NO822216L - Fremgangsmaate for fremstilling av bromhexin-retardform - Google Patents

Fremgangsmaate for fremstilling av bromhexin-retardform

Info

Publication number
NO822216L
NO822216L NO822216A NO822216A NO822216L NO 822216 L NO822216 L NO 822216L NO 822216 A NO822216 A NO 822216A NO 822216 A NO822216 A NO 822216A NO 822216 L NO822216 L NO 822216L
Authority
NO
Norway
Prior art keywords
bromhexin
preparing
procedure
retard form
retard
Prior art date
Application number
NO822216A
Other languages
English (en)
Other versions
NO159061C (no
NO159061B (no
Inventor
Peter Gruber
Jochen Schmid
Horst Lechner
Eckhart Bauer
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO822216L publication Critical patent/NO822216L/no
Publication of NO159061B publication Critical patent/NO159061B/no
Publication of NO159061C publication Critical patent/NO159061C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO822216A 1981-07-07 1982-06-29 Fremgangsmaate for fremstilling av en bromhexin-retardform. NO159061C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813126703 DE3126703A1 (de) 1981-07-07 1981-07-07 Bromhexin-retardform und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
NO822216L true NO822216L (no) 1983-01-10
NO159061B NO159061B (no) 1988-08-22
NO159061C NO159061C (no) 1988-11-30

Family

ID=6136275

Family Applications (1)

Application Number Title Priority Date Filing Date
NO822216A NO159061C (no) 1981-07-07 1982-06-29 Fremgangsmaate for fremstilling av en bromhexin-retardform.

Country Status (24)

Country Link
US (1) US4438091A (no)
EP (1) EP0069259B1 (no)
JP (1) JPS5859916A (no)
KR (1) KR880001753B1 (no)
AR (1) AR229183A1 (no)
AT (1) ATE11106T1 (no)
AU (1) AU556917B2 (no)
CA (1) CA1205384A (no)
CS (1) CS244909B2 (no)
DE (2) DE3126703A1 (no)
DK (1) DK163171C (no)
ES (1) ES513754A0 (no)
FI (1) FI822375L (no)
GB (1) GB2101485B (no)
GR (1) GR76850B (no)
HU (1) HU186538B (no)
IE (1) IE53803B1 (no)
IL (1) IL66224A (no)
NO (1) NO159061C (no)
NZ (1) NZ201182A (no)
PH (1) PH20651A (no)
PL (1) PL142312B1 (no)
PT (1) PT75198B (no)
ZA (1) ZA824786B (no)

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DE3320582A1 (de) * 1983-06-08 1984-12-13 Dr. Karl Thomae Gmbh, 7950 Biberach Gliquidonhaltige zubereitungsformen und verfahren zu ihrer herstellung
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JP3149125B2 (ja) * 1995-05-01 2001-03-26 信越化学工業株式会社 固形腸溶製剤のコーティング用基剤
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JP2000159692A (ja) * 1998-09-25 2000-06-13 Sankyo Co Ltd HMG―CoAレダクタ―ゼ阻害薬含有製剤
US6319332B1 (en) 1999-06-11 2001-11-20 James Albert Gavney, Jr. Squeegee device and system
JP2003508422A (ja) 1999-09-02 2003-03-04 ノストラム・ファーマスーティカルズ・インコーポレイテッド 放出制御ペレット製剤
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
DE10149674A1 (de) 2001-10-09 2003-04-24 Apogepha Arzneimittel Gmbh Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
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US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
DE10209982A1 (de) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
DE10337697A1 (de) * 2003-08-16 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tablette enthaltend 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenyl-amino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester oder dessen Salze
DE10339862A1 (de) * 2003-08-29 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel
DE10341414A1 (de) * 2003-09-05 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral zu applizierende Darreichungsform für schwerlösliche saure und amphotere Wirkstoffe
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DE102004023930A1 (de) * 2004-05-12 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Schnell lösliches Granulat von Bromhexin/Bromhexinhydrochlorid, Verfahren zu dessen Herstellung und dessen Verwendung
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PL1912650T3 (pl) 2005-08-03 2018-01-31 Sprout Pharmaceuticals Inc Zastosowanie flibanseryny w leczeniu otyłości
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Also Published As

Publication number Publication date
NZ201182A (en) 1985-09-13
HU186538B (en) 1985-08-28
FI822375L (fi) 1983-01-08
DE3126703A1 (de) 1983-01-27
AU8564682A (en) 1983-01-13
PT75198B (de) 1985-10-04
ES8400667A1 (es) 1983-11-01
CS516382A2 (en) 1985-09-17
FI822375A0 (fi) 1982-07-05
IE53803B1 (en) 1989-03-01
JPS5859916A (ja) 1983-04-09
AU556917B2 (en) 1986-11-27
KR840000230A (ko) 1984-02-18
PL142312B1 (en) 1987-10-31
DK303682A (da) 1983-01-08
GR76850B (no) 1984-09-04
EP0069259A3 (en) 1983-06-15
CA1205384A (en) 1986-06-03
AR229183A1 (es) 1983-06-30
EP0069259A2 (de) 1983-01-12
IL66224A0 (en) 1982-11-30
GB2101485A (en) 1983-01-19
IE821626L (en) 1983-01-07
CS244909B2 (en) 1986-08-14
PH20651A (en) 1987-03-16
EP0069259B1 (de) 1985-01-09
PL237305A1 (en) 1985-05-07
US4438091A (en) 1984-03-20
NO159061C (no) 1988-11-30
IL66224A (en) 1986-02-28
ATE11106T1 (de) 1985-01-15
KR880001753B1 (ko) 1988-09-12
ZA824786B (en) 1984-03-28
DK163171C (da) 1992-06-22
ES513754A0 (es) 1983-11-01
PT75198A (de) 1982-08-01
DE3261839D1 (en) 1985-02-21
GB2101485B (en) 1984-10-03
DK163171B (da) 1992-02-03
NO159061B (no) 1988-08-22

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