NO864818D0 - Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater. - Google Patents

Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater.

Info

Publication number
NO864818D0
NO864818D0 NO864818A NO864818A NO864818D0 NO 864818 D0 NO864818 D0 NO 864818D0 NO 864818 A NO864818 A NO 864818A NO 864818 A NO864818 A NO 864818A NO 864818 D0 NO864818 D0 NO 864818D0
Authority
NO
Norway
Prior art keywords
tetrahydroisokinolin
derivatives
procedure
preparation
therapeutically effective
Prior art date
Application number
NO864818A
Other languages
English (en)
Other versions
NO864818L (no
Inventor
Robin D Clark
Joseph M Muchowski
Fang-Ting Chiu
John O Gardner
Jacob Berger
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/803,464 external-priority patent/US4613606A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO864818D0 publication Critical patent/NO864818D0/no
Publication of NO864818L publication Critical patent/NO864818L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO864818A 1985-12-02 1986-12-01 Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater. NO864818L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/803,464 US4613606A (en) 1985-12-02 1985-12-02 Tetrahydroisoquinoline derivatives
US06/909,659 US4667038A (en) 1985-12-02 1986-09-22 Tetrahydroisoquinoline derivatives

Publications (2)

Publication Number Publication Date
NO864818D0 true NO864818D0 (no) 1986-12-01
NO864818L NO864818L (no) 1987-06-03

Family

ID=27122597

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864818A NO864818L (no) 1985-12-02 1986-12-01 Fremgangsmaate for fremstilling av nye terapeutisk virksomme tetrahydroisokinolinderivater.

Country Status (11)

Country Link
US (1) US4667038A (no)
EP (1) EP0229944A3 (no)
KR (1) KR900000672B1 (no)
CN (1) CN86108089A (no)
AU (2) AU598772B2 (no)
DK (1) DK576986A (no)
FI (1) FI864893A (no)
HU (1) HU197312B (no)
IL (1) IL80824A0 (no)
NO (1) NO864818L (no)
PL (1) PL262734A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69524962T4 (de) * 1994-08-22 2003-08-28 Mitsubishi Pharma Corp., Osaka Benzolderivate und deren medizinische verwendung
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
PT1471054E (pt) 2002-01-11 2009-09-23 Daiichi Sankyo Co Ltd Derivado de aminoálcool ou derivado de ácido fosfónico e composição medicinal que os contém
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물
KR100870576B1 (ko) * 2008-08-27 2008-11-27 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는 7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린 유도체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1154810B (de) * 1961-04-01 1963-09-26 Knoll Ag Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
DE1802804A1 (de) * 1968-10-12 1970-06-11 Knoll Ag 1-[3'-Cyan-3'-(2'',3''-dimethoxyphenyl)-4'-methylpentyl]-2-methyl-6,7-dimethoxy-1,2,3,4-Tetrahydroisochinolin
US4613606A (en) * 1985-12-02 1986-09-23 Syntex (U.S.A.) Inc. Tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
US4667038A (en) 1987-05-19
PL262734A1 (en) 1988-07-21
KR900000672B1 (ko) 1990-02-02
NO864818L (no) 1987-06-03
KR870006042A (ko) 1987-07-08
DK576986A (da) 1987-06-03
HU197312B (en) 1989-03-28
CN86108089A (zh) 1987-09-16
FI864893A0 (fi) 1986-12-01
AU5363090A (en) 1990-09-13
AU6584986A (en) 1987-06-04
FI864893A (fi) 1987-06-03
EP0229944A3 (en) 1987-10-21
EP0229944A2 (en) 1987-07-29
IL80824A0 (en) 1987-03-31
DK576986D0 (da) 1986-12-01
AU598772B2 (en) 1990-07-05
HUT43043A (en) 1987-09-28

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