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1861-08-20 |
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Improvement in potato-diggers |
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1952-07-18 |
1956-03-13 |
Smith Kline French Lab |
Sympathomimetic preparation
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1960-04-19 |
1962-11-20 |
Richardson Merrell Inc |
Sustained release tablet
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1965-02-12 |
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American Cyanamid Company |
Process for preparing oral sustained release granules
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1967-07-27 |
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Analgesic and antitussive compositions and methods
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1967-07-27 |
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Gruenenthal Chemie |
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1969-03-24 |
1982-08-17 |
University Of Delaware |
Polymeric article for dispensing drugs
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1969-03-24 |
1975-04-29 |
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Polymeric article for dispensing drugs
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GB1405088A
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1971-06-03 |
1975-09-03 |
Mundipharma Ag |
Slow release formulation
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1972-05-10 |
1975-06-20 |
Servier Lab |
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1972-05-16 |
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Slow release pharmaceutical compositions
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1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
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1973-09-28 |
1975-11-04 |
Sandoz Ag |
Patient ventilator apparatus
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DE2360796B2
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1973-12-06 |
1977-06-02 |
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1974-03-04 |
1976-08-10 |
Pennwalt Corporation |
1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters
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DE2426811A1
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1974-06-04 |
1976-01-08 |
Klinge Co Chem Pharm Fab |
Verfahren zur herstellung von retard-tabletten
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DE2426812A1
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1974-06-04 |
1976-01-02 |
Klinge Co Chem Pharm Fab |
Verfahren zur herstellung von granulaten
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1974-08-17 |
1980-07-17 |
Ludwig Heumann & Co Gmbh, 8500 Nuernberg |
Verfahren zur Herstellung von oral zu verabreichenden Arzneimitteln mit verzögerter Wirkungsfreigabe
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GB1478759A
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1974-11-18 |
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Alza Corp |
Process for forming outlet passageways in pills using a laser
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1975-05-29 |
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American Cyanamid Company |
High molecular weight polyester resin, the method of making the same and the use thereof as a pharmaceutical composition
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1975-11-17 |
1977-05-18 |
Sandoz Ag |
Neue galenische formen und verfahren zu deren herstellung
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1976-02-23 |
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1976-07-23 |
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1976-07-23 |
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Merrell Dow Pharmaceuticals Inc. |
Controlled release suppositories consisting essentially of a linear polymer particularly, polyvinyl pyrrolidones
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1977-04-15 |
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Hpm Corporation |
Extrusion apparatus and method
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1982-12-28 |
The Upjohn Company |
4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use
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1978-05-30 |
1980-10-28 |
Griffith Laboratories U.S.A., Inc. |
Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices
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EP0008083A1
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1978-08-15 |
1980-02-20 |
Ciba-Geigy Ag |
Verfahren zur Herstellung von Granulaten schwerschmelzbarer Zusatzstoffe für Kunststoffe, insbesondere von Pigmenten, durch thermische Rollgranulierung und die so erhaltenen Granulate
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CH637014A5
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1978-09-29 |
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Sandoz Ag |
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1979-06-08 |
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1979-07-05 |
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Yamanouchi Pharmaceutical Co. Ltd. |
Process for the production of sustained release pharmaceutical composition of solid medical material
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1979-12-10 |
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Hans Lowey |
Method and composition for the preparation of controlled long-acting pharmaceuticals
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IE49324B1
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1979-12-19 |
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Controlled release compositions
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JPS56140915A
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1980-04-07 |
1981-11-04 |
Yamanouchi Pharmaceut Co Ltd |
Pharmaceutical preparation for solid drug
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DE3024416C2
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1980-06-28 |
1982-04-15 |
Gödecke AG, 1000 Berlin |
Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
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1980-11-10 |
1982-08-31 |
Alza Corporation |
Drug delivery devices comprising erodible polymer and erosion rate modifier
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JPS57171428A
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1981-04-13 |
1982-10-22 |
Sankyo Co Ltd |
Preparation of coated solid preparation
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DE3124983A1
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1981-06-25 |
1983-01-20 |
Meditest Inst Fuer Medizinisch |
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1981-08-18 |
1983-02-15 |
Richard Hochschild |
Method for making a pharmaceutical and/or nutritional dosage form
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1981-12-18 |
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Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
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1983-06-21 |
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Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
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Sustained release diethylpropion compositions
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1982-06-21 |
1984-04-17 |
Euroceltique, S.A. |
Extended action controlled release compositions
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Constant release formulation
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Dry direct compression compositions for controlled release dosage forms
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1983-07-04 |
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Mitsui Petrochem Ind Ltd |
ポリプロピレン組成物
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1983-12-22 |
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Elan Corporation Plc |
Controlled absorption diltiazem formulation
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1984-01-03 |
1987-03-11 |
Merck & Co. Inc. |
Drug delivery device
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EP0152379A3
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1984-02-15 |
1986-10-29 |
Ciba-Geigy Ag |
Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
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GB8405112D0
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1984-02-28 |
1984-04-04 |
Akzo Nv |
Anti-arrhythmic amino-alcohols
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1984-05-31 |
1987-03-10 |
Eli Lilly And Company |
Rumen delivery device
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1984-07-23 |
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Erodible matrix for sustained release bioactive composition
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1985-01-26 |
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Percutaneous absorption accelerator for ionic water-soluble medicine
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1985-03-08 |
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Yamanouchi Pharmaceutical Co., Ltd. |
Controlled-release multiple units pharmaceutical formulation
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1985-05-03 |
1988-01-19 |
E. I. Du Pont De Nemours And Company |
Manufacture of hollow fine tubular drug delivery systems
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1985-05-09 |
1988-05-20 |
Rhone Poulenc Sante |
Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
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Miles Inc |
Verwendung von kalziumantagonisten zur anfertigung von zusammensetzungen fuer entziehungssymptome.
