (fr)
FI (5) FI940903A (fr)
GB (1) GB9118478D0 (fr)
GE (6) GEP20022637B (fr)
GR (1) GR3034579T3 (fr)
HK (3) HK1019753A1 (fr)
HU (1) HUT66097A (fr)
LV (1) LV12618B (fr)
NO (6) NO307301B1 (fr)
RU (4) RU2001125673A (fr)
SG (7) SG115508A1 (fr)
SK (4) SK282189B6 (fr)
UA (4) UA41875C2 (fr)
WO (1) WO1993005064A1 (fr)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011024A (en) * 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
GB9603325D0 (en) * 1996-02-16 1996-04-17 Imperial College A compound
GB9625334D0 (en) * 1996-12-05 1997-01-22 Imperial College Compound
US6083978A (en) * 1996-03-05 2000-07-04 Sterix Limited Compounds with a sulfamate group
GB9118478D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
GB9604709D0 (en) * 1996-03-05 1996-05-01 Imperial College A compound
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
US6903084B2 (en) 1991-08-29 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
WO1995026717A1 (fr) * 1994-04-05 1995-10-12 Celltech Therapeutics Limited Utilisation de derives d'estrone comme inhibiteurs de la sulfatase de steroïdes
DE4447715C2 (de) * 1994-08-09 1998-02-05 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Behandlung von Prostatakarzinomen
DE4429397C2 (de) * 1994-08-09 2003-11-20 Jenapharm Gmbh Estra-1,3,5(10)-trien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
GB9422777D0 (en) * 1994-11-11 1995-01-04 Imperial College Assay
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
US5705495A (en) * 1995-10-19 1998-01-06 Jenapharm Gmbh & Co. Kg. Sulfamate derivatives of 1,3,5(10)-estratriene derivatives, methods for their production and pharmaceuticals containing these compounds
US6506792B1 (en) 1997-03-04 2003-01-14 Sterix Limited Compounds that inhibit oestrone sulphatase and/or aromatase and methods for making and using
US6921776B1 (en) 1996-02-16 2005-07-26 Sterix Limited Compound
EP0934949A1 (fr) * 1996-09-12 1999-08-11 Teikoku Hormone Mfg. Co., Ltd. Derives d'oestrariene a trisubstitution-d-homo-1,3,5,(10)
US20040127473A1 (en) * 1996-12-05 2004-07-01 Reed Michael John Compound
US6642220B1 (en) * 1996-12-05 2003-11-04 Sterix Limited Compounds that inhibit oestrone sulphatase; compositions thereof; and methods employing the same
US5763432A (en) * 1997-01-29 1998-06-09 Sri International Steriod inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
DE19712488A1 (de) 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroidsulfamate, Verfahren zu ihrer Herstellung und Anwendung derselben
GB9708716D0 (en) * 1997-04-29 1997-06-18 Imperial College Chronic heart failure
US6288050B1 (en) 1997-07-18 2001-09-11 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
US6376687B1 (en) 1997-07-18 2002-04-23 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
US5880115A (en) * 1997-07-18 1999-03-09 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
GB2331987B (en) * 1997-12-04 2002-11-27 Imperial College Polycyclic sulphamate inhibitors of oestrone sulphatase
GB2331988B (en) * 1997-12-04 2003-04-16 Imperial College Polycyclic sulphamate inhibitors or oestrone sulphatase
US6046186A (en) * 1997-12-24 2000-04-04 Sri International Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use
GB9807779D0 (en) 1998-04-09 1998-06-10 Ciba Geigy Ag Organic compounds
WO1999061055A1 (fr) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Molecules bifonctionnelles et therapies basees sur celles-ci
AU765386B2 (en) * 1998-06-10 2003-09-18 Sterix Limited Pharmaceutical composition with tumor necrosis factor a and 2-methoxyestrone-3-(o)-sulphamate for inhibition of estrone sulphatase
US6248780B1 (en) 1998-10-01 2001-06-19 Duquesne University Of The Holy Ghost Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
WO2000053620A1 (fr) * 1999-03-10 2000-09-14 Nippon Organon K. K. Nouveaux derives d'oestradiol
JP2000309599A (ja) 1999-04-13 2000-11-07 Kyowa Hakko Kogyo Co Ltd エストラ−1,3,5(10),16−テトラエン誘導体
AU783910B2 (en) * 1999-04-30 2005-12-22 Sterix Limited Use of estrone derivatives as antitumour agents
US7078395B1 (en) 1999-06-16 2006-07-18 Sterix Limited Methods for treating or preventing cancer by preventing, inhibiting or arresting cell cycling
AU2005225148B2 (en) * 1999-04-30 2008-04-03 Sterix Limited Use
GB9913536D0 (en) * 1999-06-10 1999-08-11 Sterix Ltd Use
US6583130B1 (en) 1999-09-13 2003-06-24 Schering Ag C13-substituted estra-1,3,5,(10)-trien-3-yl sulfamates, methods of preparing same, and pharmaceutical compositions containing these compounds
ES2250224T3 (es) * 1999-12-13 2006-04-16 Sterix Limited Compuestos halogenos de sulfamato, fosfonato, tiofosfonato, sulfonato y sulfonamida como inhibidores de sulfatasa esteoride.
