ATE107854T1 - Pharmazeutisches granulat. - Google Patents

Pharmazeutisches granulat.

Info

Publication number
ATE107854T1
ATE107854T1 AT89309867T AT89309867T ATE107854T1 AT E107854 T1 ATE107854 T1 AT E107854T1 AT 89309867 T AT89309867 T AT 89309867T AT 89309867 T AT89309867 T AT 89309867T AT E107854 T1 ATE107854 T1 AT E107854T1
Authority
AT
Austria
Prior art keywords
pharmaceutical
particulate
granules
spray
pharmaceutically acceptable
Prior art date
Application number
AT89309867T
Other languages
English (en)
Inventor
Tarlok Singh Bola
Original Assignee
Rhone Poulenc Rorer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888823082A external-priority patent/GB8823082D0/en
Priority claimed from GB898907658A external-priority patent/GB8907658D0/en
Application filed by Rhone Poulenc Rorer Ltd filed Critical Rhone Poulenc Rorer Ltd
Application granted granted Critical
Publication of ATE107854T1 publication Critical patent/ATE107854T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
AT89309867T 1988-09-30 1989-09-28 Pharmazeutisches granulat. ATE107854T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888823082A GB8823082D0 (en) 1988-09-30 1988-09-30 New compositions of matter
GB898907658A GB8907658D0 (en) 1989-04-05 1989-04-05 New compositions of matter

Publications (1)

Publication Number Publication Date
ATE107854T1 true ATE107854T1 (de) 1994-07-15

Family

ID=26294465

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89309867T ATE107854T1 (de) 1988-09-30 1989-09-28 Pharmazeutisches granulat.

Country Status (16)

Country Link
US (1) US5489439A (de)
EP (1) EP0361910B1 (de)
JP (1) JPH02180813A (de)
AT (1) ATE107854T1 (de)
AU (1) AU623177B2 (de)
DE (1) DE68916497T2 (de)
DK (1) DK481689A (de)
ES (1) ES2058546T3 (de)
FI (1) FI894611A (de)
HU (1) HU203967B (de)
IE (1) IE63875B1 (de)
IL (1) IL91836A (de)
NO (1) NO893893L (de)
NZ (1) NZ230836A (de)
PT (1) PT91857B (de)
YU (1) YU189289A (de)

