NO2785538T3 - - Google Patents
Info
- Publication number
- NO2785538T3 NO2785538T3 NO12794266A NO12794266A NO2785538T3 NO 2785538 T3 NO2785538 T3 NO 2785538T3 NO 12794266 A NO12794266 A NO 12794266A NO 12794266 A NO12794266 A NO 12794266A NO 2785538 T3 NO2785538 T3 NO 2785538T3
- Authority
- NO
- Norway
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Humanized animals, e.g. knockin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0368—Animal model for inflammation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461989757P | 2014-05-07 | 2014-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2785538T3 true NO2785538T3 (fr) | 2018-08-04 |
Family
ID=53284509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO12794266A NO2785538T3 (fr) | 2014-05-07 | 2012-11-22 |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US9565841B2 (fr) |
| EP (3) | EP3281521B1 (fr) |
| JP (4) | JP6640740B2 (fr) |
| KR (2) | KR102473565B1 (fr) |
| CN (2) | CN110269047B (fr) |
| AU (2) | AU2015255977B2 (fr) |
| BR (1) | BR112016025745A2 (fr) |
| CA (2) | CA3207834A1 (fr) |
| CY (2) | CY1119773T1 (fr) |
| DK (2) | DK3027015T3 (fr) |
| ES (2) | ES2656529T3 (fr) |
| HR (2) | HRP20211455T1 (fr) |
| HU (2) | HUE055860T2 (fr) |
| IL (3) | IL248358B2 (fr) |
| LT (2) | LT3281521T (fr) |
| MX (1) | MX370672B (fr) |
| NO (1) | NO2785538T3 (fr) |
| PH (1) | PH12016502058A1 (fr) |
| PL (2) | PL3281521T3 (fr) |
| PT (2) | PT3281521T (fr) |
| RS (2) | RS62345B1 (fr) |
| RU (1) | RU2703139C2 (fr) |
| SG (2) | SG11201608570YA (fr) |
| SI (2) | SI3281521T1 (fr) |
| WO (1) | WO2015171861A1 (fr) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2785538T3 (fr) | 2014-05-07 | 2018-08-04 | ||
| BR112016029650A2 (pt) | 2014-06-19 | 2017-10-24 | Regeneron Pharma | roedor, polipeptídeo pd-1, célula isolada ou tecido de roedor, célula-tronco embrionária de roedor, métodos de produzir um roedor, de reduzir o crescimento de tumor em um roedor, de matar células tumorais em um roedor e de avaliar as propriedades farmacocinéticas de uma droga que direciona pd-1 humano, e, modelo de tumor de roedor? |
| JP6899322B2 (ja) * | 2014-09-17 | 2021-07-07 | エリコン・サーフェス・ソリューションズ・アクチェンゲゼルシャフト，プフェフィコーンＯｅｒｌｉｋｏｎ Ｓｕｒｆａｃｅ Ｓｏｌｕｔｉｏｎｓ Ａｇ， Ｐｆａｅｆｆｉｋｏｎ | 改善された耐摩耗性を有する２層コーティングされた切削工具を製造するための方法 |
| AU2015353705C9 (en) | 2014-11-24 | 2022-09-01 | Regeneron Pharmaceuticals, Inc. | Non-human animals expressing humanized CD3 complex |
| DK3466255T3 (da) | 2014-12-05 | 2021-05-03 | Regeneron Pharma | Ikke-humane dyr med en humaniseret klynge af differentiering af 47-gen |
| AU2016358101B2 (en) | 2015-11-20 | 2022-12-01 | Regeneron Pharmaceuticals, Inc. | Non-human animals having a humanized Lymphocyte-activation gene 3 |
| AU2017213627B2 (en) | 2016-02-04 | 2022-05-19 | Regeneron Pharmaceuticals, Inc. | Non-human animals having an engineered ANGPTL8 gene |
| PT3422845T (pt) * | 2016-02-29 | 2021-08-26 | Regeneron Pharma | Roedores com um gene tmprss humanizado |
| TWI784988B (zh) | 2016-12-01 | 2022-12-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| SG11201909457XA (en) | 2017-04-13 | 2019-11-28 | Regeneron Pharma | Treatment and inhibition of inflammatory lung diseases in patients having risk alleles in the genes encoding il33 and il1rl1 |
| JP2020527332A (ja) | 2017-06-12 | 2020-09-10 | ブルーフィン バイオメディシン， インコーポレイテッド | 抗−ｉｌ１ｒａｐ抗体および抗体薬物コンジュゲート |
| CN116064611A (zh) | 2017-11-30 | 2023-05-05 | 瑞泽恩制药公司 | 包含人源化trkb基因座的非人动物 |
| TWI829679B (zh) | 2018-03-26 | 2024-01-21 | 美商再生元醫藥公司 | 用於測試治療藥劑之人類化囓齒動物 |
| IL307286A (en) | 2018-04-11 | 2023-11-01 | Regeneron Pharma | Methods and preparations for quantification of IL-33 |
| JP7048051B2 (ja) | 2018-07-11 | 2022-04-05 | 正徳 染井 | 痒みを軽減するアトピー性皮膚炎治療剤 |
| CN116200426A (zh) | 2018-07-16 | 2023-06-02 | 瑞泽恩制药公司 | Ditra疾病的非人动物模型及其用途 |
| WO2020074005A1 (fr) | 2018-10-12 | 2020-04-16 | Beijing Biocytogen Co., Ltd | Animal non humain génétiquement modifié avec des gènes humains ou chimériques |
| CN111218425B (zh) * | 2019-01-17 | 2022-02-08 | 百奥赛图(北京)医药科技股份有限公司 | 人源化转基因动物 |
| SG11202108454RA (en) | 2019-04-04 | 2021-09-29 | Regeneron Pharma | Non-human animals comprising a humanized coagulation factor 12 locus |
| EP3801011A1 (fr) | 2019-06-04 | 2021-04-14 | Regeneron Pharmaceuticals, Inc. | Animaux non humains comprenant un locus ttr humanisé ayant une mutation bêta-slip et procédés d'utilisation |
| CN113939595A (zh) | 2019-06-07 | 2022-01-14 | 瑞泽恩制药公司 | 包括人源化白蛋白基因座的非人动物 |
| WO2021018198A1 (fr) * | 2019-07-29 | 2021-02-04 | Beijing Biocytogen Co., Ltd | Animal non humain génétiquement modifié avec une il33 humaine ou chimérique |
| US20220312749A1 (en) * | 2019-08-09 | 2022-10-06 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric il2ra |
| CN112779285B (zh) * | 2019-11-11 | 2023-01-06 | 百奥赛图(北京)医药科技股份有限公司 | 人源化il-10和il-10ra基因改造动物的构建方法和应用 |
| WO2021129766A1 (fr) * | 2019-12-25 | 2021-07-01 | 江苏集萃药康生物科技股份有限公司 | Modèle de souris humanisé il-15 et ses utilisations |
| CA3169272A1 (fr) * | 2020-01-28 | 2021-08-05 | Regeneron Pharmaceuticals, Inc. | Animaux non humains comprenant un locus pnpla3 humanise et procedes d'utilisation |
| CN111149767B (zh) * | 2020-02-24 | 2021-07-20 | 中南大学湘雅二医院 | 一种人源化皮肤型红斑狼疮小鼠模型的构建方法和应用 |
| CN113527485A (zh) * | 2020-04-17 | 2021-10-22 | 上海麦济生物技术有限公司 | 抗人白细胞介素-4受体α抗体及其制备方法和应用 |
| CN111808882B (zh) * | 2020-09-01 | 2020-12-29 | 北京百奥赛图基因生物技术有限公司 | Il7r基因人源化改造的动物模型的构建方法及其应用 |
| CN111793646B (zh) * | 2020-09-08 | 2021-01-15 | 北京百奥赛图基因生物技术有限公司 | Il1r1基因人源化改造的非人动物的构建方法及其应用 |
| CN111926039B (zh) * | 2020-09-23 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | Il-13基因人源化的非人动物的构建方法和应用 |
| EP4262374A1 (fr) * | 2020-12-21 | 2023-10-25 | Regeneron Pharmaceuticals, Inc. | Animaux non humains ayant un gène tslp humanisé, un gène récepteur tslp humanisé et/ou un gène il7ra humanisé |
| CN114835798B (zh) * | 2021-05-28 | 2024-02-23 | 百奥赛图(北京)医药科技股份有限公司 | Cd36基因人源化非人动物的构建方法及应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990005183A1 (fr) * | 1988-10-31 | 1990-05-17 | Immunex Corporation | Recepteurs d'interleukine-4 |
| CA2827654C (fr) | 2004-10-19 | 2019-04-02 | Regeneron Pharmaceuticals, Inc. | Methode de production d'un animal homozygote pour une modification genetique |
| JP2007252370A (ja) * | 2006-02-22 | 2007-10-04 | Institute Of Physical & Chemical Research | Ｉｌ−４初期発現系トランスジェニック非ヒト動物およびその利用 |
| US20110016543A1 (en) * | 2008-12-04 | 2011-01-20 | Sigma-Aldrich Co. | Genomic editing of genes involved in inflammation |