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GB8514665D0
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1985-06-11 |
1985-07-10 |
Eroceltique Sa |
Oral pharmaceutical composition
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1986-12-24 |
Teisan Seiyaku Kk |
徐放化製剤
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FR2585246A1
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1985-07-26 |
1987-01-30 |
Cortial |
Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
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Analgesic composition
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EP0223431B1
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1992-04-29 |
Imperial Chemical Industries Plc |
Apparatus and method for forming pellets
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1989-11-21 |
Warner Lambert Co. |
Confectionery delivery system for appetite suppressants
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Warner Lambert Co. |
Confectionery delivery system for antihistimines
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Confectionery delivery system for anti-cholesterolemics
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1985-12-20 |
1988-10-18 |
Warner-Lambert Company |
Confectionery delivery system for actives
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1985-12-20 |
1989-11-21 |
Warner Lambert Co. |
Confectionery delivery system for expectorants
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1985-12-20 |
1989-11-21 |
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Confectionery delivery system for laxatives, vitamins and antacids
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1985-12-20 |
1989-11-07 |
Warner-Lambert Company |
Confectionery delivery system for antipyretics
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1985-12-20 |
1989-11-21 |
Warner Lambert Co. |
Confectionery delivery system for antiarrhythmics
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1985-12-20 |
1989-11-21 |
Warner Lambert Co. |
Confectionery delivery system for antitussives
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JP2521504B2
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1985-12-27 |
1996-08-07 |
昭和電工株式会社 |
酵素の造粒法
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DE3602370A1
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1986-01-27 |
1987-08-06 |
Chrubasik Sigrun |
Verwendung von analgetica durch inhalation
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DE3602360A1
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1986-01-27 |
1987-07-30 |
Krupp Polysius Ag |
Seitenkratzer fuer schuettguthalde
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1986-02-10 |
1988-08-16 |
Zetachron, Inc. |
Buccal drug dosage form
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GB2186485B
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1986-02-13 |
1988-09-07 |
Ethical Pharma Ltd |
Slow release formulation
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1986-03-10 |
1991-02-19 |
American Cyanamid Company |
Method for the preparation of sustained released bolus formulation
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DE3610878A1
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1986-04-01 |
1987-10-08 |
Boehringer Ingelheim Kg |
Formlinge aus pellets
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DE3612212A1
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1986-04-11 |
1987-10-15 |
Basf Ag |
Verfahren zur herstellung von festen pharmazeutischen formen
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DE3612211A1
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1986-04-11 |
1987-10-15 |
Basf Ag |
Kontinuierliches verfahren zum tablettieren
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1986-04-15 |
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Warner-Lambert Company |
Pharmaceutical composition
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1986-06-05 |
1986-07-09 |
Euro Celtique Sa |
Pharmaceutical composition
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GB8613688D0
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1986-06-05 |
1986-07-09 |
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Pharmaceutical composition
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1986-06-10 |
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Zusammensetzung mit kontrollierter freisetzung von dihydrocodein.