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JP2941081B2 (ja) * 1991-03-26 1999-08-25 株式会社奈良機械製作所 結晶性有機化合物の非晶質割合の増加と再結晶化を抑制する方法
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
JP3761649B2 (ja) * 1996-12-11 2006-03-29 住友化学株式会社 粒状農薬組成物の製造方法
DE19705538C1 (de) * 1997-02-14 1998-08-27 Goedecke Ag Verfahren zur Trennung von Wirkstoffen in festen pharmazeutischen Zubereitungen
US6197347B1 (en) 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
EP1005863A1 (de) * 1998-12-04 2000-06-07 Synthelabo Dosisformen mit gesteuerter Wirkstofffreigabe enthaltend ein kurzer wirkung Hypnotikum oder einem Salz davon
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
EP1064937A1 (de) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmazeutische Zusammensetzungen mit kontrollierten Freigabe enthaltend ein Hypnotikum mit kurzer Wirkung oder deren Salze
EP2295043A1 (de) 1999-10-29 2011-03-16 Euro-Celtique S.A. Hydrocodon-Formulierungen mit gesteuerter Freisetzung
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR101167465B1 (ko) 2000-10-30 2012-07-27 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
MY148466A (en) * 2001-10-26 2013-04-30 Merck Frosst Canada Ltd Granule formulation
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
AU2003246792B2 (en) 2002-04-09 2008-08-28 Flamel Ireland Limited Oral suspension of active principle microcapsules
US8992980B2 (en) * 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
KR100466637B1 (ko) * 2003-06-26 2005-01-13 주식회사 펩트론 서방성 미립구의 혼합 제형을 연속한 단일 공정으로제조하는 방법
EP1568369A1 (de) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam zur Behandlung von Atemwegserkrankungen bei Schweinen
EP1830814B1 (de) * 2005-01-06 2009-07-01 Cima Labs Inc. Geschmacksunterdrückungssystem für nicht geweichte arzneimittel
AU2006239838A1 (en) * 2005-04-25 2006-11-02 Teva Pharmaceuticals Usa, Inc. Extended release formulations
US9023400B2 (en) * 2006-05-24 2015-05-05 Flamel Technologies Prolonged-release multimicroparticulate oral pharmaceutical form
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
WO2008011596A2 (en) * 2006-07-21 2008-01-24 Lab International Srl Hydrophilic abuse deterrent delivery system
EP1972336A1 (de) * 2007-03-19 2008-09-24 LEK Pharmaceuticals D.D. Heißschmelz-Mikropellets
ATE515259T1 (de) * 2007-05-29 2011-07-15 Lek Pharmaceuticals Pharmazeutische zusammensetzung mit eszopiclon
ES2588429T3 (es) 2009-03-09 2016-11-02 Spi Pharma, Inc. Excipientes y sistemas de excipientes de compresión directa altamente compactables y durables
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
ME02874B (de) 2010-12-22 2018-04-20 Purdue Pharma Lp Gekapselte manipulationssichere Darreichungsformen mit gesteuerter Freisetzung
AU2011346758C1 (en) 2010-12-23 2015-09-03 Purdue Pharma L.P. Tamper resistant solid oral dosage forms
JP6255908B2 (ja) * 2012-11-09 2018-01-10 大正製薬株式会社 固形製剤
BR112015017451B1 (pt) 2013-02-05 2023-01-10 Purdue Pharma L.P. Formulações farmacêuticas resistentes à violação
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2793979A (en) * 1953-03-30 1957-05-28 Smith Kline French Lab Method of making a sustained release pharmaceutical tablet and product of the method
DE2028224A1 (de) * 1969-06-10 1970-12-17 Solco Basel AG, Basel (Schweiz)j Oral anwendbare Arzneimittelform
GB1509979A (en) * 1975-11-28 1978-05-10 Fisons Ltd Pharmaceutical compositions containing aspirin or indomethacin
EP0094116A3 (de) * 1982-05-06 1984-08-01 The Procter & Gamble Company Therapeutische Granulate
US4743247A (en) * 1984-08-13 1988-05-10 Alza Corporation Process for manufacturing dosage form
AT385654B (de) * 1984-09-04 1988-05-10 Arcana Chem Pharm Verfahren zur herstellung von oelhaeltigen zubereitungen in granulatform zur oralen verabreichung
EP0192321A3 (de) * 1985-01-19 1987-09-02 Beecham Group Plc Allergene enthaltende Arzneimittel mit magensaftresistentem Überzug
DE3681348D1 (de) * 1985-06-11 1991-10-17 Teijin Ltd Oral-arzneizubereitung mit retardwirkung.

Also Published As

Publication number Publication date
AU623177B2 (en) 1992-05-07
JPH02180813A (ja) 1990-07-13
IL91836A0 (en) 1990-06-10
IL91836A (en) 1994-12-29
HU203967B (en) 1991-11-28
AU4241689A (en) 1990-04-05
PT91857A (pt) 1990-03-30
NZ230836A (en) 1990-07-26
DK481689D0 (da) 1989-09-29
NO893893D0 (no) 1989-09-29
DE68916497D1 (de) 1994-08-04
HUT53282A (en) 1990-10-28
IE63875B1 (en) 1995-06-14
YU189289A (en) 1991-04-30
FI894611A0 (fi) 1989-09-28
FI894611A (fi) 1990-03-31
PT91857B (pt) 1995-07-03
EP0361910A1 (de) 1990-04-04
ES2058546T3 (es) 1994-11-01
NO893893L (no) 1990-04-02
US5489439A (en) 1996-02-06
IE893132L (en) 1990-03-30
DE68916497T2 (de) 1994-11-17
EP0361910B1 (de) 1994-06-29
DK481689A (da) 1990-03-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee