NO310543B1 - Nanopartikkelformig preparat og fremgangsmåte for dets fremstilling - Google Patents

Nanopartikkelformig preparat og fremgangsmåte for dets fremstilling Download PDF

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Publication number
NO310543B1
NO310543B1 NO19934424A NO934424A NO310543B1 NO 310543 B1 NO310543 B1 NO 310543B1 NO 19934424 A NO19934424 A NO 19934424A NO 934424 A NO934424 A NO 934424A NO 310543 B1 NO310543 B1 NO 310543B1
Authority
NO
Norway
Prior art keywords
tyloxapol
agent
nanoparticulate
preparation
particle size
Prior art date
Application number
NO19934424A
Other languages
English (en)
Norwegian (no)
Other versions
NO934424D0 (no
NO934424L (no
Inventor
Siegfried K June
Original Assignee
Elan Pharma Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
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Application filed by Elan Pharma Int Ltd filed Critical Elan Pharma Int Ltd
Publication of NO934424D0 publication Critical patent/NO934424D0/no
Publication of NO934424L publication Critical patent/NO934424L/no
Publication of NO310543B1 publication Critical patent/NO310543B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0476Particles, beads, capsules, spheres
    • A61K49/0485Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A61K49/049Surface-modified nanoparticles, e.g. immune-nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19934424A 1992-12-15 1993-12-06 Nanopartikkelformig preparat og fremgangsmåte for dets fremstilling NO310543B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/990,874 US5429824A (en) 1992-12-15 1992-12-15 Use of tyloxapole as a nanoparticle stabilizer and dispersant

Publications (3)

Publication Number Publication Date
NO934424D0 NO934424D0 (no) 1993-12-06
NO934424L NO934424L (no) 1994-06-16
NO310543B1 true NO310543B1 (no) 2001-07-23

Family

ID=25536608

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19934424A NO310543B1 (no) 1992-12-15 1993-12-06 Nanopartikkelformig preparat og fremgangsmåte for dets fremstilling

Country Status (24)

Country Link
US (1) US5429824A (fr)
EP (1) EP0602702B1 (fr)
JP (3) JPH06199658A (fr)
KR (1) KR100320390B1 (fr)
AT (1) ATE178788T1 (fr)
AU (1) AU665669B2 (fr)
CA (1) CA2108192C (fr)
CZ (1) CZ274793A3 (fr)
DE (1) DE69324456T2 (fr)
DK (1) DK0602702T3 (fr)
ES (1) ES2130217T3 (fr)
FI (1) FI935395A (fr)
GR (1) GR3030059T3 (fr)
HU (1) HU219333B (fr)
IL (1) IL107874A (fr)
MX (1) MX9306010A (fr)
MY (1) MY110186A (fr)
NO (1) NO310543B1 (fr)
NZ (1) NZ248726A (fr)
PH (1) PH29957A (fr)
RU (1) RU2124886C1 (fr)
SK (1) SK280614B6 (fr)
TW (1) TW440451B (fr)
UA (1) UA27760C2 (fr)

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* Cited by examiner, † Cited by third party
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