US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
US6953785B2 (en) * 2000-04-24 2005-10-11 Kyowa Hakko Kogyo Co., Ltd. Estra-1,3,5(10)-triene derivatives
DE10027887A1 (de) * 2000-05-31 2001-12-13 Jenapharm Gmbh Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
GB0020498D0 (en) * 2000-08-18 2000-10-11 Sterix Ltd Compound
EP1406634A1 (fr) 2001-07-13 2004-04-14 Schering Aktiengesellschaft Combinaison de drospirenone et d'un sulfamate d'oestrogene destinee a une hormonotherapie substitutive
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
DE10139494A1 (de) * 2001-08-13 2003-03-06 Jenapharm Gmbh Antitumor wirksame 2-Alkoxyestradiolsulfamate
US8026229B2 (en) 2001-08-13 2011-09-27 Sterix Limited Antitumor-active 2-alkoxyestradiol sulfamates
PT1448592E (pt) * 2001-10-18 2006-07-31 Sterix Ltd Compostos esteroides para inibicao da esteroide sulfatase
CA2463227C (fr) 2001-10-18 2010-08-10 Sterix Limited Composes steroidiens inhibiteurs de la steroide sulfatase
US20040254241A1 (en) * 2002-08-28 2004-12-16 Yoji Ino Aryl sulfamate derivatives
CA2501556A1 (fr) * 2002-10-09 2004-04-29 Kyowa Hakko Kogyo Co., Ltd. Remede destine a un cancer hormono-dependant
DE10307104A1 (de) 2003-02-19 2004-09-23 Schering Ag Antitumor wirksame 2-substituierte Estra-1,3,5(10)-trien-3-yl sulfamate
DE10307105A1 (de) * 2003-02-19 2004-09-09 Schering Ag Antitumor wirksame 2-substituierte 18a-Homoestra-1,3,5(10)-trien-3-yl sulfamate
DE10307103A1 (de) * 2003-02-19 2004-09-09 Schering Ag Antitumor wirksame 2-substituierte D-Homostra-1,3,5(10)-trien-3-yl sulfamate
CA2525684C (fr) * 2003-05-16 2015-01-06 Laboratoire Theramex Derives de sulfamate benzothiophene utilises en tant qu'inhibiteurs de la steroide sulfatase
ATE464293T1 (de) 2003-05-21 2010-04-15 Aska Pharm Co Ltd Cyclisches aminophenylsulfamatderivativ
US7534780B2 (en) 2004-05-21 2009-05-19 Bayer Schering Pharma Aktiengesellschaft Estradiol prodrugs
GB0412492D0 (en) 2004-06-04 2004-07-07 Sterix Ltd Compound
WO2006116718A2 (fr) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Systeme pharma-informatique
US8030298B2 (en) 2005-05-26 2011-10-04 Abbott Products Gmbh 17β-HSD1 and STS inhibitors
GB0511190D0 (en) * 2005-06-01 2005-07-06 Sterix Ltd Use
WO2007035716A2 (fr) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions de proteines rap specifiques des proteines contenant du cr, et leurs utilisations
GB0624105D0 (en) * 2006-12-01 2007-01-10 Sterix Ltd Use
GB0706072D0 (en) 2007-03-28 2007-05-09 Sterix Ltd Compound
EP2207544A2 (fr) 2007-09-17 2010-07-21 PregLem S.A. Traitement d'états pathologiques strogénodépendants chez des femmes pré-ménopausées
EP2149371A1 (fr) * 2008-07-28 2010-02-03 PregLem S.A. Utilisation d'inhibiteurs de sulfatase de stéroïde pour le traitement des accouchements prématurés