| JP2012531896A (ja) * | 2009-06-29 | 2012-12-13 | チェン，チンフェン | ヒト化非ヒト哺乳動物を製造する方法 |
| AU2010275432A1 (en) * | 2009-07-24 | 2012-02-02 | Sigma-Aldrich Co. Llc. | Method for genome editing |
| RU2425880C2 (ru) * | 2009-07-30 | 2011-08-10 | Учреждение Российской академии наук Институт общей генетики им. Н.И. Вавилова РАН | Способ получения трансгенных мышей |
| ES2591107T3 (es) | 2009-10-06 | 2016-11-24 | Regeneron Pharmaceuticals, Inc. | Ratones modificados genéticamente e injerto |
| RU2730643C2 (ru) | 2011-02-15 | 2020-08-24 | Ридженерон Фармасьютикалз, Инк. | Гуманизированные m-csf мыши |
| DK2818478T3 (en) * | 2011-10-28 | 2017-05-22 | Regeneron Pharma | HUMANIZED IL-6 AND IL-6 RECEPTOR |
| LT3590332T (lt) | 2011-10-28 | 2022-08-10 | Regeneron Pharmaceuticals, Inc. | Genetiškai modifikuotos pelės, ekspresuojančios chimerines pagrindinio audinių dermės komplekso (mhc) ii molekules |
| CN107254480B (zh) | 2011-10-28 | 2021-08-10 | 瑞泽恩制药公司 | 制备主要组织相容性复合物基因修饰小鼠的方法 |
| US8962913B2 (en) | 2012-06-18 | 2015-02-24 | Regeneron Pharmaceuticals, Inc. | Humanized IL-7 rodents |
| ES2900342T3 (es) * | 2012-08-21 | 2022-03-16 | Sanofi Biotechnology | Métodos para tratar o prevenir el asma administrando un antagonista de IL-4R |
| KR102594390B1 (ko) | 2012-09-07 | 2023-10-27 | 예일 유니버시티 | 유전적으로 변형된 비-인간 동물 및 이것들의 사용 방법 |
| CN104918483B (zh) | 2012-11-05 | 2018-05-11 | 再生元制药公司 | 生成及使用经遗传修饰的非人动物的方法 |
| SI2958938T1 (sl) | 2013-02-20 | 2019-08-30 | Regeneron Pharmaceuticals, Inc. | Miši, ki izražajo humanizirane koreceptorje za celice T |
| CN105164154B (zh) | 2013-02-22 | 2019-06-07 | 瑞泽恩制药公司 | 表达人源化主要组织相容性复合物的小鼠 |
| JO3532B1 (ar) | 2013-03-13 | 2020-07-05 | Regeneron Pharma | الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها |
| TR201901782T4 (tr) | 2013-09-23 | 2019-03-21 | Regeneron Pharma | İnsanlaştirilmiş bi̇r si̇nyal düzenleyi̇ci̇ protei̇n geni̇ne sahi̇p olan i̇nsan dişi hayvanlar. |
| MX2016004781A (es) | 2013-10-15 | 2016-07-26 | Regeneron Pharma | Il-15 humanizada en animales. |
| CA2929846C (fr) | 2013-11-19 | 2020-09-15 | Regeneron Pharmaceuticals, Inc. | Animaux non humains ayant un gene de facteur activant les cellules b humanise |
| JP6484237B2 (ja) | 2013-11-19 | 2019-03-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | ヒト化増殖誘導リガンド遺伝子を有する非ヒト動物 |
| DK3129400T3 (da) | 2014-04-08 | 2020-06-08 | Regeneron Pharma | Ikke-humane dyr med humaniserede Fc-gamma-receptorer |
| CA3225091A1 (fr) | 2014-05-05 | 2015-11-12 | Regeneron Pharmaceuticals, Inc. | Animaux porteurs des sequences c5 et c3 humanisees |
| NO2785538T3 (fr) * | 2014-05-07 | 2018-08-04 |
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2012
- 2012-11-22 NO NO12794266A patent/NO2785538T3/no unknown
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2015
- 2015-05-07 ES ES15727106.5T patent/ES2656529T3/es active Active
- 2015-05-07 DK DK15727106.5T patent/DK3027015T3/en active
- 2015-05-07 KR KR1020167034170A patent/KR102473565B1/ko active IP Right Grant
- 2015-05-07 LT LTEP17193855.8T patent/LT3281521T/lt unknown
- 2015-05-07 SG SG11201608570YA patent/SG11201608570YA/en unknown
- 2015-05-07 EP EP17193855.8A patent/EP3281521B1/fr active Active
