NO320380B1 - Fremgangsmate for fremstilling av vedvarende frigivelsespartikler - Google Patents
Fremgangsmate for fremstilling av vedvarende frigivelsespartikler Download PDFInfo
- Publication number
- NO320380B1 NO320380B1 NO19971965A NO971965A NO320380B1 NO 320380 B1 NO320380 B1 NO 320380B1 NO 19971965 A NO19971965 A NO 19971965A NO 971965 A NO971965 A NO 971965A NO 320380 B1 NO320380 B1 NO 320380B1
- Authority
- NO
- Norway
- Prior art keywords
- diluent
- carrier
- fusible
- optionally
- soluble
- Prior art date
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- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 description 1
- 229960003320 roxatidine Drugs 0.000 description 1
- 229960002052 salbutamol Drugs 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229960002370 sotalol Drugs 0.000 description 1
- ZBMZVLHSJCTVON-UHFFFAOYSA-N sotalol Chemical compound CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1 ZBMZVLHSJCTVON-UHFFFAOYSA-N 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- GGCSSNBKKAUURC-UHFFFAOYSA-N sufentanil Chemical compound C1CN(CCC=2SC=CC=2)CCC1(COC)N(C(=O)CC)C1=CC=CC=C1 GGCSSNBKKAUURC-UHFFFAOYSA-N 0.000 description 1
- 229960004739 sufentanil Drugs 0.000 description 1
- 229960000468 sulfalene Drugs 0.000 description 1
- KXRZBTAEDBELFD-UHFFFAOYSA-N sulfamethopyrazine Chemical compound COC1=NC=CN=C1NS(=O)(=O)C1=CC=C(N)C=C1 KXRZBTAEDBELFD-UHFFFAOYSA-N 0.000 description 1
- 229960004940 sulpiride Drugs 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229960002871 tenoxicam Drugs 0.000 description 1
- LZNWYQJJBLGYLT-UHFFFAOYSA-N tenoxicam Chemical compound OC=1C=2SC=CC=2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 LZNWYQJJBLGYLT-UHFFFAOYSA-N 0.000 description 1
- VCKUSRYTPJJLNI-UHFFFAOYSA-N terazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1CCCO1 VCKUSRYTPJJLNI-UHFFFAOYSA-N 0.000 description 1
- 229960001693 terazosin Drugs 0.000 description 1
- 229960000195 terbutaline Drugs 0.000 description 1
- 229960000351 terfenadine Drugs 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 150000007970 thio esters Chemical class 0.000 description 1
- MNRILEROXIRVNJ-UHFFFAOYSA-N tioguanine Chemical compound N1C(N)=NC(=S)C2=NC=N[C]21 MNRILEROXIRVNJ-UHFFFAOYSA-N 0.000 description 1
- 229960003087 tioguanine Drugs 0.000 description 1
- 229960005013 tiotixene Drugs 0.000 description 1
- 229960002872 tocainide Drugs 0.000 description 1
- 229960002277 tolazamide Drugs 0.000 description 1
- OUDSBRTVNLOZBN-UHFFFAOYSA-N tolazamide Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)NN1CCCCCC1 OUDSBRTVNLOZBN-UHFFFAOYSA-N 0.000 description 1
- LLPOLZWFYMWNKH-UHFFFAOYSA-N trans-dihydrocodeinone Natural products C1C(N(CCC234)C)C2CCC(=O)C3OC2=C4C1=CC=C2OC LLPOLZWFYMWNKH-UHFFFAOYSA-N 0.000 description 1
- PHLBKPHSAVXXEF-UHFFFAOYSA-N trazodone Chemical compound ClC1=CC=CC(N2CCN(CCCN3C(N4C=CC=CC4=N3)=O)CC2)=C1 PHLBKPHSAVXXEF-UHFFFAOYSA-N 0.000 description 1
- 229960003991 trazodone Drugs 0.000 description 1
- ZEWQUBUPAILYHI-UHFFFAOYSA-N trifluoperazine Chemical compound C1CN(C)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 ZEWQUBUPAILYHI-UHFFFAOYSA-N 0.000 description 1
- 229960002324 trifluoperazine Drugs 0.000 description 1