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EA024559B1 (ru) 2009-05-06 2016-09-30 Лаборэтори Скин Кэа, Инк. Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки
GB0914767D0 (en) 2009-08-24 2009-09-30 Sterix Ltd Compound
CN110974840A (zh) * 2019-12-27 2020-04-10 天津市肿瘤医院 一种类固醇硫酸酯酶抑制剂及其药物用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE114806C (fr) *
DE1593846A1 (de) * 1967-01-28 1971-02-25 Hoechst Ag Verfahren zur Herstellung von Sulfamidsaeure-arylestern
US3647738A (en) * 1970-11-03 1972-03-07 Union Carbide Corp Alpha-olefin polymer compositions
GB1398026A (en) * 1972-11-10 1975-06-18 Jenapharm Veb Steroid esters
DE2418217A1 (de) * 1974-04-13 1975-11-06 Hoechst Ag Sulfamidsaeureester und verfahren zu ihrer herstellung
DD114806A1 (fr) * 1974-10-11 1975-08-20
US4937237A (en) * 1988-12-23 1990-06-26 Smithkline Beckman Corporation Phosphinic acid substituted aromatic steroids as inhibitors of steroid 5-60 -reductase
PT94305B (pt) * 1989-06-12 1997-02-28 Robins Co Inc A H Processo para a preparacao de compostos tendo um ou mais radicais aminossulfoniloxi uteis como produtos farmaceuticos
GB9003939D0 (en) * 1990-02-21 1990-04-18 Imperial College Sulphatase inhibitors
GB9603325D0 (en) * 1996-02-16 1996-04-17 Imperial College A compound
GB9625334D0 (en) * 1996-12-05 1997-01-22 Imperial College Compound
GB9118478D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
US6083978A (en) * 1996-03-05 2000-07-04 Sterix Limited Compounds with a sulfamate group
GB9118465D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
US5880115A (en) * 1997-07-18 1999-03-09 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same

Also Published As

Publication number Publication date
AU668882B2 (en) 1996-05-23
FI20002259A (fi) 2000-10-13
GEP20033094B (en) 2003-10-27
DE69233020T2 (de) 2003-11-06
DK0921130T3 (da) 2003-07-21
SG106116A1 (en) 2004-09-30
EP0641355A1 (fr) 1995-03-08
RU2001125673A (ru) 2003-06-27
BR9206434A (pt) 1994-09-27
CY2397B1 (en) 2004-09-10
CZ295939B6 (cs) 2005-12-14
ATE246706T1 (de) 2003-08-15
DE69233431D1 (de) 2004-11-11
DK0641355T3 (da) 2000-10-09
GEP20063773B (en) 2006-03-27
SK282187B6 (sk) 2001-12-03
CA2114630C (fr) 2003-09-30
GEP20022803B (en) 2002-09-25
JP2003176297A (ja) 2003-06-24
EP1099706B1 (fr) 2004-10-06
GEP20022802B (en) 2002-09-25
EP0982032B1 (fr) 2003-08-06
CY2253B1 (en) 2003-07-04
JP2000038341A (ja) 2000-02-08
AU2490592A (en) 1993-04-05
ES2204059T3 (es) 2004-04-16
EP0641355B1 (fr) 2000-07-19
FI20002260A (fi) 2000-10-13
KR100322650B1 (ko) 2002-03-20
GB9118478D0 (en) 1991-10-16
NO308774B1 (no) 2000-10-30
LV12618B (en) 2001-07-20
CA2305758A1 (fr) 1993-03-18
JPH07501515A (ja) 1995-02-16
CA2305767A1 (fr) 1993-03-18
DE69233020D1 (de) 2003-05-22