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1986-06-16 |
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Johnson & Johnson Consumer Products, Inc. |
Bioadhesive extruded film for intra-oral drug delivery and process
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1986-07-10 |
1988-01-14 |
Gruenenthal Gmbh |
Neue verbindungen, diese enthaltende arzneimittel und verfahren zu deren herstellung
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1986-07-18 |
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Euroceltique, S.A. |
Controlled release bases for pharmaceuticals
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1986-07-18 |
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1986-07-18 |
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Controlled release bases for pharmaceuticals
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American Home Products Corporation (Del.) |
Spray dried acetaminophen
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1986-10-31 |
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Controlled release hydromorphone composition
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IE873172L
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1986-12-29 |
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Harvard College |
Continuous process for producing a comestible tablet
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1987-01-29 |
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Takeda Chemical Industries, Ltd. |
Spherical granules having core and their production
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1987-06-10 |
1988-10-20 |
Warner-Lambert Company |
Process for preparing a pharmaceutical composition
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1987-07-01 |
1988-06-09 |
Hoechst Ag |
Verfahren zur Umhuellung von Granulaten
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GB8717168D0
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1987-07-21 |
1987-08-26 |
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Controlled-release device
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1987-07-22 |
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Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
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1987-09-11 |
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E. R. Squibb & Sons, Inc. |
Pharmaceutical composition containing high drug load and method for preparing same
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1988-09-19 |
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Directly compressible sustained release excipient
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Active agent delivery device
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1988-02-01 |
1989-09-06 |
F.H. FAULDING & CO. LTD. |
Tetracycline dosage form
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1988-03-23 |
1989-06-27 |
International Flavors & Fragrances, Inc. |
Compositions and methods for controlled release of fragrance-bearing substances
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1988-04-15 |
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Basf Ag |
Verfahren zur herstellung pharmazeutischer mischungen
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1988-04-16 |
1995-12-05 |
Schwarz Pharma Ag |
Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture
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JP2681373B2
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1988-07-18 |
1997-11-26 |
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徐放性製剤の製造法
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1988-08-10 |
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Deutsche Gelatine-Fabriken Stoess & Co Gmbh, 6930 Eberbach, De |
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1988-08-19 |
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Himedics, Inc. |
Erythromycin microencapsulated granules
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1988-08-26 |
1988-09-28 |
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New compositions of matter
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1988-09-07 |
1990-03-15 |
Basf Ag |
Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
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1988-09-07 |
1990-03-15 |
Basf Ag |
Verfahren zur herstellung von pharmazeutischen tabletten
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Rhone Poulenc Rorer Ltd |
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1988-10-26 |
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Kabi Pharmacia Aktiebolaq |
Dosage form
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AU645003B2
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1988-11-08 |
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Takeda Chemical Industries Ltd. |
Sustained release preparations
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1988-11-11 |
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Pharmaceutical ion exchange resin composition
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IL92343A0
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1988-12-20 |
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Granulate for multiparticulate controlled release oral compositions,their preparation and oral pharmaceutical compositions containing them
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1988-12-29 |
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Slow release drug delivery granules and process for production thereof
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F. H. Faulding & Co. Limited |
Sustained release pharmaceutical composition
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Theophylline dosage form
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F. H. Faulding & Co. Limited |
Sustained release pharmaceutical composition
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CA2007181C
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1989-01-06 |
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Angelo Mario Morella |
Sustained release pharmaceutical composition
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CA2007055A1
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1989-01-06 |
1990-07-06 |
Garth Boehm |
Theophylline dosage form
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FR2642420B1
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1989-01-27 |
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Valpan Sa Labo Pharma |
Nouvelle forme galenique a liberation programmee contenant une association de sels ferreux, d'acide succinique et d'acide ascorbique
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Depomed Systems, Inc. |
Sustained-release oral drug dosage form
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Controlled release tablet containing water soluble medicament
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Method of combining active ingredients with polyvinyl acetates
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1989-05-05 |
1992-07-28 |
Kv Pharmaceutical Company |
Extended release pharmaceutical formulations
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Glatt Gmbh |
Microwave assisted fluidized bed processor
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Niro Atomizer As |
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1989-08-28 |
1991-10-17 |
Arizona Technology Development Corp., Tucson, Ariz. |
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1989-09-21 |
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Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
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1989-10-31 |
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Duquesne University Of The Holy Ghost |
Directly compressible granules having improved flow properties
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Abbott Lab |
Medications with delayed release
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Seiko Epson Corporation |
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1990-04-12 |
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1990-04-28 |
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1990-06-25 |
1993-02-02 |
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1990-06-25 |
1994-10-11 |
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1990-06-27 |
1993-11-29 |
Alkaloida Vegyeszeti Gyar |
Process for producing retarde pharmaceutical compositions
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1990-06-29 |
1993-07-09 |
Rhone Poulenc Nutrition Animale |
Procede de preparation de granules de principes actifs par extrusion.
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1990-08-01 |
1993-12-15 |
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1990-08-13 |
1991-07-30 |
Hpm Corporation |
Multi-channel extrusion screw with a zig-zag undercut barrier
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1990-08-24 |
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1990-10-05 |
1992-04-07 |
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Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH
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1990-10-08 |
1994-02-24 |
Sanol Arznei Schwarz Gmbh |
Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
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1990-10-16 |
1992-04-17 |
Kabi Pharmacia Ab |
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1990-10-16 |
1992-04-22 |
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Film-forming polymer compositions
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1990-10-22 |
1993-12-21 |
Revlon Consumer Products Corporation |
Encapsulated antiperspirant salts and deodorant/antiperspirants
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1990-12-14 |
1995-02-17 |
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1990-12-17 |
1993-08-31 |
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Screw-type extrusion granulating apparatus, especially for producing very fine granules
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1990-12-17 |
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1991-03-04 |
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Sandoz Ltd. |
Melt granulated compositions for preparing sustained release dosage forms
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1991-03-18 |
1993-12-28 |
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Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms
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1991-03-19 |
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Glatt Gmbh |
Apparatus and method for producing pellets by layering power onto particles
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1991-04-12 |
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1991-04-16 |
1992-11-17 |
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1991-05-28 |
1995-01-10 |
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Vectorpharma Int |
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1991-08-23 |
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Gillette Canada, Inc. |
Sustained-release matrices for dental application
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1991-09-06 |
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Johnson & Johnson |
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1991-09-11 |
1993-06-01 |
Euroceltique, S.A. |
Controlled release matrix suppository for pharmaceuticals
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1991-10-04 |
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1991-10-30 |
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Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
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1991-11-22 |
1992-11-10 |
Schering Corporation |
Controlled release flutamide composition
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1991-11-23 |
1993-05-27 |
Basf Ag |
Feste pharmazeutische retardform
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1991-11-27 |
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Controlled release oxycodone compositions
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1991-12-05 |
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Pitman-Moore, Inc. |
A carbohydrate glass matrix for the sustained release of a therapeutic agent
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GB2281204A
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1993-07-27 |
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Sustained release morphine compositions
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1991-12-24 |
1993-12-28 |
Euroceltigue, S.A. |
Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
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1993-11-23 |
1998-06-24 |
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A method of preparing pharmaceutical compositions by melt pelletisation
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1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
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1992-01-27 |
1994-02-15 |
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Stabilized controlled release formulations having acrylic polymer coating
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1992-02-14 |
1992-12-01 |
Warner-Lambert Company |
Semi-enteric drug delivery systems and methods for preparing same
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1992-03-20 |
1993-09-21 |
Kabi Pharmacia Ab |
Metod för framställning av pellets med fördröjd frisättning
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1992-06-19 |
1993-11-16 |
Digestive Care Inc. |
Compositions of gastric acid-resistant microspheres containing buffered bile acids
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1992-06-26 |
1994-09-27 |
Merck & Co., Inc. |
Spheronization process using charged resins
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1992-06-26 |
1995-07-04 |
Mcneil-Ppc, Inc. |
Rotomelt granulation
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1992-08-19 |
1994-02-24 |
Kali Chemie Pharma Gmbh |
Pankreatinmikropellets
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1992-10-16 |
2002-09-11 |
Nippon Shinyaku Company, Limited |
Method of manufacturing wax matrices
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1992-10-30 |
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Asta Medica Ag |
Kombinationspräparat aus Flupirtin und Morphin zur Behandlung von Schmerzen und zur Vermeidung der Morphin-Abhängigkeit
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1993-01-28 |
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Virginia Commonwealth University Medical College |
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1993-05-10 |
1998-03-10 |
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Controlled release formulation comprising tramadol
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1993-05-18 |
1996-10-30 |
Istituto Biochimico Italiano |
Composizione farmaceutica a lento rilascio contenente come sostanza attiva un acido biliare
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1993-07-01 |
1998-12-06 |
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Continuous release dosage form containing morphine and a method of preparing such sustained release unit dosage forms
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1993-09-03 |
1997-09-18 |
Gruenenthal Gmbh |
Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
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1993-11-23 |
1996-03-19 |
Euro-Celtique, S.A. |
Immediate release tablet cores of insoluble drugs having sustained-release coating
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1993-11-23 |
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1993-11-23 |
1999-04-06 |
Euro-Celtique, S.A. |
Pharmaceutical multiparticulates
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1993-12-20 |
1995-12-19 |
Tennessee Valley Authority |
System for improving material release profiles
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1994-01-12 |
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株式会社日本製鋼所 |
二軸混練押出機
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1994-03-14 |
1998-12-01 |
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Controlled release diamorphine formulation
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1994-03-23 |
1995-03-07 |
Ortho Pharmaceutical Corporation |
Multilayered controlled release pharmaceutical dosage form
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1994-05-30 |
1995-12-07 |
Bayer Ag |
Thermisches Granulierverfahren
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1994-06-14 |
1996-10-22 |
Fuisz Technologies Ltd. |
Delivery of controlled-release systems(s)
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1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
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