IL80824A0 - Tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL80824A0
IL80824A0 IL80824A IL8082486A IL80824A0 IL 80824 A0 IL80824 A0 IL 80824A0 IL 80824 A IL80824 A IL 80824A IL 8082486 A IL8082486 A IL 8082486A IL 80824 A0 IL80824 A0 IL 80824A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
tetrahydroisoquinoline derivatives
tetrahydroisoquinoline
Prior art date
Application number
IL80824A
Other languages
English (en)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/803,464 external-priority patent/US4613606A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IL80824A0 publication Critical patent/IL80824A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL80824A 1985-12-02 1986-12-01 Tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them IL80824A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/803,464 US4613606A (en) 1985-12-02 1985-12-02 Tetrahydroisoquinoline derivatives
US06/909,659 US4667038A (en) 1985-12-02 1986-09-22 Tetrahydroisoquinoline derivatives

Publications (1)

Publication Number Publication Date
IL80824A0 true IL80824A0 (en) 1987-03-31

Family

ID=27122597

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80824A IL80824A0 (en) 1985-12-02 1986-12-01 Tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them

Country Status (11)

Country Link
US (1) US4667038A (no)
EP (1) EP0229944A3 (no)
KR (1) KR900000672B1 (no)
CN (1) CN86108089A (no)
AU (2) AU598772B2 (no)
DK (1) DK576986A (no)
FI (1) FI864893A (no)
HU (1) HU197312B (no)
IL (1) IL80824A0 (no)
NO (1) NO864818L (no)
PL (1) PL262734A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100358922B1 (ko) * 1994-08-22 2003-01-24 미쯔비시 웰 파마 가부시키가이샤 벤젠화합물및그의의약으로서의용도
US5948820A (en) * 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
WO2003059880A1 (fr) 2002-01-11 2003-07-24 Sankyo Company, Limited Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant
CN1921847B (zh) 2004-02-24 2010-06-16 三共株式会社 氨基醇化合物
KR100870576B1 (ko) * 2008-08-27 2008-11-27 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는 7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린 유도체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1154810B (de) * 1961-04-01 1963-09-26 Knoll Ag Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
DE1802804A1 (de) * 1968-10-12 1970-06-11 Knoll Ag 1-[3'-Cyan-3'-(2'',3''-dimethoxyphenyl)-4'-methylpentyl]-2-methyl-6,7-dimethoxy-1,2,3,4-Tetrahydroisochinolin
US4613606A (en) * 1985-12-02 1986-09-23 Syntex (U.S.A.) Inc. Tetrahydroisoquinoline derivatives

Also Published As

Publication number Publication date
DK576986A (da) 1987-06-03
HUT43043A (en) 1987-09-28
PL262734A1 (en) 1988-07-21
EP0229944A2 (en) 1987-07-29
HU197312B (en) 1989-03-28
FI864893A0 (fi) 1986-12-01
CN86108089A (zh) 1987-09-16
NO864818L (no) 1987-06-03
NO864818D0 (no) 1986-12-01
AU5363090A (en) 1990-09-13
FI864893A (fi) 1987-06-03
KR870006042A (ko) 1987-07-08
KR900000672B1 (ko) 1990-02-02
US4667038A (en) 1987-05-19
AU6584986A (en) 1987-06-04
EP0229944A3 (en) 1987-10-21
DK576986D0 (da) 1986-12-01
AU598772B2 (en) 1990-07-05

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