EP0921130A3 (fr) 2001-09-05
UA41875C2 (uk) 2001-10-15
AU717116B2 (en) 2000-03-16
DE69231280D1 (de) 2000-08-24
NO20025725D0 (no) 2002-11-28
WO1993005064A1 (fr) 1993-03-18
FI940903A0 (fi) 1994-02-25
JP2000355542A (ja) 2000-12-26
EP1099706A2 (fr) 2001-05-16
SG88783A1 (en) 2002-05-21
CY2398B1 (en) 2004-09-10
FI20050991A (fi) 2005-10-03
ES2196483T3 (es) 2003-12-16
NO20025725L (no) 1994-04-29
US5616574A (en) 1997-04-01
FI20002261A (fi) 2000-10-13
SG103374A1 (en) 2004-04-29
JP3581821B2 (ja) 2004-10-27
LV12618A (en) 2001-02-20
FI940903A (fi) 1994-04-20
SK282186B6 (sk) 2001-12-03
CA2305749A1 (fr) 1993-03-18
CZ44094A3 (en) 1995-01-18
NO995076L (no) 1994-04-29
US5830886A (en) 1998-11-03
EP1522543A1 (fr) 2005-04-13
DE69231280T2 (de) 2000-11-30
ATE237333T1 (de) 2003-05-15
EP0928609A3 (fr) 2001-11-07
RU2207134C2 (ru) 2003-06-27
DK0928609T3 (da) 2003-07-21
RU2210574C2 (ru) 2003-08-20
CA2114630A1 (fr) 1993-03-18
DK0982032T3 (da) 2003-11-03
UA70957C2 (uk) 2004-11-15
JP3581820B2 (ja) 2004-10-27
NO995076D0 (no) 1999-10-18
KR100321018B1 (ko) 2002-03-20
HU9400583D0 (en) 1994-05-30
SK24694A3 (en) 1994-11-09
NO940635D0 (no) 1994-02-24
EP0921130A2 (fr) 1999-06-09
JP3581802B2 (ja) 2004-10-27
JP2000355598A (ja) 2000-12-26
ES2193475T3 (es) 2003-11-01
JP3219408B2 (ja) 2001-10-15
DE69233053T2 (de) 2003-11-20
ATE194843T1 (de) 2000-08-15
HK1020672A1 (en) 2000-05-19
EP0921130B1 (fr) 2003-05-07
EP0982032A2 (fr) 2000-03-01
DE69233053D1 (de) 2003-06-12
SG73391A1 (en) 2006-08-30
ES2148178T3 (es) 2000-10-16
KR100258396B1 (ko) 2000-08-01
UA70956C2 (uk) 2004-11-15
RU2182152C2 (ru) 2002-05-10
DE69233149D1 (de) 2003-09-11
EP0928609B1 (fr) 2003-04-16
RU94019334A (ru) 1996-10-20
UA70958C2 (uk) 2004-11-15
SG88782A1 (en) 2002-05-21
NO20044458L (no) 1994-04-29
SG103820A1 (en) 2004-05-26
AU5837396A (en) 1996-09-05
JP2002255993A (ja) 2002-09-11
US6159960A (en) 2000-12-12
GR3034579T3 (en) 2001-01-31
DE69233431T2 (de) 2006-02-23
NO308903B1 (no) 2000-11-13
ATE278704T1 (de) 2004-10-15
CY2394B1 (en) 2004-09-10
GEP20022637B (en) 2002-02-25
ATE239753T1 (de) 2003-05-15
HK1019753A1 (en) 2000-02-25
NO318009B1 (no) 2005-01-17
NO995075L (no) 1994-04-29
NO307301B1 (no) 2000-03-13
HUT66097A (en) 1994-09-28
KR100321019B1 (ko) 2002-03-20
EP0982032A3 (fr) 2002-03-20
NO995075D0 (no) 1999-10-18
SK282188B6 (sk) 2001-12-03
AU689043B2 (en) 1998-03-19
NO2595A (no) 1994-04-29
EP0928609A2 (fr) 1999-07-14
NO314287B1 (no) 2003-03-03
AU1007799A (en) 1999-03-04
HK1025051A1 (en) 2000-11-03
SG115508A1 (en) 2005-10-28
GEP20022766B (en) 2002-08-26
EP1099706A3 (fr) 2002-09-04
NO20002595D0 (no) 2000-05-19
SK282189B6 (sk) 2001-12-03
DE69233149T2 (de) 2004-06-24

Similar Documents

Publication Publication Date Title
KR100321019B1 (ko) 스테로이드 설파타제 억제제를 포함하는 조성물