- XSCGXQMFQXDFCW-UHFFFAOYSA-N triflupromazine Chemical compound C1=C(C(F)(F)F)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 XSCGXQMFQXDFCW-UHFFFAOYSA-N 0.000 description 1
- 229960003904 triflupromazine Drugs 0.000 description 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
- 229960001082 trimethoprim Drugs 0.000 description 1
- 229960001128 triprolidine Drugs 0.000 description 1
- CBEQULMOCCWAQT-WOJGMQOQSA-N triprolidine Chemical compound C1=CC(C)=CC=C1C(\C=1N=CC=CC=1)=C/CN1CCCC1 CBEQULMOCCWAQT-WOJGMQOQSA-N 0.000 description 1
- IRGJVQIJENCTQF-UHFFFAOYSA-N tritoqualine Chemical compound CN1CCC2=CC=3OCOC=3C(OC)=C2C1C1C2=C(OCC)C(OCC)=C(OCC)C(N)=C2C(=O)O1 IRGJVQIJENCTQF-UHFFFAOYSA-N 0.000 description 1
- UMKFEPPTGMDVMI-UHFFFAOYSA-N trofosfamide Chemical compound ClCCN(CCCl)P1(=O)OCCCN1CCCl UMKFEPPTGMDVMI-UHFFFAOYSA-N 0.000 description 1
- 229960000875 trofosfamide Drugs 0.000 description 1
- 229960001130 urapidil Drugs 0.000 description 1
- 229960001722 verapamil Drugs 0.000 description 1
- 229960001255 viloxazine Drugs 0.000 description 1
- DKRSEIPLAZTSFD-LSDHHAIUSA-N viquidil Chemical compound C12=CC(OC)=CC=C2N=CC=C1C(=O)CC[C@@H]1CCNC[C@@H]1C=C DKRSEIPLAZTSFD-LSDHHAIUSA-N 0.000 description 1
- 229960003353 viquidil Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Glanulating (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9422154A GB9422154D0 (en) | 1994-11-03 | 1994-11-03 | Pharmaceutical compositions and method of producing the same |
PCT/GB1995/002579 WO1996014059A1 (en) | 1994-11-03 | 1995-11-03 | Pharmaceutical composition containing a fusible carrier and method for producing the same |
Publications (3)
Publication Number | Publication Date |
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NO971965D0 NO971965D0 (no) | 1997-04-28 |
NO971965L NO971965L (no) | 1997-04-28 |
NO320380B1 true NO320380B1 (no) | 2005-11-28 |
Family
ID=10763811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19971965A NO320380B1 (no) | 1994-11-03 | 1997-04-28 | Fremgangsmate for fremstilling av vedvarende frigivelsespartikler |
Country Status (17)
Country | Link |
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US (1) | US6068855A (fi) |
EP (1) | EP0789559B2 (fi) |
JP (2) | JP3504953B2 (fi) |
KR (1) | KR100413581B1 (fi) |
AT (1) | ATE179886T1 (fi) |
AU (1) | AU3811095A (fi) |
DE (1) | DE69509671T3 (fi) |
DK (1) | DK0789559T4 (fi) |
ES (1) | ES2134501T5 (fi) |
FI (1) | FI114780B (fi) |
GB (1) | GB9422154D0 (fi) |
GR (1) | GR3030938T3 (fi) |
NO (1) | NO320380B1 (fi) |
NZ (1) | NZ294897A (fi) |
TW (1) | TW348062B (fi) |
WO (1) | WO1996014059A1 (fi) |
ZA (1) | ZA959308B (fi) |
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US6548084B2 (en) | 1995-07-20 | 2003-04-15 | Smithkline Beecham Plc | Controlled release compositions |
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RS50070B (sr) | 1997-12-22 | 2009-01-22 | Euro-Celtique S.A., | Oralni dozni oblik sa kombinacijom opijatnog agonista i antagonista |
EP1041988A4 (en) * | 1997-12-22 | 2002-03-13 | Euro Celtique Sa | METHOD FOR PREVENTING ABUSE OF OPIOID DOSES FORMS |
FR2775593B1 (fr) | 1998-03-09 | 2002-06-14 | Oreal | Composition filmogene comprenant un polyurethane en dispersion aqueuse et un agent plastifiant |
