NO820957L - Fremgangsmaate for fremstilling av nye oxazafosforin-4-tioalkansulfonsyrer og noeytrale salter derav - Google Patents

Fremgangsmaate for fremstilling av nye oxazafosforin-4-tioalkansulfonsyrer og noeytrale salter derav

Info

Publication number
NO820957L
NO820957L NO820957A NO820957A NO820957L NO 820957 L NO820957 L NO 820957L NO 820957 A NO820957 A NO 820957A NO 820957 A NO820957 A NO 820957A NO 820957 L NO820957 L NO 820957L
Authority
NO
Norway
Prior art keywords
tioalcan
phosphorphorin
noeytral
oxaza
salts
Prior art date
Application number
NO820957A
Other languages
English (en)
Other versions
NO163692C (no
NO163692B (no
Inventor
Gerhard Scheffler
Ulf Niemeyer
Norbert Brock
Joerg Pohl
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of NO820957L publication Critical patent/NO820957L/no
Publication of NO163692B publication Critical patent/NO163692B/no
Publication of NO163692C publication Critical patent/NO163692C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO820957A 1981-03-24 1982-03-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive oksazafosforin-4-tio-alkansulfonsyrer og salter derav. NO163692C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813111428 DE3111428A1 (de) 1981-03-24 1981-03-24 Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Publications (3)

Publication Number Publication Date
NO820957L true NO820957L (no) 1982-09-27
NO163692B NO163692B (no) 1990-03-26
NO163692C NO163692C (no) 1990-07-04

Family

ID=6128090

Family Applications (1)

Application Number Title Priority Date Filing Date
NO820957A NO163692C (no) 1981-03-24 1982-03-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive oksazafosforin-4-tio-alkansulfonsyrer og salter derav.

Country Status (31)

Country Link
US (2) US4623742A (no)
JP (1) JPS57169496A (no)
AT (1) AT381317B (no)
AU (1) AU544493B2 (no)
BE (1) BE892589A (no)
BG (1) BG38489A3 (no)
CA (1) CA1194479A (no)
CH (1) CH648852A5 (no)
DD (1) DD201799A5 (no)
DE (1) DE3111428A1 (no)
DK (1) DK171843B1 (no)
EG (1) EG15703A (no)
ES (1) ES510677A0 (no)
FI (1) FI69849C (no)
FR (1) FR2502626B1 (no)
GB (1) GB2095256B (no)
GR (1) GR75533B (no)
HU (1) HU186915B (no)
IE (1) IE53054B1 (no)
IL (1) IL65255A (no)
IT (1) IT1150499B (no)
LU (1) LU84032A1 (no)
NL (1) NL192741C (no)
NO (1) NO163692C (no)
PL (1) PL129426B1 (no)
PT (1) PT74641B (no)
RO (1) RO84661B (no)
SE (1) SE452159B (no)
SU (1) SU1318167A3 (no)
YU (1) YU61582A (no)
ZA (1) ZA821637B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111428A1 (de) 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
EP0083439B1 (de) * 1981-12-31 1989-07-26 ASTA Pharma AG 4-Sulfido-oxazaphosphorine und deren Verwendung bei der Krebsbekämpfung und zur Immunsuppression
DE3569737D1 (en) * 1984-03-01 1989-06-01 Asta Pharma Ag Salts of oxazaphosphorine derivatives
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
DE3415726A1 (de) * 1984-04-27 1985-10-31 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Verfahren zur herstellung von in 4-stellung substituierten oxazaphosphorin-derivaten
FR2567129B1 (fr) * 1984-07-06 1986-12-05 Adir Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5204335A (en) * 1986-10-31 1993-04-20 Asta Pharma Aktiengesellschaft Ifosfamide lyophilisate and process for its preparation
ES2040394T3 (es) * 1988-03-19 1993-10-16 Asta Medica Aktiengesellschaft Procedimiento para preparar un material liofilizado de ifosfamida y mesna.
US5190929A (en) * 1988-05-25 1993-03-02 Research Corporation Technologies, Inc. Cyclophosphamide analogs useful as anti-tumor agents
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
US5661188A (en) * 1995-06-07 1997-08-26 Medical Research Foundation and Infrastructure Development for Health Services--Nahariya Hospital Branch Therapeutic uses for sodium 2-mercaptoethanesulphonate (mesna)
US20080223826A1 (en) * 2007-03-13 2008-09-18 Stephen Mazur Reagent Delivery using a Membrane-Mediated Process
FR2968662B1 (fr) 2010-12-10 2013-11-22 Roussy Inst Gustave Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2107936C3 (de) * 1971-02-19 1978-06-08 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld Alkylsulfonsäureester von 2-Oxo-13,2-oxazaphosphorinanen und diese enthaltende pharmazeutische Präparate
DE1645921C3 (de) * 1966-07-11 1978-10-12 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld 2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE2201675A1 (de) * 1972-01-14 1973-07-19 Asta Werke Ag Chem Fab Alkylsulfonsaeureester 1,3,2-oxazaphospha-cyclischer verbindungen, verfahren zu ihrer herstellung und pharmazeutische praeparate
JPS5159886A (no) * 1974-11-20 1976-05-25 Shionogi Seiyaku Kk
JPS54157580A (en) 1978-05-29 1979-12-12 Otsuka Pharmaceut Co Ltd Optically active oxazaphosphorine derivative
JPS5826919B2 (ja) 1978-11-07 1983-06-06 大塚製薬株式会社 シクロ↓−１，３，２↓−オキサアザホスホル誘導体の製造法
JPS55154984A (en) * 1979-05-24 1980-12-02 Shionogi & Co Ltd Novel 4-substituted-2h-1,3,2-oxaazaphospholine-2-oxide derivative
DE3111428A1 (de) 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3220672A1 (de) 1981-03-24 1983-12-08 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Cis-oxazaphosphorin-4-thio-alkansulfonsaeuren, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3220432A1 (de) 1981-03-24 1983-12-01 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeure, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate

Also Published As

Publication number Publication date
JPH0240680B2 (no) 1990-09-12
FI821021A0 (fi) 1982-03-23
CH648852A5 (de) 1985-04-15
NO163692C (no) 1990-07-04
ATA106382A (de) 1986-02-15
FR2502626B1 (fr) 1986-01-03
BG38489A3 (en) 1985-12-16
ES8303440A1 (es) 1983-02-01
PT74641A (de) 1982-04-01
PT74641B (de) 1983-10-20
HU186915B (en) 1985-10-28
US4929607A (en) 1990-05-29
NL192741C (nl) 1998-01-06
LU84032A1 (de) 1982-07-08
IT8220351A0 (it) 1982-03-23
RO84661A (ro) 1984-10-31
AT381317B (de) 1986-09-25
IE53054B1 (en) 1988-05-25
YU61582A (en) 1985-03-20
PL129426B1 (en) 1984-05-31
IT1150499B (it) 1986-12-10
AU544493B2 (en) 1985-05-30
IE820531L (en) 1982-09-24
DE3111428A1 (de) 1982-10-07
NO163692B (no) 1990-03-26
FR2502626A1 (fr) 1982-10-01
ES510677A0 (es) 1983-02-01
FI69849B (fi) 1985-12-31
US4623742A (en) 1986-11-18
GR75533B (no) 1984-07-27
DK129882A (da) 1982-09-25
SU1318167A3 (ru) 1987-06-15
DD201799A5 (de) 1983-08-10
FI821021L (fi) 1982-09-25
NL8201227A (nl) 1982-10-18
GB2095256A (en) 1982-09-29
IL65255A0 (en) 1982-05-31
NL192741B (nl) 1997-09-01
SE452159B (sv) 1987-11-16
PL235606A1 (no) 1982-11-08
GB2095256B (en) 1984-08-22
DK171843B1 (da) 1997-06-30
SE8201807L (sv) 1982-09-25
FI69849C (fi) 1986-05-26
RO84661B (ro) 1984-11-30
BE892589A (fr) 1982-07-16
CA1194479A (en) 1985-10-01
EG15703A (en) 1986-06-30
JPS57169496A (en) 1982-10-19
IL65255A (en) 1986-03-31
ZA821637B (en) 1983-02-23
DE3111428C2 (no) 1990-06-13
AU8134482A (en) 1982-09-30

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Free format text: EXPIRED IN MARCH 2002