- 2015-05-07 DK DK17193855.8T patent/DK3281521T3/da active
- 2015-05-07 RS RS20211141A patent/RS62345B1/sr unknown
- 2015-05-07 PT PT171938558T patent/PT3281521T/pt unknown
- 2015-05-07 JP JP2016566656A patent/JP6640740B2/ja active Active
- 2015-05-07 RS RS20180131A patent/RS57073B1/sr unknown
- 2015-05-07 CN CN201910691834.4A patent/CN110269047B/zh active Active
- 2015-05-07 IL IL248358A patent/IL248358B2/en unknown
- 2015-05-07 EP EP15727106.5A patent/EP3027015B1/fr active Active
- 2015-05-07 KR KR1020227041893A patent/KR102517112B1/ko active IP Right Grant
- 2015-05-07 BR BR112016025745-6A patent/BR112016025745A2/pt not_active Application Discontinuation
- 2015-05-07 PT PT157271065T patent/PT3027015T/pt unknown
- 2015-05-07 AU AU2015255977A patent/AU2015255977B2/en active Active
- 2015-05-07 HU HUE17193855A patent/HUE055860T2/hu unknown
- 2015-05-07 US US14/706,319 patent/US9565841B2/en active Active
- 2015-05-07 SI SI201531703T patent/SI3281521T1/sl unknown
- 2015-05-07 HR HRP20211455TT patent/HRP20211455T1/hr unknown
- 2015-05-07 WO PCT/US2015/029638 patent/WO2015171861A1/fr active Application Filing
- 2015-05-07 PL PL17193855T patent/PL3281521T3/pl unknown
- 2015-05-07 SG SG10201912354PA patent/SG10201912354PA/en unknown
- 2015-05-07 HU HUE15727106A patent/HUE038028T2/hu unknown
- 2015-05-07 CA CA3207834A patent/CA3207834A1/fr active Pending
- 2015-05-07 PL PL15727106T patent/PL3027015T3/pl unknown
- 2015-05-07 LT LTEP15727106.5T patent/LT3027015T/lt unknown
- 2015-05-07 MX MX2016014563A patent/MX370672B/es active IP Right Grant
- 2015-05-07 IL IL297105A patent/IL297105B2/en unknown
- 2015-05-07 RU RU2016143376A patent/RU2703139C2/ru active
- 2015-05-07 SI SI201530162T patent/SI3027015T1/en unknown
- 2015-05-07 ES ES17193855T patent/ES2887852T3/es active Active
- 2015-05-07 CN CN201580036907.6A patent/CN106470545B/zh active Active
- 2015-05-07 EP EP21166663.1A patent/EP3906781A1/fr active Pending
- 2015-05-07 CA CA2947307A patent/CA2947307C/fr active Active
- 2015-07-06 US US14/791,978 patent/US9743647B2/en active Active
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2016
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2017
- 2017-07-14 US US15/649,702 patent/US10588298B2/en active Active
- 2017-09-15 US US15/705,326 patent/US10477842B2/en active Active
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2018
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- 2018-02-08 HR HRP20180242TT patent/HRP20180242T1/hr unknown
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2019
- 2019-10-07 US US16/594,537 patent/US11109578B2/en active Active
- 2019-12-26 JP JP2019235722A patent/JP6838131B2/ja active Active
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2021
- 2021-02-10 JP JP2021019538A patent/JP7145250B2/ja active Active
- 2021-08-05 US US17/394,492 patent/US11963521B2/en active Active
- 2021-08-18 AU AU2021218060A patent/AU2021218060B2/en active Active
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2022
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- 2022-09-16 JP JP2022147925A patent/JP2022171841A/ja active Pending
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2023
- 2023-07-30 IL IL304841A patent/IL304841A/en unknown