LV12618B - USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS - Google Patents

USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS Download PDF

Info

Publication number
LV12618B
LV12618B LVP-00-131A LV000131A LV12618B LV 12618 B LV12618 B LV 12618B LV 000131 A LV000131 A LV 000131A LV 12618 B LV12618 B LV 12618B
Authority
LV
Latvia
Prior art keywords
oestrone
compound
sulphamate
group
use according
Prior art date
Application number
LVP-00-131A
Other languages
English (en)
Latvian (lv)
Other versions
LV12618A (en
Inventor
Michael John Reed
Barry Victor Lloyd Potter
Original Assignee
Sterix Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterix Limited filed Critical Sterix Limited
Publication of LV12618A publication Critical patent/LV12618A/xx
Publication of LV12618B publication Critical patent/LV12618B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LVP-00-131A 1991-08-29 2000-10-03 USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS LV12618B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919118478A GB9118478D0 (en) 1991-08-29 1991-08-29 Steroid sulphatase inhibitors

Publications (2)

Publication Number Publication Date
LV12618A LV12618A (en) 2001-02-20
LV12618B true LV12618B (en) 2001-07-20

Family

ID=10700604

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-00-131A LV12618B (en) 1991-08-29 2000-10-03 USE OF SULPHAMAT DERIVATIVES FOR STEROIDE SULPHATE INHIBITORS

Country Status (26)

Country Link
US (3) US5616574A (fr)
EP (6) EP1522543A1 (fr)
JP (6) JP3219408B2 (fr)
KR (4) KR100258396B1 (fr)
AT (5) ATE246706T1 (fr)
AU (2) AU689043B2 (fr)
BR (1) BR9206434A (fr)
CA (4) CA2114630C (fr)
CY (4) CY2253B1 (fr)
CZ (1) CZ295939B6 (fr)
DE (5) DE69233431T2 (fr)
DK (4) DK0921130T3 (fr)
ES (4) ES2196483T3 (fr)
FI (5) FI940903A (fr)
GB (1) GB9118478D0 (fr)
GE (6) GEP20022637B (fr)
GR (1) GR3034579T3 (fr)
HK (3) HK1020672A1 (fr)
HU (1) HUT66097A (fr)
LV (1) LV12618B (fr)
NO (6) NO307301B1 (fr)
RU (4) RU2207134C2 (fr)
SG (7) SG115508A1 (fr)
SK (4) SK282189B6 (fr)
UA (4) UA41875C2 (fr)
WO (1) WO1993005064A1 (fr)

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US6903084B2 (en) * 1991-08-29 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
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DE4429398C2 (de) * 1994-08-09 1997-09-11 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Kontrazeption
GB9422777D0 (en) * 1994-11-11 1995-01-04 Imperial College Assay
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US6921776B1 (en) 1996-02-16 2005-07-26 Sterix Limited Compound
ES2233998T3 (es) * 1996-03-05 2005-06-16 Sterix Limited Compuestos que comprenden un grupo sulfamato.
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US6642220B1 (en) 1996-12-05 2003-11-04 Sterix Limited Compounds that inhibit oestrone sulphatase; compositions thereof; and methods employing the same
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US5763432A (en) * 1997-01-29 1998-06-09 Sri International Steriod inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
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US6376687B1 (en) 1997-07-18 2002-04-23 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
US5880115A (en) * 1997-07-18 1999-03-09 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
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ATE401896T1 (de) 1998-06-10 2008-08-15 Sterix Ltd Pharmazeutische zusammensetzungen mit tumor nekrose faktor und 2-methoxyestron-3-o-sulphamat als estrone sulphatasehemmern
US6248780B1 (en) 1998-10-01 2001-06-19 Duquesne University Of The Holy Ghost Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
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AU2005225148B2 (en) * 1999-04-30 2008-04-03 Sterix Limited Use
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US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
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EP1554572B1 (fr) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique
DE10139494A1 (de) * 2001-08-13 2003-03-06 Jenapharm Gmbh Antitumor wirksame 2-Alkoxyestradiolsulfamate
US8026229B2 (en) 2001-08-13 2011-09-27 Sterix Limited Antitumor-active 2-alkoxyestradiol sulfamates
EP1657247B1 (fr) 2001-10-18 2008-09-17 Sterix Limited Composes steroides pour inhiber la sulfatase de steroides
PT1448592E (pt) * 2001-10-18 2006-07-31 Sterix Ltd Compostos esteroides para inibicao da esteroide sulfatase
US20040254241A1 (en) * 2002-08-28 2004-12-16 Yoji Ino Aryl sulfamate derivatives
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Also Published As

