IT1245891B - Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali. - Google Patents

Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Info

Publication number
IT1245891B
IT1245891B ITBO910114A IT1245891B IT 1245891 B IT1245891 B IT 1245891B IT BO910114 A ITBO910114 A IT BO910114A IT 1245891 B IT1245891 B IT 1245891B
Authority
IT
Italy
Prior art keywords
gastroresistant
containing
gastro
salts
controlled release
Prior art date
Application number
Other languages
English (en)
Inventor
Egidio Marchi
Gianfranco Tamagnone
Leone Gabriele Rotini
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Priority to ITBO910114 priority Critical patent/IT1245891B/it
Publication of ITBO910114D0 publication Critical patent/ITBO910114D0/it
Publication of ITBO910114A1 publication Critical patent/ITBO910114A1/it
Application granted granted Critical
Publication of IT1245891B publication Critical patent/IT1245891B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells

Abstract

Formulazioni farmaceutiche a rilascio controllato per uso orale ricoperte da una pellicola gastroresistente enterosolubile, preferibilmente scelte tra granulati gastroresistenti, compresse gastroresistenti, capsule gastroresistenti di gelatina dura contenenti polveri o granulati o due o più compresse o sospensioni oleose, capsule gastroresistenti di gelatina molle contenenti sospensioni oleose e capsule di gelatina dura contenenti granulati gastroresistenti o due o più compresse gastroresistenti, contenenti quantità terapeuticamente efficaci di una miscela di acidi biliari e di loro sali con metalli alcalini o con basi organiche, processo per la loro preparazione e loro uso terapeutico nel trattamento delle calcolosi biliari, delle dispepsie biliari, della cirrosi biliare e delle epatopatie croniche e colestatiche.
ITBO910114 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali. IT1245891B (it)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ITBO910114 IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
ITBO910114 IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.
US07/861,462 US5300300A (en) 1991-04-12 1992-04-01 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts
DE1992613800 DE69213800T2 (de) 1991-04-12 1992-04-02 Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze
TW81102518A TW215899B (it) 1991-04-12 1992-04-02
ES92105717T ES2091970T3 (es) 1991-04-12 1992-04-02 Formulaciones farmaceuticas gastrorresistentes de liberacion controlada para administracion oral que contienen acidos biliares y sus sales.
DE1992613800 DE69213800D1 (de) 1991-04-12 1992-04-02 Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze
EP19920105717 EP0508312B1 (en) 1991-04-12 1992-04-02 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts
CA 2065652 CA2065652C (en) 1991-04-12 1992-04-10 Controlled release gastroresistant pharmaceutical formulations for oral administration containing bile acids and their salts
JP9113192A JP2509046B2 (ja) 1991-04-12 1992-04-10 胆汁酸およびその塩を含有する経口投与用の放出制御型胃液耐性製剤
KR92006053A KR970005177B1 (ko) 1991-04-12 1992-04-11 담즙산과 그 염을 함유하는 경구용 방출제어 위내성 위약 의약 포뮬레이션

Publications (3)

Publication Number Publication Date
ITBO910114D0 ITBO910114D0 (it) 1991-04-12
ITBO910114A1 ITBO910114A1 (it) 1992-10-13
IT1245891B true IT1245891B (it) 1994-10-25

Family

ID=11337392

Family Applications (1)

Application Number Title Priority Date Filing Date
ITBO910114 IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Country Status (9)

Country Link
US (1) US5300300A (it)
EP (1) EP0508312B1 (it)
JP (1) JP2509046B2 (it)
KR (1) KR970005177B1 (it)
CA (1) CA2065652C (it)
DE (2) DE69213800T2 (it)
ES (1) ES2091970T3 (it)
IT (1) IT1245891B (it)
TW (1) TW215899B (it)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
IT1255968B (it) * 1992-11-27 1995-11-17 Composizioni farmaceutiche contenenti acido ursodesossicolico
IL119660A (en) 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5849240A (en) * 1993-11-23 1998-12-15 Euro-Celtique, S.A. Method of preparing sustained release pharmaceutical compositions
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE29717252U1 (de) * 1997-09-26 1998-02-19 Falk Pharma Gmbh Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
US7303768B2 (en) * 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
AU758679B2 (en) 1998-07-24 2003-03-27 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
US20050158408A1 (en) * 1998-07-24 2005-07-21 Yoo Seo H. Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
JP2004500378A (ja) * 2000-02-04 2004-01-08 ヨー、セオ、ホン 胆汁酸を含有する清浄水溶液製型の製造
US6821931B2 (en) * 2002-03-05 2004-11-23 Alpine Mud Products Corporation Water-based drilling fluid additive containing talc and carrier
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
US7145125B2 (en) * 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
US20070015796A1 (en) * 2003-09-26 2007-01-18 Smithkline Beecham Corporation Compositions and methods for treatment of fibrosis
US20050181047A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
CN101035541B (zh) * 2004-08-30 2012-05-30 柳署弘 溶解的udca在局灶缺血模型中的神经保护作用
AU2005295541B2 (en) * 2004-10-15 2011-02-17 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US7772220B2 (en) * 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
JP2008518935A (ja) * 2004-11-01 2008-06-05 ユー セオ ホンYOO Seo Hong 筋萎縮性側索硬化症の神経退行を減少させるための方法及び組成物
WO2006127879A1 (en) * 2005-05-26 2006-11-30 Duramed Pharmaceuticals, Inc. Flexible solid dosage forms and methods of making and using the same
EP2478895A3 (en) * 2006-12-22 2012-12-19 Ironwood Pharmaceuticals, Inc. Compositions for treating esophageal disorders
KR101636958B1 (ko) * 2009-09-11 2016-07-06 주식회사 대웅제약 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법
CA2851765C (en) 2011-10-11 2017-08-15 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof
US20170119680A1 (en) 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2340060A1 (de) * 1973-08-08 1975-02-20 Scherer Gmbh R P Magensaftresistente gelatinekapseln und verfahren zu deren herstellung
IT1101649B (it) 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
IT1212141B (it) 1987-06-03 1989-11-08 So Ri Far S R L Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare.

Also Published As

Publication number Publication date
ITBO910114A1 (it) 1992-10-13
ITBO910114D0 (it) 1991-04-12
US5300300A (en) 1994-04-05
KR970005177B1 (ko) 1997-04-14
DE69213800D1 (de) 1996-10-24
DE69213800T2 (de) 1997-02-20
ES2091970T3 (es) 1996-11-16
EP0508312A1 (en) 1992-10-14
JPH0597677A (ja) 1993-04-20
CA2065652C (en) 1999-01-12
JP2509046B2 (ja) 1996-06-19
CA2065652A1 (en) 1992-10-13
TW215899B (it) 1993-11-11
EP0508312B1 (en) 1996-09-18

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TA Fee payment date (situation as of prs-date), data collected since 19931001

Effective date: 19970423