ZA824786B - Pharmaceutical compositions of bromhexine - Google Patents

Pharmaceutical compositions of bromhexine

Info

Publication number
ZA824786B
ZA824786B ZA824786A ZA824786A ZA824786B ZA 824786 B ZA824786 B ZA 824786B ZA 824786 A ZA824786 A ZA 824786A ZA 824786 A ZA824786 A ZA 824786A ZA 824786 B ZA824786 B ZA 824786B
Authority
ZA
South Africa
Prior art keywords
bromhexine
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
ZA824786A
Other languages
English (en)
Inventor
Peter Dr Gruber
Jochen Dr Schmid
Horst Dr Lechner
Eckhart Dr Bauer
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA824786B publication Critical patent/ZA824786B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA824786A 1981-07-07 1982-07-06 Pharmaceutical compositions of bromhexine ZA824786B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813126703 DE3126703A1 (de) 1981-07-07 1981-07-07 Bromhexin-retardform und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA824786B true ZA824786B (en) 1984-03-28

Family

ID=6136275

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA824786A ZA824786B (en) 1981-07-07 1982-07-06 Pharmaceutical compositions of bromhexine

Country Status (24)

Country Link
US (1) US4438091A (xx)
EP (1) EP0069259B1 (xx)
JP (1) JPS5859916A (xx)
KR (1) KR880001753B1 (xx)
AR (1) AR229183A1 (xx)
AT (1) ATE11106T1 (xx)
AU (1) AU556917B2 (xx)
CA (1) CA1205384A (xx)
CS (1) CS244909B2 (xx)
DE (2) DE3126703A1 (xx)
DK (1) DK163171C (xx)
ES (1) ES513754A0 (xx)
FI (1) FI822375L (xx)
GB (1) GB2101485B (xx)
GR (1) GR76850B (xx)
HU (1) HU186538B (xx)
IE (1) IE53803B1 (xx)
IL (1) IL66224A (xx)
NO (1) NO159061C (xx)
NZ (1) NZ201182A (xx)
PH (1) PH20651A (xx)
PL (1) PL142312B1 (xx)
PT (1) PT75198B (xx)
ZA (1) ZA824786B (xx)

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DE10149674A1 (de) 2001-10-09 2003-04-24 Apogepha Arzneimittel Gmbh Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
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DE10209982A1 (de) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
SG146435A1 (en) * 2002-03-07 2008-10-30 Boehringer Ingelheim Pharma Form of presentation for 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl- amino] propionic acid ethyl ester to be administered orally
DE10337697A1 (de) * 2003-08-16 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tablette enthaltend 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenyl-amino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester oder dessen Salze
DE10339862A1 (de) * 2003-08-29 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel
DE10341414A1 (de) * 2003-09-05 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral zu applizierende Darreichungsform für schwerlösliche saure und amphotere Wirkstoffe
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
DE102004023930A1 (de) * 2004-05-12 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Schnell lösliches Granulat von Bromhexin/Bromhexinhydrochlorid, Verfahren zu dessen Herstellung und dessen Verwendung
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US8679541B2 (en) * 2007-03-14 2014-03-25 Particle Dynamics International, Llc Spatial arrangement of particles in a drinking device for oral delivery of pharmaceuticals
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CN105640909B (zh) 2014-11-14 2019-09-20 正大天晴药业集团股份有限公司 一种含有达比加群酯的药用组合物
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Also Published As

Publication number Publication date
HU186538B (en) 1985-08-28
PT75198A (de) 1982-08-01
AR229183A1 (es) 1983-06-30
NZ201182A (en) 1985-09-13
FI822375A0 (fi) 1982-07-05
PL142312B1 (en) 1987-10-31
DK163171C (da) 1992-06-22
PL237305A1 (en) 1985-05-07
IL66224A0 (en) 1982-11-30
JPS5859916A (ja) 1983-04-09
CS244909B2 (en) 1986-08-14
NO822216L (no) 1983-01-10
ES8400667A1 (es) 1983-11-01
US4438091A (en) 1984-03-20
ES513754A0 (es) 1983-11-01
IE821626L (en) 1983-01-07
DE3261839D1 (en) 1985-02-21
GR76850B (xx) 1984-09-04
CS516382A2 (en) 1985-09-17
DK303682A (da) 1983-01-08
IE53803B1 (en) 1989-03-01
EP0069259B1 (de) 1985-01-09
AU556917B2 (en) 1986-11-27
PH20651A (en) 1987-03-16
KR880001753B1 (ko) 1988-09-12
KR840000230A (ko) 1984-02-18
DK163171B (da) 1992-02-03
EP0069259A3 (en) 1983-06-15
NO159061B (no) 1988-08-22
EP0069259A2 (de) 1983-01-12
CA1205384A (en) 1986-06-03
ATE11106T1 (de) 1985-01-15
PT75198B (de) 1985-10-04
DE3126703A1 (de) 1983-01-27
AU8564682A (en) 1983-01-13
GB2101485A (en) 1983-01-19
NO159061C (no) 1988-11-30
GB2101485B (en) 1984-10-03
FI822375L (fi) 1983-01-08
IL66224A (en) 1986-02-28

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