Publication number Publication date
RU2207134C2 (ru) 2003-06-27
FI20002261A (fi) 2000-10-13
RU94019334A (ru) 1996-10-20
UA70958C2 (uk) 2004-11-15
HU9400583D0 (en) 1994-05-30
NO995075L (no) 1994-04-29
EP0641355A1 (fr) 1995-03-08
UA70956C2 (uk) 2004-11-15
DE69231280T2 (de) 2000-11-30
BR9206434A (pt) 1994-09-27
RU2210574C2 (ru) 2003-08-20
JPH07501515A (ja) 1995-02-16
CA2305767A1 (fr) 1993-03-18
DE69233020D1 (de) 2003-05-22
HUT66097A (en) 1994-09-28
SG88783A1 (en) 2002-05-21
EP0641355B1 (fr) 2000-07-19
SK282187B6 (sk) 2001-12-03
EP1099706A2 (fr) 2001-05-16
GEP20022803B (en) 2002-09-25
EP0982032A3 (fr) 2002-03-20
NO995076L (no) 1994-04-29
AU689043B2 (en) 1998-03-19
JP2000038341A (ja) 2000-02-08
FI940903A (fi) 1994-04-20
NO20025725L (no) 1994-04-29
EP1522543A1 (fr) 2005-04-13
KR100322650B1 (ko) 2002-03-20
DE69231280D1 (de) 2000-08-24
NO314287B1 (no) 2003-03-03
NO308903B1 (no) 2000-11-13
ES2193475T3 (es) 2003-11-01
EP0982032B1 (fr) 2003-08-06
CY2397B1 (en) 2004-09-10
NO940635D0 (no) 1994-02-24
NO307301B1 (no) 2000-03-13
DE69233431D1 (de) 2004-11-11
ES2204059T3 (es) 2004-04-16
CZ44094A3 (en) 1995-01-18
CZ295939B6 (cs) 2005-12-14
SK24694A3 (en) 1994-11-09
CA2305749A1 (fr) 1993-03-18
CA2114630C (fr) 2003-09-30
EP1099706B1 (fr) 2004-10-06
SK282186B6 (sk) 2001-12-03
LV12618A (en) 2001-02-20
EP0928609A2 (fr) 1999-07-14
NO20025725D0 (no) 2002-11-28
AU2490592A (en) 1993-04-05
CY2394B1 (en) 2004-09-10
FI20002259A (fi) 2000-10-13
CY2398B1 (en) 2004-09-10
HK1025051A1 (en) 2000-11-03
CA2305758A1 (fr) 1993-03-18
SG106116A1 (en) 2004-09-30
WO1993005064A1 (fr) 1993-03-18
EP1099706A3 (fr) 2002-09-04
GEP20022637B (en) 2002-02-25
ATE278704T1 (de) 2004-10-15
FI940903A0 (fi) 1994-02-25
SG103820A1 (en) 2004-05-26
JP3581821B2 (ja) 2004-10-27
ATE239753T1 (de) 2003-05-15
AU717116B2 (en) 2000-03-16
JP3581802B2 (ja) 2004-10-27
HK1019753A1 (en) 2000-02-25
US5830886A (en) 1998-11-03
NO940635L (fr) 1994-04-29
UA41875C2 (uk) 2001-10-15
NO20044458L (no) 1994-04-29
ES2196483T3 (es) 2003-12-16
RU2182152C2 (ru) 2002-05-10
EP0921130B1 (fr) 2003-05-07
EP0921130A3 (fr) 2001-09-05
SK282188B6 (sk) 2001-12-03
GEP20022802B (en) 2002-09-25
DK0641355T3 (da) 2000-10-09
GEP20033094B (en) 2003-10-27
DE69233053D1 (de) 2003-06-12
GEP20022766B (en) 2002-08-26
FI20050991A (fi) 2005-10-03
DK0921130T3 (da) 2003-07-21
DK0928609T3 (da) 2003-07-21
NO995075D0 (no) 1999-10-18
ATE194843T1 (de) 2000-08-15
SG115508A1 (en) 2005-10-28
ATE237333T1 (de) 2003-05-15
CY2253B1 (en) 2003-07-04
EP0982032A2 (fr) 2000-03-01
GEP20063773B (en) 2006-03-27
SG103374A1 (en) 2004-04-29
JP2000355598A (ja) 2000-12-26
KR100258396B1 (ko) 2000-08-01
SG73391A1 (en) 2006-08-30
NO308774B1 (no) 2000-10-30
ES2148178T3 (es) 2000-10-16
NO995076D0 (no) 1999-10-18
JP2002255993A (ja) 2002-09-11
NO20002595D0 (no) 2000-05-19
AU1007799A (en) 1999-03-04
KR100321019B1 (ko) 2002-03-20
AU5837396A (en) 1996-09-05
DE69233431T2 (de) 2006-02-23
JP3581820B2 (ja) 2004-10-27
AU668882B2 (en) 1996-05-23
DE69233053T2 (de) 2003-11-20
NO318009B1 (no) 2005-01-17
NO2595A (no) 1994-04-29
US5616574A (en) 1997-04-01
SK282189B6 (sk) 2001-12-03
KR100321018B1 (ko) 2002-03-20
DE69233149T2 (de) 2004-06-24
CA2114630A1 (fr) 1993-03-18
GR3034579T3 (en) 2001-01-31
DE69233020T2 (de) 2003-11-06
UA70957C2 (uk) 2004-11-15
SG88782A1 (en) 2002-05-21
JP3219408B2 (ja) 2001-10-15
EP0921130A2 (fr) 1999-06-09
EP0928609A3 (fr) 2001-11-07
ATE246706T1 (de) 2003-08-15
GB9118478D0 (en) 1991-10-16
FI20002260A (fi) 2000-10-13
JP2000355542A (ja) 2000-12-26
US6159960A (en) 2000-12-12
HK1020672A1 (en) 2000-05-19
DE69233149D1 (de) 2003-09-11
EP0928609B1 (fr) 2003-04-16
RU2001125673A (ru) 2003-06-27
JP2003176297A (ja) 2003-06-24
DK0982032T3 (da) 2003-11-03

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