GB9817662D0 (en) | 1998-08-13 | 1998-10-07 | Crocker Peter J | Substance delivery |
DE19901692C2 (de) | 1999-01-18 | 2002-06-20 | Gruenenthal Gmbh | Verfahren zur Herstellung von Pellets mit einem Gehalt von bis zu 90 Gew.% eines pharmazeutischen Wirkstoffes |
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JP4480206B2 (ja) * | 1999-08-10 | 2010-06-16 | 大日本住友製薬株式会社 | 油脂含有徐放性坐剤 |
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DE60232417D1 (de) | 2001-08-06 | 2009-07-02 | Euro Celtique Sa | Opioid-agonist-formulierungen mit freisetzbarem und sequestriertem antagonist |
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US5567439A (en) | 1994-06-14 | 1996-10-22 | Fuisz Technologies Ltd. | Delivery of controlled-release systems(s) |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
-
1994
- 1994-11-03 GB GB9422154A patent/GB9422154D0/en active Pending
-
1995
- 1995-11-03 AU AU38110/95A patent/AU3811095A/en not_active Abandoned
- 1995-11-03 US US08/817,956 patent/US6068855A/en not_active Expired - Lifetime
- 1995-11-03 ES ES95936019T patent/ES2134501T5/es not_active Expired - Lifetime
- 1995-11-03 ZA ZA959308A patent/ZA959308B/xx unknown
- 1995-11-03 JP JP51513496A patent/JP3504953B2/ja not_active Expired - Lifetime
- 1995-11-03 WO PCT/GB1995/002579 patent/WO1996014059A1/en active IP Right Grant
- 1995-11-03 KR KR1019970702810A patent/KR100413581B1/ko not_active IP Right Cessation
- 1995-11-03 NZ NZ294897A patent/NZ294897A/xx not_active IP Right Cessation
- 1995-11-03 TW TW084111629A patent/TW348062B/zh not_active IP Right Cessation
- 1995-11-03 AT AT95936019T patent/ATE179886T1/de active
- 1995-11-03 DK DK95936019T patent/DK0789559T4/da active
- 1995-11-03 DE DE69509671T patent/DE69509671T3/de not_active Expired - Lifetime
- 1995-11-03 EP EP95936019A patent/EP0789559B2/en not_active Expired - Lifetime
-
1997
- 1997-04-28 NO NO19971965A patent/NO320380B1/no not_active IP Right Cessation
- 1997-05-02 FI FI971880A patent/FI114780B/fi not_active IP Right Cessation
-
1999
- 1999-08-10 GR GR990402019T patent/GR3030938T3/el unknown
-
2003
- 2003-08-12 JP JP2003292426A patent/JP2004043485A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0789559A1 (en) | 1997-08-20 |
FI971880A (fi) | 1997-06-18 |
JPH10508597A (ja) | 1998-08-25 |
ZA959308B (en) | 1996-05-29 |
DK0789559T4 (da) | 2002-11-25 |
KR100413581B1 (ko) | 2004-03-31 |
ES2134501T5 (es) | 2003-05-01 |
ES2134501T3 (es) | 1999-10-01 |
JP3504953B2 (ja) | 2004-03-08 |
DE69509671T2 (de) | 2000-01-27 |
DK0789559T3 (da) | 1999-11-15 |
JP2004043485A (ja) | 2004-02-12 |
EP0789559B2 (en) | 2002-10-16 |
GR3030938T3 (en) | 1999-11-30 |
WO1996014059A1 (en) | 1996-05-17 |
NO971965D0 (no) | 1997-04-28 |
GB9422154D0 (en) | 1994-12-21 |
KR970706801A (ko) | 1997-12-01 |
FI971880A0 (fi) | 1997-05-02 |
US6068855A (en) | 2000-05-30 |
AU3811095A (en) | 1996-05-31 |
EP0789559B1 (en) | 1999-05-12 |
NZ294897A (en) | 1998-10-28 |
DE69509671D1 (de) | 1999-06-17 |
FI114780B (fi) | 2004-12-31 |
ATE179886T1 (de) | 1999-05-15 |
NO971965L (no) | 1997-04-28 |
DE69509671T3 (de) | 2003-07-31 |
TW348062B (en) | 1998-12-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |